{"product_id":"metabolic-syndrome-and-neurological-disorders-isbn-9781118395271","title":"Metabolic Syndrome and Neurological Disorders","description":"\u003cp\u003e\u003ci\u003eMetabolic Syndrome and Neurological Disorders\u003c\/i\u003e brings together information on the cluster of common pathologies which cause metabolic syndrome - abdominal obesity linked to an excess of visceral fat, insulin resistance, dyslipidemia and hypertension - to provide a comprehensive and cutting edge exploration of the link between metabolic syndrome and neurological disorders.\u003c\/p\u003e \u003cp\u003eMetabolic syndrome is recognized to play a role in neurological disorders such as stroke, Alzheimer's disease, and depression. For the first time in book form, Metabolic Syndrome and Neurological Disorders covers the molecular mechanisms thought to underlie this mirror relationship, as well as how lifestyle and other factors such as oxidative stress and inflammation may play a role in the disease. Grounded in a series of epidemiological studies of metabolic-cognitive syndrome, this book will be a valuable reference for researchers, dietitians, nutritionists, and physicians.\u003c\/p\u003e  \u003cp\u003e\u003cb\u003eForeword\u003c\/b\u003e \u003ci\u003eMark P. Mattson\u003c\/i\u003e xi\u003c\/p\u003e \u003cp\u003e\u003cb\u003ePreface\u003c\/b\u003e \u003ci\u003eTahira Farooqui and Akhlaq A. Farooqui\u003c\/i\u003e xiii\u003c\/p\u003e \u003cp\u003e\u003cb\u003eAcknowledgments\u003c\/b\u003e \u003ci\u003eTahira Farooqui and Akhlaq A. Farooqui\u003c\/i\u003e xv\u003c\/p\u003e \u003cp\u003e\u003cb\u003eContributors xvii\u003c\/b\u003e\u003c\/p\u003e \u003cp\u003e\u003cb\u003e1 Insulin Resistance and Metabolic Failure Underlie Alzheimer Disease 1\u003c\/b\u003e\u003cbr\u003e \u003ci\u003eSuzanne M. de la Monte and Ming Tong\u003c\/i\u003e\u003c\/p\u003e \u003cp\u003e\u003cb\u003e2 Insulin Receptor and the Pathophysiology of Alzheimer Disease 31\u003c\/b\u003e\u003cbr\u003e \u003ci\u003eJohanna Zemva and Markus Schubert\u003c\/i\u003e\u003c\/p\u003e \u003cp\u003e\u003cb\u003e3 Contribution of Insulin Resistance in Pathogenesis of Alzheimer Disease 51\u003c\/b\u003e\u003cbr\u003e \u003ci\u003eAdnan Erol\u003c\/i\u003e\u003c\/p\u003e \u003cp\u003e\u003cb\u003e4 Insulin–Leptin Signaling in the Brain 75\u003c\/b\u003e\u003cbr\u003e \u003ci\u003eVicente Barrios, Emma Burgos-Ramos, and Jes´us Argente\u003c\/i\u003e\u003c\/p\u003e \u003cp\u003e\u003cb\u003e5 The Janus Face of Insulin in Brain 85\u003c\/b\u003e\u003cbr\u003e \u003ci\u003eAna Duarte, Emanuel Candeias, S´onia C. Correia, Renato X. Santos, Cristina Carvalho, Susana Cardoso, Ana I. Pl´acido, Maria S. Santos, Catarina R. Oliveira, and Paula I. Moreira\u003c\/i\u003e\u003c\/p\u003e \u003cp\u003e\u003cb\u003e6 Modulation of Cognition by Insulin and Aging: Implications for Alzheimer Disease 115\u003c\/b\u003e\u003cbr\u003e \u003ci\u003eMaite Solas and Maria J. Ram´ýrez\u003c\/i\u003e\u003c\/p\u003e \u003cp\u003e\u003cb\u003e7 Contribution of Phospholipid, Sphingolipids, and Cholesterol-Derived Lipid Mediators in the Pathogenesis of Metabolic Syndrome and Neurological Disorders 137\u003c\/b\u003e\u003cbr\u003e \u003ci\u003eAkhlaq A. Farooqui and Tahira Farooqui\u003c\/i\u003e\u003c\/p\u003e \u003cp\u003e\u003cb\u003e8 Lipids, Cholesterol, and Oxidized Cholesterol in Alzheimer Amyloid Beta-Mediated\u003c\/b\u003e\u003cbr\u003e \u003cb\u003eNeurotoxicity 163\u003c\/b\u003e\u003cbr\u003e \u003ci\u003eMun’delanji C. Vestergaard, Masamune Morita, Tsutomu Hamada, and Masahiro Takagi\u003c\/i\u003e\u003c\/p\u003e \u003cp\u003e\u003cb\u003e9 Of Sound Mind and Body: Dietary Lifestyles, Promotion of Healthy Brain Aging, and Prevention of Dementia in Healthy Individuals 179\u003c\/b\u003e\u003cbr\u003e \u003ci\u003eGiulio Maria Pasinetti, Amanda Bilski, Lap Ho, Jun Wang, Mario Ferruzzi, Masahito Yamada, Kenjiro Ono, and Salvatore Mannino\u003c\/i\u003e\u003c\/p\u003e \u003cp\u003e\u003cb\u003e10 Metabolic Syndrome as an Independent Risk Factor of Silent Brain Infarction 191\u003c\/b\u003e\u003cbr\u003e \u003ci\u003eJae-Sung Lim and Hyung-Min Kwon\u003c\/i\u003e\u003c\/p\u003e \u003cp\u003e\u003cb\u003e11 Neurochemical Linkage Among Metabolic Syndrome, Alzheimer Disease, and Depression 197\u003c\/b\u003e\u003cbr\u003e \u003ci\u003eUndurti N. Das\u003c\/i\u003e\u003c\/p\u003e \u003cp\u003e\u003cb\u003e12 Alterations in the Endocannabinoid System as a Link Between Unbalanced Energy Homeostasis, Neuroinflammation, and Neurological and Neuropsychiatric Disorders 219\u003c\/b\u003e\u003cbr\u003e \u003ci\u003eTiziana Bisogno and Vincenzo Di Marzo\u003c\/i\u003e\u003c\/p\u003e \u003cp\u003e\u003cb\u003e13 Metabolic Syndrome, Alzheimer Disease, Schizophrenia, and Depression: Role for Leptin, Melatonin, Kynurenine Pathways, and Neuropeptides 235\u003c\/b\u003e\u003cbr\u003e \u003ci\u003eGeorge Anderson and Michael Maes\u003c\/i\u003e\u003c\/p\u003e \u003cp\u003e\u003cb\u003e14 Binge Eating and Metabolic Syndrome 249\u003c\/b\u003e\u003cbr\u003e \u003ci\u003eIgnacio J´auregui-Lobera\u003c\/i\u003e\u003c\/p\u003e \u003cp\u003e\u003cb\u003e15 Phytochemical Principles in the Traditional Indian System of Medicine Used for the Management of Metabolic Syndrome 261\u003c\/b\u003e\u003cbr\u003e \u003ci\u003eSyed Ibrahim Rizvi and Neetu Mishra\u003c\/i\u003e\u003c\/p\u003e \u003cp\u003e\u003cb\u003e16 Oxidative Stress and Obesity: Their Impact on Metabolic Syndrome 275\u003c\/b\u003e\u003cbr\u003e \u003ci\u003eMorihiro Matsuda and Iichiro Shimomura\u003c\/i\u003e\u003c\/p\u003e \u003cp\u003e\u003cb\u003e17 The Relationship Among Obesity, Inflammation, and Insulin Resistance 283\u003c\/b\u003e\u003cbr\u003e \u003ci\u003eJean-Philippe Bastard and Bruno F`eve\u003c\/i\u003e\u003c\/p\u003e \u003cp\u003e\u003cb\u003e18 Involvement of Adipocytokines in Pathogenesis of Insulin Resistance, Obesity, and Metabolic Syndrome 297\u003c\/b\u003e\u003cbr\u003e \u003ci\u003eHardik Gandhi and Ramachandran Balaraman\u003c\/i\u003e\u003c\/p\u003e \u003cp\u003e\u003cb\u003e19 Obesity, Inflammation, and Vascular Disease: Novel Insight in the Role of Adipose Tissue 311\u003c\/b\u003e\u003cbr\u003e \u003ci\u003ePaolo Calabro, Enrica Golia, Valeria Maddaloni, Giuseppe Limongelli, Brunella Ziello, Fabio Fimiani, Ilaria Jane Romano, Mario Crisci, Maria Giovanna Russo, Edward T.H. Yeh, and Raffaele Calabro\u003c\/i\u003e\u003c\/p\u003e \u003cp\u003e\u003cb\u003e20 Is Diabetes a Risk Factor for Parkinson Disease? 327\u003c\/b\u003e\u003cbr\u003e \u003ci\u003eAkhlaq A. Farooqui and Tahira Farooqui\u003c\/i\u003e\u003c\/p\u003e \u003cp\u003e\u003cb\u003e21 Role of Iron in the Pathogenesis of Diabetes and Metabolic Syndrome 335\u003c\/b\u003e\u003cbr\u003e \u003ci\u003eLu Cai\u003c\/i\u003e\u003c\/p\u003e \u003cp\u003e\u003cb\u003e22 Contributions of AMP Kinase to the Pathogenesis of Type 2 Diabetes and Neurodegenerative Diseases 363\u003c\/b\u003e\u003cbr\u003e \u003ci\u003eMohamed Kodiha, Hicham Mahboubi, and Ursula Stochaj\u003c\/i\u003e\u003c\/p\u003e \u003cp\u003e\u003cb\u003e23 A_ Deposition, Insulin Signaling, and Tau Phosphorylation in Animal Models of Alzheimer Disease and Diabetes 383\u003c\/b\u003e\u003cbr\u003e \u003ci\u003eNaoyuki Sato and Ryuichi Morishita\u003c\/i\u003e\u003c\/p\u003e \u003cp\u003e\u003cb\u003e24 In Vivo Evidence of the Convergence of Type 2 Diabetes and Alzheimer Disease 395\u003c\/b\u003e\u003cbr\u003e \u003ci\u003eSun Ah Park\u003c\/i\u003e\u003c\/p\u003e \u003cp\u003e\u003cb\u003e25 Metabolic Syndrome and its Impact on Cardiovascular Disease 409\u003c\/b\u003e\u003cbr\u003e \u003ci\u003eJohn A. Larry\u003c\/i\u003e\u003c\/p\u003e \u003cp\u003e\u003cb\u003e26 Contribution of Inflammation, Adiponectin, and Obesity in Cardiovascular Diseases 423\u003c\/b\u003e\u003cbr\u003e \u003ci\u003eHarald Mangge and Gunter Almer\u003c\/i\u003e\u003c\/p\u003e \u003cp\u003e\u003cb\u003e27 Brain and Cardiovascular Diseases: Molecular Aspects 439\u003c\/b\u003e\u003cbr\u003e \u003ci\u003eEwa Szczepanska-Sadowska\u003c\/i\u003e\u003c\/p\u003e \u003cp\u003e\u003cb\u003e28 Molecular Aspects of Dietary–Exercise Regimen for the Prevention of Metabolic Syndrome 461\u003c\/b\u003e\u003cbr\u003e \u003ci\u003eWataru Aoi\u003c\/i\u003e\u003c\/p\u003e \u003cp\u003e\u003cb\u003e29 Ghrelin, Lipid Metabolism, and Metabolic Syndrome 475\u003c\/b\u003e\u003cbr\u003e \u003ci\u003ePablo B. Mart´ýnez de Morentin, Sulay Tovar, Rub´en Nogueiras, Miguel L´opez, and Carlos Di´eguez\u003c\/i\u003e\u003c\/p\u003e \u003cp\u003e\u003cb\u003e30 Leptin and Cognitive Function 485\u003c\/b\u003e\u003cbr\u003e \u003ci\u003eJenni Harvey\u003c\/i\u003e\u003c\/p\u003e \u003cp\u003e\u003cb\u003e31 Fructose, Sugar Consumption, and Metabolic Diseases 501\u003c\/b\u003e\u003cbr\u003e \u003ci\u003eVirgile Lecoultre and Luc Tappy\u003c\/i\u003e\u003c\/p\u003e \u003cp\u003e\u003cb\u003e32 Inflammation-Mediated Cognitive and Emotional Alterations in Experimental Models of Metabolic Syndrome 515\u003c\/b\u003e\u003cbr\u003e \u003ci\u003eNathalie Castanon and Sophie Lay´e\u003c\/i\u003e\u003cbr\u003e \u003cbr\u003e \u003cb\u003e33 Summary and Perspective 529\u003c\/b\u003e\u003cbr\u003e \u003ci\u003eTahira Farooqui and Akhlaq A. Farooqui\u003c\/i\u003e\u003c\/p\u003e \u003cp\u003e\u003ci\u003eIndex 539\u003c\/i\u003e\u003c\/p\u003e \u003cp\u003e\u003ci\u003eColor plate section is located between pages 196 and 197.\u003c\/i\u003e\u003c\/p\u003e  \u003cb\u003eAKHLAQ FAROOQUI\u003c\/b\u003e is an Adjunct Associate Professor of Medical Biochemistry at Ohio State University. He is author of over 180 peer-reviewed research articles, and author\/editor of eight books and an expert in fields of glycerophospholipid metabolism, excitotoxicity, bioactive ether lipids, and phospholipases A2 in brain.  \u003cp\u003e\u003cb\u003eTAHIRA FAROOQUI\u003c\/b\u003e is a Research Scientist in the Department of Entomology at Ohio State University. She is the author of 40 peer-reviewed research articles and several monographs and an expert on glycerophospholipid and sphingolipid metabolism, biogenic amines, and neural plasticity.\u003c\/p\u003e  \u003cp\u003eMetabolic syndrome is a recognized suite of biological risk factors that increase the likelihood of developing long-term health problems including a wide range of neurological disorders. \u003ci\u003eMetabolic Syndrome and Neurological Disorders\u003c\/i\u003e brings together information on the cluster of common pathologies which cause metabolic syndrome - obesity, insulin resistance, and hypertension - to provide a comprehensive and cutting edge exploration of the link between metabolic syndrome and neurological disorders.\u003c\/p\u003e \u003cp\u003e\u003ci\u003eMetabolic Syndrome and Neurological Disorders\u003c\/i\u003e covers the molecular mechanisms thought to connect metabolic syndrome with neurological disorders ranging from stroke to neurodegenerative diseases. Chapters also look at how other factors such as oxidative stress and inflammation may play a role in disease development.\u003c\/p\u003e \u003cp\u003eGrounded in a series of epidemiological studies of metabolic-cognitive syndrome, \u003ci\u003eMetabolic Syndrome and Neurological Disorders\u003c\/i\u003e is a valuable reference for researchers and clinicians in the field.\u003cbr\u003e \u003cbr\u003e \u003c\/p\u003e \u003cul\u003e \u003cli\u003eComprehensive coverage of the molecular mechanisms behind the link between metabolic syndrome and stroke, Alzheimer disease, and depression\u003c\/li\u003e \u003cli\u003eTimely investigation of a health issue which will be of increasing importance given the aging of the world's population \u003c\/li\u003e \u003cli\u003eWritten by leaders in the field of metabolic syndrome\u003c\/li\u003e \u003cli\u003eUnique, accessible exploration of a topic with relevance for a wide variety of disciplines, including neuroscientists, pharmacologists, and clinicians\u003c\/li\u003e \u003c\/ul\u003e","brand":"Wiley-Blackwell","offers":[{"title":"Default Title","offer_id":47989610316005,"sku":"NP9781118395271","price":238.95,"currency_code":"USD","in_stock":false}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/1842\/7735\/files\/9781118395271.jpg?v=1761784800","url":"https:\/\/k12savings.com\/es\/products\/metabolic-syndrome-and-neurological-disorders-isbn-9781118395271","provider":"K12savings","version":"1.0","type":"link"}