{"product_id":"polymeric-chiral-catalyst-design-and-chiral-polymer-synthesis-isbn-9780470568200","title":"Polymeric Chiral Catalyst Design and Chiral Polymer Synthesis","description":"This book reviews chiral polymer synthesis and its application to asymmetric catalysis. It features the design and use of polymer-immobilized catalysts and methods for their design and synthesis. Chapters cover peptide-catalyzed and enantioselective synthesis, optically-active polymers, and continuous flow processes. It collects recent advances in an important field of polymer and organic chemistry, with leading researchers explaining applications in academic and industry R \u0026amp; D.  PREFACE xiii  \u003cp\u003eFOREWORD xvii\u003c\/p\u003e \u003cp\u003eCONTRIBUTORS xix\u003c\/p\u003e \u003cp\u003e\u003cb\u003e1 An Overview of Polymer-Immobilized Chiral Catalysts and Synthetic Chiral Polymers 1\u003c\/b\u003e\u003cbr\u003e \u003ci\u003eShinichi Itsuno\u003c\/i\u003e\u003c\/p\u003e \u003cp\u003e1.1 Introduction \/ 1\u003c\/p\u003e \u003cp\u003e1.2 Polymeric Chiral Catalyst \/ 2\u003c\/p\u003e \u003cp\u003e1.3 Synthesis of Optically Active Polymers \/ 8\u003c\/p\u003e \u003cp\u003e\u003cb\u003e2 Polymer-Immobilized Chiral Organocatalyst 17\u003c\/b\u003e\u003cbr\u003e \u003ci\u003eNaoki Haraguchi and Shinichi Itsuno\u003c\/i\u003e\u003c\/p\u003e \u003cp\u003e2.1 Introduction \/ 17\u003c\/p\u003e \u003cp\u003e2.2 Synthesis of Polymer-immobilized Chiral Organocatalyst \/ 18\u003c\/p\u003e \u003cp\u003e2.3 Polymer-immobilized Cinchona Alkaloids \/ 22\u003c\/p\u003e \u003cp\u003e2.4 Other Polymer-immobilized Chiral Basic Organocatalysts \/ 27\u003c\/p\u003e \u003cp\u003e2.5 Polymer-immobilized Cinchona Alkaloid Quaternary Ammonium Salts \/ 28\u003c\/p\u003e \u003cp\u003e2.6 Polymer-immobilized MacMillan Catalysts \/ 35\u003c\/p\u003e \u003cp\u003e2.7 Polymer-immobilized Pyrrolidine Derivatives \/ 42\u003c\/p\u003e \u003cp\u003e2.8 Other Polymer-immobilized Chiral Quaternary Ammonium Salts \/ 46\u003c\/p\u003e \u003cp\u003e2.9 Polymer-immobilized Proline Derivatives \/ 46\u003c\/p\u003e \u003cp\u003e2.10 Polymer-immobilized Peptides and Poly(amino acid)s \/ 50\u003c\/p\u003e \u003cp\u003e2.11 Polymer-immobilized Chiral Acidic Organocatalysts \/ 50\u003c\/p\u003e \u003cp\u003e2.12 Helical Polymers as Chiral Organocatalysts \/ 51\u003c\/p\u003e \u003cp\u003e2.13 Cascade Reactions Using Polymer-immobilized Chiral Organocatalysts \/ 52\u003c\/p\u003e \u003cp\u003e2.14 Conclusions \/ 54\u003c\/p\u003e \u003cp\u003e\u003cb\u003e3 Asymmetric Synthesis Using Polymer-Immobilized Proline Derivatives 63\u003c\/b\u003e\u003cbr\u003e \u003ci\u003eMichelangelo Gruttadauria, Francesco Giacalone, and Renato Noto\u003c\/i\u003e\u003c\/p\u003e \u003cp\u003e3.1 Introduction \/ 63\u003c\/p\u003e \u003cp\u003e3.2 Polymer-supported Proline \/ 66\u003c\/p\u003e \u003cp\u003e3.3 Polymer-supported Prolinamides \/ 73\u003c\/p\u003e \u003cp\u003e3.4 Polymer-supported Proline-Peptides \/ 75\u003c\/p\u003e \u003cp\u003e3.5 Polymer-supported Pyrrolidines \/ 78\u003c\/p\u003e \u003cp\u003e3.6 Polymer-supported Prolinol and Diarylprolinol Derivatives \/ 80\u003c\/p\u003e \u003cp\u003e3.7 Conclusions and Outlooks \/ 84\u003c\/p\u003e \u003cp\u003e\u003cb\u003e4 Peptide-Catalyzed Asymmetric Synthesis 91\u003c\/b\u003e\u003cbr\u003e \u003ci\u003eKazuaki Kudo and Kengo Akagawa\u003c\/i\u003e\u003c\/p\u003e \u003cp\u003e4.1 Introduction \/ 91\u003c\/p\u003e \u003cp\u003e4.2 Poly(amino acid) Catalysts \/ 94\u003c\/p\u003e \u003cp\u003e4.3 Tri- and Tetrapeptide Catalysts \/ 99\u003c\/p\u003e \u003cp\u003e4.4 Longer Peptides with a Secondary Structure \/ 110\u003c\/p\u003e \u003cp\u003e4.5 Others \/ 118\u003c\/p\u003e \u003cp\u003e4.6 Conclusions and Outlooks \/ 119\u003c\/p\u003e \u003cp\u003e\u003cb\u003e5 Continuous Flow System using Polymer-Supported Chiral Catalysts 125\u003c\/b\u003e\u003cbr\u003e \u003ci\u003eSantiago V. Luis and Eduardo Garcıa-Verdugo\u003c\/i\u003e\u003c\/p\u003e \u003cp\u003e5.1 Introduction \/ 125\u003c\/p\u003e \u003cp\u003e5.2 Asymmetric Polymer-supported, Metal-based Catalysts and Reagents \/ 132\u003c\/p\u003e \u003cp\u003e5.3 Polymer-supported Asymmetric Organocatalysts \/ 147\u003c\/p\u003e \u003cp\u003e5.4 Polymer-supported Biocatalysts \/ 151\u003c\/p\u003e \u003cp\u003e5.5 Conclusions \/ 152\u003c\/p\u003e \u003cp\u003e\u003cb\u003e6 Chiral Synthesis on Polymer Support: A Combinatorial Approach 157\u003c\/b\u003e\u003cbr\u003e \u003ci\u003eDeepak B. Salunke and Chung-Ming Sun\u003c\/i\u003e\u003c\/p\u003e \u003cp\u003e6.1 Introduction \/ 157\u003c\/p\u003e \u003cp\u003e6.2 Chiral Synthesis of Complex Polyfunctional Molecules on Polymer Support \/ 160\u003c\/p\u003e \u003cp\u003e6.3 Conclusions \/ 194\u003c\/p\u003e \u003cp\u003e\u003cb\u003e7 Synthesis and Application of Helical Polymers with Macromolecular Helicity Memory 201\u003c\/b\u003e\u003cbr\u003e \u003ci\u003eHiroki Iida and Eiji Yashima\u003c\/i\u003e\u003cbr\u003e \u003c\/p\u003e \u003cp\u003e7.1 Introduction \/ 201\u003c\/p\u003e \u003cp\u003e7.2 Macromolecular Helicity Memory \/ 203\u003c\/p\u003e \u003cp\u003e7.3 Enantioselective Reaction Assisted by Helical Polymers with Helicity Memory \/ 218\u003c\/p\u003e \u003cp\u003e7.4 Conclusions \/ 219\u003c\/p\u003e \u003cp\u003e\u003cb\u003e8 Poly(isocyanide)s, Poly(quinoxaline-2,3-diyl)s, and Related Helical Polymers Used as Chiral Polymer Catalysts in Asymmetric Synthesis 223\u003c\/b\u003e\u003cbr\u003e \u003ci\u003eYuuya Nagata and Michinori Suginome\u003c\/i\u003e\u003c\/p\u003e \u003cp\u003e8.1 Introduction \/ 223\u003c\/p\u003e \u003cp\u003e8.2 Asymmetric Synthesis of Poly(isocyanide)s \/ 224\u003c\/p\u003e \u003cp\u003e8.3 Asymmetric Synthesis of Poly(quinoxaline)s \/ 244\u003c\/p\u003e \u003cp\u003e8.4 Enantioselective Catalysis using Helical Polymers \/ 255\u003c\/p\u003e \u003cp\u003e8.5 Conclusions \/ 262\u003c\/p\u003e \u003cp\u003e\u003cb\u003e9\u003c\/b\u003e \u003cb\u003eC2\u003c\/b\u003e \u003cb\u003eChiral Biaryl Unit-Based Helical Polymers and Their Application to Asymmetric Catalysis 267\u003c\/b\u003e\u003cbr\u003e \u003ci\u003eTakeshi Maeda and Toshikazu Takata\u003c\/i\u003e\u003c\/p\u003e \u003cp\u003e9.1 Introduction \/ 267\u003c\/p\u003e \u003cp\u003e9.2 Synthesis of C2 Chiral Unit-based Helical Polymers \/ 269\u003c\/p\u003e \u003cp\u003e9.3 Asymmetric Reactions Catalyzed by Helical Polymer Catalysts \/ 282\u003c\/p\u003e \u003cp\u003e9.4 Conclusions \/ 289\u003c\/p\u003e \u003cp\u003e\u003cb\u003e10 Immobilization of Multicomponent Asymmetric Catalysts (MACs) 293\u003c\/b\u003e\u003cbr\u003e \u003ci\u003eHiroaki Sasai and Shinobu Takizawa\u003c\/i\u003e\u003c\/p\u003e \u003cp\u003e10.1 Introduction \/ 293\u003c\/p\u003e \u003cp\u003e10.2 Dendrimer-Supported and Dendronized Polymer-supported MACs \/ 294\u003c\/p\u003e \u003cp\u003e10.3 Nanoparticles as Supports for Chiral Catalysts [13] \/ 302\u003c\/p\u003e \u003cp\u003e10.4 The Catalyst Analog Approach [24] \/ 311\u003c\/p\u003e \u003cp\u003e10.5 Metal-bridged Polymers as Heterogeneous Catalysts: An Immobilization Method for MACs Without Using Any Support [26] \/ 314\u003c\/p\u003e \u003cp\u003e10.6 Conclusion \/ 318\u003c\/p\u003e \u003cp\u003e\u003cb\u003e11 Optically Active Polymer and Dendrimer Synthesis and Their Use in Asymmetric Synthesis 323\u003c\/b\u003e\u003cbr\u003e \u003ci\u003eQiao-Sheng Hu and Lin Pu\u003c\/i\u003e\u003c\/p\u003e \u003cp\u003e11.1 Introduction \/ 323\u003c\/p\u003e \u003cp\u003e11.2 Synthesis and Application of BINOL\/BINAP-based Optically Active Polymers \/ 324\u003c\/p\u003e \u003cp\u003e11.3 Synthesis and Application of Optically Active Dendrimers \/ 355\u003c\/p\u003e \u003cp\u003e11.4 Conclusions \/ 360\u003c\/p\u003e \u003cp\u003e\u003cb\u003e12 Asymmetric Polymerizations of\u003c\/b\u003e \u003cb\u003eN\u003c\/b\u003e\u003cb\u003e-Substituted Maleimides 365\u003c\/b\u003e\u003cbr\u003e \u003ci\u003eKenjiro Onimura and Tsutomu Oishi\u003c\/i\u003e\u003c\/p\u003e \u003cp\u003e12.1 Introduction \/ 365\u003c\/p\u003e \u003cp\u003e12.2 Chirality of 1-Mono- or 1,1-Disubstituted and 1,2-Disubstituted Olefins \/ 365\u003c\/p\u003e \u003cp\u003e12.3 Asymmetric Polymerizations of Achiral N-Substituted Maleimides \/ 368\u003c\/p\u003e \u003cp\u003e12.4 Anionic Polymerization Mechanism of RMI \/ 371\u003c\/p\u003e \u003cp\u003e12.5 Asymmetric Polymerizations of Chiral N-Substituted Maleimides \/ 372\u003c\/p\u003e \u003cp\u003e12.6 Structure and Absolute Stereochemistry of Poly(RMI) \/ 373\u003c\/p\u003e \u003cp\u003e12.7 Asymmetric Radical Polymerizations ofN-Substituted Maleimides \/ 378\u003c\/p\u003e \u003cp\u003e12.8 Chiral Discrimination Using Poly(RMI) \/ 378\u003c\/p\u003e \u003cp\u003e12.9 Conclusions \/ 384\u003c\/p\u003e \u003cp\u003e\u003cb\u003e13 Synthesis of Hyperbranched Polymer Having Binaphthol Units via Oxidative Cross-Coupling Polymerization 389\u003c\/b\u003e\u003cbr\u003e \u003ci\u003eShigeki Habaue\u003c\/i\u003e\u003c\/p\u003e \u003cp\u003e13.1 Introduction \/ 389\u003c\/p\u003e \u003cp\u003e13.2 Oxidative Cross-coupling Reaction between 2-Naphthol and 3-Hydroxy-2-naphthoate \/ 391\u003c\/p\u003e \u003cp\u003e13.3 Oxidative Cross-coupling Polymerization Affording Linear Poly(binaphthol) \/ 392\u003c\/p\u003e \u003cp\u003e13.4 Oxidative Cross-coupling Polymerization Leading to a Hyperbranched Polymer \/ 396\u003c\/p\u003e \u003cp\u003e13.5 Photoluminescence Properties of Hyperbranched Polymers \/ 400\u003c\/p\u003e \u003cp\u003e13.6 Conclusions \/ 403\u003c\/p\u003e \u003cp\u003e\u003cb\u003e14 Optically Active Polyketones 407\u003c\/b\u003e\u003cbr\u003e \u003ci\u003eKyoko Nozaki\u003c\/i\u003e\u003c\/p\u003e \u003cp\u003e14.1 Introduction \/ 407\u003c\/p\u003e \u003cp\u003e14.2 Asymmetric Synthesis of Isotactic Poly(propylene-alt-co) \/ 409\u003c\/p\u003e \u003cp\u003e14.3 Asymmetric Synthesis of Isotactic Syndiotactic Poly(styrene-alt-co) \/ 411\u003c\/p\u003e \u003cp\u003e14.4 Asymmetric Terpolymers Consisting of Two Kinds of Olefins and Carbon Monoxide \/ 413\u003c\/p\u003e \u003cp\u003e14.5 Asymmetric Polymerization of Other Olefins with CO \/ 414\u003c\/p\u003e \u003cp\u003e14.6 Chemical Transformations of Optically Active Polyketones \/ 415\u003c\/p\u003e \u003cp\u003e14.7 Conformational Studies on the Optically Active Polyketones \/ 416\u003c\/p\u003e \u003cp\u003e14.8 Conclusions \/ 419\u003c\/p\u003e \u003cp\u003e\u003cb\u003e15 Synthesis and Function of Chiral\u003c\/b\u003e \u003cb\u003ep\u003c\/b\u003e\u003cb\u003e-Conjugated Polymers from Phenylacetylenes 423\u003c\/b\u003e\u003cbr\u003e \u003ci\u003eToshiki Aoki, Takashi Kaneko, and Masahiro Teraguchi\u003c\/i\u003e\u003c\/p\u003e \u003cp\u003e15.1 Introduction \/ 423\u003c\/p\u003e \u003cp\u003e15.2 Helix-sense-selective Polymerization (HSSP) of Substituted Phenylacetylenes and Function of the Resulting One-handed Helical Poly(phenylacetylene)s \/ 425\u003c\/p\u003e \u003cp\u003e15.3 Chiral Desubstitution of Side Groups in Membrane State \/ 439\u003c\/p\u003e \u003cp\u003e15.4 Synthesis of Chiral Polyradicals \/ 446\u003cbr\u003e \u003c\/p\u003e \u003cp\u003e\u003cb\u003e16 P-Stereogenic Oligomers, Polymers, and Related Cyclic Compounds 457\u003c\/b\u003e\u003cbr\u003e \u003ci\u003eYasuhiro Morisaki and Yoshiki Chujo\u003c\/i\u003e\u003c\/p\u003e \u003cp\u003e16.1 Introduction \/ 457\u003c\/p\u003e \u003cp\u003e16.2 P-Stereogenic Oligomers Containing Chiral \"P\" Atoms in the Main Chain \/ 458\u003c\/p\u003e \u003cp\u003e16.3 P-Stereogenic Polymers Containing Chiral \"P\" Atoms in the Main Chain \/ 470\u003c\/p\u003e \u003cp\u003e16.4 Cyclic Phosphines Using P-Stereogenic Oligomers as Building Blocks \/ 475\u003c\/p\u003e \u003cp\u003e16.5 Conclusions \/ 485\u003c\/p\u003e \u003cp\u003e\u003cb\u003eINDEX 489\u003c\/b\u003e\u003c\/p\u003e \u003cb\u003eShinichi Itsuno, PhD\u003c\/b\u003e, is a Professor at Toyohashi University of Technology. His research focuses on the interface between organic chemistry and polymer chemistry, and is especially concerned with asymmetric synthesis, reactive polymers, and new polymer synthesis. Dr. Itsuno has written over a hundred papers, as well as thirty book chapters.  \u003cp\u003eGet to grips with chiral polymer synthesis and its application to asymmetric catalysis\u003c\/p\u003e \u003cp\u003eWritten and edited by leading experts from around the world, Polymeric Chiral Catalyst Design and Chiral Polymer Synthesis is the first book to bring together in a coherent and cohesive form the history and latest research on chiral polymers.\u003c\/p\u003e \u003cp\u003eBecause they can be easily separated from a reaction mixture and reused, repeatedly, polymer-immobilized chiral catalysts have received considerable attention in recent years, making the book a particularly timely contribution to the literature on the subject.\u003c\/p\u003e \u003cp\u003eCovering polymer-immobilized catalysts, the design of polymer-immobilized asymmetric catalysts, the synthetic aspects of chiral polymers, and dendrimers, the book includes chapters on peptide-catalyzed and enantioselective synthesis,optically-active polymers, continuous flow processes, and much more.\u003c\/p\u003e \u003cp\u003eWith up-to-the-minute explanations of potential applications in academic and industry R\u0026amp;D, Polymeric Chiral Catalyst Design and Chiral Polymer Synthesis is an absolute must-have resource. Not only is it suitable for use as an introductory text for students, it also provides a much-needed one-stop handbook for professionals interested in the chemistry, properties, and applications of chiral polymers.\u003c\/p\u003e","brand":"Wiley","offers":[{"title":"Default Title","offer_id":47989812330725,"sku":"NP9780470568200","price":185.95,"currency_code":"USD","in_stock":false}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/1842\/7735\/files\/9780470568200.jpg?v=1761785550","url":"https:\/\/k12savings.com\/es\/products\/polymeric-chiral-catalyst-design-and-chiral-polymer-synthesis-isbn-9780470568200","provider":"K12savings","version":"1.0","type":"link"}