{"product_id":"natural-products-and-their-bioactives-in-antidiabetic-drug-discovery-isbn-9781119983316","title":"Natural Products and their Bioactives in Antidiabetic Drug Discovery","description":"Natural Products and their Bioactives in Antidiabetic Drug Discovery \u003cp\u003e\u003cb\u003eEnables researchers to effectively understand and use bioactive compounds to target, prevent, and manage diabetes\u003c\/b\u003e \u003c\/p\u003e\u003cp\u003e\u003ci\u003eNatural Products and Their Bioactives in Antidiabetic Drug Discovery \u003c\/i\u003eprovides readers with an overview of recent research in new drug discovery against diabetic complications based on bioactives from NPs, bridging the gap between the public research institutes and private companies working to find drugs to treat diabetes. To aid in reader comprehension, the text includes case studies and illustrated examples in relevant chapters. \u003c\/p\u003e\u003cp\u003ePart one presents chapters on fundamental concepts of diabetes mellitus (DM) and recent drug discovery progress along with the various druggable targets and challenges. Part two covers bioactive compounds targeting Type-1 Diabetes. Part three focuses on Type-2 Diabetes. In Part four, the contributors address gestational DM prevention and management with natural compounds. \u003c\/p\u003e\u003cp\u003eWritten by a global team of experts in the field, \u003ci\u003eNatural Products and their Bioactives in Antidiabetic Drug Discovery \u003c\/i\u003ecovers sample topics such as: \u003c\/p\u003e\u003cul\u003e\n\u003cli\u003eObesity risk factor in patients with T1DM and possible role of nutritional therapy in its management\u003c\/li\u003e \u003cli\u003eUse of natural non-insulin drugs as a novel approach to enhance therapeutic outcomes against T1DM\u003c\/li\u003e \u003cli\u003eEffectiveness of functional foods in intervening the diabetic complications and realistic results in clinical trials\u003c\/li\u003e \u003cli\u003eImplementation of nanotechnology in improving the bioavailability and reducing the threshold dose of bioactive compounds\u003c\/li\u003e \u003cli\u003eVarious antidiabetic mechanisms of action of different polyphenols and immunomodulatory role of NPs bioactives relevance in T1DM therapy\u003c\/li\u003e \u003cli\u003eEffects of natural products on genetics of gestational diabetes\u003c\/li\u003e\n\u003c\/ul\u003e \u003cp\u003eWith comprehensive coverage of recent research in new drug discovery against diabetic complications based on bioactives from NPs, \u003ci\u003eNatural Products and Their Bioactives in Antidiabetic Drug Discovery \u003c\/i\u003eis an essential resource for researchers and professionals involved in drug discovery and development, health care, medicinal chemistry, phytochemistry, plant science, and toxicology. \u003c\/p\u003e\u003cp\u003eList of Contributors viii\u003c\/p\u003e \u003cp\u003ePreface xii\u003c\/p\u003e \u003cp\u003e\u003cb\u003ePart I Fundamental Concepts of Diabetes Mellitus and Drug Discovery Process 1\u003c\/b\u003e\u003c\/p\u003e \u003cp\u003e1 Diabetes Mellitus and Natural Product-based Drug Discovery: Novel Directions 3\u003cbr\u003e \u003ci\u003eDavid J. Newman\u003c\/i\u003e\u003c\/p\u003e \u003cp\u003e2 Marine Natural Products in the Management of Diabetes Mellitus 18\u003cbr\u003e \u003ci\u003eMurali Krishna Paidi, Kanchan Siddaprasad Udata, and Subir Kumar Mandal\u003c\/i\u003e\u003c\/p\u003e \u003cp\u003e3 Carbohydrate-based Antidiabetic Agents from Natural Products 38\u003cbr\u003e \u003ci\u003eSandeep Singh\u003c\/i\u003e\u003c\/p\u003e \u003cp\u003e4 Functional Foods in Clinical Trials in the Intervention of Diabetes Complications 49\u003cbr\u003e \u003ci\u003eBavani Arumugam and Umah Rani Kuppusamy\u003c\/i\u003e\u003c\/p\u003e \u003cp\u003e5 Role of Nanotechnology in Refining the Antidiabetic Activities of Plant Derived Bioactives 74\u003cbr\u003e \u003ci\u003eSonam Mishra, Ravindra Dhar, Maitree Suttajit, and Bishnu Kumar Pandey\u003c\/i\u003e\u003c\/p\u003e \u003cp\u003e\u003cb\u003ePart II Bioactive Compounds Against Type 1 Diabetes Mellitus 97\u003c\/b\u003e\u003c\/p\u003e \u003cp\u003e6 Epidemiology and Genetics of Type 1 Diabetes Mellitus: The Effect of the Mediterranean Diet 99\u003cbr\u003e \u003ci\u003eBilge Nur Col and Muveddet Emel Alphan\u003c\/i\u003e\u003c\/p\u003e \u003cp\u003e7 The Emerging Role of Plant Polyphenols in the Management of Type 1 Diabetes Mellitus 113\u003cbr\u003e \u003ci\u003eS. Asha Devi, Suparna Mandal, and S. Raja Sekhar\u003c\/i\u003e\u003c\/p\u003e \u003cp\u003e8 Bioactives as Modulators of β-cells and Immunity in Therapy of Type 1 Diabetes Mellitus 136\u003cbr\u003e \u003ci\u003eShashank Kumar Ojha\u003c\/i\u003e\u003c\/p\u003e \u003cp\u003e9 Obesity in Type 1 Diabetes Mellitus: Clinical Impact and Nutritional Therapy 147\u003cbr\u003e \u003ci\u003eGülen Ecem Kalkan and Burcu Ateş Özcan\u003c\/i\u003e\u003c\/p\u003e \u003cp\u003e10 Protective Effects of Natural Non-insulin Drugs against Type 1 Diabetes Mellitus 164\u003cbr\u003e \u003ci\u003eWaseem Hassan, Faraza Javaid, Andleeb Shahzadi, and Sahar Bakht\u003c\/i\u003e\u003c\/p\u003e \u003cp\u003e\u003cb\u003ePart III Bioactive Compounds Against Type 2 Diabetes Mellitus 177\u003c\/b\u003e\u003c\/p\u003e \u003cp\u003e11 Age-induced Biomarkers of Oxidative Stress in Type 2 Diabetes Mellitus: Role of Plant Polyphenols 179\u003cbr\u003e \u003ci\u003eBrahm Kumar Tiwari and Kanti Bhooshan Pandey\u003c\/i\u003e\u003c\/p\u003e \u003cp\u003e12 Bioactives from Clove Oil for Antibacterial Wound Dressings for the Treatment and Management of Wounds in Type 2 Diabetes Mellitus 195\u003cbr\u003e \u003ci\u003eAndleeb Shahzadi and Haktan Sonmez\u003c\/i\u003e\u003c\/p\u003e \u003cp\u003e13 Nutritional Features and Bioactivities of Thymoquinone against Type 2 Diabetes Mellitus 211\u003cbr\u003e \u003ci\u003ePınar Atukeren\u003c\/i\u003e\u003c\/p\u003e \u003cp\u003e14 Effect of Resveratrol and Catechins in Maintaining Redox Homeostasis during Type 2 Diabetes Mellitus 219\u003cbr\u003e \u003ci\u003ePrachee Dubey and Geeta Watal\u003c\/i\u003e\u003c\/p\u003e \u003cp\u003e15 Cannabis: Action Mechanisms and Potential Roles in the Management of Type 2 Diabetes Mellitus 232\u003cbr\u003e \u003ci\u003eKarolin Yanar and Zeynep Mine Coşkun Yazıcı\u003c\/i\u003e\u003c\/p\u003e \u003cp\u003e\u003cb\u003ePart IV Gestational Diabetes: Prevention and Management by Natural Compounds 245\u003c\/b\u003e\u003c\/p\u003e \u003cp\u003e16 Epidemiology of Gestational Diabetes Mellitus: Preventive Significance of Dietary Pattern 247\u003cbr\u003e \u003ci\u003eBurcu Yeşilkaya\u003c\/i\u003e\u003c\/p\u003e \u003cp\u003e17 Biomarkers of Gestational Diabetes Mellitus, Dietary Polyphenols, and Drug Discovery 260\u003cbr\u003e \u003ci\u003eMansi Gandhi\u003c\/i\u003e\u003c\/p\u003e \u003cp\u003e18 Medicinal and Aromatic Plants in the Prevention of Gestational Diabetes and Associated Consequences: Current Insights 275\u003cbr\u003e \u003ci\u003eJigeesha Mishra, Kanti Bhooshan Pandey, and Shailendra Kumar Srivastava\u003c\/i\u003e\u003c\/p\u003e \u003cp\u003e19 Enhancement of Insulin Sensitivity and Management of Lipid Disorders during Gestational Diabetes Mellitus: Role of Capsaicin 294\u003cbr\u003e \u003ci\u003eBanu Orta-Yilmaz, Ahu Korkut, and Yasemin Aydin\u003c\/i\u003e\u003c\/p\u003e \u003cp\u003e20 Effects of Natural Products on the Genetics of Gestational Diabetes Mellitus 308\u003cbr\u003e \u003ci\u003eOnur Baykara\u003c\/i\u003e\u003c\/p\u003e \u003cp\u003eIndex 321\u003c\/p\u003e  \u003cp\u003e\u003cb\u003eKanti Bhooshan Pandey, PhD, \u003c\/b\u003eis a Senior Scientist and Assistant Professor in the Faculty of Biological Sciences, AcSIR; CSIR-Central Salt \u0026amp; Marine Chemicals Research Institute, Gujarat, India. \u003c\/p\u003e\u003cp\u003e\u003cb\u003eMaitree Suttajit, PhD, \u003c\/b\u003eis Professor Emeritus previously at School of Medicine, Chiang Mai University and later at School of Medical Sciences, University of Phayao, Thailand. \u003c\/p\u003e\u003cp\u003e\u003cb\u003ePinar Atukeren, PhD, \u003c\/b\u003eis a senior Professor in Medical Biochemistry teaching in İstanbul Üniversitesi-Cerrahpaşa, Cerrahpaşa Faculty of Medicine, Department of Medical Biochemistry, and also the Founding Dean of İstanbul Üniversitesi-Cerrahpaşa, Faculty of Pharmacy, Turkey.   \u003c\/p\u003e\u003cp\u003e\u003cb\u003eEnables researchers to effectively understand and use bioactive compounds to target, prevent, and manage diabetes\u003c\/b\u003e \u003c\/p\u003e\u003cp\u003e\u003ci\u003eNatural Products and Their Bioactives in Antidiabetic Drug Discovery \u003c\/i\u003eprovides readers with an overview of recent research in new drug discovery against diabetic complications based on bioactives from NPs, bridging the gap between the public research institutes and private companies working to find drugs to treat diabetes. To aid in reader comprehension, the text includes case studies and illustrated examples in relevant chapters. \u003c\/p\u003e\u003cp\u003ePart one presents chapters on fundamental concepts of diabetes mellitus (DM) and recent drug discovery progress along with the various druggable targets and challenges. Part two covers bioactive compounds targeting Type-1 Diabetes. Part three focuses on Type-2 Diabetes. In Part four, the contributors address gestational DM prevention and management with natural compounds. \u003c\/p\u003e\u003cp\u003eWritten by a global team of experts in the field, \u003ci\u003eNatural Products and their Bioactives in Antidiabetic Drug Discovery \u003c\/i\u003ecovers sample topics such as: \u003c\/p\u003e\u003cul\u003e\n\u003cli\u003eObesity risk factor in patients with T1DM and possible role of nutritional therapy in its management\u003c\/li\u003e \u003cli\u003eUse of natural non-insulin drugs as a novel approach to enhance therapeutic outcomes against T1DM\u003c\/li\u003e \u003cli\u003eEffectiveness of functional foods in intervening the diabetic complications and realistic results in clinical trials\u003c\/li\u003e \u003cli\u003eImplementation of nanotechnology in improving the bioavailability and reducing the threshold dose of bioactive compounds\u003c\/li\u003e \u003cli\u003eVarious antidiabetic mechanisms of action of different polyphenols and immunomodulatory role of NPs bioactives relevance in T1DM therapy\u003c\/li\u003e \u003cli\u003eEffects of natural products on genetics of gestational diabetes\u003c\/li\u003e\n\u003c\/ul\u003e \u003cp\u003eWith comprehensive coverage of recent research in new drug discovery against diabetic complications based on bioactives from NPs, \u003ci\u003eNatural Products and Their Bioactives in Antidiabetic Drug Discovery \u003c\/i\u003eis an essential resource for researchers and professionals involved in drug discovery and development, health care, medicinal chemistry, phytochemistry, plant science, and toxicology.\u003c\/p\u003e","brand":"Wiley","offers":[{"title":"Default Title","offer_id":47989677064421,"sku":"NP9781119983316","price":195.0,"currency_code":"USD","in_stock":false}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/1842\/7735\/files\/9781119983316.jpg?v=1761785065","url":"https:\/\/k12savings.com\/es\/products\/natural-products-and-their-bioactives-in-antidiabetic-drug-discovery-isbn-9781119983316","provider":"K12savings","version":"1.0","type":"link"}