{"product_id":"nanotoxicity-isbn-9780470741375","title":"Nanotoxicity","description":"Nanomaterials - substances smaller than 100 nanometers in size - have been added in recent years to an increasing numbers of consumer products used in day-to-day life; in food packaging, medical devices, pharmaceuticals, cosmetics, odor-resistant textiles and household appliances. The extensive application of nanomaterials in a wide range of products for human use poses a potential for toxicity risk to human health and the environment. Such adverse effects of nanomaterials on human health have triggered the development of a new scientific discipline known as “nanotoxicity” – the study of the toxicity of nanomaterials.  \u003cp\u003e\u003ci\u003eNanotoxicity: From\u003c\/i\u003e in vivo \u003ci\u003eand\u003c\/i\u003e in vitro \u003ci\u003eModels to Health Risks\u003c\/i\u003e provides up-to-date state-of-the-art information presented by recognized experts in this emerging new field in toxicology. It discusses the safety evaluation of nanomaterials in foods, drugs, medical devices, cosmetics and other regulated products and its use in risk analysis for potential regulatory use. Topics covered include:\u003c\/p\u003e \u003cul\u003e \u003cli\u003ebiomarkers for nanotoxicity assessment\u003c\/li\u003e \u003cli\u003enanotoxicity assessment by gene expression analysis\u003c\/li\u003e \u003cli\u003e\n\u003ci\u003ein vivo\u003c\/i\u003e and \u003ci\u003ein vitro\u003c\/i\u003e models for nanotoxicity testing\u003c\/li\u003e \u003cli\u003emechanisms of nanotoxicity\u003c\/li\u003e \u003cli\u003epharmakokinetics of nanomaterials\u003c\/li\u003e \u003cli\u003enanotoxicity of foods including food processing, food packaging and food safety\u003c\/li\u003e \u003cli\u003enanotoxicity of drugs including drug development and drug delivery\u003c\/li\u003e \u003cli\u003enanotoxicity of cosmetics and consumer products\u003c\/li\u003e \u003cli\u003ehealth and environmental impact of nanotoxicity\u003c\/li\u003e \u003cli\u003esafety evaluation of nanomaterials\u003c\/li\u003e \u003cli\u003eregulatory impact of nanomaterials\u003c\/li\u003e \u003c\/ul\u003e \u003cp\u003e\u003ci\u003eNanotoxicity: From\u003c\/i\u003e in vivo \u003ci\u003eand\u003c\/i\u003e in vitro \u003ci\u003eModels to Health Risks\u003c\/i\u003e is a valuable authoritative source of information for readers from a wide range of disciplines such as toxicology, pharmacology, drug toxicity and food and environmental sciences. The book will be useful to the research community in academia, industry, hospitals and government, as well as to government regulators and risk assessors of foods, drugs and environmental and agricultural products.\u003c\/p\u003e  Preface.  \u003cp\u003eList of Contributors.\u003c\/p\u003e \u003cp\u003eAcknowledgments.\u003c\/p\u003e \u003cp\u003e1 Characterization of Nanomaterials for Toxicological Evaluation (\u003ci\u003eKevin W. Powers, Maria Palazuelos, Scott C. Brown and Stephen M. Roberts\u003c\/i\u003e).\u003c\/p\u003e \u003cp\u003e2 Criteria and Implementation of Physical and Chemical Characteristics of Nanomaterials for Human Health Effects and Ecological Toxicity Studies (\u003ci\u003eChristie M. Sayes and David B. Warheit\u003c\/i\u003e).\u003c\/p\u003e \u003cp\u003e3 Considerations for the Design of Toxicity Studies of Inhaled Nanomedicines (\u003ci\u003eLea Ann Dailey\u003c\/i\u003e).\u003c\/p\u003e \u003cp\u003e4 High Aspect Ratio Nanoparticles and the Fibre Pathogenicity Paradigm (\u003ci\u003eCraig A. Poland, Rodger Duffin and Ken Donaldson\u003c\/i\u003e).\u003c\/p\u003e \u003cp\u003e5 Application of Zinc Oxide Quantum Dots in Food Safety (\u003ci\u003eTony Jin, Dazhi Sun, Howard Zhang and Hung-Jue Sue\u003c\/i\u003e).\u003c\/p\u003e \u003cp\u003e6 Evaluation of Nanotoxicity of Foods and Drugs: Biological Properties of Red Elemental Selenium at Nano Size (Nano-Se) \u003ci\u003eIn Vitro\u003c\/i\u003e and \u003ci\u003eIn Vivo\u003c\/i\u003e (\u003ci\u003eJinsong Zhang\u003c\/i\u003e).\u003c\/p\u003e \u003cp\u003e7 Evaluation of Toxicity of Nanostructures in Biological Systems (\u003ci\u003eAdam J. Gormley and Hamidreza Ghandehari\u003c\/i\u003e).\u003c\/p\u003e \u003cp\u003e8 Developing Bioassay Methods for Evaluating Pulmonary Hazards from Nanoscale or Fine Quartz\/Titanium Dioxide Particulate Materials (\u003ci\u003eDavid B. Warheit, Kenneth L. Reed and Christie M. Sayes\u003c\/i\u003e).\u003c\/p\u003e \u003cp\u003e9 Nanoparticles: Is Neurotoxicity a Concern? (\u003ci\u003eJianyong Wang, Wenjun Sun and Syed F. Ali\u003c\/i\u003e).\u003c\/p\u003e \u003cp\u003e10 Hepatotoxic Potential of Nanomaterials (\u003ci\u003eSaura C. Sahu\u003c\/i\u003e).\u003c\/p\u003e \u003cp\u003e11 Nanotoxicity in Blood: Effects of Engineered Nanomaterials on Platelets (\u003ci\u003eJan Simak\u003c\/i\u003e).\u003c\/p\u003e \u003cp\u003e12 Sources, Fate and Effects of Engineered Nanomaterials in the Aquatic Environment (\u003ci\u003eDavid S. Barber, Nancy D. Denslow, R. Joseph Griffitt and Christopher J. Martyniuk\u003c\/i\u003e).\u003c\/p\u003e \u003cp\u003e13 Nanotoxicity of Metal Oxide Nanoparticles \u003ci\u003ein Vivo\u003c\/i\u003e (\u003ci\u003eWeiyue Feng, Bing Wang and Yuliang Zhao\u003c\/i\u003e).\u003c\/p\u003e \u003cp\u003e14 \u003ci\u003eIn Vivo\u003c\/i\u003e Hypersensitive Pulmonary Disease Models for Nanotoxicity (\u003ci\u003eKen-ichiro Inoue and Hirohisa Takano\u003c\/i\u003e).\u003c\/p\u003e \u003cp\u003e15 \u003ci\u003eIn Vivo\u003c\/i\u003e and \u003ci\u003eIn Vitro\u003c\/i\u003e Models for Nanotoxicology Testing (\u003ci\u003eRosalba Gornati, Elena Papis, Mario Di Gioacchino, Enrico Sabbioni, Isabella Dalle Donne, Aldo Milzani and Giovanni Bernardini\u003c\/i\u003e).\u003c\/p\u003e \u003cp\u003e16 \u003ci\u003eIn Vitro\u003c\/i\u003e and \u003ci\u003eIn Vivo\u003c\/i\u003e Toxicity Study of Nanoparticles (\u003ci\u003eJayoung Jeong, Wan-Seob Cho, Seung Hee Kim and Myung-Haing Cho\u003c\/i\u003e).\u003c\/p\u003e \u003cp\u003e17 \u003ci\u003eIn Vitro\u003c\/i\u003e and \u003ci\u003eIn Vivo\u003c\/i\u003e Models for Nanotoxicity Testing (\u003ci\u003eKyung O. Yu, Laura K. Braydich-Stolle, David M. Mattie, John J. Schlager and Saber M. Hussain\u003c\/i\u003e).\u003c\/p\u003e \u003cp\u003e18 \u003ci\u003eIn Vitro\u003c\/i\u003e Models for Nanotoxicity Testing (\u003ci\u003eYinfa Ma\u003c\/i\u003e).\u003c\/p\u003e \u003cp\u003e19 \u003ci\u003eIn Vitro\u003c\/i\u003e Human Lung Cell Culture Models to Study the Toxic Potential of Nanoparticles (\u003ci\u003eFabian Blank, Peter Gehr and Barbara Rothen-Rutishauser\u003c\/i\u003e).\u003c\/p\u003e \u003cp\u003e20 Iron Oxide Magnetic Nanoparticle Nanotoxicity: Incidence and Mechanisms (\u003ci\u003eThomas R. Pisanic, Sungho Jin and Veronica I. Shubayev\u003c\/i\u003e).\u003c\/p\u003e \u003cp\u003e21 Toxicity Testing and Evaluation of Nanoparticles: Challenges in Risk Assessment (\u003ci\u003eDavid Y. Lai and Philip G. Sayre\u003c\/i\u003e).\u003c\/p\u003e \u003cp\u003e22 Evaluating Strategies For Risk Assessment of Nanomaterials (\u003ci\u003eNastassja Lewinski, Huiguang Zhu and Rebekah Drezek\u003c\/i\u003e).\u003c\/p\u003e \u003cp\u003e23 Strategies for Risk Assessment of Nanomaterials (\u003ci\u003eHae-Seong Yoon, Hyun-Kyung Kim, Dong Deuk Jang and Myung-Haing Cho\u003c\/i\u003e).\u003c\/p\u003e \u003cp\u003e24 Metal Nanoparticle Health Risk Assessment (\u003ci\u003eMario Di Gioacchino, Nicola Verna, Rosalba Gornati, Enrico Sabbioni and Giovanni Bernardini\u003c\/i\u003e).\u003c\/p\u003e \u003cp\u003e25 Application of Toxicology Studies in Assessing the Health Risks of Nanomaterials in Consumer Products (\u003ci\u003eJ.S. Tsuji, F.S. Mowat, S. Donthu and M. Reitman\u003c\/i\u003e).\u003c\/p\u003e \u003cp\u003e26 Safety Assessment of Engineered Nanomaterials in Direct Food Additives and Food Contact Materials (\u003ci\u003ePenelope A. Rice, Kimberly S. Cassidy, Jeremy Mihalov and T. Scott Thurmond\u003c\/i\u003e).\u003c\/p\u003e \u003cp\u003eIndex.\u003c\/p\u003e  \"I can certainly envisage this book being used widely. Indeed, an excellent and most timely book, clearly written, and sensitively related to nano; above all, it really 'speaks' to the realities of nanotoxicity. An additional bonus.....an important one at that.... Is .the list of references cited at the end of every contribution that must make the acquisition of the volume urgent and imperative.\" (\u003ci\u003eCurrent Engineering Practice\u003c\/i\u003e, 2010)\u003cbr\u003e \u003cbr\u003e  \u003cp\u003e\u003cstrong\u003eDr. Saura C. Sahu, Research Chemist, Division of Toxicology, Office of Applied Research and Safety Assessment, Center for Food Safety and Applied Nutrition, US Food and Drug Administration.\u003c\/strong\u003e\u003cbr\u003eDr. Sahu is the US Editor for the \u003cem\u003eJournal of Applied Toxicology\u003c\/em\u003e and the editor of \u003cem\u003eHepatotoxicity\u003c\/em\u003e (Wiley, Dec 2007), and \u003cem\u003eToxicogenomics\u003c\/em\u003e (Wiley, Oct 2008). \u003c\/p\u003e\u003cp\u003e\u003cstrong\u003eProfessor Daniel A. Casciano, Department of Pharmacology and Toxicology, University of Arkansas for Medical Sciences, Little Rock, AR, USA\u003c\/strong\u003e\u003cbr\u003eProfessor Casciano was former director of the US Food and Drug Administration's National Center for Toxicological Research in Jefferson, Arkansas, USA.   Nanomaterials - substances smaller than 100 nanometers in size - have been added in recent years to an increasing numbers of consumer products used in day-to-day life; in food packaging, medical devices, pharmaceuticals, cosmetics, odor-resistant textiles and household appliances. The extensive application of nanomaterials in a wide range of products for human use poses a potential for toxicity risk to human health and the environment. Such adverse effects of nanomaterials on human health have triggered the development of a new scientific discipline known as “nanotoxicity” – the study of the toxicity of nanomaterials.  \u003c\/p\u003e\u003cp\u003e\u003ci\u003eNanotoxicity: From\u003c\/i\u003e in vivo \u003ci\u003eand\u003c\/i\u003e in vitro \u003ci\u003eModels to Health Risks\u003c\/i\u003e provides up-to-date state-of-the-art information presented by recognized experts in this emerging new field in toxicology. It discusses the safety evaluation of nanomaterials in foods, drugs, medical devices, cosmetics and other regulated products and its use in risk analysis for potential regulatory use. Topics covered include:\u003c\/p\u003e \u003cul type=\"disc\"\u003e \u003cli\u003egeneral principles of nanotoxicology\u003c\/li\u003e \u003cli\u003eapplications of nanomaterials\u003c\/li\u003e \u003cli\u003esystemic and environmental nanoxicity\u003c\/li\u003e \u003cli\u003emodels for nanotoxicity testing\u003c\/li\u003e \u003cli\u003emechanisms of nanotoxicity\u003c\/li\u003e \u003cli\u003erisk analysis of nanomaterials \u003c\/li\u003e \u003c\/ul\u003e \u003cp\u003e\u003ci\u003eNanotoxicity: From\u003c\/i\u003e in vivo \u003ci\u003eand\u003c\/i\u003e in vitro \u003ci\u003eModels to Health Risks\u003c\/i\u003e is a valuable authoritative source of information for readers from a wide range of disciplines such as toxicology, pharmacology, drug toxicity and food and environmental sciences. The book will be useful to the research community in academia, industry, hospitals and government, as well as to government regulators and risk assessors of foods, drugs and environmental and agricultural products.\u003c\/p\u003e","brand":"Wiley","offers":[{"title":"Default Title","offer_id":47989673918693,"sku":"NP9780470741375","price":262.95,"currency_code":"USD","in_stock":false}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/1842\/7735\/files\/9780470741375.jpg?v=1761785052","url":"https:\/\/k12savings.com\/es\/products\/nanotoxicity-isbn-9780470741375","provider":"K12savings","version":"1.0","type":"link"}