{"product_id":"neuronal-and-cognitive-effects-of-oestrogens-isbn-9780471492030","title":"Neuronal and Cognitive Effects of Oestrogens","description":"Although normally thought of as a sex hormone, recent research has highlighted the numerous and significant effects that oestrogen has on the CNS, extending far beyond its important reproductive role. It has been shown that oestrogen acts as a neural growth factor with important influences on the survival, plasticity, regeneration and ageing of the mammalian brain.\u003cbr\u003e \u003cbr\u003e This exciting book brings together leading clinicians and researchers to discuss oestrogen's basic mechanisms of action, the extrahypothalmic brain regions it affects, and its influence on cognitive functions in animals and humans. Finally, recent research on the role of oestrogens in ageing and dementia, including the significance of oestrogen action in Alzheimer's disease, is discussed. The 15 papers contained in this book, together with the extensive discussion sessions that follow them, reveal much new and exciting work in this area, and identify promising new research directions.Dieser Band gehört zur renommierten Reihe \"Novartis Foundation Series\". Er gibt einen Überblick über die jüngsten Erkenntnisse der neuronalen Wirkungen von Östrogenen. Diskutiert werden die Grundmechanismen der Östrogenwirkung, die extra-hypothalmischen Gehirnsysteme, die von Östrogenen beeinflußt werden sowie Östrogene in Verbindung mit ihrer kognitiven Funktion und ihrer Rolle bei der Neuroprotektion. Enthalten sind Beiträge international führender Experten auf diesem Gebiet, die das Thema anhand aktuellster Forschungsergebnisse umfassend behandeln. (y05\/00)  Chairman's Introduction (B. McEwen).  \u003cp\u003eMechanism of Oestrogen Signalling with Particular Reference to the Role of ERß in the Central Nervous System (E. Treuter, \u003ci\u003eet al.\u003c\/i\u003e).\u003c\/p\u003e \u003cp\u003eOestrogen Receptor Function at Classical and Alternative Response Elements (P. Kushner, \u003ci\u003eet al.\u003c\/i\u003e).\u003c\/p\u003e \u003cp\u003eGENERAL DISCUSSION I.\u003c\/p\u003e \u003cp\u003eNuclear Receptor Versus Plasma Membrane Oestrogen Receptor (E. Levin).\u003c\/p\u003e \u003cp\u003eNovel Sites and Mechanisms of Oestrogen Action in the Brain (C. Toran-Allerand).\u003c\/p\u003e \u003cp\u003eOestrogen Modulation of Noradrenaline Neurotransmission (A. Herbison, \u003ci\u003eet al.\u003c\/i\u003e).\u003c\/p\u003e \u003cp\u003eOestrogen and the Cholinergic Hypothesis: Implications for Oestrogen Replacement Therapy in Postmenopausal Women (R. Gibbs).\u003c\/p\u003e \u003cp\u003eOvarian Steroid Action in the Serotonin Neural System of Macaques (C. Bethea, \u003ci\u003eet al.\u003c\/i\u003e).\u003c\/p\u003e \u003cp\u003eOestrogen Effects on Dopaminergic Function in Striatum (J. Becker).\u003c\/p\u003e \u003cp\u003eGENERAL DISCUSSION II.\u003c\/p\u003e \u003cp\u003eOestrogen Effects in Olivo-Cerebellar and Hippocampal Circuits (S. Smith, \u003ci\u003eet al.\u003c\/i\u003e).\u003c\/p\u003e \u003cp\u003eEffects of Oestradiol on Hippocampal Circuitry (C. Woolley).\u003c\/p\u003e \u003cp\u003eOestrogen and Cognitive Function Throughout the Female Lifespan (B. Sherwin).\u003c\/p\u003e \u003cp\u003eNeuroprotective Effects of Phenolic A Ring Oestrogens (P. Green, \u003ci\u003eet al.\u003c\/i\u003e).\u003c\/p\u003e \u003cp\u003eThe Female Sex Hormone Oestrogen as Neuroprotectant: Activities at Various Levels (C. Behl, \u003ci\u003eet al.\u003c\/i\u003e).\u003c\/p\u003e \u003cp\u003eNeurohormonal Signalling Pathways and the Regulation of Alzheimer ß-Amyloid Metabolism (S. Gandy \u0026amp; S. Petanceska).\u003c\/p\u003e \u003cp\u003eOestrogens and Dementia (V. Henderson).\u003c\/p\u003e \u003cp\u003eIndexes.\u003c\/p\u003e  \u003cp\u003e\"The text is an excellent summary of what is new on estrogens in the brain and will be of interest to neuroscience departments....\" (\u003cem\u003eJournal of the Neurological Sciences,\u003c\/em\u003e March 2001  \u003c\/p\u003e\u003cp\u003e\u003cb\u003eDerek J. Chadwick\u003c\/b\u003e and \u003cb\u003eJamie A. Goode\u003c\/b\u003e are editors for \u003ci\u003eNeuronal and Cognitive Effects of Oestrogens\u003c\/i\u003e and other scientific titles.\u003c\/p\u003e  Although normally thought of as a sex hormone, recent research has highlighted the numerous and significant effects that oestrogen has on the CNS, extending far beyond its important reproductive role. It has been shown that oestrogen acts as a neural growth factor with important influences on the survival, plasticity, regeneration and ageing of the mammalian brain.  \u003cp\u003eThis exciting book brings together leading clinicians and researchers to discuss oestrogen's basic mechanisms of action, the extrahypothalmic brain regions it affects, and its influence on cognitive functions in animals and humans. Finally, recent research on the role of oestrogens in ageing and dementia, including the significance of oestrogen action in Alzheimer's disease, is discussed. The 15 papers contained in this book, together with the extensive discussion sessions that follow them, reveal much new and exciting work in this area, and identify promising new research directions.\u003c\/p\u003e","brand":"Wiley","offers":[{"title":"Default Title","offer_id":47989684240613,"sku":"NP9780471492030","price":211.95,"currency_code":"USD","in_stock":false}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/1842\/7735\/files\/9780471492030.jpg?v=1761785092","url":"https:\/\/k12savings.com\/es\/products\/neuronal-and-cognitive-effects-of-oestrogens-isbn-9780471492030","provider":"K12savings","version":"1.0","type":"link"}