{"product_id":"more-synthetic-approaches-to-nonaromatic-nitrogen-heterocycles-2-volume-set-isbn-9781119757122","title":"More Synthetic Approaches to Nonaromatic Nitrogen Heterocycles, 2 Volume Set","description":"\u003cb\u003eMore Synthetic Approaches to Nonaromatic Nitrogen Heterocycles\u003c\/b\u003e \u003cp\u003e\u003cb\u003eAn authoritative collection of resources discussing the latest trends in the synthesis of nonaromatic nitrogen heterocycles \u003c\/b\u003e \u003c\/p\u003e\u003cp\u003eWidely distributed in nature, nitrogen heterocycles are extremely common in synthetic substances found in pharmaceuticals, agrochemicals, and materials. The literature is evolving rapidly and explores newly emerging structures and medicines. \u003ci\u003eMore Synthetic Approaches to Nonaromatic Nitrogen Heterocycles\u003c\/i\u003e offers R\u0026amp;D professionals the opportunity to easily access a collection of the latest relevant research in the area.  \u003c\/p\u003e\u003cp\u003eIn the second two-volume set of this practical reference distinguished researcher Dr. Ana Maria M. M. Faisca Phillips delivers a collection of resources focusing on the newest and most widely applicable trends emerging in synthetic strategies for nonaromatic nitrogen heterocycles. With coverage of topics including organocatalysis, cascade reactions, flow chemistry in synthesis, cycloaddition reactions, metathesis, cross-coupling reactions, and electrochemistry, the book provides quick access to critical new avenues of synthesis.  \u003c\/p\u003e\u003cp\u003e\u003ci\u003eMore Synthetic Approaches to Nonaromatic Nitrogen Heterocycles: Volume 1 and 2\u003c\/i\u003e also offers readers:  \u003c\/p\u003e\u003cul\u003e\n\u003cli\u003eA thorough introduction to recent advances in the design and synthesis of cyclic peptidomimetics\u003c\/li\u003e \u003cli\u003eComprehensive explorations of fused heterocycles and transition metal promoted synthesis of isoindoline derivatives\u003c\/li\u003e \u003cli\u003ePractical discussions of 1,4-diazepane ring-based systems and recent advances in the synthesis of azepane-based compounds\u003c\/li\u003e \u003cli\u003eIn-depth examinations of strained aziridinium ions, asymmetric organocatalysis in alternative media, and the electrochemical synthesis of non-aromatic N-heterocycles\u003c\/li\u003e\n\u003c\/ul\u003e \u003cp\u003ePerfect for academic and industrial researchers in organic chemistry and synthesis, organometallic chemistry, pharmaceutical chemistry catalysis, and sustainable chemistry, \u003ci\u003eMore Synthetic Approaches to Nonaromatic Nitrogen Heterocycles: Volume 1 and 2\u003c\/i\u003e is an indispensable reference for anyone seeking an authoritative source of information on new and emerging trends in synthesis.Der dritte Teil einer umfangreichen Sammlung von Büchern über Synthesestrategien für nichtaromatische Stickstoffheterocyclen mit 15 Kapiteln über modernste Trends und Techniken. In diesem Werk werden einige der wichtigsten modernen Syntheseverfahren zur Gewinnung nichtaromatischer Stickstoffheterocyclen sowie ihre praktischen Anwendungen erläutert. Als zentrale Themen werden u.a. die Organokatalyse, Kaskadenreaktionen, Fließchemie in der Synthese, Cycloadditionsreaktionen, Metathese, Kreuzkupplungsreaktionen und die Elektrochemie betrachtet. Stickstoffheterocyclen sind eine wichtige Klasse chemischer Verbindungen, die in der Pharmazie, Agrochemie und Materialchemie Anwendung finden. Dieses Werk enthält Beiträge von Fachautoren aus 10 Ländern. \u003c\/p\u003e\u003cp\u003eList of Contributors\u003c\/p\u003e \u003cp\u003ePreface\u003c\/p\u003e \u003cp\u003eList of Common Abbreviations\u003c\/p\u003e \u003cp\u003e \u003c\/p\u003e \u003cp\u003ePART 1: CASCADE REACTIONS\u003c\/p\u003e \u003cp\u003e \u003c\/p\u003e \u003cp\u003e1             Unity is Strength: The Case of Cascade Reactions Combined with C–H Activation  1\u003c\/p\u003e \u003cp\u003e               Emanuele  Casali, Ervis Saraci and Giuseppe Zanoni\u003c\/p\u003e \u003cp\u003e              \u003c\/p\u003e \u003cp\u003e1.1         Introduction\u003c\/p\u003e \u003cp\u003e1.2         Rhodium Promoted Reactions\u003c\/p\u003e \u003cp\u003e1.3         Palladium Promoted Reactions\u003c\/p\u003e \u003cp\u003e1.4         Ruthenium Promoted Reactions\u003c\/p\u003e \u003cp\u003e1.5         Cobalt Promoted Reactions\u003c\/p\u003e \u003cp\u003e1.6         Miscellaneous\u003c\/p\u003e \u003cp\u003eReferences\u003c\/p\u003e \u003cp\u003e \u003c\/p\u003e \u003cp\u003e2             Chemo-enzymatic Cascade Reactions for the Synthesis of Chiral Intermediates\u003c\/p\u003e \u003cp\u003e               and Nonaromatic Nitrogen Heterocycles\u003c\/p\u003e \u003cp\u003eRodrigo O.M.A. de Souza, Raquel A.C. Leão, Marcelo A. Nascimento, Alexandre de S. França, Amanda S. de Miranda, Ivaldo I. Junior\u003c\/p\u003e \u003cp\u003e \u003c\/p\u003e \u003cp\u003e2.1         Introduction\u003c\/p\u003e \u003cp\u003e2.2         C–N Bond Construction Enzymes\u003c\/p\u003e \u003cp\u003e2.3         C–N Deracemization Enzymes\u003c\/p\u003e \u003cp\u003e2.4         Cascade Reactions\u003c\/p\u003e \u003cp\u003e2.4.1      Enzymatic Cascade Reactions\u003c\/p\u003e \u003cp\u003e2.4.2      Chemoenzymatic Cascade Reactions\u003c\/p\u003e \u003cp\u003eReferences\u003c\/p\u003e \u003cp\u003e \u003c\/p\u003e \u003cp\u003e3             Asymmetric Organocatalytic Cascade Reactions for the Synthesis of Nitrogen Heterocycles\u003c\/p\u003e \u003cp\u003eA. M. M. M. Faisca Phillips\u003c\/p\u003e \u003cp\u003e \u003c\/p\u003e \u003cp\u003e3.1 Introduction\u003c\/p\u003e \u003cp\u003e3.2 Three-membered Ring Heterocycles: Aziridines\u003c\/p\u003e \u003cp\u003e3.3 Four-membered Ring Heterocycles: The β-lactams\u003c\/p\u003e \u003cp\u003e3.4 Five-membered Rings\u003c\/p\u003e \u003cp\u003e3.4.1 Pyrrolidines\u003c\/p\u003e \u003cp\u003e3.4.2 Pyrrolidinones (-Lactams)\u003c\/p\u003e \u003cp\u003e3.4.3 Isoindolinones and Spirooxindoles\u003c\/p\u003e \u003cp\u003e3.5 Six-membered Rings\u003c\/p\u003e \u003cp\u003e3.5.1 Piperidines, Dihydropyridines and Tetrahydropyridines\u003c\/p\u003e \u003cp\u003e3.5.2 Piperidinones (-lactams)\u003c\/p\u003e \u003cp\u003e3.5.3 Dihydropyridinones\u003c\/p\u003e \u003cp\u003e3.5.4 Tetrahydroquinolines, Dihydroquinolines and Related Substances\u003c\/p\u003e \u003cp\u003e3.5.5 Hexahydropyridazines and Pyrimidinones\u003c\/p\u003e \u003cp\u003e3.6 Pyrrolo[3,2,1-ij]quinolines\u003c\/p\u003e \u003cp\u003e3.7 Cyclic Sulfamidates\u003c\/p\u003e \u003cp\u003e3.8 Miscellaneous\u003c\/p\u003e \u003cp\u003eConclusion\u003c\/p\u003e \u003cp\u003eReferences\u003c\/p\u003e \u003cp\u003e \u003c\/p\u003e \u003cp\u003e \u003c\/p\u003e \u003cp\u003ePART 2: SELECTED REACTIONS FOR THE SYNTHESIS OF NITROGEN HETEROCYCLES\u003c\/p\u003e \u003cp\u003e \u003c\/p\u003e \u003cp\u003e4             Synthesis of Nitrogen-Heterocycles Based on N-Heterocyclic Carbene Organocatalysis\u003c\/p\u003e \u003cp\u003e               Hideto Miyabe\u003c\/p\u003e \u003cp\u003e              \u003c\/p\u003e \u003cp\u003e \u003c\/p\u003e \u003cp\u003e4.1         Introduction\u003c\/p\u003e \u003cp\u003e4.2         NHC-catalyzed Cyclization\u003c\/p\u003e \u003cp\u003e4.3         NHC-catalyzed Annulation\u003c\/p\u003e \u003cp\u003e4.3.1      [3 + 2] Annulation\u003c\/p\u003e \u003cp\u003e4.3.2      [4 + 2] Annulation\u003c\/p\u003e \u003cp\u003e4.3.3      [3 + 3] Annulation\u003c\/p\u003e \u003cp\u003e4.3.4      [4 + 3] Annulation\u003c\/p\u003e \u003cp\u003e4.3.5      [2 + 2] Annulation\u003c\/p\u003e \u003cp\u003e4.4         Oxidative NHC-catalyzed Annulation\u003c\/p\u003e \u003cp\u003e4.4.1      Oxidative [3 + 2] Annulation\u003c\/p\u003e \u003cp\u003e4.4.2      Oxidative [4 + 2] Annulation\u003c\/p\u003e \u003cp\u003e4.4.3      Oxidative [3 + 3] Annulation\u003c\/p\u003e \u003cp\u003e4.4.4      Oxidative [4 + 3] Annulation\u003c\/p\u003e \u003cp\u003e4.4.5      Oxidative [2 + 2] Annulation\u003c\/p\u003e \u003cp\u003e4.5         Asymmetric Dearomatization\u003c\/p\u003e \u003cp\u003e4.6         Cooperative Catalysis of NHC and Transition-Metal Catalysts\u003c\/p\u003e \u003cp\u003e4.7         Other NHC-catalyzed Reactions\u003c\/p\u003e \u003cp\u003e4.8         Conclusion and Outlook\u003c\/p\u003e \u003cp\u003eReferences\u003c\/p\u003e \u003cp\u003e \u003c\/p\u003e \u003cp\u003e5             Synthesis of N-Heterocycles via [3 + n] Cycloaddition Reactions of Vinyl Metal Carbene Intermediates\u003c\/p\u003e \u003cp\u003e               Ming Bao, Su Zhou, and Xinfang Xu\u003c\/p\u003e \u003cp\u003e              \u003c\/p\u003e \u003cp\u003e \u003c\/p\u003e \u003cp\u003e5.1         Introduction\u003c\/p\u003e \u003cp\u003e5.2         [3 + 1]-Cycloaddition\u003c\/p\u003e \u003cp\u003e5.3         [3 + 2]-Cycloaddition\u003c\/p\u003e \u003cp\u003e5.4         [3 + 3]-Cycloaddition\u003c\/p\u003e \u003cp\u003e5.4.1      [3 + 3]-Cycloaddition with Nitrone\u003c\/p\u003e \u003cp\u003e5.4.2      [3 + 3]-Cycloaddition with Azomethine Imines\u003c\/p\u003e \u003cp\u003e5.4.3      [3 + 3]-Cycloaddition with Other 1,3-Dipoles\u003c\/p\u003e \u003cp\u003e5.5         [3 + 4]-Cycloaddition\u003c\/p\u003e \u003cp\u003e5.5.1      [3 + 4]-Cycloaddition with N-Heterocycles\u003c\/p\u003e \u003cp\u003e5.5.2      [3 + 4]-Cycloaddition with α,-Unsaturated Imines\u003c\/p\u003e \u003cp\u003e5.5.        Other Types of [3 + 4]-Cycloadditions\u003c\/p\u003e \u003cp\u003e5.6         [3 + 5]-Cycloaddition\u003c\/p\u003e \u003cp\u003e5.7         Intramolecular Cyclization via Carbene\/Alkyne Metathesis Process\u003c\/p\u003e \u003cp\u003e5.8         Summary and Outlook\u003c\/p\u003e \u003cp\u003eReferences\u003c\/p\u003e \u003cp\u003e \u003c\/p\u003e \u003cp\u003e6             Recent Progress in the Synthesis of Amine-containing Heterocycles by Metathesis Reactions\u003c\/p\u003e \u003cp\u003e               Zeyue Zhang, Damien Hazelard, and Philippe Compain\u003c\/p\u003e \u003cp\u003e              \u003c\/p\u003e \u003cp\u003e \u003c\/p\u003e \u003cp\u003e6.1         Introduction\u003c\/p\u003e \u003cp\u003e6.2         Five-membered Cyclic Amines\u003c\/p\u003e \u003cp\u003e6.3         Six-membered Cyclic Amines\u003c\/p\u003e \u003cp\u003e6.3.1      Natural Products and Related Compounds\u003c\/p\u003e \u003cp\u003e6.3.2      Sugar Mimetics\u003c\/p\u003e \u003cp\u003e6.3.3      RCM of Phenylamines and Related Analogues\u003c\/p\u003e \u003cp\u003e6.3.4      Miscellaneous\u003c\/p\u003e \u003cp\u003e6.4         Seven-membered to Macrocyclic Amines\u003c\/p\u003e \u003cp\u003e6.5         Tandem Reactions\u003c\/p\u003e \u003cp\u003e6.6         Conclusion\u003c\/p\u003e \u003cp\u003eReferences\u003c\/p\u003e \u003cp\u003e \u003c\/p\u003e \u003cp\u003e7             Metal-Catalyzed Synthesis of N-Heterocycles Via Borrowing-Hydrogen Annulation\u003c\/p\u003e \u003cp\u003e               A. Sofia Santos, Daniel Raydan, Nuno Viduedo, M. Manuel B. Marques, and Beatriz Royo\u003c\/p\u003e \u003cp\u003e \u003c\/p\u003e \u003cp\u003e7.1         Introduction\u003c\/p\u003e \u003cp\u003e7.2         Metal-Catalyzed Borrowing Hydrogen Annulation Reactions\u003c\/p\u003e \u003cp\u003e7.2.1      Rh-Catalyzed Borrowing Hydrogen Reactions\u003c\/p\u003e \u003cp\u003e7.2.2      Ru-Catalyzed Borrowing Hydrogen Reactions\u003c\/p\u003e \u003cp\u003e7.2.3      Ir-Catalyzed Borrowing Hydrogen Reactions\u003c\/p\u003e \u003cp\u003e7.2.4      Fe-Catalyzed Borrowing Hydrogen Reactions\u003c\/p\u003e \u003cp\u003e7.2.5      Ni-Catalyzed Borrowing Hydrogen Reactions\u003c\/p\u003e \u003cp\u003e7.3         Conclusions\u003c\/p\u003e \u003cp\u003eReferences\u003c\/p\u003e \u003cp\u003e \u003c\/p\u003e \u003cp\u003e8             Synthesis of N-Heterocycles Via Metal-Catalyzed Intramolecular Buchwald-Hartwig C-N Cross Coupling Reactions\u003c\/p\u003e \u003cp\u003e               Auxiliadora Prieto\u003c\/p\u003e \u003cp\u003e \u003c\/p\u003e \u003cp\u003e8.1         Introduction\u003c\/p\u003e \u003cp\u003e8.2.        Applications of Intramolecular Pd-Catalyzed N-Arylation of amine in the Synthesis of Nonaromatic Heterocycles.\u003c\/p\u003e \u003cp\u003e8.2.1.     Synthesis of Five-membered N-Heterocycles.\u003c\/p\u003e \u003cp\u003e8.2.2.     Synthesis of Six-membered N-Heterocycles.\u003c\/p\u003e \u003cp\u003e8.2.3.     Applications in the Synthesis of both Five- and Six-membered N-Heterocycles\u003c\/p\u003e \u003cp\u003e8.2.4.     Synthesis of Seven-membered N-Heterocycles\u003c\/p\u003e \u003cp\u003e8.3.        Applications of Intramolecular Pd-Catalyzed N-arylation of amide in the Synthesis of Nonaromatic Heterocycles.\u003c\/p\u003e \u003cp\u003e8.3.1.     Applications in the Synthesis of Five-membered N-Heterocycles.\u003c\/p\u003e \u003cp\u003e8.3.2.     Application in the Synthesis of Six-membered N-Heterocycles\u003c\/p\u003e \u003cp\u003e8.3.3.     Application in the Synthesis of Seven-membered N-Heterocycles\u003c\/p\u003e \u003cp\u003e8.4.        Intramolecular Pd-Catalyzed Arylation of Sulfonamides.\u003c\/p\u003e \u003cp\u003e8.5         Applications of the Intramolecular Buchwald-Hartwig Amination in the Synthesis of Natural Products.\u003c\/p\u003e \u003cp\u003e8.6         Conclusion\u003c\/p\u003e \u003cp\u003eReferences\u003c\/p\u003e \u003cp\u003e \u003c\/p\u003e \u003cp\u003e9             Synthesis of Nonaromatic Nitrogen Heterocycles Via Singlet Oxygen\u003c\/p\u003e \u003cp\u003e               João Tomé, Kelly A.D.F. Castro, Leandro M. O. Lourenço, Roberto Santana Da Silva,\u003c\/p\u003e \u003cp\u003e              \u003c\/p\u003e \u003cp\u003e \u003c\/p\u003e \u003cp\u003e9.1         Introduction\u003c\/p\u003e \u003cp\u003e9.2         Singlet Oxygen on Organic Synthesis\u003c\/p\u003e \u003cp\u003e9.2.1      Oxidation of Bipyrroles\u003c\/p\u003e \u003cp\u003e9.2.2      Synthesis of (R)-methylnaltrexone\u003c\/p\u003e \u003cp\u003e9.2.3      Synthesis of Glochidine and Glochidicine\u003c\/p\u003e \u003cp\u003e9.2.4      Synthesis of γ-lactams via One-pot Synthesis\u003c\/p\u003e \u003cp\u003e9.2.5      Synthesis of the Melohenine B\u003c\/p\u003e \u003cp\u003e9.2.6      Synthesis of Pyrrolidine Derivatives by [2 + 3] Cycloaddition, via 1O2 Mediated 1,3-dipole\u003c\/p\u003e \u003cp\u003e9.2.7      Synthesis of Pandamarine\u003c\/p\u003e \u003cp\u003e9.2.8      Preparation of Bicyclic Lactam\u003c\/p\u003e \u003cp\u003e9.2.9      Synthesis of Alkaloids\u003c\/p\u003e \u003cp\u003e9.2.10   Synthesis of Azaspiro Frameworks\u003c\/p\u003e \u003cp\u003e9.2.11 Preparation of Tetrahydropyranopyrrolones\u003c\/p\u003e \u003cp\u003e9.2.12 Synthesis of 2-oxindoles\u003c\/p\u003e \u003cp\u003e9.2.13 Synthesis of Several Natural Products from an Amino Furan Derivative\u003c\/p\u003e \u003cp\u003e9.2.14 Synthesis of Peptide-fluorescent Probes\u003c\/p\u003e \u003cp\u003e9.2.15 Synthesis of Tetrahydroquinoline\u003c\/p\u003e \u003cp\u003e9.3         Conclusion\u003c\/p\u003e \u003cp\u003eReferences\u003c\/p\u003e \u003cp\u003e \u003c\/p\u003e \u003cp\u003e10           Cobalt-catalysed Carbonylation for the Synthesis of N-Heterocyclic Compounds\u003c\/p\u003e \u003cp\u003e               Anup Paul and Armando J.L. Pombeiro\u003c\/p\u003e \u003cp\u003e              \u003c\/p\u003e \u003cp\u003e \u003c\/p\u003e \u003cp\u003e1.            Introduction\u003c\/p\u003e \u003cp\u003e2.            Cobalt-catalysed Carbonylation for the Synthesis of N-heterocyclic Compounds Using CO Gas as CO source\u003c\/p\u003e \u003cp\u003e3.            Cobalt-catalysed Carbonylation for the Snthesis of N-heterocycles Using CO Surrogates\u003c\/p\u003e \u003cp\u003e4.            Conclusions\u003c\/p\u003e \u003cp\u003eReferences\u003c\/p\u003e \u003cp\u003e \u003c\/p\u003e \u003cp\u003e11           Enantioselective Synthesis of Nitrogen Heterocycles Using Chiral Hypervalent Iodine Reagents\u003c\/p\u003e \u003cp\u003e               Ana Maria Faisca Phillips and Armando J.L. Pombeiro\u003c\/p\u003e \u003cp\u003e \u003c\/p\u003e \u003cp\u003e11.1       Introduction\u003c\/p\u003e \u003cp\u003e11.2       The Historical Development of Chiral Hypervalent Iodine Reagents\u003c\/p\u003e \u003cp\u003e11.3       Synthesis with Chiral Hypervalent Iodine Reagents\u003c\/p\u003e \u003cp\u003e11.3.1   Difunctionalization of Alkenes\u003c\/p\u003e \u003cp\u003e11.3.2   Dearomatization Reactions\u003c\/p\u003e \u003cp\u003e11.3.3   α-Functionalization of Carbonyl Compounds\u003c\/p\u003e \u003cp\u003e11.4       Conclusion\u003c\/p\u003e \u003cp\u003eReferences\u003c\/p\u003e \u003cp\u003e \u003c\/p\u003e \u003cp\u003ePART III. SPECIAL TECHNIQUES\u003c\/p\u003e \u003cp\u003e \u003c\/p\u003e \u003cp\u003e12           Continuous Flow Chemistry\u003c\/p\u003e \u003cp\u003e               Marcus Baumann\u003c\/p\u003e \u003cp\u003e              \u003c\/p\u003e \u003cp\u003e \u003c\/p\u003e \u003cp\u003e12.1       Introduction To Modern Flow Chemistry\u003c\/p\u003e \u003cp\u003e12.2       Value of Heterocyclic Chemistry for Modern Drug Discovery Programs\u003c\/p\u003e \u003cp\u003e12.3       Case Studies of Flow Chemistry Applied to Heterocyclic Targets\u003c\/p\u003e \u003cp\u003e12.3.1    Flow Synthesis of Three-membered Saturated Heterocycles\u003c\/p\u003e \u003cp\u003e12.3.2    Flow Synthesis of Four-membered Saturated Heterocycles\u003c\/p\u003e \u003cp\u003e12.3.3    Flow Synthesis of Five-membered Saturated Heterocycles\u003c\/p\u003e \u003cp\u003e12.3.4    Flow Synthesis of Six-membered Saturated Heterocycles\u003c\/p\u003e \u003cp\u003e12.3.5    Flow Synthesis of Seven-membered Saturated Heterocycles\u003c\/p\u003e \u003cp\u003e12.3.6    Flow Synthesis of Macrocyclic Saturated Heterocycles\u003c\/p\u003e \u003cp\u003e12.4       Assessment of the Merits of Continuous Flow Processing for Heterocycle Synthesis\u003c\/p\u003e \u003cp\u003e12.5       Summary and Conclusions\u003c\/p\u003e \u003cp\u003eReferences\u003c\/p\u003e \u003cp\u003e \u003c\/p\u003e \u003cp\u003e13           The Electrochemical Synthesis of Non-Aromatic N-Heterocycles\u003c\/p\u003e \u003cp\u003eOana R. Luca\u003c\/p\u003e \u003cp\u003e \u003c\/p\u003e \u003cp\u003e13.1       Introduction\u003c\/p\u003e \u003cp\u003e13.2       Laws of Organic Electrosynthesis\u003c\/p\u003e \u003cp\u003e13.2.1    Types of Electrolyses\u003c\/p\u003e \u003cp\u003e13.2.2    Diagnostic Analytical Methods: Voltammetry\u003c\/p\u003e \u003cp\u003e13.3.      Construction of Three- and Four Membered Non-Aromatic Heterocycles\u003c\/p\u003e \u003cp\u003e13.3.1 Aziridines\u003c\/p\u003e \u003cp\u003e13.3.2 Epoxides\u003c\/p\u003e \u003cp\u003e13.3.3 Azetidines\u003c\/p\u003e \u003cp\u003e13.4       Construction of Five Six and Seven Membered Non-Aromatic Heterocycles\u003c\/p\u003e \u003cp\u003e13.4.1   Pyrrolidines\u003c\/p\u003e \u003cp\u003e13.4.2   Indolines and dihydrobenzofurans\u003c\/p\u003e \u003cp\u003e13.4.3   Pyrrolidinones, 5-membered Cyclic Carbamates and Derivatives\u003c\/p\u003e \u003cp\u003e13.4.4   Tetrahydrooxazole and Tetrahydrooxazine Derivatives\u003c\/p\u003e \u003cp\u003e13.4.5   6-membered Amides, Carbamates, and Derivatives\u003c\/p\u003e \u003cp\u003e13.5       Construction of Nonaromatic Heterocycles with Fused Polycyclic Systems\u003c\/p\u003e \u003cp\u003e13.5.1   Nonaromatic Heterocycles from Phtalimides and Succinimides\u003c\/p\u003e \u003cp\u003e13.5.2   Polyciclic Peptides\u003c\/p\u003e \u003cp\u003e13.5.3   Polyclic Ureas\u003c\/p\u003e \u003cp\u003e13.5.5   Ring-fused Quinones\u003c\/p\u003e \u003cp\u003eConclusion\u003c\/p\u003e \u003cp\u003eReferences\u003c\/p\u003e \u003cp\u003e \u003c\/p\u003e \u003cp\u003e14          Asymmetric Organocatalysis in Alternative Media\u003c\/p\u003e \u003cp\u003e               Luis C. Branco, Verônica Diniz, Karolina Zalewska, and Miguel M. Santos\u003c\/p\u003e \u003cp\u003e              \u003c\/p\u003e \u003cp\u003e \u003c\/p\u003e \u003cp\u003e14.1       Introduction\u003c\/p\u003e \u003cp\u003e14.2       Water as Reaction Medium\u003c\/p\u003e \u003cp\u003e14.3       Ionic Liquids as Alternative Media\u003c\/p\u003e \u003cp\u003e14.4       Miscellaneous Alternative Reaction Media\u003c\/p\u003e \u003cp\u003e14.5       Conclusions\u003c\/p\u003e \u003cp\u003eReferences\u003c\/p\u003e \u003cp\u003e \u003c\/p\u003e \u003cp\u003ePART IV. SYNTHETIC METHODS FOR SPECIAL COMPOUND CLASSES\u003c\/p\u003e \u003cp\u003e \u003c\/p\u003e \u003cp\u003e15           The Strained Aziridinium Ion\u003c\/p\u003e \u003cp\u003e               Jala Ranjith and Hyun-Joon Ha\u003c\/p\u003e \u003cp\u003e              \u003c\/p\u003e \u003cp\u003e \u003c\/p\u003e \u003cp\u003e15.1       Introduction\u003c\/p\u003e \u003cp\u003e15.2       Formation of Aziridinium Ions\u003c\/p\u003e \u003cp\u003e15.3       Ring Opening of Aziridinium Ion\u003c\/p\u003e \u003cp\u003e15.4       Synthetic Applications\u003c\/p\u003e \u003cp\u003e15.5       Bicyclic Aziridinium Ion and its Application\u003c\/p\u003e \u003cp\u003eAckowledgments\u003c\/p\u003e \u003cp\u003eReferences\u003c\/p\u003e \u003cp\u003e \u003c\/p\u003e \u003cp\u003e16           Recent advances on the synthesis of azepane-based compounds\u003c\/p\u003e \u003cp\u003e               Maria Assunta Chiacchio, Laura Legnani, Ugo Chiacchio, and Daniela Iannazzo\u003c\/p\u003e \u003cp\u003e \u003c\/p\u003e \u003cp\u003e16.1       Introduction\u003c\/p\u003e \u003cp\u003e16.2       Azepane Synthesis\u003c\/p\u003e \u003cp\u003e16.2.1    Synthesis of Substituted Azepanes\u003c\/p\u003e \u003cp\u003e16.2.2 Synthesis of Ring-fused Azepanes\u003c\/p\u003e \u003cp\u003e16.2.3 Synthesis of Azepane-based Alkaloids\u003c\/p\u003e \u003cp\u003eConclusion\u003c\/p\u003e \u003cp\u003e \u003c\/p\u003e \u003cp\u003e \u003c\/p\u003e \u003cp\u003e \u003c\/p\u003e \u003cp\u003e \u003c\/p\u003e \u003cp\u003e \u003c\/p\u003e \u003cp\u003e \u003c\/p\u003e \u003cp\u003e \u003c\/p\u003e \u003cp\u003e \u003c\/p\u003e \u003cp\u003e17           1,4-Diazepane Ring-based Systems\u003c\/p\u003e \u003cp\u003e               Eduarda M.P. Silva, Pedro A.M.M. Varandas, and Artur M.S. Silva\u003c\/p\u003e \u003cp\u003e \u003c\/p\u003e \u003cp\u003e17.1       Introduction\u003c\/p\u003e \u003cp\u003e17.2       Reductive Amination\u003c\/p\u003e \u003cp\u003e17.3       Mitsunobu Amination\u003c\/p\u003e \u003cp\u003e17.4       1,3-Dipolar Cycloaddition\u003c\/p\u003e \u003cp\u003e17.5       Multicomponent Reactions\u003c\/p\u003e \u003cp\u003e17.6       Other Methods\u003c\/p\u003e \u003cp\u003eConclusions\u003c\/p\u003e \u003cp\u003eReferences\u003c\/p\u003e \u003cp\u003e \u003c\/p\u003e \u003cp\u003e18           Transition Metal Promoted Synthesis of Isoindoline Derivatives\u003c\/p\u003e \u003cp\u003e               Laura A. Aronica and Gianluigi Albano\u003c\/p\u003e \u003cp\u003e \u003c\/p\u003e \u003cp\u003e18.1       Introduction\u003c\/p\u003e \u003cp\u003e18.2       Synthesis of Isoindolines\u003c\/p\u003e \u003cp\u003e18.2.1    [2+2+2] Cycloaddition Reactions\u003c\/p\u003e \u003cp\u003e18.2.2    Transition Metal-promoted Diels-Alder reactions\u003c\/p\u003e \u003cp\u003e18.2.3    Transition Metal-promoted Cyclization of Ortho-substituted Benzyl Amines (and Derivatives)\u003c\/p\u003e \u003cp\u003e18.2.4    Transition Metal-promoted 5-exo-dig Cyclization by C-C Bond Formation\u003c\/p\u003e \u003cp\u003e18.2.5    Miscellaneous\u003c\/p\u003e \u003cp\u003e18.2.6    Conclusions and Perspectives\u003c\/p\u003e \u003cp\u003eReferences\u003c\/p\u003e \u003cp\u003e \u003c\/p\u003e \u003cp\u003e19          1,2-Benzisothiazole 1,1-Dioxide (Saccharinate)-Based Compounds: Synthesis, Reactivity and    Applications\u003c\/p\u003e \u003cp\u003e               Luís M.T. Frija, André L. Fernandes, Bruno Guerreiro, and M. Lurdes S. Cristiano\u003c\/p\u003e \u003cp\u003e \u003c\/p\u003e \u003cp\u003e19.1       Introduction\u003c\/p\u003e \u003cp\u003e19.2       Synthesis of Saccharinate-based Conjugates\u003c\/p\u003e \u003cp\u003e19.3       Applications\u003c\/p\u003e \u003cp\u003e19.3.1    Ionic Liquids\u003c\/p\u003e \u003cp\u003e19.3.2    Coordination Chemistry\u003c\/p\u003e \u003cp\u003e19.3.3    Biological Activity and Medical Uses\u003c\/p\u003e \u003cp\u003e19.4       Concluding Remarks\u003c\/p\u003e \u003cp\u003eReferences\u003c\/p\u003e \u003cp\u003e \u003c\/p\u003e \u003cp\u003e20          Fused Heterocycles\u003c\/p\u003e \u003cp\u003e               Arruje Hameed, Muhammad Abdul Qayyum, Abdur Rehman, Touseef Ur Rehman, Anwar Ahmad, and Tahir Farooq\u003c\/p\u003e \u003cp\u003e \u003c\/p\u003e \u003cp\u003e20.1       Introduction\u003c\/p\u003e \u003cp\u003e20.1       Recent Developments for Facile Synthesis and Applications of 1,2,4-Triazole Fused Heterocycles\u003c\/p\u003e \u003cp\u003e20.1.1    1,2,4-Triazole-fused Heterocycles as Energetic Materials\u003c\/p\u003e \u003cp\u003e20.1.2    1,2,4-Triazole-fused Heterocycles as Building Blocks\u003c\/p\u003e \u003cp\u003e20.2       Recent Developments for Facile Synthesis of 1,2,3-Triazole-fused Heterocycles\u003c\/p\u003e \u003cp\u003e20.2.1    1,2,3-Triazole-fused Heterocycles as Bioactive Scaffolds\u003c\/p\u003e \u003cp\u003e20.2.2    1,2,3-Triazole-fused Heterocycles as Functional Materials\u003c\/p\u003e \u003cp\u003e20.3       Conclusion\u003c\/p\u003e \u003cp\u003eReferences\u003c\/p\u003e \u003cp\u003e \u003c\/p\u003e \u003cp\u003e \u003c\/p\u003e \u003cp\u003e21          Recent Advances in the Design and Synthesis of Cyclic Peptidomimetics\u003c\/p\u003e \u003cp\u003e               Arruje Hameed, Amjad Hameed, Ghulam Hussain, Hafiz Abdul Qayyum, Muhammad Fayyaz Farid, and Tahir Farooq\u003c\/p\u003e \u003cp\u003e \u003c\/p\u003e \u003cp\u003e21.1       Introduction\u003c\/p\u003e \u003cp\u003e21.2       Click-mediated Approaches for Cyclic Peptidomimetics\u003c\/p\u003e \u003cp\u003e21.3       Enzyme-mediated Approaches for Cyclic Peptidomimetics\u003c\/p\u003e \u003cp\u003e21.4       Solid-phase Synthesis of Cyclic Peptidomimetics\u003c\/p\u003e \u003cp\u003e21.5       Conclusion\u003c\/p\u003e References \u003cp\u003e\u003cb\u003eAna Maria M.M. Faisca Phillips, PhD,\u003c\/b\u003e is Researcher at the Coordination Chemistry and Catalysis Group, Centro de Química Estrutural, Instituto Superior Técnico Universidade de Lisboa. \u003c\/p\u003e  \u003cp\u003e\u003cb\u003eAn authoritative collection of resources discussing the latest trends in the synthesis of nonaromatic nitrogen heterocycles \u003c\/b\u003e\u003c\/p\u003e \u003cp\u003eWidely distributed in nature, nitrogen heterocycles are extremely common in synthetic substances found in pharmaceuticals, agrochemicals, and materials. The literature is evolving rapidly and explores newly emerging structures and medicines. \u003ci\u003eMore Synthetic Approaches to Nonaromatic Nitrogen Heterocycles\u003c\/i\u003e offers R\u0026amp;D professionals the opportunity to easily access a collection of the latest relevant research in the area.  \u003c\/p\u003e\u003cp\u003eIn the second two-volume set of this practical reference distinguished researcher Dr. Ana Maria M. M. Faisca Phillips delivers a collection of resources focusing on the newest and most widely applicable trends emerging in synthetic strategies for nonaromatic nitrogen heterocycles. With coverage of topics including organocatalysis, cascade reactions, flow chemistry in synthesis, cycloaddition reactions, metathesis, cross-coupling reactions, and electrochemistry, the book provides quick access to critical new avenues of synthesis.  \u003c\/p\u003e\u003cp\u003e\u003ci\u003eMore Synthetic Approaches to Nonaromatic Nitrogen Heterocycles: Volume 1 and 2\u003c\/i\u003e also offers readers:  \u003c\/p\u003e\u003cul\u003e\n\u003cli\u003eA thorough introduction to recent advances in the design and synthesis of cyclic peptidomimetics\u003c\/li\u003e \u003cli\u003eComprehensive explorations of fused heterocycles and transition metal promoted synthesis of isoindoline derivatives\u003c\/li\u003e \u003cli\u003ePractical discussions of 1,4-diazepane ring-based systems and recent advances in the synthesis of azepane-based compounds\u003c\/li\u003e \u003cli\u003eIn-depth examinations of strained aziridinium ions, asymmetric organocatalysis in alternative media, and the electrochemical synthesis of non-aromatic N-heterocycles\u003c\/li\u003e\n\u003c\/ul\u003e \u003cp\u003ePerfect for academic and industrial researchers in organic chemistry and synthesis, organometallic chemistry, pharmaceutical chemistry catalysis, and sustainable chemistry, \u003ci\u003eMore Synthetic Approaches to Nonaromatic Nitrogen Heterocycles: Volume 1 and 2\u003c\/i\u003e is an indispensable reference for anyone seeking an authoritative source of information on new and emerging trends in synthesis.\u003c\/p\u003e","brand":"Wiley","offers":[{"title":"Default Title","offer_id":47989654749413,"sku":"NP9781119757122","price":345.95,"currency_code":"USD","in_stock":false}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/1842\/7735\/files\/9781119757122.jpg?v=1761784975","url":"https:\/\/k12savings.com\/es\/products\/more-synthetic-approaches-to-nonaromatic-nitrogen-heterocycles-2-volume-set-isbn-9781119757122","provider":"K12savings","version":"1.0","type":"link"}