Mitochondrial Research in Translational Medicine, Volume 1201

This volume features the proceedings of the In the 6th Asian Society for Mitchondrial Research and Medicine and highlights recent advances in mitochondria research. The contributions focus on mitochondrial research in translational medicine and cover virtually every aspect of mitochondrial dynamics, mitochondrial function and dysfunction, free radical biology related to mitochondrial dysfunction, cell apoptosis and autophagy, and disease mechanisms associated with aging, neurodegeneration, mitochondrial disease, metabolic disease, and cancer.

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Glycoxidative stress-induced mitophagy modulates mitochondrial fates

Neuroprotective mechanisms of brain-derived neurotrophic factor against 3-nitropropionic acid toxicity: therapeutic implications for Huntington's disease

Advantages and considerations in the confirmation of mitochondrial DNA mutations by denaturing HPLC and pyrosequencing Physiological functions of mitochondrial fusion

Evaluating mitochondrial DNA in cancer occurrence and development

Dynamic regulation of mitochondrial fission through modification of the dynamin-related protein Drp1

A novel function of mtDNA: its involvement in metastasis

The NADH-fumarate reductase system, a novel mitochondrial energy metabolism, is a new target for anticancer therapy in tumor microenvironments

Bioenergetics and cell death

A role for the CISD2 gene in lifespan control and human disease

Roles of GSK3 in metabolic shift toward abnormal anabolism in cell senescence

Manganese superoxide dismutase versus p53: the mitochondrial center. Role of autophagy in diabetes and mitochondria

Mitochondrial Q cycle-derived superoxide and chemiosmotic bioenergetics

Animal and human studies with the mitochondria-targeted antioxidant MitoQ

MELAS and l-arginine therapy: pathophysiology of stroke-like episodes

Metabolic analysis of 13C-labeled pyruvate for noninvasive assessment of mitochondrial function

Redefining the role of mitochondria in exercise: a dynamic remodeling

RelB regulates manganese superoxide dismutase gene and resistance to ionizing radiation of prostate cancer cells

Functional effects of cancer mitochondria on energy metabolism and tumorigenesis: utility of transmitochondrial cybrids

Mitochondrial respiratory dysfunction-elicited oxidative stress and posttranslational protein modification in mitochondrial diseases

Mitochondrial dysfunction in insulin insensitivity: implication of mitochondrial role in type 2 diabetes

Persistent organic pollutants, mitochondrial dysfunction, and metabolic syndrome

Potential therapeutic applications of tetrahydrobiopterin: from inherited hyperphenylalaninemia to mitochondrial diseases

Oxidative stress caused by mitochondrial calcium overload

"This is an excellent compilation of important topics related to diseases resulting from mitochondrial dysfunction." (Doody's, 12 August 2011)

Yau-Huei Wei is the editor of Mitochondrial Research in Translational Medicine, Volume 1201, published by Wiley. Chii-Ruey Tzeng is the editor of Mitochondrial Research in Translational Medicine, Volume 1201, published by Wiley.