{"product_id":"natural-products-in-chemical-biology-isbn-9781118101179","title":"Natural Products in Chemical Biology","description":"Based on the award winning \u003ci\u003eWiley Encyclopedia of Chemical Biology\u003c\/i\u003e, this book provides a general overview of the unique features of the small molecules referred to as \"natural products\", explores how this traditionally organic chemistry-based field was transformed by insights from genetics and biochemistry, and highlights some promising future directions. The book begins by introducing natural products from different origins, moves on to presenting and discussing biosynthesis of various classes of natural products, and then looks at natural products as models and the possibilities of using them in medicine. \u003cp\u003ePreface vii\u003c\/p\u003e \u003cp\u003eContributors ix\u003c\/p\u003e \u003cp\u003e\u003cb\u003ePart I Chemical Diversity of Natural Products 1\u003c\/b\u003e\u003c\/p\u003e \u003cp\u003e\u003cb\u003e1 Plant Natural Products 3\u003cbr\u003e \u003c\/b\u003e\u003ci\u003eA. Leslie Gunatilaka\u003c\/i\u003e\u003c\/p\u003e \u003cp\u003e\u003cb\u003e2 Marine Natural Products 31\u003cbr\u003e \u003c\/b\u003e\u003ci\u003eNobuhiro Fusetani\u003c\/i\u003e\u003c\/p\u003e \u003cp\u003e\u003cb\u003e3 Microbial Natural Products 65\u003cbr\u003e \u003c\/b\u003e\u003ci\u003eSergio Sanchez, Silvia Guzmán-Trampe, Mariana Ávalos, Beatriz Ruiz, Romina Rodríguez-Sanoja, and Manuel Jiménez-Estrada Copyrighted Material\u003c\/i\u003e\u003c\/p\u003e \u003cp\u003e\u003cb\u003ePart II Biosynthesis of Natural Products 109\u003c\/b\u003e\u003c\/p\u003e \u003cp\u003e\u003cb\u003e4 Nonribosomal Peptides 111\u003cbr\u003e \u003c\/b\u003e\u003ci\u003eGeorg Schoenafinger and Mohamed A. Marahiel\u003c\/i\u003e\u003c\/p\u003e \u003cp\u003e\u003cb\u003e5 Plant Terpenoids 127\u003cbr\u003e \u003c\/b\u003e\u003ci\u003eChristopher I. Keeling and Jörg Bohlmann\u003c\/i\u003e\u003c\/p\u003e \u003cp\u003e\u003cb\u003e6 Polyketides in Fungi 143\u003cbr\u003e \u003c\/b\u003e\u003ci\u003eThomas J. Simpson and Russell J. Cox\u003c\/i\u003e\u003c\/p\u003e \u003cp\u003e\u003cb\u003e7 Modular Polyketide Synthases 163\u003cbr\u003e \u003c\/b\u003e\u003ci\u003eTonia J. Buchholz, Jeffrey D. Kittendorf, and David H. Sherman\u003c\/i\u003e\u003c\/p\u003e \u003cp\u003e\u003cb\u003e8 Polyketide Polyethers 189\u003cbr\u003e \u003c\/b\u003e\u003ci\u003eAlison M. Hill\u003c\/i\u003e\u003c\/p\u003e \u003cp\u003e\u003cb\u003e9 Alkaloids 209\u003cbr\u003e \u003c\/b\u003e\u003ci\u003eSarah E. O’Connor\u003c\/i\u003e\u003c\/p\u003e \u003cp\u003e\u003cb\u003e10 Cofactors 239\u003cbr\u003e \u003c\/b\u003e\u003ci\u003eIlka Haase, Markus Fischer, Adelbert Bacher, Wolfgang Eisenreich, and Felix Rohdich\u003c\/i\u003e\u003c\/p\u003e \u003cp\u003e\u003cb\u003e11 Antibiotics 269\u003cbr\u003e \u003c\/b\u003e\u003ci\u003eSergey B. Zotchev\u003c\/i\u003e\u003c\/p\u003e \u003cp\u003e\u003cb\u003ePart III Natural Products in Medicine 287\u003c\/b\u003e\u003c\/p\u003e \u003cp\u003e\u003cb\u003e12 Pharmaceuticals: Natural Products and Natural Product Models 289\u003cbr\u003e \u003c\/b\u003e\u003ci\u003eSheo B. Singh\u003c\/i\u003e\u003c\/p\u003e \u003cp\u003e\u003cb\u003e13 Natural Products as Anticancer Agents 325\u003cbr\u003e \u003c\/b\u003e\u003ci\u003eDavidG.I.KingstonandDavidJ.Newman\u003c\/i\u003e\u003c\/p\u003e \u003cp\u003e\u003cb\u003e14 Plant-Derived Natural Products Research in Drug Discovery 351\u003cbr\u003e \u003c\/b\u003e\u003ci\u003eKuo-Hsiung Lee, Hideji Itokawa, Toshiyuki Akiyama, and Susan L. Morris-Natschke\u003c\/i\u003e\u003c\/p\u003e \u003cp\u003eIndex 389\u003c\/p\u003e  \u003cp\u003e“In summary, this is a really good book from a number of prominent research groups who have made important contributions to their fields.  Some chapters are well suited for newcomers to the subject, as well as for teaching or for reading by interested students.”  (\u003ci\u003eAngewandte Chemie International Edition\u003c\/i\u003e, 19 March 2014)\u003c\/p\u003e \u003cp\u003e \u003c\/p\u003e  \u003cp\u003e\u003cb\u003eNATANYA CIVJAN, PhD\u003c\/b\u003e, is a freelance editor with a doctorate in biochemistry. Formerly with John Wiley \u0026amp; Sons, she has developed and edited the \u003ci\u003eWiley Encyclopedia of Chemical Biology\u003c\/i\u003e and was part of the team responsible for the \u003ci\u003eWiley Interdisciplinary Reviews\u003c\/i\u003e, which won top prizes in publishing from the American Publishers Awards for Professional and Scholarly Excellence.\u003c\/p\u003e \u003cp\u003e\u003cb\u003eA timely and authoritative look at the chemistry of natural products\u003c\/b\u003e\u003c\/p\u003e \u003cp\u003eBased on the acclaimed \u003ci\u003eWiley Encyclopedia of Chemical Biology\u003c\/i\u003e, this book focuses on natural products and explores their impact on drug discovery and design. With emphasis on the gamut of biological diversity and activities of natural products, the book examines the unique features of these molecules, highlights influences from genetics and biochemistry, and points to promising future trends. Divided into three parts, \u003ci\u003eNatural Products in Chemical Biology\u003c\/i\u003e first introduces sources of natural products, then goes on to present the biosynthesis of main classes of natural products and their uses in medicine. The book presents fourteen self-contained, peer-reviewed articles carefully selected from the \u003ci\u003eWiley Encyclopedia of Chemical Biology\u003c\/i\u003e and new material. Clear, authoritative coverage includes:\u003c\/p\u003e \u003cul\u003e \u003cli\u003eA discussion of the chemical diversity of plant, marine, and microbial natural products\u003c\/li\u003e \u003cli\u003eBiosynthesis of nonribosomal peptides, plant terpenoids, polyketides, alkaloids, cofactors, and antibiotics\u003c\/li\u003e \u003cli\u003eUse of natural products and natural product models in the pharmaceutical industry\u003c\/li\u003e \u003c\/ul\u003e \u003cp\u003e\u003ci\u003eNatural Products in Chemical Biology\u003c\/i\u003e is an excellent introduction to the ongoing research in the chemistry of natural products for researchers in diverse fields, from organic and medicinal chemistry to molecular biology and the pharmaceutical industry.\u003c\/p\u003e","brand":"Wiley","offers":[{"title":"Default Title","offer_id":47989677228261,"sku":"NP9781118101179","price":153.95,"currency_code":"USD","in_stock":false}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/1842\/7735\/files\/9781118101179.jpg?v=1761785066","url":"https:\/\/k12savings.com\/es\/products\/natural-products-in-chemical-biology-isbn-9781118101179","provider":"K12savings","version":"1.0","type":"link"}