{"product_id":"molecular-and-quantitative-animal-genetics-isbn-9781118677407","title":"Molecular and Quantitative Animal Genetics","description":"\u003cp\u003eAnimal genetics is a foundational discipline in the fields of animal science, animal breeding, and veterinary sciences. While genetics underpins the healthy development and breeding of all living organisms, this is especially true in domestic animals, specifically with respect to breeding for key traits.  \u003c\/p\u003e \u003cp\u003e\u003ci\u003eMolecular and Quantitative Animal Genetics \u003c\/i\u003eis a new textbook that takes an innovative approach, looking at both quantitative and molecular breeding approaches. The bookprovides a comprehensive introduction to genetic principles and their applications in animal breeding. This text provides a useful overview for those new to the field of animal genetics and breeding, covering a diverse array of topics ranging from population and quantitative genetics to epigenetics and biotechnology. \u003ci\u003eMolecular and Quantitative Animal Genetics \u003c\/i\u003ewill be an important and invaluable educational resource for undergraduate and graduate students and animal agriculture professionals.\u003c\/p\u003e \u003cbr\u003e Divided into six sections pairing fundamental principles with useful applications, the book's comprehensive coverage will make it an ideal fit for students studying animal breeding and genetics at any level.Die Tiergenetik ist ein zentrales Thema in Wissenschaftsprogrammen für höhere Semester. Animal Genetics füllt eine Lücke im bestehenden Literaturkanon: genetische Prinzipien und deren Anwendung bei Nutz- und Haustieren werden vorgestellt. Ausführlich behandelt werden u.a. die Populations- und quantitative Genetik, die Epigenetik, Biotechnologie und Zucht. Als Lehrwerk für höhere Semester ist Animal Genetics unersetzlich. \u003cp\u003eContributors ix\u003c\/p\u003e \u003cp\u003eManuscript reviewers xi\u003c\/p\u003e \u003cp\u003ePreface xiii\u003c\/p\u003e \u003cp\u003e\u003cb\u003e1 Decoding and Encoding the “DNA” of Teaching and Learning in College Classrooms 1\u003cbr\u003e\u003c\/b\u003e\u003ci\u003eMichel A. Wattiaux\u003c\/i\u003e\u003c\/p\u003e \u003cp\u003eIntroduction 1\u003c\/p\u003e \u003cp\u003eTeaching and learning: definitions 1\u003c\/p\u003e \u003cp\u003eUnderstanding learning 2\u003c\/p\u003e \u003cp\u003eUnderstanding teaching 5\u003c\/p\u003e \u003cp\u003eImplications for classroom design in the twenty-first century 6\u003c\/p\u003e \u003cp\u003eFinal thoughts 9\u003c\/p\u003e \u003cp\u003eReferences 10\u003c\/p\u003e \u003cp\u003eReview questions 11\u003c\/p\u003e \u003cp\u003e\u003cb\u003eSection 1: Quantitative and Population Genetics 13\u003c\/b\u003e\u003c\/p\u003e \u003cp\u003e\u003cb\u003e2 Mating Systems: Inbreeding and Inbreeding Depression 15\u003cbr\u003e\u003c\/b\u003e\u003ci\u003eDavid L. Thomas\u003c\/i\u003e\u003c\/p\u003e \u003cp\u003eIntroduction 15\u003c\/p\u003e \u003cp\u003eInbreeding 15\u003c\/p\u003e \u003cp\u003eCause of inbreeding depression 18\u003c\/p\u003e \u003cp\u003eQuantifying inbreeding 20\u003c\/p\u003e \u003cp\u003eGenomics and inbreeding 23\u003c\/p\u003e \u003cp\u003eSummary 23\u003c\/p\u003e \u003cp\u003eFurther reading 24\u003c\/p\u003e \u003cp\u003eReferences 24\u003c\/p\u003e \u003cp\u003eReview questions 24\u003c\/p\u003e \u003cp\u003e\u003cb\u003e3 Genomic Selection Inbreeding and Crossbreeding in Dairy Cattle 25\u003cbr\u003e\u003c\/b\u003e\u003ci\u003eKent Weigel\u003c\/i\u003e\u003c\/p\u003e \u003cp\u003eIntroduction 25\u003c\/p\u003e \u003cp\u003eGenomic selection 25\u003c\/p\u003e \u003cp\u003eCrossbreeding 28\u003c\/p\u003e \u003cp\u003eInbreeding and genetic defects 29\u003c\/p\u003e \u003cp\u003eSummary 30\u003c\/p\u003e \u003cp\u003eReferences 30\u003c\/p\u003e \u003cp\u003eReview questions 31\u003c\/p\u003e \u003cp\u003e\u003cb\u003e4 Basic Genetic Model for Quantitative Traits 33\u003cbr\u003e\u003c\/b\u003e\u003ci\u003eGuilherme J. M. Rosa\u003c\/i\u003e\u003c\/p\u003e \u003cp\u003eIntroduction 33\u003c\/p\u003e \u003cp\u003eQuantitative traits 33\u003c\/p\u003e \u003cp\u003eExpected value and variance: the normal distribution 33\u003c\/p\u003e \u003cp\u003eBasic genetic model for quantitative traits 35\u003c\/p\u003e \u003cp\u003eHeritability and selection 35\u003c\/p\u003e \u003cp\u003ePredicting rate of genetic change from selection 36\u003c\/p\u003e \u003cp\u003eFurther reading 37\u003c\/p\u003e \u003cp\u003eReferences 37\u003c\/p\u003e \u003cp\u003e\u003cb\u003e5 Heritability and Repeatability 39\u003cbr\u003e\u003c\/b\u003e\u003ci\u003eGuilherme J. M. Rosa\u003c\/i\u003e\u003c\/p\u003e \u003cp\u003eIntroduction 39\u003c\/p\u003e \u003cp\u003eHeritability 39\u003c\/p\u003e \u003cp\u003eEstimation of heritability and variance components 40\u003c\/p\u003e \u003cp\u003ePrediction of breeding values and of response to selection 41\u003c\/p\u003e \u003cp\u003eRepeatability 41\u003c\/p\u003e \u003cp\u003eReferences 42\u003c\/p\u003e \u003cp\u003e\u003cb\u003e6 Applications of Statistics in Quantitative Traits 43\u003cbr\u003e\u003c\/b\u003e\u003ci\u003eHayrettin Okut\u003c\/i\u003e\u003c\/p\u003e \u003cp\u003ePopulation and sample 43\u003c\/p\u003e \u003cp\u003eDescriptive statistics 43\u003c\/p\u003e \u003cp\u003eGraphically examining the distribution of the data 47\u003c\/p\u003e \u003cp\u003eNormal distribution 49\u003c\/p\u003e \u003cp\u003eExploring relationships between variables 53\u003c\/p\u003e \u003cp\u003eSummary 59\u003c\/p\u003e \u003cp\u003eAppendix 6.1 62\u003c\/p\u003e \u003cp\u003eFurther reading 62\u003c\/p\u003e \u003cp\u003eReferences 62\u003c\/p\u003e \u003cp\u003eReview questions 63\u003c\/p\u003e \u003cp\u003e\u003cb\u003eSection 2: Applications of Genetics and Genomics to Livestock and Companion Animal Species 65\u003c\/b\u003e\u003c\/p\u003e \u003cp\u003e\u003cb\u003e7 Genetic Improvement of Beef Cattle 67\u003cbr\u003e\u003c\/b\u003e\u003ci\u003eMichael D. MacNeil\u003c\/i\u003e\u003c\/p\u003e \u003cp\u003eIntroduction 67\u003c\/p\u003e \u003cp\u003eSingle trait selection 67\u003c\/p\u003e \u003cp\u003eNational cattle evaluation 69\u003c\/p\u003e \u003cp\u003eMultiple trait selection 71\u003c\/p\u003e \u003cp\u003eSummary 71\u003c\/p\u003e \u003cp\u003eFurther reading 71\u003c\/p\u003e \u003cp\u003eReferences 72\u003c\/p\u003e \u003cp\u003e\u003cb\u003e8 Genetic Improvement in Sheep through Selection 73\u003cbr\u003e\u003c\/b\u003e\u003ci\u003eDavid L. Thomas\u003c\/i\u003e\u003c\/p\u003e \u003cp\u003eProducts from sheep 73\u003c\/p\u003e \u003cp\u003eSelection among breeds 73\u003c\/p\u003e \u003cp\u003eSelection within a breed or population and the Key Equation 73\u003c\/p\u003e \u003cp\u003eAdjustment for environmental effects 73\u003c\/p\u003e \u003cp\u003ePhenotypic selection 75\u003c\/p\u003e \u003cp\u003eEstimated breeding values (EBV) 75\u003c\/p\u003e \u003cp\u003eUsing multiple sources of information 76\u003c\/p\u003e \u003cp\u003eGenetic correlations 76\u003c\/p\u003e \u003cp\u003eSelection intensity 78\u003c\/p\u003e \u003cp\u003eGeneration interval (L) 79\u003c\/p\u003e \u003cp\u003ePredicting progress from selection 79\u003c\/p\u003e \u003cp\u003eNational genetic improvement programs 80\u003c\/p\u003e \u003cp\u003eSummary 81\u003c\/p\u003e \u003cp\u003eFurther reading 82\u003c\/p\u003e \u003cp\u003eReferences 82\u003c\/p\u003e \u003cp\u003eReview questions 82\u003c\/p\u003e \u003cp\u003e\u003cb\u003e9 Genetic Improvement Programs for Dairy Cattle 85\u003cbr\u003e\u003c\/b\u003e\u003ci\u003eKent Weigel\u003c\/i\u003e\u003c\/p\u003e \u003cp\u003eIntroduction 85\u003c\/p\u003e \u003cp\u003eData collection infrastructure 85\u003c\/p\u003e \u003cp\u003eEstimation of breeding values 87\u003c\/p\u003e \u003cp\u003eSelection for increased productivity 89\u003c\/p\u003e \u003cp\u003eSelection for functional traits 91\u003c\/p\u003e \u003cp\u003eSire selection 94\u003c\/p\u003e \u003cp\u003eSummary 94\u003c\/p\u003e \u003cp\u003eFurther reading 95\u003c\/p\u003e \u003cp\u003eReferences 95\u003c\/p\u003e \u003cp\u003eReview questions 96\u003c\/p\u003e \u003cp\u003e\u003cb\u003e10 Genetic and Genomic Improvement of Pigs 97\u003cbr\u003e\u003c\/b\u003e\u003ci\u003eMax F. Rothschild\u003c\/i\u003e\u003c\/p\u003e \u003cp\u003eIntroduction 97\u003c\/p\u003e \u003cp\u003eDomestication of swine and breed development 97\u003c\/p\u003e \u003cp\u003eMethods of selection and mating systems 98\u003c\/p\u003e \u003cp\u003eTraits of economic importance 99\u003c\/p\u003e \u003cp\u003eDevelopment of molecular genetic approaches 100\u003c\/p\u003e \u003cp\u003eQTL candidate genes and genetic improvement 100\u003c\/p\u003e \u003cp\u003eSequencing the pig genome 101\u003c\/p\u003e \u003cp\u003eGenomic selection 102\u003c\/p\u003e \u003cp\u003eDatabases 103\u003c\/p\u003e \u003cp\u003eCloning transgenics and breeding pigs as biological models 103\u003c\/p\u003e \u003cp\u003eFuture applications to genetic improvement 103\u003c\/p\u003e \u003cp\u003eAcknowledgments 104\u003c\/p\u003e \u003cp\u003eFurther reading 104\u003c\/p\u003e \u003cp\u003eReferences 104\u003c\/p\u003e \u003cp\u003eReview questions 105\u003c\/p\u003e \u003cp\u003e\u003cb\u003e11 Equine Genetics 107\u003cbr\u003e\u003c\/b\u003e\u003ci\u003eJennifer Minick Bormann\u003c\/i\u003e\u003c\/p\u003e \u003cp\u003eColor 107\u003c\/p\u003e \u003cp\u003eGenetic defects 110\u003c\/p\u003e \u003cp\u003eInbreeding and relationship 113\u003c\/p\u003e \u003cp\u003eSelection and improvement 114\u003c\/p\u003e \u003cp\u003eNew technologies 116\u003c\/p\u003e \u003cp\u003eFurther reading 117\u003c\/p\u003e \u003cp\u003eReferences 119\u003c\/p\u003e \u003cp\u003eReview questions 119\u003c\/p\u003e \u003cp\u003e\u003cb\u003e12 Genetics and Genomics of the Domestic Dog 121\u003cbr\u003e\u003c\/b\u003e\u003ci\u003eLeigh Anne Clark and Alison Starr-Moss\u003c\/i\u003e\u003c\/p\u003e \u003cp\u003eIntroduction to canine research 121\u003c\/p\u003e \u003cp\u003eThe dog genome 122\u003c\/p\u003e \u003cp\u003eUncovering the genetic basis of phenotypes 125\u003c\/p\u003e \u003cp\u003eFuture challenges 127\u003c\/p\u003e \u003cp\u003eSummary 128\u003c\/p\u003e \u003cp\u003eFurther reading 129\u003c\/p\u003e \u003cp\u003eReferences 130\u003c\/p\u003e \u003cp\u003eReview questions 130\u003c\/p\u003e \u003cp\u003e\u003cb\u003e13 The Sheep Genome 131\u003cbr\u003e\u003c\/b\u003e\u003ci\u003eNoelle E. Cockett and Chunhua Wu\u003c\/i\u003e\u003c\/p\u003e \u003cp\u003eInvestment in sheep genome research 131\u003c\/p\u003e \u003cp\u003eOverview of the sheep genome 131\u003c\/p\u003e \u003cp\u003eGenomic resources in sheep 131\u003c\/p\u003e \u003cp\u003eApplication of genomic resources 134\u003c\/p\u003e \u003cp\u003eSummary 134\u003c\/p\u003e \u003cp\u003eReferences 135\u003c\/p\u003e \u003cp\u003eReview questions 136\u003c\/p\u003e \u003cp\u003e\u003cb\u003e14 Goat Genetics and Genomic Progress 137\u003cbr\u003e\u003c\/b\u003e\u003ci\u003eMulumebet Worku\u003c\/i\u003e\u003c\/p\u003e \u003cp\u003eIntroduction 137\u003c\/p\u003e \u003cp\u003eGenetics and goat domestication 137\u003c\/p\u003e \u003cp\u003eTaxonomy 138\u003c\/p\u003e \u003cp\u003eGoat chromosome number and structure 138\u003c\/p\u003e \u003cp\u003ePatterns of inheritance 139\u003c\/p\u003e \u003cp\u003eQuantitative trail loci (QTL) 139\u003c\/p\u003e \u003cp\u003eProgress in goat genomics 139\u003c\/p\u003e \u003cp\u003eBiotechnologies and goat genetics 140\u003c\/p\u003e \u003cp\u003eSummary 140\u003c\/p\u003e \u003cp\u003eFurther reading 140\u003c\/p\u003e \u003cp\u003eReview questions 141\u003c\/p\u003e \u003cp\u003e\u003cb\u003eSection 3: Molecular Genetics of Production and Economically Important Traits 143\u003c\/b\u003e\u003c\/p\u003e \u003cp\u003e\u003cb\u003e15 Bioinformatics in Animal Genetics 145\u003cbr\u003e\u003c\/b\u003e\u003ci\u003eJosé A. Carrillo and Jiuzhou Song\u003c\/i\u003e\u003c\/p\u003e \u003cp\u003eIntroduction 145\u003c\/p\u003e \u003cp\u003eBioinformatics and animal genetics 145\u003c\/p\u003e \u003cp\u003eThe importance of bioinformatics in genomics research 146\u003c\/p\u003e \u003cp\u003eGene expression 148\u003c\/p\u003e \u003cp\u003eGene regulation 150\u003c\/p\u003e \u003cp\u003eEpigenetics 151\u003c\/p\u003e \u003cp\u003eGenomic data manipulation 151\u003c\/p\u003e \u003cp\u003eBioinformatics perspectives in animal genetics 153\u003c\/p\u003e \u003cp\u003eReferences 153\u003c\/p\u003e \u003cp\u003eReview questions 154\u003c\/p\u003e \u003cp\u003e\u003cb\u003e16 Genome-wide Association Studies in Pedigreed Populations 155\u003cbr\u003e\u003c\/b\u003e\u003ci\u003eDirk-Jan de Koning\u003c\/i\u003e\u003c\/p\u003e \u003cp\u003eIntroduction 155\u003c\/p\u003e \u003cp\u003eMethods and tools for GWAS in pedigreed populations 159\u003c\/p\u003e \u003cp\u003eThings to remember about analysis 160\u003c\/p\u003e \u003cp\u003eWhat did we miss? 160\u003c\/p\u003e \u003cp\u003eAcknowledgments 162\u003c\/p\u003e \u003cp\u003eReferences 162\u003c\/p\u003e \u003cp\u003e\u003cb\u003e17 Molecular Genetics Techniques and High Throughput Technologies 163\u003cbr\u003e\u003c\/b\u003e\u003ci\u003eWen Huang\u003c\/i\u003e\u003c\/p\u003e \u003cp\u003eCentral dogma of molecular biology 163\u003c\/p\u003e \u003cp\u003eReview of properties of nucleic acids 163\u003c\/p\u003e \u003cp\u003ePurifi cation of nucleic acids from cells 164\u003c\/p\u003e \u003cp\u003eDetermining the quantity and purity of nucleic acids 165\u003c\/p\u003e \u003cp\u003ePolymerase chain reaction (PCR) 166\u003c\/p\u003e \u003cp\u003eDetermining the identity of DNA 167\u003c\/p\u003e \u003cp\u003eConcept of parallelization and high throughput assays 168\u003c\/p\u003e \u003cp\u003eNext generation sequencing technology 171\u003c\/p\u003e \u003cp\u003eSummary 174\u003c\/p\u003e \u003cp\u003eFurther reading 174\u003c\/p\u003e \u003cp\u003eReview questions 174\u003c\/p\u003e \u003cp\u003e\u003cb\u003e18 Single Genes in Animal Breeding 177\u003cbr\u003e\u003c\/b\u003e\u003ci\u003eBrian W. Kirkpatrick\u003c\/i\u003e\u003c\/p\u003e \u003cp\u003eIntroduction 177\u003c\/p\u003e \u003cp\u003eMapping and identifying single genes 177\u003c\/p\u003e \u003cp\u003eWhat types of DNA sequence alterations create single gene effects? 180\u003c\/p\u003e \u003cp\u003eExamples of single genes in animal breeding 181\u003c\/p\u003e \u003cp\u003eSummary 185\u003c\/p\u003e \u003cp\u003eReferences 185\u003c\/p\u003e \u003cp\u003eReview questions 186\u003c\/p\u003e \u003cp\u003e\u003cb\u003e19 Molecular Genetics of Coat Color: It is more than Just Skin Deep 187\u003cbr\u003e\u003c\/b\u003e\u003ci\u003eSamantha Brooks\u003c\/i\u003e\u003c\/p\u003e \u003cp\u003eIntroduction 187\u003c\/p\u003e \u003cp\u003ePathways of melanocyte migration and differentiation from the neural crest 187\u003c\/p\u003e \u003cp\u003eMelanocyte signaling and regulation 188\u003c\/p\u003e \u003cp\u003eMelanin production and transport 190\u003c\/p\u003e \u003cp\u003eConclusions 192\u003c\/p\u003e \u003cp\u003eSummary 192\u003c\/p\u003e \u003cp\u003eKey terms 192\u003c\/p\u003e \u003cp\u003eReferences 193\u003c\/p\u003e \u003cp\u003eReview questions 195\u003c\/p\u003e \u003cp\u003e\u003cb\u003e20 Molecular Genetics-Nutrition Interactions in Ruminant Fatty Acid Metabolism and Meat Quality 197\u003cbr\u003e\u003c\/b\u003e\u003ci\u003eAduli E.O. Malau-Aduli and Benjamin W.B. Holman\u003c\/i\u003e\u003c\/p\u003e \u003cp\u003eIntroduction 197\u003c\/p\u003e \u003cp\u003eGenetics-nutrition interactions in ruminants 197\u003c\/p\u003e \u003cp\u003eEducating Australian undergraduate students in molecular genetics-nutrition interactions in ruminants 198\u003c\/p\u003e \u003cp\u003eReview of fatty acids and their manipulation metabolism, and effect on quality in ruminants 200\u003c\/p\u003e \u003cp\u003eConcluding remarks 205\u003c\/p\u003e \u003cp\u003eAppendix 20.1: Fats and beef quality laboratory practicals 206\u003c\/p\u003e \u003cp\u003eAppendix 20.2: Sensory evaluation of meat quality in grain-fed versus grass-fed beef 206\u003c\/p\u003e \u003cp\u003eAppendix 20.3: Total lipid extraction from a beef cut for fatty acid analysis 206\u003c\/p\u003e \u003cp\u003eAppendix 20.4: Molecular genetics laboratory practical 207 References 212\u003c\/p\u003e \u003cp\u003e\u003cb\u003e21 Nutritional Epigenomics 215\u003cbr\u003e\u003c\/b\u003e\u003ci\u003eCongjun Li\u003c\/i\u003e\u003c\/p\u003e \u003cp\u003eIntroduction 215\u003c\/p\u003e \u003cp\u003eEpigenomic machinery and gene regulation 216\u003c\/p\u003e \u003cp\u003eNutrients and histone modification 219\u003c\/p\u003e \u003cp\u003eNutrients and epigenetics in bovine cells: one definative example of the nutrient-epigenetic-phenotype relationship 221\u003c\/p\u003e \u003cp\u003eSummary 224\u003c\/p\u003e \u003cp\u003eReferences 224\u003c\/p\u003e \u003cp\u003eReview questions 225\u003c\/p\u003e \u003cp\u003e\u003cb\u003eSection 4: Genetics of Embryo Development and Fertility 227\u003c\/b\u003e\u003c\/p\u003e \u003cp\u003e\u003cb\u003e22 Genomics of Sex Determination and Dosage Compensation 229\u003cbr\u003e\u003c\/b\u003e\u003ci\u003eJenifer Cruickshank and Christopher H. Chandler\u003c\/i\u003e\u003c\/p\u003e \u003cp\u003eGenotypic sex determination (GSD) 229\u003c\/p\u003e \u003cp\u003eEnvironmental sex determination (ESD) 232\u003c\/p\u003e \u003cp\u003eDosage compensation in mammals: X chromosome inactivation 232\u003c\/p\u003e \u003cp\u003eActivity patterns of sex chromosomes during gametogenesis 233\u003c\/p\u003e \u003cp\u003eEscape from X inactivation 234\u003c\/p\u003e \u003cp\u003eAbnormalities in chromosomal sex 235\u003c\/p\u003e \u003cp\u003eSex reversal 235\u003c\/p\u003e \u003cp\u003eSummary 236\u003c\/p\u003e \u003cp\u003eFurther reading 236\u003c\/p\u003e \u003cp\u003eReview questions 237\u003c\/p\u003e \u003cp\u003e\u003cb\u003e23 Functional Genomics of Mammalian Gametes and Preimplantation Embryos 239\u003cbr\u003e\u003c\/b\u003e\u003ci\u003eŞule Doğan Aruna Govindaraju Elizabeth A. Crate, and Erdoğan Memili\u003c\/i\u003e\u003c\/p\u003e \u003cp\u003eIntroduction 239\u003c\/p\u003e \u003cp\u003eGamete and embryo development 239\u003c\/p\u003e \u003cp\u003eTranscriptomics 242\u003c\/p\u003e \u003cp\u003eProteomics 248\u003c\/p\u003e \u003cp\u003eSystems biology 251\u003c\/p\u003e \u003cp\u003eConclusion 253\u003c\/p\u003e \u003cp\u003eFurther reading 253\u003c\/p\u003e \u003cp\u003eReferences 253\u003c\/p\u003e \u003cp\u003e\u003cb\u003e24 The Genetics of \u003ci\u003eIn Vitro \u003c\/i\u003eProduced Embryos 257\u003cbr\u003e\u003c\/b\u003e\u003ci\u003eAshley Driver\u003c\/i\u003e\u003c\/p\u003e \u003cp\u003e\u003ci\u003eIn vitro \u003c\/i\u003eproduction: from livestock to humans 257\u003c\/p\u003e \u003cp\u003eUnlocking developmentally important genes in the pre-implantation embryo 258\u003c\/p\u003e \u003cp\u003eIVP: potential source of genetic alteration? 259\u003c\/p\u003e \u003cp\u003ePGD: genetic screening and human embryos 259\u003c\/p\u003e \u003cp\u003eScreening the embryo: to infinity and beyond? 260\u003c\/p\u003e \u003cp\u003eEmbryogenetics: what’s next? 260\u003c\/p\u003e \u003cp\u003eSummary 260\u003c\/p\u003e \u003cp\u003eKey terms 260\u003c\/p\u003e \u003cp\u003eReferences 261\u003c\/p\u003e \u003cp\u003eReview questions 262\u003c\/p\u003e \u003cp\u003eSupplementary videos 262\u003c\/p\u003e \u003cp\u003e\u003cb\u003eSection 5: Genetics of Animal Health and Biotechnology 263\u003c\/b\u003e\u003c\/p\u003e \u003cp\u003e\u003cb\u003e25 Understanding the Major Histocompatibility Complex and Immunoglobulin Genes 265\u003cbr\u003e\u003c\/b\u003e\u003ci\u003eMichael G. Gonda\u003c\/i\u003e\u003c\/p\u003e \u003cp\u003eIntroduction 265\u003c\/p\u003e \u003cp\u003eOverview of the immune system 265\u003c\/p\u003e \u003cp\u003eThe major histocompatibility complex loci 267\u003c\/p\u003e \u003cp\u003eImmunoglobulin loci 268\u003c\/p\u003e \u003cp\u003eSummary 272\u003c\/p\u003e \u003cp\u003eKey terms 273\u003c\/p\u003e \u003cp\u003eFurther reading and references 274\u003c\/p\u003e \u003cp\u003eReview questions 274\u003c\/p\u003e \u003cp\u003e\u003cb\u003e26 Livestock and Companion Animal Genetics: Genetics of Infectious Disease Susceptibility 275\u003cbr\u003e\u003c\/b\u003e\u003ci\u003eMichael G. Gonda\u003c\/i\u003e\u003c\/p\u003e \u003cp\u003eIntroduction 275\u003c\/p\u003e \u003cp\u003eWhy is studying the genetics of disease susceptibility important? 275\u003c\/p\u003e \u003cp\u003ePresent applications of genetic selection tools for predicting disease susceptibility 276\u003c\/p\u003e \u003cp\u003eCurrent research into genetic selection for livestock health 279\u003c\/p\u003e \u003cp\u003eChallenges faced when studying the genetics of disease resistance in livestock 280\u003c\/p\u003e \u003cp\u003eShould we select for increased disease resistance? 281\u003c\/p\u003e \u003cp\u003eSummary 281\u003c\/p\u003e \u003cp\u003eKey terms 281\u003c\/p\u003e \u003cp\u003eFurther reading 282\u003c\/p\u003e \u003cp\u003eReview questions 282\u003c\/p\u003e \u003cp\u003e\u003cb\u003e27 Animal Genetics and Welfare 283\u003cbr\u003e\u003c\/b\u003e\u003ci\u003eAmin A. Fadl and Mark E. Cook\u003c\/i\u003e\u003c\/p\u003e \u003cp\u003eIntroduction 283\u003c\/p\u003e \u003cp\u003eA continued need for genetic improvements and knowledge 283\u003c\/p\u003e \u003cp\u003eWelfare 284\u003c\/p\u003e \u003cp\u003eGenetic advancement and animal welfare 284\u003c\/p\u003e \u003cp\u003eGenetic selection that adversely affects farmed animal welfare 286\u003c\/p\u003e \u003cp\u003eSummary 287\u003c\/p\u003e \u003cp\u003eReferences 287\u003c\/p\u003e \u003cp\u003eReview questions 288\u003c\/p\u003e \u003cp\u003e\u003cb\u003e28 Animal Biotechnology: Scientific Regulatory and Public Acceptance Issues Associated with Cloned and Genetically Engineered Animals 289\u003cbr\u003e\u003c\/b\u003e\u003ci\u003eAlison L. Van Eenennaam\u003c\/i\u003e\u003c\/p\u003e \u003cp\u003eWhat is animal biotechnology? 289\u003c\/p\u003e \u003cp\u003eCloning 290\u003c\/p\u003e \u003cp\u003eGenetic engineering 293\u003c\/p\u003e \u003cp\u003eEthical moral and animal welfare concerns 297\u003c\/p\u003e \u003cp\u003eSummary 299\u003c\/p\u003e \u003cp\u003eFurther reading 300\u003c\/p\u003e \u003cp\u003eReferences 300\u003c\/p\u003e \u003cp\u003eReview questions 301\u003c\/p\u003e \u003cp\u003e\u003cb\u003e29 Intellectual Property Rights and Animal Genetic Resources 303\u003cbr\u003e\u003c\/b\u003e\u003ci\u003eJennifer Long and Max F. Rothschild\u003c\/i\u003e\u003c\/p\u003e \u003cp\u003eIntroduction 303\u003c\/p\u003e \u003cp\u003eOld M\/cDonald’s Farm meets Dolly (and her lawyer) 303\u003c\/p\u003e \u003cp\u003eWhat is intellectual property? 303\u003c\/p\u003e \u003cp\u003eForms of intellectual property 303\u003c\/p\u003e \u003cp\u003eHere a patent there (not) a patent 304\u003c\/p\u003e \u003cp\u003eForms of payment or remuneration 305\u003c\/p\u003e \u003cp\u003eCase studies 306\u003c\/p\u003e \u003cp\u003eE-I-E-I-O: The alphabet soup of domestic and international issues 307\u003c\/p\u003e \u003cp\u003ePublic sector research and IP – domestic and international 307\u003c\/p\u003e \u003cp\u003eAccess to animal genetic resources 307\u003c\/p\u003e \u003cp\u003eSummary 308\u003c\/p\u003e \u003cp\u003eFurther reading 308\u003c\/p\u003e \u003cp\u003eReferences 308\u003c\/p\u003e \u003cp\u003eReview questions 309\u003c\/p\u003e \u003cp\u003eIndex 311\u003c\/p\u003e  \u003cp\u003e\u003cstrong\u003eHasan Khatib\u003c\/strong\u003e is an Associate Professor in the Department of Dairy Science at the University of Wisconsin-Madison. Dr. Khatib has taught a variety of undergraduate and graduate courses on animal breeding and genetics. He is also the lead editor of \u003cem\u003eLivestock Epigenetics\u003c\/em\u003e published by Wiley in 2012.\u003c\/p\u003e","brand":"Wiley-Blackwell","offers":[{"title":"Default Title","offer_id":47989646950629,"sku":"NP9781118677407","price":89.5,"currency_code":"USD","in_stock":false}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/1842\/7735\/files\/9781118677407.jpg?v=1761784945","url":"https:\/\/k12savings.com\/es\/products\/molecular-and-quantitative-animal-genetics-isbn-9781118677407","provider":"K12savings","version":"1.0","type":"link"}