Social Neuroscience

The social environment has an enormous influence in altering behavior, neuroendocrine function, immune system activity, and cardiovascular and metabolic function. Improving the social environment has an enormous and unrealized potential for altering brain function and systemic physiology to improve physical and mental health and to prevent or slow the course of disease.

This volume presents articles stemming from the 90th Annual Conference of the Association for Research in Nervous and Mental Disease, which focused on the advances in our understanding of gene–environment interactions and their impact on the functioning of the body and mind. The volume aims to advance knowledge of the neural bases underlying positive and adverse social interactions and the impact of these social experiences on the brain and body. A broad range of topics is covered, from fear conditioning to the implementation of treatment strategies in the workplace. The volume also highlights the implications of social experiences and stress on basic neuroscience and physiology, and the potential translational nature of such findings to the clinic and general public.

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1. Changing Perspectives in Three Disciplines 1

THE SOCIAL BRAIN

2. The Evolution, Structure, and Functioning of the Social Brain 29

3. The Neurology of Human Nature: Implications for the Sociological Analysis of Health and Well-Being 41

4. In Search of the Functional Neuroanatomy of Social Disturbance in Schizophrenia 88

5. Social Neuroscience and Psychopathology: Identifying the Relationship between Neural Function, Social Cognition, and Social Behavior 123

THE SOCIAL MIND

Color Plates

6. The Mind and Social Cognition 149

7. Social Cognition in Schizophrenia: Where We Are and Where We Are Going 161

8. Social Cognition in Those at High Risk of Psychosis 187

9. Criticism and the Course of Mental Disorders 208

THE SOCIAL WORLD

10. The Social Brain in a Social World 231

11. Linking the Social Brain to the Social World through Network Connections 247

12. Functional and Structural Correlates of Early Severe Social Deprivation 280

13. Violence, Cognition, and Neighborhood Inequality in America 320

14. The Normal Pain of the Social Brain: Confusing Depressive Disorder with Normal Sadness 340

15. Cognitive Enhancement Therapy for Improving the Social Brain and Cognition in Schizophrenia 364

16. Conclusions 395

Glossary 409

Acknowledgments 417

Contributors 419

Figure Credits 421

Index 425

Bruce Sherman McEwen is an American neuroendocrinologist and head of the Harold and Margaret Milliken Hatch Laboratory of Neuroendocrinology at Rockefeller University. He is known for his work on the effects of environmental and psychological stress, having coined the term allostatic load. Huda Akil is the editor of Social Neuroscience: Gene, Environment, Brain, Body, Volume 1231, published by Wiley.