{"product_id":"plant-bioactives-and-drug-discovery-isbn-9780470582268","title":"Plant Bioactives and Drug Discovery","description":"\u003cp\u003e\u003cb\u003eAn in-depth exploration of the applications of plant bioactive metabolites in drug research and development\u003c\/b\u003e\u003c\/p\u003e \u003cp\u003eHighlighting the complexity and applications of plant bioactive metabolites in organic and medicinal chemistry, \u003ci\u003ePlant Bioactives and Drug Discovery: Principles, Practice, and Perspectives\u003c\/i\u003e provides an in-depth overview of the ways in which plants can inform drug research and development. An edited volume featuring multidisciplinary international contributions from acclaimed scientists researching bioactive natural products, the book provides an incisive overview of one of the most important topics in pharmaceutical studies today.\u003c\/p\u003e \u003cp\u003eWith coverage of strategic methods of natural compound isolation, structural manipulation, natural products in clinical trials, quality control, and more, and featuring case studies on medicinal plants, the book serves as a definitive guide to the field of plant biodiversity as it relates to medicine. In addition, chapters on using natural products as drugs that target specific disease areas, including neurological disorders, inflammation, infectious diseases, and cancer, illustrate the myriad possibilities for therapeutic applications.\u003c\/p\u003e \u003cp\u003eWide ranging and comprehensive, \u003ci\u003ePlant Bioactives and Drug Discovery\u003c\/i\u003e also includes important information on marketing, regulations, intellectual property rights, and academic-industry collaboration as they relate to plant-based drug research, making it an essential resource for advanced students and academic and industry professionals working in biochemical, pharmaceutical, and related fields.\u003c\/p\u003e \u003cp\u003eContributors xv\u003c\/p\u003e \u003cp\u003ePreface xix\u003c\/p\u003e \u003cp\u003e1 Natural Products in Drug Discovery: Recent Advances 1\u003cbr\u003e\u003ci\u003eGordon M. Cragg, Paul G. Grothaus, and David J. Newman\u003c\/i\u003e\u003c\/p\u003e \u003cp\u003e2 Modern Approaches in the Search for New Active Compounds from Crude Extracts of Natural Sources 43\u003cbr\u003e\u003ci\u003eEmerson F. Queiroz, Kurt Hostettmann, and Jean-Luc Wolfender\u003c\/i\u003e\u003c\/p\u003e \u003cp\u003e3 Natural Products as Lead Compounds in Medicinal Chemistry 81\u003cbr\u003e\u003ci\u003eEliezer J. Barreiro, Carlos A. M. Fraga, and Lidia M. Lima\u003c\/i\u003e\u003c\/p\u003e \u003cp\u003e4 The Importance of Structural Manipulation of Natural Compounds in Drug Discovery and Development 127\u003cbr\u003e\u003ci\u003eArturo San Feliciano, Mar\u003c\/i\u003e\u003ci\u003eía \u003c\/i\u003e\u003ci\u003eÁ. Castro, Jos\u003c\/i\u003e\u003ci\u003eé L. L\u003c\/i\u003e\u003ci\u003eópez-P\u003c\/i\u003e\u003ci\u003eérez, and Esther del Olmo\u003c\/i\u003e\u003c\/p\u003e \u003cp\u003e5 The Action of Plants and their Constituents on the Central Nervous System 161\u003cbr\u003e\u003ci\u003eF\u003c\/i\u003e\u003ci\u003eúlvio R. Mendes, Giuseppina Negri, Joaquim M. Duarte-Almeida, Ricardo Tabach, and Elisaldo A. Carlini\u003c\/i\u003e\u003c\/p\u003e \u003cp\u003e6 The Role of Natural Products in Discovery of New Anti-Infective Agents with Emphasis on Antifungal Compounds 205\u003cbr\u003e\u003ci\u003eMaximiliano Sortino, Marcos Derita, Laura Svetaz, Marcela Raimondi, Melina Di Liberto, Elisa Petenatti, Mahabir Gupta, and Susana Zacchino\u003c\/i\u003e\u003c\/p\u003e \u003cp\u003e7 Antiulcer Agents from Higher Plants 241\u003cbr\u003e\u003ci\u003eLuiz C. Klein-J\u003c\/i\u003e\u003ci\u003eúnior, Jos\u003c\/i\u003e\u003ci\u003eé R. Santin, and S\u003c\/i\u003e\u003ci\u003eérgio F. de Andrade\u003c\/i\u003e\u003c\/p\u003e \u003cp\u003e8 Recent Progress in the Chemistry and Biology of Paclitaxel (Taxol\u003csup\u003eTM\u003c\/sup\u003e) and Related Taxanes 263\u003cbr\u003e\u003ci\u003eJun Qi, Jielu Zhao, and David G. I. Kingston\u003c\/i\u003e\u003c\/p\u003e \u003cp\u003e9 Cancer Chemopreventive Activity of Higher Plants 337\u003cbr\u003e\u003ci\u003eA. Douglas Kinghorn, Yulin Ren, Jie Li, and Chung Ki Sung\u003c\/i\u003e\u003c\/p\u003e \u003cp\u003e10 Medicinal Plants and Pharmaceutical Technology 359\u003cbr\u003e\u003ci\u003eRuth M. Lucinda da Silva, Ang\u003c\/i\u003e\u003ci\u003eélica G. Couto, and Tania M.B. Bresolin\u003c\/i\u003e\u003c\/p\u003e \u003cp\u003e11 Natural Products in Clinical Trials 395\u003cbr\u003e\u003ci\u003eSigrun Chrubasik\u003c\/i\u003e\u003c\/p\u003e \u003cp\u003e12 The Influence of Biotic and Abiotic Factors on the Production of Secondary Metabolites in Medicinal Plants 419\u003cbr\u003e\u003ci\u003eDayana R. Gouvea, Leonardo Gobbo-Neto, and Norberto P. Lopes\u003c\/i\u003e\u003c\/p\u003e \u003cp\u003e13 Production of Bioactives Compounds: The Importance of Pictet–Spengler Reaction in the XXI Century 453\u003cbr\u003e\u003ci\u003ePilar Menendez, Ilaria D’Acquarica, Giuliano Delle Monache, Francesca Ghirga, Andrea Calcaterra, Marco Barba, Alberto Macone, Alberto Boffi, Alessandra Bonamore, and Bruno Botta\u003c\/i\u003e\u003c\/p\u003e \u003cp\u003e14 Screening Methods for Drug Discovery from Plants 489\u003cbr\u003e\u003ci\u003eAlan L. Harvey\u003c\/i\u003e\u003c\/p\u003e \u003cp\u003e15 Phytotherapeutics – Intellectual Property Rights, Global Market, and Global Regulatory Guidelines 499\u003cbr\u003e\u003ci\u003eJames D. McChesney, Raymond Cooper, and Kip Vought\u003c\/i\u003e\u003c\/p\u003e \u003cp\u003e16 Cooperation Between the Pharmaceutical Industry and Academic Institutions in Drug Discovery 529\u003cbr\u003e\u003ci\u003eValdir Cechinel-Filho, Rivaldo Niero, and Rosendo A. Yunes\u003c\/i\u003e\u003c\/p\u003e \u003cp\u003eAcknowledgments 542\u003c\/p\u003e \u003cp\u003eReferences 542\u003c\/p\u003e \u003cp\u003eIndex 545\u003c\/p\u003e  \u003cp\u003e“In conclusion, this book could be a useful guide not only for PhD students starting their activity in the field of plant metabolites, but also for more advanced researchers looking for a state-of-the-art overview of modern research in this fascinating field.”  (\u003ci\u003eChemMedChem\u003c\/i\u003e, 1 March 2013)\u003c\/p\u003e  \u003cp\u003e\u003cb\u003eValdir Cechinel-Filho, PhD\u003c\/b\u003e, is Professor and Researcher at the Chemical-Pharmaceutical Investigations Center, University of Vale do Itajaí in Brazil. The editor of five books, seventeen contributed chapters, and over 250 scientific papers and reviews, Dr. Filho is also Associate Editor of \u003ci\u003ePharmaceutical Biology\u003c\/i\u003e, a member of the editorial boards of several journals, and a reviewer for many journals, including \u003ci\u003eEuropean Journal of Medicinal Chemistry\u003c\/i\u003e, \u003ci\u003eJournal of Pharmacy and Pharmacology\u003c\/i\u003e, \u003ci\u003eNatural Product Research\u003c\/i\u003e, \u003ci\u003ePlanta Medica\u003c\/i\u003e, and \u003ci\u003eJournal of Agricultural and Food Chemistry\u003c\/i\u003e.\u003c\/p\u003e \u003cp\u003e\u003cb\u003eAn in-depth exploration of the applications of plant bioactive metabolites in drug research and development\u003c\/b\u003e\u003c\/p\u003e \u003cp\u003eHighlighting the complexity and applications of plant bioactive metabolites in organic and medicinal chemistry, \u003ci\u003ePlant Bioactives and Drug Discovery: Principles, Practice, and Perspectives\u003c\/i\u003e provides an in-depth overview of the ways in which plants can inform drug research and development. An edited volume featuring multidisciplinary international contributions from acclaimed scientists researching bioactive natural products, the book provides an incisive overview of one of the most important topics in pharmaceutical studies today.\u003c\/p\u003e \u003cp\u003eWith coverage of strategic methods of natural compound isolation, structural manipulation, natural products in clinical trials, quality control, and more, and featuring case studies on medicinal plants, the book serves as a definitive guide to the field of plant biodiversity as it relates to medicine. In addition, chapters on using natural products as drugs that target specific disease areas, including neurological disorders, inflammation, infectious diseases, and cancer, illustrate the myriad possibilities for therapeutic applications.\u003c\/p\u003e \u003cp\u003eWide ranging and comprehensive, \u003ci\u003ePlant Bioactives and Drug Discovery\u003c\/i\u003e also includes important information on marketing, regulations, intellectual property rights, and academic-industry collaboration as they relate to plant-based drug research, making it an essential resource for advanced students and academic and industry professionals working in biochemical, pharmaceutical, and related fields.\u003c\/p\u003e","brand":"Wiley","offers":[{"title":"Default Title","offer_id":47989796339941,"sku":"NP9780470582268","price":216.95,"currency_code":"USD","in_stock":false}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/1842\/7735\/files\/9780470582268.jpg?v=1761785500","url":"https:\/\/k12savings.com\/es\/products\/plant-bioactives-and-drug-discovery-isbn-9780470582268","provider":"K12savings","version":"1.0","type":"link"}