Modern Conformational Analysis

Most books on organic conformational deal with sterochemistry, while neglecting the spatial structure of organic molecules, especially the unusual ones. This ambitious monograph presents a global view of organic structure and conformational analysis in a very readable style. The author's fascination with the beauty and variety of shapes of organic molecules comes through in her description of the importance of molecular organization in organic chemical and biological systems, the quantum foundations of molecular spatial structure, molecular symmetry, chiralty and physical methods for studying molecular geometry. She provides ample bases for the new trends in organic conformational chemistry, including the application of Computer Assisted Molecular Design (CAMD) to organic synthesis.Viele Bücher über organische Zusammensetzungen behandeln die Stereochemie, schenken aber der räumlichen Struktur der organischen Moleküle, vor allem der weniger gebräuchlichen, kaum Beachtung. Diese Monographie stellt nun ein umfassendes Werk zur organischen Struktur und der Konformationsanalyse dar. Das Interesse des Autors an der Formenvielfalt der organischen Moleküle spiegelt sich besonders intensiv in der Betrachtung der Molekülordnung wider, die in organisch chemischen und biologischen Systemen von großer Bedeutung ist. Der neue Band in der Reihe 'Methods in Stereochemical Analysis' stellt vor allem diese Bedeutung der Molekülgestalt und die Einwirkung theoretischer Studien und synthetischer Chemie zu diesem Themenkomplex in den Vordergrund. Molecular Symmetry.

Chirality and its Importance in Nature: Cahn, Ingold, and Prelog Classification of Chirality and its Modification.

Quantum Chemistry and Molecular Mechanics: Theoretical Foundation of Molecule Spatial Structure.

Physical Methods as a Source of Information on the Values of Bond Lengths and Angles in Organic Molecules.

Nonstandard Systems, the Purposes of Studying Them, Mutual Interaction Between Theory and Synthetic Chemistry.

Molecular Modeling: Computer Assisted Molecular Design (CAMD).

Index. From the Contents:
Molecular symmetry/
Chirality and its importance in nature;
Chan, Ingold and Prelog
classification of chirality and its modification/
Quantum chemistry and molecular mechanics -
theoretical foundations of molecular spatial structure/
Physical methods as a source of
information on the values of bond lengths and angles in organic molecules/
Spatial structure of
standard organic molecules/
Nonstandard systems, the purposes of studying them, mutual
interaction between theory and synthetic chemistry/
Molecular modelling

Helena Dodziuk is a professor working at the Physical Chemistry Institute of the Polish Academy of Sciences. She is interested in conformational analysis of hydrocarbons, classification of chirality, NMR spectra and structure of cyclodextrin complexes, endohedral fullerene complexes and carbon nanotubes. She has written more than 70 publications, several reviews and two books.