{"product_id":"neglected-tropical-diseases-and-phytochemicals-in-drug-discovery-isbn-9781119616603","title":"Neglected Tropical Diseases and Phytochemicals in Drug Discovery","description":"\u003cb\u003eNEGLECTED TROPICAL DISEASES AND PHYTOCHEMICALS IN DRUG DISCOVERY\u003c\/b\u003e \u003cp\u003e\u003cb\u003eExplore novel drug discovery updates from medicinal plants to help fight the devastating effects of neglected tropical diseases\u003c\/b\u003e \u003c\/p\u003e\u003cp\u003e\u003ci\u003eNeglected Tropical Diseases and Phytochemicals in Drug Discovery\u003c\/i\u003e delivers a comprehensive exploration of the drug discovery process as it pertains to neglected tropical diseases. The book covers recent advancements in drug discovery, as well as druggable targets and new challenges facing the industry. It offers readers expansive discussions of specific diseases, including protozoan, helminth, bacterial, viral, fungal, and ectoparasitic infections. \u003c\/p\u003e\u003cp\u003eThis book provides readers with insightful perspectives from leading industry voices on fifty years of trends and progress in the search for new, safe, and affordable therapeutic drugs in the fight against neglected tropical diseases. It includes information beneficial to researchers in a variety of fields of biology, chemistry, medicine, and pharmaceuticals. \u003c\/p\u003e\u003cp\u003eThe distinguished authors cover topics including the effects of phytochemicals on the causative agent of leprosy and the potential applicability of phytochemicals in the management of Dengue fever. Readers will also enjoy the inclusion of: \u003c\/p\u003e\u003cul\u003e\n\u003cli\u003eThorough introductions to neglected tropical diseases, phytochemicals, protein targets, and mechanisms in drug discovery, as well as the epidemiology of neglected tropical diseases\u003c\/li\u003e \u003cli\u003eAn exploration of novel bioactive lead compounds for drug discovery against neglected tropical diseases, leishmaniasis, lymphatic filariasis, trypanosomiasis, and schistosomiasis\u003c\/li\u003e \u003cli\u003eDiscussions of protozoan infections, including herbal, nutritional, and traditional remedies for giardiasis and the anti-leishmanial potentials of phytochemicals\u003c\/li\u003e \u003cli\u003eExaminations of helminth infections, including the prospects of phytochemicals in the treatment of helminthiasis\u003c\/li\u003e\n\u003c\/ul\u003e \u003cp\u003ePerfect for medicinal chemists, drug developers, and research and development scientists, \u003ci\u003eNeglected Tropical Diseases and Phytochemicals in Drug Discovery\u003c\/i\u003e will also earn a place in the libraries of toxicologists and researchers in biology, chemistry, medicinal chemistry, ethnobotany, and bioinformatics seeking a one-stop resource for drug discovery for neglected tropical diseases. \u003c\/p\u003e\u003cp\u003eList of Contributors xxi\u003c\/p\u003e \u003cp\u003ePreface xxvii\u003c\/p\u003e \u003cp\u003e\u003cb\u003ePart I Introduction to Neglected Tropical Diseases 1\u003c\/b\u003e\u003c\/p\u003e \u003cp\u003e1 Epidemiology of Neglected Tropical Diseases 3\u003ci\u003e\u003cbr\u003e Kurubaran Ganasegeran and Surajudeen Abiola Abdulrahman\u003c\/i\u003e\u003c\/p\u003e \u003cp\u003e2 Neglected Tropical Diseases, Phytochemicals, Protein Targets,and Mechanisms in Drug Discovery 37\u003cbr\u003e \u003ci\u003eLalit R. Samant, Tehseen M. Dhorajiwala, and Sumit T. Haldar\u003c\/i\u003e\u003c\/p\u003e \u003cp\u003e3 Novel Bioactive Lead Compounds for Drug Discovery Against NeglectedTropical Diseases, Leishmaniasis, Lymphatic Filariasis, Trypanosomiasis(African Sleeping Sickness and Chagas Disease),\u003cbr\u003e and Schistosomiasis 75\u003cbr\u003e \u003ci\u003eAbeer M. El Sayed and Chukwuebuka Egbuna\u003c\/i\u003e\u003c\/p\u003e \u003cp\u003e\u003cb\u003ePart II Protozoan Infections 135\u003c\/b\u003e\u003c\/p\u003e \u003cp\u003e4 Herbal, Nutritional, and Traditional Remedies for Giardiasis:Phytochemicals as Drug Candidates 137\u003cbr\u003e \u003ci\u003eSamrat Bhattacharyya\u003c\/i\u003e\u003c\/p\u003e \u003cp\u003e5 Antiprotozoal Activity of Phytochemicals Against \u003ci\u003eEntamoeba histolytica\u003c\/i\u003e, the Causative Agent of Amoebiasis 171\u003cbr\u003e \u003ci\u003eGoutam Kumar Jena, Chinam Niranjan Patra, and Jnyanaranjan Panda\u003c\/i\u003e\u003c\/p\u003e \u003cp\u003e6 Antileishmanial Potentials of Phytochemicals 183\u003ci\u003e\u003cbr\u003e Shahira M. Ezzat, Mohamed A. Salem, and Ahmed Zayed\u003c\/i\u003e\u003c\/p\u003e \u003cp\u003e\u003cb\u003ePart III Helminth Infections 199\u003c\/b\u003e\u003c\/p\u003e \u003cp\u003e7 Prospects of Phytochemicals for the Treatment of Helminthiasis 201\u003ci\u003e\u003cbr\u003e Muhammad Akram, Charles Oluwaseun Adetunji, Ejaz Mohiuddin, Tolulope Olawumi Oladosun, Phebean Ozolua, Frances N. Olisaka, Chukwuebuka Egbuna, Olugbenga Samuel Micheal, Juliana Bunmi Adetunji, Leena Hameed, Chinaza Godswill Awuchi, Kingsley C. Patrick-Iwuanyanwu, and Olugbemi Tope Olaniyan\u003c\/i\u003e\u003c\/p\u003e \u003cp\u003e8 Efficacy of Phytochemicals of Medicinal Plants for the Treatment of Human Echinococcosis: Echinococcal Disease, Hydatidosis, or Hydatid Disease Drug Discovery 225\u003cbr\u003e \u003ci\u003eCharles Oluwaseun Adetunji, Chukwuebuka Egbuna, Tolulope Olawumi\u003c\/i\u003e \u003ci\u003eOladosun, Muhammad Akram, Olugbenga Samuel Micheal, Frances\u003c\/i\u003e \u003ci\u003eN. Olisaka, Phebean Ozolua, Juliana Bunmi Adetunji, Goddidit Esiro\u003c\/i\u003e \u003ci\u003eEnoyoze, and Olugbemi Tope Olaniyan\u003c\/i\u003e\u003c\/p\u003e \u003cp\u003e9 Filaricidal Activity of Phytochemicals Against Lymphatic Filariasis 245\u003ci\u003e\u003cbr\u003e Jayashree V. Hanchinalmath, Darcia D’mello, Kirankumar Shivasharanappa, T. Pramod, and Sharangouda J. Patil\u003c\/i\u003e\u003c\/p\u003e \u003cp\u003e10 Dracunculiasis (Guinea Worm Disease) and Phytochemicals in Drug Discovery 271\u003cbr\u003e \u003ci\u003eMuhammad Akram, Chukwuebuka Egbuna, Mehwish Iqbal, Zarrin Basharat, Mithun Rudrapal, Kingsley C. Patrick-Iwuanyanwu, Johra Khan, and Chukwuemelie Zedech Uche\u003c\/i\u003e\u003c\/p\u003e \u003cp\u003e11 Medicinal Potentials of Phytochemicals as a Source of Drugs for the Treatment of Onchocerciasis (River Blindness) 283\u003cbr\u003e \u003ci\u003eChandrashekar Srinivasa, Chandan Shivamallu, S. R. Santhosh Kumar, P. Sushma, Shiva Prasad Kollur, Seema J. Patel, S. S. Patil, R. Suhas, Chukwuebuka Egbuna, and Bui Thanh Tung\u003c\/i\u003e\u003c\/p\u003e \u003cp\u003e12 Foodborne Trematodiases and Phytochemicals 299\u003ci\u003e\u003cbr\u003e Shashank M. Patil, Ramith Ramu, Prithvi S. Shirahatti, and K. Sumana\u003c\/i\u003e\u003c\/p\u003e \u003cp\u003e\u003cb\u003ePart IV Bacterial Infections 337\u003c\/b\u003e\u003c\/p\u003e \u003cp\u003e13 Bacteriocidal Effects of Phytochemicals on \u003ci\u003eMycobacterium ulcerans\u003c\/i\u003e, the Causative Agents of Buruli Ulcer 339\u003cbr\u003e \u003ci\u003eAlloysius Chibuike Ogodo, Francis Ushie Ebuara, and Chidera Favour Ogodo\u003c\/i\u003e\u003c\/p\u003e \u003cp\u003e14 Bactericidal Effects of Phytochemicals on \u003ci\u003eMycobacterium leprae\u003c\/i\u003e, the Causative Agent of Leprosy 359\u003cbr\u003e \u003ci\u003eChukwuebuka Egbuna, Muhammad Akram, Surajudeen Abiola\u003c\/i\u003e \u003ci\u003eAbdulrahman, Andrew G. Mtewa, Mithun Rudrapal, Kingsley C. Patrick-Iwuanyanwu,\u003c\/i\u003e \u003ci\u003eSaher Rahat, Iram Ghaffar, Amna Siddique, Jonathan\u003c\/i\u003e \u003ci\u003eChinenye Ifemeje, Michael C. Olisah, Mihnea-Alexandru\u003c\/i\u003e \u003ci\u003eGa˘man, Bui Thanh\u003c\/i\u003e \u003ci\u003eTung, Chandan Shivamallu, Chukwuemelie Zedech Uche, and Johra Khan\u003c\/i\u003e\u003c\/p\u003e \u003cp\u003e15 Medicinal Plants and Phytochemicals Effective Against Chlamydia trachomatis, the Causative Agent of Trachoma 381\u003ci\u003e\u003cbr\u003e Yusuf Abubakar, Chukwuebuka Egbuna, Ahmed Olatunde, Habibu Tijjani, and Uchenna Estella Odoh\u003c\/i\u003e\u003c\/p\u003e \u003cp\u003e16 Yaws (Endemic Treponematoses) Drug Discovery from Phytochemicals: An Informatics Protocol for Drug Target Identification to Phytochemical Inhibitor Screening and Validation 397\u003cbr\u003e \u003ci\u003eZarrin Basharat and Arisha Khoso\u003c\/i\u003e\u003c\/p\u003e \u003cp\u003e\u003cb\u003ePart V Viral Infections 417\u003c\/b\u003e\u003c\/p\u003e \u003cp\u003e17 Dengue Fever: A Brief Overview and Insights into the Potential Applicability of Phytochemicals in Its Management 419\u003cbr\u003e \u003ci\u003eMuhammad Akram, Charles Oluwaseun Adetunji, Chukwuebuka Egbuna,\u003c\/i\u003e \u003ci\u003eShaista Jabeen, Olugbemi Tope Olaniyan, Nebechi Jane Ezeofor,\u003c\/i\u003e \u003ci\u003eOsikemekha Anthony Anani, Umme Laila, Mihnea-Alexandru Ga˘man, Kingsley C. Patrick-Iwuanyanwu, Jonathan Chinenye Ifemeje, Chukwudi Jude Chikwendu, Michael C. Olisah, and Mithun Rudrapal\u003c\/i\u003e\u003c\/p\u003e \u003cp\u003e18 Medicinal Potentials of Phytochemicals for the Management of Rabies 441\u003cbr\u003e \u003ci\u003eD. Chandan, Shiva Prasad Kollur, Shashanka K. Prasad, Chandrashekar\u003c\/i\u003e \u003ci\u003eSrinivasa, Prabhurajeshwar, S. M. Gopinath, Chukwuebuka Egbuna, and\u003c\/i\u003e \u003ci\u003eChandan Shivamallu\u003c\/i\u003e\u003c\/p\u003e \u003cp\u003e\u003cb\u003ePart VI Fungal and Ectoparasitic Infections 453\u003c\/b\u003e\u003c\/p\u003e \u003cp\u003e19 Roles of Medicinal Plants in the Diagnosis and Treatment of Eumycetoma 455\u003cbr\u003e \u003ci\u003eChinaza Godswill Awuchi, Muhammad Akram, and Chibueze Gospel Awuchi\u003c\/i\u003e\u003c\/p\u003e \u003cp\u003e20 Role of Phytochemicals in the Treatment of Ectoparasitic Infections: Scabies and Myiasis 477\u003cbr\u003e \u003ci\u003eSantwana Palai, Shyam Sundar Kesh, Chinaza Godswill Awuchi,\u003c\/i\u003e \u003ci\u003eSurajudeen Abiola Abdulrahman, and Chukwuebuka Egbuna\u003c\/i\u003e\u003c\/p\u003e \u003cp\u003e\u003cb\u003ePart VII Non Classified NTDs: Malaria and Human Tuberculosis 499\u003c\/b\u003e\u003c\/p\u003e \u003cp\u003e21 Malaria and Recent Developments in Antimalarial Drugs 501\u003ci\u003e\u003cbr\u003e Mithun Rudrapal and Dipak Chetia\u003c\/i\u003e\u003c\/p\u003e \u003cp\u003e22 Therapeutic Potentials of Phytochemicals Against Mycobacterium tuberculosis, the Causative Agent of Tuberculosis 543\u003cbr\u003e \u003ci\u003eAlloysius Chibuike Ogodo, Verwiyeh Silas Tatah, Francis Ushie Ebuara,\u003c\/i\u003e \u003ci\u003eand Chidera Favour Ogodo\u003c\/i\u003e\u003c\/p\u003e \u003cp\u003eIndex 571 \u003c\/p\u003e \u003cp\u003e\u003cb\u003eChukwuebuka Egbuna\u003c\/b\u003e is a Research Biochemist in the Department of Biochemistry at Chukwuemeka Odumegwu Ojukwu University in Nigeria. He is a reviewer and editorial board member of several journals.\u003c\/p\u003e \u003cp\u003e\u003cb\u003e Muhammad Akram, PhD,\u003c\/b\u003e is Associate Professor in the Department of Eastern Medicine at the Government College University in Faisalabad, Pakistan. He has published numerous scholarly articles and is an editor and reviewer for several national and international journals. \u003c\/p\u003e\u003cp\u003e\u003cb\u003eJonathan Chinenye Ifemeje, PhD,\u003c\/b\u003e is Professor in the Department of Biochemistry at Chukwuemeka Odumegwu Ojukwu University in Nigeria. He is Managing Editor of the Tropical Journal of Applied Natural Sciences.  \u003c\/p\u003e\u003cp\u003e\u003cb\u003eExplore novel drug discovery updates from medicinal plants to help fight the devastating effects of neglected tropical diseases\u003c\/b\u003e\u003c\/p\u003e \u003cp\u003e\u003ci\u003eNeglected Tropical Diseases and Phytochemicals in Drug Discovery\u003c\/i\u003e delivers a comprehensive exploration of the drug discovery process as it pertains to neglected tropical diseases. The book covers recent advancements in drug discovery, as well as druggable targets and new challenges facing the industry. It offers readers expansive discussions of specific diseases, including protozoan, helminth, bacterial, viral, fungal, and ectoparasitic infections. \u003c\/p\u003e\u003cp\u003eThis book provides readers with insightful perspectives from leading industry voices on fifty years of trends and progress in the search for new, safe, and affordable therapeutic drugs in the fight against neglected tropical diseases. It includes information beneficial to researchers in a variety of fields of biology, chemistry, medicine, and pharmaceuticals. \u003c\/p\u003e\u003cp\u003eThe distinguished authors cover topics including the effects of phytochemicals on the causative agent of leprosy and the potential applicability of phytochemicals in the management of Dengue fever. Readers will also enjoy the inclusion of: \u003c\/p\u003e\u003cul\u003e\n\u003cli\u003eThorough introductions to neglected tropical diseases, phytochemicals, protein targets, and mechanisms in drug discovery, as well as the epidemiology of neglected tropical diseases\u003c\/li\u003e \u003cli\u003eAn exploration of novel bioactive lead compounds for drug discovery against neglected tropical diseases, leishmaniasis, lymphatic filariasis, trypanosomiasis, and schistosomiasis\u003c\/li\u003e \u003cli\u003eDiscussions of protozoan infections, including herbal, nutritional, and traditional remedies for giardiasis and the anti-leishmanial potentials of phytochemicals\u003c\/li\u003e \u003cli\u003eExaminations of helminth infections, including the prospects of phytochemicals in the treatment of helminthiasis\u003c\/li\u003e\n\u003c\/ul\u003e \u003cp\u003ePerfect for medicinal chemists, drug developers, and research and development scientists, \u003ci\u003eNeglected Tropical Diseases and Phytochemicals in Drug Discovery\u003c\/i\u003e will also earn a place in the libraries of toxicologists and researchers in biology, chemistry, medicinal chemistry, ethnobotany, and bioinformatics seeking a one-stop resource for drug discovery for neglected tropical diseases.\u003c\/p\u003e","brand":"Wiley","offers":[{"title":"Default Title","offer_id":47989679030501,"sku":"NP9781119616603","price":231.95,"currency_code":"USD","in_stock":false}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/1842\/7735\/files\/9781119616603.jpg?v=1761785074","url":"https:\/\/k12savings.com\/es\/products\/neglected-tropical-diseases-and-phytochemicals-in-drug-discovery-isbn-9781119616603","provider":"K12savings","version":"1.0","type":"link"}