{"product_id":"radiopharmaceuticals-for-positron-emission-tomography-volume-1-isbn-9780470588956","title":"Radiopharmaceuticals for Positron Emission Tomography, Volume 1","description":"\u003cb\u003eThe ultimate reference guide to the synthesis of radiopharmaceuticals\u003c\/b\u003e  \u003cp\u003eThe \u003ci\u003eRadiochemical Syntheses\u003c\/i\u003e series provides scientists and professionals with a comprehensive reference to proven synthetic methods for radiochemical reactions, along with step-by-step guidance on how to replicate these syntheses in the laboratory.\u003c\/p\u003e \u003cp\u003eVolume 1 in the series focuses on the synthesis and purification of radiopharmaceuticals in clinical use today. It brings together in one complete, self-contained volume a collection of monographs containing a wealth of practical information from across the literature, demonstrating in meticulous detail how to prepare radiopharmaceuticals for positron emission tomography (PET) imaging, especially in tumor studies, cardiology, and neuroscience.\u003c\/p\u003e \u003cp\u003eReaders have key experimental details culled from the literature at their fingertips, greatly simplifying the process of qualifying a site for the clinical production of new radiopharmaceuticals.\u003c\/p\u003e \u003cp\u003eContributors ix\u003c\/p\u003e \u003cp\u003eForeword xvii\u003c\/p\u003e \u003cp\u003ePreface xix\u003c\/p\u003e \u003cp\u003eAbbreviations xxi\u003c\/p\u003e \u003cp\u003e\u003cb\u003ePart I Fluorine-18 Labeled Radiopharmaceuticals 1\u003c\/b\u003e\u003c\/p\u003e \u003cp\u003e1. Synthesis of [\u003csup\u003e18\u003c\/sup\u003eF]-Fluorodeoxyglucose ([\u003csup\u003e18\u003c\/sup\u003eF]FDG) 3\u003cbr\u003e\u003ci\u003eMichelle L. Richards and Peter J. H. Scott\u003c\/i\u003e\u003c\/p\u003e \u003cp\u003e2. Synthesis of Sodium [\u003csup\u003e18\u003c\/sup\u003eF]Fluoride (Na[\u003csup\u003e18\u003c\/sup\u003eF]F) 15\u003cbr\u003e\u003ci\u003eBrian G. Hockley and Peter J. H. Scott\u003c\/i\u003e\u003c\/p\u003e \u003cp\u003e3. Radiosynthesis of 3_-Deoxy-3_-[\u003csup\u003e18\u003c\/sup\u003eF]Fluorothymidine ([\u003csup\u003e18\u003c\/sup\u003eF]FLT) 21\u003cbr\u003e\u003ci\u003eHartmuth C. Kolb, Henry C. Padgett, Steve Zigler, Jim Patanella, Fanrong Mu, Umesh B. Gangadharmath, Vani P. Mocharla, Peter J. H. Scott, and Joseph C. Walsh\u003c\/i\u003e\u003c\/p\u003e \u003cp\u003e4. Synthesis of [\u003csup\u003e18\u003c\/sup\u003eF]Fluoroazomycin Arabinoside ([\u003csup\u003e18\u003c\/sup\u003eF]FAZA) 31\u003cbr\u003e\u003ci\u003eBrian G. Hockley and Peter J. H. Scott\u003c\/i\u003e\u003c\/p\u003e \u003cp\u003e5. Synthesis of [\u003csup\u003e18\u003c\/sup\u003eF]Fluoromisonidazole (1-(2-Hydroxy-3-[\u003csup\u003e18\u003c\/sup\u003eF]Fluoropropyl)-2-Nitroimidazole, [\u003csup\u003e18\u003c\/sup\u003eF]FMISO) 41\u003cbr\u003e\u003ci\u003ePatrick J. Riss, Valentina Ferrari, Robert Bielik, Roberto Canales-Candela, Rob Smith, and Franklin I. Aigbirhio\u003c\/i\u003e\u003c\/p\u003e \u003cp\u003e6. Synthesis of [\u003csup\u003e18\u003c\/sup\u003eF]FPPRGD2 51\u003cbr\u003e\u003ci\u003eShuanglong Liu, Frederick T. Chin, Zhen Cheng, and Xiaoyuan Chen\u003c\/i\u003e\u003c\/p\u003e \u003cp\u003e7. Synthesis of [\u003csup\u003e18\u003c\/sup\u003eF]Fluorocholine ([\u003csup\u003e18\u003c\/sup\u003eF]FCH) 61\u003cbr\u003e\u003ci\u003eDavid Kryza\u003c\/i\u003e\u003c\/p\u003e \u003cp\u003e8. Clinical Manufacturing of [\u003csup\u003e18\u003c\/sup\u003eF]-16-\u003ci\u003eα\u003c\/i\u003e-Fluoroestradiol ([\u003csup\u003e18\u003c\/sup\u003eF]FES) 69\u003cbr\u003e\u003ci\u003ePiyush Kumar and John R. Mercer\u003c\/i\u003e\u003c\/p\u003e \u003cp\u003e9. Synthesis of \u003ci\u003eN\u003c\/i\u003e-Succinimidyl 4-[\u003csup\u003e18\u003c\/sup\u003eF]Fluorobenzoate ([\u003csup\u003e18\u003c\/sup\u003eF]SFB) 81\u003cbr\u003e\u003ci\u003eXia Shao\u003c\/i\u003e\u003c\/p\u003e \u003cp\u003e10. Synthesis of 4-(2_-Methoxyphenyl)-1-[2_-(\u003ci\u003eN\u003c\/i\u003e-2__Pyridinyl)-\u003ci\u003ep\u003c\/i\u003e-[\u003csup\u003e18\u003c\/sup\u003eF]Fluorobenzamido]Ethylpiperazine [\u003csup\u003e18\u003c\/sup\u003eF]MPPF 87\u003cbr\u003e\u003ci\u003eMarion Alvarez and Didier Le Bars\u003c\/i\u003e\u003c\/p\u003e \u003cp\u003e11. Synthesis of [\u003csup\u003e18\u003c\/sup\u003eF]-Fallypride 95\u003cbr\u003e\u003ci\u003eLaurent Brichard, Valentina Ferrari, Rob Smith, and Franklin I. Aigbirhio\u003c\/i\u003e\u003c\/p\u003e \u003cp\u003e12. Synthesis of [\u003csup\u003e18\u003c\/sup\u003eF]Fluoroethyltyrosine (\u003csup\u003e18\u003c\/sup\u003eF-FET) 103\u003cbr\u003e\u003ci\u003eYi Zhao, Amar Alfteimi, and Maaz Zuhayra\u003c\/i\u003e\u003c\/p\u003e \u003cp\u003e13. Synthesis of [\u003csup\u003e18\u003c\/sup\u003eF]Flumazenil ([\u003csup\u003e18\u003c\/sup\u003eF]FZ) 111\u003cbr\u003e\u003ci\u003eRalf Schirrmacher, Alexey Kostikov, Gassan Massaweh, Miriam Kovacevic, Carmen Wängler, and Alexander Thiel\u003c\/i\u003e\u003c\/p\u003e \u003cp\u003e14. Synthesis of 6-[\u003csup\u003e18\u003c\/sup\u003eF]Fluorodopamine (6-[\u003csup\u003e18\u003c\/sup\u003eF]FDA) 125\u003cbr\u003e\u003ci\u003eMichael A. Channing, John L. Musachio, and Jozef J. Kusmierz\u003c\/i\u003e\u003c\/p\u003e \u003cp\u003e15. Synthesis of 2-([\u003csup\u003e18\u003c\/sup\u003eF]Fluoro)-3-[(2\u003ci\u003eS\u003c\/i\u003e)-2-Azetidinylmethoxy]Pyridine ([\u003csup\u003e18\u003c\/sup\u003eF]2FA) 139\u003cbr\u003e\u003ci\u003eHayden T. Ravert, Daniel P. Holt, and Robert F. Dannals\u003c\/i\u003e\u003c\/p\u003e \u003cp\u003e16. Synthesis of [\u003csup\u003e18\u003c\/sup\u003eF]-Substance-P Antagonist-Receptor Quantifier ([\u003csup\u003e18\u003c\/sup\u003eF]SPA-RQ) 155\u003cbr\u003e\u003ci\u003eSofie Celen, Kim Serdons, Tjibbe de Groot, Terence G. Hamill, and Guy Bormans\u003c\/i\u003e\u003c\/p\u003e \u003cp\u003e\u003cb\u003ePart II\u003c\/b\u003e \u003cb\u003eCarbon-11 Labeled Radiopharmaceuticals \u003c\/b\u003e\u003cb\u003e167\u003c\/b\u003e\u003c\/p\u003e \u003cp\u003e17. Synthesis of [\u003csup\u003e11\u003c\/sup\u003eC]Choline Chloride ([\u003csup\u003e11\u003c\/sup\u003eC]CHL) 169\u003cbr\u003e\u003ci\u003eBrian G. Hockley, Bradford Henderson, and Xia Shao\u003c\/i\u003e\u003c\/p\u003e \u003cp\u003e18. Synthesis of 2-(4-\u003ci\u003eN\u003c\/i\u003e-[\u003csup\u003e11\u003c\/sup\u003eC]Methylaminophenyl)-6-Hydroxybenzothiazole ([\u003csup\u003e11\u003c\/sup\u003eC]6-OH-BTA-1; [\u003csup\u003e11\u003c\/sup\u003eC]PIB) 177\u003cbr\u003e\u003ci\u003eCécile Philippe, Markus Mitterhauser, and Wolfgang Wadsak\u003c\/i\u003e\u003c\/p\u003e \u003cp\u003e19. Synthesis of [\u003csup\u003e11\u003c\/sup\u003eC]-meta-Hydroxyephedrine ([\u003csup\u003e11\u003c\/sup\u003eC]MHED) 191\u003cbr\u003e\u003ci\u003eFilippo Lodi, Assunta Carpinelli, Claudio Malizia, and Stefano Boschi\u003c\/i\u003e\u003c\/p\u003e \u003cp\u003e20. Synthesis of l-[methyl-\u003csup\u003e11\u003c\/sup\u003eC]Methionine ([\u003csup\u003e11\u003c\/sup\u003eC]MET) 199\u003cbr\u003e\u003ci\u003eAmy L. Vāvere and Scott E. Snyder\u003c\/i\u003e\u003c\/p\u003e \u003cp\u003e21. Synthesis of (+)-\u003ci\u003eα\u003c\/i\u003e-[\u003csup\u003e11\u003c\/sup\u003eC]Dihydrotetrabenazine ([\u003csup\u003e11\u003c\/sup\u003eC]DTBZ) 213\u003cbr\u003e\u003ci\u003eMichael R. Kilbourn\u003c\/i\u003e\u003c\/p\u003e \u003cp\u003e22. Synthesis of [\u003csup\u003e11\u003c\/sup\u003eC]Flumazenil([\u003csup\u003e11\u003c\/sup\u003eC]FMZ) 221\u003cbr\u003e\u003ci\u003eRoberto Canales-Candela, Patrick J. Riss, and Franklin I. Aigbirhio\u003c\/i\u003e\u003c\/p\u003e \u003cp\u003e23. Synthesis of [\u003csup\u003e11\u003c\/sup\u003eC]Hexadecanoic Acid ([\u003csup\u003e11\u003c\/sup\u003eC]Palmitic Acid) 233\u003cbr\u003e\u003ci\u003eAdam C. Runkle, Xia Shao, and Peter J. H. Scott\u003c\/i\u003e\u003c\/p\u003e \u003cp\u003e24. Synthesis of \u003ci\u003eO\u003c\/i\u003e-methyl-\u003csup\u003e11\u003c\/sup\u003eC]Metomidate ([\u003csup\u003e11\u003c\/sup\u003eC]-MTO) 245\u003cbr\u003e\u003ci\u003eIstván Boros and Franklin I. Aigbirhio\u003c\/i\u003e\u003c\/p\u003e \u003cp\u003e25. Synthesis of [\u003csup\u003e11\u003c\/sup\u003eC]Carfentanil ([\u003csup\u003e11\u003c\/sup\u003eC]CFN) 257\u003cbr\u003e\u003ci\u003eLouis Tluczek and Xia Shao\u003c\/i\u003e\u003c\/p\u003e \u003cp\u003e26. Synthesis of [carbonyl-\u003csup\u003e11\u003c\/sup\u003eC]Way-100635 265\u003cbr\u003e\u003ci\u003eJan D. Andersson, Sangram Nag, Raisa N. Krasikova, Victor W. Pike, and Christer Halldin\u003c\/i\u003e\u003c\/p\u003e \u003cp\u003e27. Synthesis of [\u003csup\u003e11\u003c\/sup\u003eC]Raclopride 275\u003cbr\u003e\u003ci\u003eXia Shao\u003c\/i\u003e\u003c\/p\u003e \u003cp\u003e28. Synthesis of 3-Amino-4-[2-(\u003ci\u003eN\u003c\/i\u003e-Methyl-\u003ci\u003eN\u003c\/i\u003e-[\u003csup\u003e11\u003c\/sup\u003eC]Methyl-Amino-Methyl)Phenylsulfanyl]-Benzonitrile ([\u003csup\u003e11\u003c\/sup\u003eC]Dasb) 285\u003cbr\u003e\u003ci\u003eDaniela Haeusler, Markus Mitterhauser, and Wolfgang Wadsak\u003c\/i\u003e\u003c\/p\u003e \u003cp\u003e29. Synthesis of [\u003csup\u003e11\u003c\/sup\u003eC] Acetate 297\u003cbr\u003e\u003ci\u003eFilippo Lodi, Claudio Malizia, and Stefano Boschi\u003c\/i\u003e\u003c\/p\u003e \u003cp\u003e30. Synthesis of \u003ci\u003eN\u003c\/i\u003e-(2-[\u003csup\u003e11\u003c\/sup\u003eC]Methoxybenzyl)-\u003ci\u003eN\u003c\/i\u003e-(4-Phenoxypyridin-3-yl)Acetamide ([\u003csup\u003e11\u003c\/sup\u003eC]PBR28) 305\u003cbr\u003e\u003ci\u003eQi-Huang Zheng, Min Wang, and Bruce H. Mock\u003c\/i\u003e\u003c\/p\u003e \u003cp\u003e\u003cb\u003ePart III Other Radiopharmaceuticals 313\u003c\/b\u003e\u003c\/p\u003e \u003cp\u003e31. Synthesis of [\u003csup\u003e13\u003c\/sup\u003eN]Ammonia ([\u003csup\u003e13\u003c\/sup\u003eN]NH\u003csub\u003e3\u003c\/sub\u003e) 315\u003cbr\u003e\u003ci\u003ePeter J. H. Scott\u003c\/i\u003e\u003c\/p\u003e \u003cp\u003e32. Synthesis of [\u003csup\u003e68\u003c\/sup\u003eGA]Gallium Dota-(TYR\u003csup\u003e3\u003c\/sup\u003e)-Octreotide Acetate ([\u003csup\u003e68\u003c\/sup\u003eGA]-Dotatoc) 321\u003cbr\u003e\u003ci\u003eHarald Eidherr, Friedrich Girschele, Markus Mitterhauser, and Wolfgang Wadsak\u003c\/i\u003e\u003c\/p\u003e \u003cp\u003eAppendix 1 Supplier Information 335\u003c\/p\u003e \u003cp\u003eIndex 339\u003c\/p\u003e  \u003cb\u003ePeter J. H. Scott\u003c\/b\u003e is an Assistant Professor in the Department of Radiology at the University of Michigan Medical School. Dr. Scott edited \u003ci\u003eLinker Strategies in Solid-phase Organic Synthesis\u003c\/i\u003e (also from Wiley) and is the series editor for the Wiley Series on \u003ci\u003eSolid Phase Organic Syntheses\u003c\/i\u003e.  \u003cp\u003e\u003cb\u003eBrian G. Hockley\u003c\/b\u003e is Radiopharmaceutical Quality Manager at the University of Michigan Medical School, where he works with Michael Kilbourn on radiopharmaceutical research and development. Mr. Hockley has co-authored several articles and a chapter in \u003ci\u003eLinker Strategies in Solid-phase Organic Synthesis\u003c\/i\u003e (also from Wiley).\u003c\/p\u003e  \u003cb\u003eThe ultimate reference guide to the synthesis of radiopharmaceuticals\u003c\/b\u003e  \u003cp\u003eThe \u003ci\u003eRadiochemical Syntheses\u003c\/i\u003e series provides scientists and professionals with a comprehensive reference to proven synthetic methods for radiochemical reactions, along with step-by-step guidance on how to replicate these syntheses in the laboratory.\u003c\/p\u003e \u003cp\u003eVolume 1 in the series focuses on the synthesis and purification of radiopharmaceuticals in clinical use today. It brings together in one complete, self-contained volume a collection of monographs containing a wealth of practical information from across the literature, demonstrating in meticulous detail how to prepare radiopharmaceuticals for positron emission tomography (PET) imaging, especially in tumor studies, cardiology, and neuroscience.\u003c\/p\u003e \u003cp\u003eReaders have key experimental details culled from the literature at their fingertips, greatly simplifying the process of qualifying a site for the clinical production of new radiopharmaceuticals.\u003c\/p\u003e","brand":"Wiley","offers":[{"title":"Default Title","offer_id":47989910077669,"sku":"NP9780470588956","price":153.95,"currency_code":"USD","in_stock":false}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/1842\/7735\/files\/9780470588956.jpg?v=1761785871","url":"https:\/\/k12savings.com\/es\/products\/radiopharmaceuticals-for-positron-emission-tomography-volume-1-isbn-9780470588956","provider":"K12savings","version":"1.0","type":"link"}