{"product_id":"meta-analysis-of-controlled-clinical-trials-isbn-9780471983705","title":"Meta-Analysis of Controlled Clinical Trials","description":"\u003cp\u003eOver the last twenty years there has been a dramatic upsurge in the application of meta-analysis to medical research. This has mainly been due to greater emphasis on evidence-based medicine and the need for reliable summaries of the vast and expanding volume of clinical research. At the same time there have been great strides in the development and refinement of the associated statistical methodology. This book describes the planning, conduct and reporting of a meta-analysis as applied to a series of randomized controlled clinical trials.\u003c\/p\u003e \u003cul\u003e \u003cli\u003eThe various approaches are presented within a general unified framework.\u003c\/li\u003e \u003cli\u003eMeta-analysis techniques are described in detail, from their theoretical development through to practical implementation.\u003c\/li\u003e \u003cli\u003eEach topic discussed is supported by detailed worked examples.\u003c\/li\u003e \u003cli\u003eA comparison of fixed and random effects approaches is included, as well as a discussion of Bayesian methods and cumulative meta-analysis.\u003c\/li\u003e \u003cli\u003eFully documented programs using standard statistical procedures in SAS are available on the Web.\u003c\/li\u003e \u003c\/ul\u003e \u003cp\u003eIdeally suited for practising statisticians and statistically-minded medical professionals, the book will also be of use to graduate students of medical statistics. The book is a self-contained and comprehensive account of the subject and an essential purchase for anyone involved in clinical trials.\u003c\/p\u003e  Introduction\u003cbr\u003e \u003cbr\u003e Protocol development\u003cbr\u003e \u003cbr\u003e Estimating the treatment difference in an individual trial\u003cbr\u003e \u003cbr\u003e Combining estimates of a treatment difference across trials\u003cbr\u003e \u003cbr\u003e Meta-analysis using individual patient data\u003cbr\u003e \u003cbr\u003e Dealing with heterogeneity\u003cbr\u003e \u003cbr\u003e Presentation and interpretation of results\u003cbr\u003e \u003cbr\u003e Selection bias\u003cbr\u003e \u003cbr\u003e Dealing with non-standard datasets\u003cbr\u003e \u003cbr\u003e Inclusion of trials with different study designs\u003cbr\u003e \u003cbr\u003e A Bayesian approach to meta-analysis\u003cbr\u003e \u003cbr\u003e Sequential methods for meta-analysis\u003cbr\u003e \u003cbr\u003e Appendix Methods of estimation and hypothesis testing  \"…highly recommended as essential reading for medical statisticians…\" (Short Book Reviews, April 2003)  \u003cp\u003e\"...comprehensive and well illustrated contribution to the subject...useful for graduate students of medical statistics...\" (Statistics in Medicine, Vol 23(3), 15 February 2004)\u003c\/p\u003e \u003cp\u003e\u003cb\u003eAnne Whitehead\u003c\/b\u003e is Senior Lecturer in Modern and Contemporary Literature at Newcastle University, UK. She is the author of many books.\u003c\/p\u003e \u003cp\u003eOver the last twenty years there has been a dramatic upsurge in the application of meta-analysis to medical research. This has mainly been due to greater emphasis on evidence-based medicine and the need for reliable summaries of the vast and expanding volume of clinical research. At the same time there have been great strides in the development and refinement of the associated statistical methodology. This book describes the planning, conduct and reporting of a meta-analysis as applied to a series of randomized controlled clinical trials.\u003c\/p\u003e \u003cul\u003e \u003cli\u003eThe various approaches are presented within a general unified framework.\u003c\/li\u003e \u003cli\u003eMeta-analysis techniques are described in detail, from their theoretical development through to practical implementation.\u003c\/li\u003e \u003cli\u003eEach topic discussed is supported by detailed worked examples.\u003c\/li\u003e \u003cli\u003eA comparison of fixed and random effects approaches is included, as well as a discussion of Bayesian methods and cumulative meta-analysis.\u003c\/li\u003e \u003cli\u003eFully documented programs using standard statistical procedures in SAS are available on the Web.\u003c\/li\u003e \u003c\/ul\u003e \u003cp\u003eIdeally suited for practising statisticians and statistically-minded medical professionals, the book will also be of use to graduate students of medical statistics. The book is a self-contained and comprehensive account of the subject and an essential purchase for anyone involved in clinical trials.\u003c\/p\u003e","brand":"Wiley","offers":[{"title":"Default Title","offer_id":47989609922789,"sku":"NP9780471983705","price":181.95,"currency_code":"USD","in_stock":false}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/1842\/7735\/files\/9780471983705.jpg?v=1761784798","url":"https:\/\/k12savings.com\/es\/products\/meta-analysis-of-controlled-clinical-trials-isbn-9780471983705","provider":"K12savings","version":"1.0","type":"link"}