{"product_id":"neural-transplantation-in-neurodegenerative-disease-isbn-9780471492467","title":"Neural Transplantation in Neurodegenerative Disease","description":"The field of neural transplantation is at a crucial stage in its development, with results of important clinical trials on transplantation in patients with Parkinson's disease expected soon and novel, alternative approaches to fetal transplantation being actively investigated. This timely book brings together leading neuroscientists, clinicians, and cell and developmenta; biologists to discuss the use of neural transplants in neurodegenerative diseases such as Parkinson's disease, Huntington's disease, amyotrophic lateral sclerosis, multiple sclerosis and spinal cord injury. There is also extensive coverage of the potential alternatives to freshly derived fetal tissue as the source of transplants, such as xenografts, encapsulated cells and immortalized stem cells. With authoritative contributions and lively discussion sections, this book draws together much new and exciting work in this field, and identifies promising new research directions.Ein internationales, interdisziplinäres Autorenteam diskutiert in diesem Buch Tiermodelle und klinische Anwendungen der Nerventransplantation. Angesprochen werden hochaktuelle Themen wie die Parkinsonsche Krankheit, die Hippocampus-Amnesie und der Einsatz von fetalem Gewebe zur Gewinnung von Transplantaten. Struktur und Funktionsweise von Gehirn und Rückenmark werden ausführlich erläutert. (06\/00) Introduction (J. Gray).\u003cbr\u003e \u003cbr\u003e Cell Replacement Strategies for Neurodegenerative Disorders (A. Björklund).\u003cbr\u003e \u003cbr\u003e Functional Analysis of Fronto-Striatal Reconstruction by Striatal Grafts (S. Dunnett).\u003cbr\u003e \u003cbr\u003e Functional Reconstruction of the Hippocampus: Fetal Versus Conditionally Immortal Neuroepithelial Stem Cell Grafts (H. Hodges, et al.).\u003cbr\u003e \u003cbr\u003e Gene Transfer for Neuroprotection in Animal Models of Parkinson's Disease and Amyotrophic Lateral Sclerosis (M. Bohn, et al.).\u003cbr\u003e \u003cbr\u003e Repair of Corticospinal Axons by Transplantation of Olfactory Ensheathing Cells (G. Raisman).\u003cbr\u003e \u003cbr\u003e Neural Transplantation in Parkinson's Disease (O. Lindvall).\u003cbr\u003e \u003cbr\u003e Transplantation of Human Fetal Striatal Tissue in Huntington's Disease: Rationale for Clinical Studies (T. Freeman, et al.).\u003cbr\u003e \u003cbr\u003e GENERAL DISCUSSION I: PROSPECTS FOR FETAL TRANSPLANTS.\u003cbr\u003e \u003cbr\u003e Neurotransplantation in Neurodegenerative Disease: A Survey of Relevant Issues in Developmental Neurobiology (J. Price, et al.).\u003cbr\u003e \u003cbr\u003e Molecular and Cellular Mechanisms in Immune Rejection of Intracerebral Neural Transplants (T. Brevig, et al.).\u003cbr\u003e \u003cbr\u003e Porcine Neural Xenografts: What are the Issues? (R. Barker).\u003cbr\u003e \u003cbr\u003e Gene Transfer Techniques for the Delivery of GDNF in Parkinson's Disease (J.-L. Ridet, et al.).\u003cbr\u003e \u003cbr\u003e Neurogenesis in the Adult Hippocampus (G. Kempermann \u0026amp; F. Gage).\u003cbr\u003e \u003cbr\u003e Neural Stem Cells are Uniquely Suited for Cell Replacement and Gene Therapy in the CNS (V. Ourednik, et al.).\u003cbr\u003e \u003cbr\u003e Functional Repair with Neural Stem Cells (J. Sinden, et al.).\u003cbr\u003e \u003cbr\u003e Remyelinating the Demyelinated CNS (W. Blakemore, et al.).\u003cbr\u003e \u003cbr\u003e GENERAL DISCUSSION II: THE ES CELL APPROACH.\u003cbr\u003e \u003cbr\u003e FINAL DISCUSSION: THE FUTURE FOR FETAL GRAFTS;\u003cbr\u003e STEM CELL STRATEGIES.\u003cbr\u003e \u003cbr\u003e Index of Contributors.\u003cbr\u003e \u003cbr\u003e Subject Index. \"...well written with clear illustrations in many cases and extensively referenced...\" (British Journal of Neurosurgery, Vol.16, No.6, 2002) \u003cp\u003e\u003cb\u003eDerek J. Chadwick\u003c\/b\u003e and \u003cb\u003eJamie A. Goode\u003c\/b\u003e are editors for \u003ci\u003eNeural Transplantation in Neurodegenerative Disease: Current Status and New Directions\u003c\/i\u003e and other scientific titles.\u003c\/p\u003e The field of neural transplantation is at a crucial stage in its development, with results of important clinical trials on transplantation in patients with Parkinson's disease expected soon and novel, alternative approaches to fetal transplantation being actively investigated. This timely book brings together leading neuroscientists, clinicians, and cell and developmenta; biologists to discuss the use of neural transplants in neurodegenerative diseases such as Parkinson's disease, Huntington's disease, amyotrophic lateral sclerosis, multiple sclerosis and spinal cord injury. There is also extensive coverage of the potential alternatives to freshly derived fetal tissue as the source of transplants, such as xenografts, encapsulated cells and immortalized stem cells. With authoritative contributions and lively discussion sections, this book draws together much new and exciting work in this field, and identifies promising new research directions.","brand":"Wiley","offers":[{"title":"Default Title","offer_id":47989682405605,"sku":"NP9780471492467","price":211.95,"currency_code":"USD","in_stock":false}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/1842\/7735\/files\/9780471492467.jpg?v=1761785087","url":"https:\/\/k12savings.com\/es\/products\/neural-transplantation-in-neurodegenerative-disease-isbn-9780471492467","provider":"K12savings","version":"1.0","type":"link"}