{"product_id":"principles-of-stem-cell-biology-and-cancer-isbn-9781118670620","title":"Principles of Stem Cell Biology and Cancer","description":"Principles of Stem Cell Biology and Cancer: Future Applications and Therapeutics Tarik Regad, The John van Geest Cancer Research Centre, Nottingham Trent University, UK, Thomas J. Sayers, Centre for Cancer Research, National Cancer Institute, Frederick, USA and Robert Rees The John van Geest Cancer Research Centre, Nottingham Trent University, UK The field of cancer stem cells is expanding rapidly, with many groups focusing on isolating and identifying cancer stem cell populations. Although some progress has been made developing efficient cancer therapies, targeting cancer stem cells remains one of the important challenges facing the growing stem cell research community. Principles of Stem Cell Biology and Cancer brings together original contributions from international experts in the field to present the very latest information linking stem cell biology and cancer. Divided into two parts, the book begins with a detailed introduction to stem cell biology with a focus on the characterization of these cells, progress that has been made in their identification, as well as future therapeutic applications of stem cells. The second part focuses on cancer stem cells and their role in cancer development, progression and chemo-resistance. This section of the book includes an overview of recent progress concerning therapies targeting cancer stem cells. Features: An authoritative introduction to the link between stem cell biology and cancer. Includes contributions from leading international experts in the field. Well-illustrated with full colour figures throughout. This book will prove an invaluable resource for basic and applied researchers and clinicians working on the development of new cancer treatments and therapies, providing a timely publication of high quality reviews outlining the current progress and exciting future possibilities for stem cell research.  \u003cp\u003eList of Contributors vii\u003c\/p\u003e \u003cp\u003ePreface xiii\u003c\/p\u003e \u003cp\u003e\u003cb\u003ePart I Stem Cells 1\u003c\/b\u003e\u003c\/p\u003e \u003cp\u003e1 Isolation and Characterization of Human Embryonic Stem Cells and Future Applications in Tissue Engineering Therapies 3\u003cbr\u003e \u003ci\u003eChristian Unger, James Hackland, David Preskey and Harry Moore\u003c\/i\u003e\u003c\/p\u003e \u003cp\u003e2 Epigenetics, Stem Cell Pluripotency and Differentiation 27\u003cbr\u003e \u003ci\u003eMaria J. Barrero\u003c\/i\u003e\u003c\/p\u003e \u003cp\u003e3 Stem Cell Niche and Microenvironment 45\u003cbr\u003e \u003ci\u003eMarcio Alvarez-Silva\u003c\/i\u003e\u003c\/p\u003e \u003cp\u003e4 Haematopoietic Stem Cells in Therapy 65\u003cbr\u003e \u003ci\u003eJos Domen and Jignesh Dalal\u003c\/i\u003e\u003c\/p\u003e \u003cp\u003e5 Isolation and Identification of Neural Stem\/Progenitor Cells 85\u003cbr\u003e \u003ci\u003eLoic P. Deleyrolle and Brent A. Reynolds\u003c\/i\u003e\u003c\/p\u003e \u003cp\u003e\u003cb\u003ePart II Cancer Stem Cells 101\u003c\/b\u003e\u003c\/p\u003e \u003cp\u003e6 The Role of Epithelial–Mesenchymal Transition in Cancer Metastasis 103\u003cbr\u003e \u003ci\u003ePaul C. McDonald and Shoukat Dedhar\u003c\/i\u003e\u003c\/p\u003e \u003cp\u003e7 Regulation of Breast Cancer Stem Cells by Mesenchymal Stem Cells in the Metastatic Niche 123\u003cbr\u003e \u003ci\u003eFayaz Malik, Hasan Korkaya, Shawn G. Clouthier and Max S. Wicha\u003c\/i\u003e\u003c\/p\u003e \u003cp\u003e8 Isolation and Identification of Neural Cancer Stem\/Progenitor Cells 145\u003cbr\u003e \u003ci\u003eDavid Bakhshinyan, Maleeha Qazi, Neha Garg, Chitra Venugopal,\u003c\/i\u003e\u003c\/p\u003e \u003cp\u003e9 Colon Stem Cells in Colorectal Cancer 169\u003cbr\u003e \u003ci\u003eVarun V. Prabhu, Wafik S. El-Deiry and Niklas Finnberg\u003c\/i\u003e\u003c\/p\u003e \u003cp\u003e10 Prostate Cancer and Prostate Cancer Stem Cells 193\u003cbr\u003e \u003ci\u003eMagdalena E. Buczek, Jerome C. Edwards and Tarik Regad\u003c\/i\u003e\u003c\/p\u003e \u003cp\u003e11 Stem Cells and Pancreatic Cancer 213\u003cbr\u003e \u003ci\u003eAudrey M. Hendley and Jennifer M. Bailey\u003c\/i\u003e\u003c\/p\u003e \u003cp\u003e12 NANOG in Cancer Development 231\u003cbr\u003e \u003ci\u003eBigang Liu and Dean G. Tang\u003c\/i\u003e\u003c\/p\u003e \u003cp\u003e13 Liver Cancer Stem Cells and Hepatocarcinogenesis 253\u003cbr\u003e \u003ci\u003eHirohisa Okabe, Hiromitsu Hayashi, Takatsugu Ishimoto, Kosuke Mima, Shigeki Nakagawa, Hideyuki Kuroki, Katsunori Imai, Hidetoshi Nitta, Daisuke Hashimoto, Akira Chikamoto, Takatoshi Ishiko, Toru Beppu and Hideo Baba\u003c\/i\u003e\u003c\/p\u003e \u003cp\u003e14 Basic Science of Liver Cancer Stem Cells and Hepatocarcinogenesis 273\u003cbr\u003e \u003ci\u003eKatherine S. Koch and Hyam L. Leffert\u003c\/i\u003e\u003c\/p\u003e \u003cp\u003e15 Cancer Stem Cell Biomarkers 305\u003cbr\u003e \u003ci\u003eStefano Zapperi and Caterina A.M. La Porta\u003c\/i\u003e\u003c\/p\u003e \u003cp\u003e16 Interatomic Analysis of the Stem Cell Marker NANOG in a Prostate Cancer Setting 317\u003cbr\u003e \u003ci\u003eKiran Mall and Graham Ball\u003c\/i\u003e\u003c\/p\u003e \u003cp\u003eIndex 353\u003c\/p\u003e \u003cb\u003eTarik Regad\u003c\/b\u003e, \u003ci\u003eThe John van Geest Cancer Research Centre, Nottingham Trent University, Nottingham, UK\u003c\/i\u003e\u003cbr\u003e\u003cbr\u003e\u003cb\u003eThomas J. Sayers\u003c\/b\u003e, \u003ci\u003eLeidos Biomedical Research Inc., and the Cancer and Infl ammation Program,\u003c\/i\u003e\u003cbr\u003e\u003ci\u003eFrederick National Laboratory for Cancer Research, Frederick, MD, USA\u003c\/i\u003e\u003cbr\u003e\u003cbr\u003e\u003cb\u003eRobert C. Rees\u003c\/b\u003e, \u003ci\u003eThe John van Geest Cancer Research Centre, Nottingham Trent University,\u003c\/i\u003e\u003cbr\u003e\u003ci\u003eNottingham, UK\u003c\/i\u003e Principles of Stem Cell Biology and Cancer: Future Applications and Therapeutics Tarik Regad, The John van Geest Cancer Research Centre, Nottingham Trent University, UK, Thomas J. Sayers, Centre for Cancer Research, National Cancer Institute, Frederick, USA and Robert Rees The John van Geest Cancer Research Centre, Nottingham Trent University, UK The field of cancer stem cells is expanding rapidly, with many groups focusing on isolating and identifying cancer stem cell populations. Although some progress has been made developing efficient cancer therapies, targeting cancer stem cells remains one of the important challenges facing the growing stem cell research community. Principles of Stem Cell Biology and Cancer brings together original contributions from international experts in the field to present the very latest information linking stem cell biology and cancer. Divided into two parts, the book begins with a detailed introduction to stem cell biology with a focus on the characterization of these cells, progress that has been made in their identification, as well as future therapeutic applications of stem cells. The second part focuses on cancer stem cells and their role in cancer development, progression and chemo-resistance. This section of the book includes an overview of recent progress concerning therapies targeting cancer stem cells. Features: An authoritative introduction to the link between stem cell biology and cancer. Includes contributions from leading international experts in the field. Well-illustrated with full colour figures throughout. This book will prove an invaluable resource for basic and applied researchers and clinicians working on the development of new cancer treatments and therapies, providing a timely publication of high quality reviews outlining the current progress and exciting future possibilities for stem cell research.","brand":"Wiley-Blackwell","offers":[{"title":"Default Title","offer_id":47989854535909,"sku":"NP9781118670620","price":139.95,"currency_code":"USD","in_stock":false}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/1842\/7735\/files\/9781118670620.jpg?v=1761785685","url":"https:\/\/k12savings.com\/es\/products\/principles-of-stem-cell-biology-and-cancer-isbn-9781118670620","provider":"K12savings","version":"1.0","type":"link"}