{"product_id":"laboratory-animal-endocrinology-isbn-9780471972624","title":"Laboratory Animal Endocrinology","description":"The complex and fascinating subject of endocrinology can often seem rather daunting for non-specialists. For practising endocrinologists too, maintaining a broad overview of the subject can be a major task. Laboratory Animal Endocrinology has been written with both these audiences in mind. Focusing on the species regularly used in experimental studies (including rodents, dogs and monkeys), each chapter presents a wealth of information on hormone structure, synthesis, secretion, receptors, second messengers and their actions, and considers the various physiological and pharmacological processes which may be involved in hormonal regulation. Interspecies' differences in hormonal structure, metabolism and interactions with drugs and other chemicals are particularly important to toxicologists and in drug safety evaluation. Laboratory Animal Endocrinology also explores these areas of research and provides much-needed support for the interpolation of endocrine data from one test species to another and to humans. The book is not intended exclusively for toxicologists however, but will prove indispensable for all those working with laboratory animals.Eine für den Laboralltag unverzichtbare Informationsquelle zu allen Tierarten - Hunden, Nagetieren und Affen -, die in der experimentellen Toxikologie eingesetzt werden. Jedes Kapitel enthält Angaben zur Hormonstruktur, Synthese, Sekretion und Rezeptoren; ein spezieller Abschnitt beschäftigt sich mit Wirkstoffeffekten und toxikologischen Aspekten. Auch für Nicht-Endokrinologen, die mit Labortieren arbeiten! Organisation of Endocrine Systems.\u003cbr\u003e \u003cbr\u003e Endocrine Evolution.\u003cbr\u003e \u003cbr\u003e The Hypothalamus.\u003cbr\u003e \u003cbr\u003e The Pituitary.\u003cbr\u003e \u003cbr\u003e Thyroid and Parathyroid Hormones.\u003cbr\u003e \u003cbr\u003e The Adrenal Glands.\u003cbr\u003e \u003cbr\u003e Atrial Natriuretic Factor.\u003cbr\u003e \u003cbr\u003e The Endocrine Pancreas.\u003cbr\u003e \u003cbr\u003e Gastrointestinal Hormones.\u003cbr\u003e \u003cbr\u003e Reproductive Hormones.\u003cbr\u003e \u003cbr\u003e Endothelin.\u003cbr\u003e \u003cbr\u003e Erythropoietin.\u003cbr\u003e \u003cbr\u003e Index.  Aus dem Inhalt:\u003cbr\u003e Organisation of Endocrine Systems;\u003cbr\u003e Evolution of Interspecies Variation;\u003cbr\u003e The Hypothalamus: Corticotropin Releasing Factor;\u003cbr\u003e Growth Hormone Releasing Hormone;\u003cbr\u003e Somatostatin;\u003cbr\u003e Gonadotrophin Releasing Hormone;\u003cbr\u003e Thyrotropin Releasing Hormone;\u003cbr\u003e The Pituitary: The Anterior Pituitary: Proopiomelanocortin Related peptides;\u003cbr\u003e Luteinizing Hormone and Follicle Stimulating Hormone;\u003cbr\u003e Prolactin;\u003cbr\u003e Growth Hormone;\u003cbr\u003e Thyroid Stimulating Hormone;\u003cbr\u003e The Posterior Pituitary: Arginine Vasopressin;\u003cbr\u003e Oxytocin;\u003cbr\u003e The Thyroid and Parathyroid: Thyroxine, Triiodothyronine and Reverse Triiodothyronine;\u003cbr\u003e Calcitonin, Calcitonin Gene Related Peptide;\u003cbr\u003e Parathyroid Hormone;\u003cbr\u003e The Adrenal: The Adrenal Cortex: Mineralocorticoids;\u003cbr\u003e Glucocorticoids;\u003cbr\u003e Adrenal Androgens;\u003cbr\u003e The Adrenal Medulla: Adrenaline;\u003cbr\u003e Noradrenaline;\u003cbr\u003e Natriuretic Peptides;\u003cbr\u003e The Endocrine Pancreas: Insulin;\u003cbr\u003e Glucagon;\u003cbr\u003e Islet Amyloid Peptide;\u003cbr\u003e Pancreastatin;\u003cbr\u003e Pancreatic Polypeptide;\u003cbr\u003e Gastrointestinal Hormones: Gastrin;\u003cbr\u003e Cholecystokinin;\u003cbr\u003e Somatostatin;\u003cbr\u003e Vasoactive Intestinal Peptide;\u003cbr\u003e Secretin;\u003cbr\u003e Motilin;\u003cbr\u003e Gastrin Releasing Peptide;\u003cbr\u003e Substance P and the Neurokinins;\u003cbr\u003e Peptide YY and Neuropeptide Y;\u003cbr\u003e Gastric Inhibitory Peptide;\u003cbr\u003e Intestinal Glucagon;\u003cbr\u003e Neurotensin;\u003cbr\u003e Galanin;\u003cbr\u003e Gonadal and Reproductive Hormones: Testosterone;\u003cbr\u003e Oestrogens and Progesterone;\u003cbr\u003e Inhibin, Activin and Follistatin;\u003cbr\u003e Relaxin;\u003cbr\u003e Placental Lactogens;\u003cbr\u003e Endothelin;\u003cbr\u003e Erythropoeitin. About the Author Now a freelance toxicology consultant, David Woodman began his research career investigating the endocrine and physiological sequalae of stress in socially deviant populations. This initial interest in endocrinology and hormones led to many years in the pharmaceutical industry, where the author gained practical experience and expert knowledge in toxicology and drug safety with SmithKline Beecham. The complex and fascinating subject of endocrinology can often seem rather daunting for non-specialists. For practising endocrinologists too, maintaining a broad overview of the subject can be a major task. Laboratory Animal Endocrinology has been written with both these audiences in mind. Focusing on the species regularly used in experimental studies (including rodents, dogs and monkeys), each chapter presents a wealth of information on hormone structure, synthesis, secretion, receptors, second messengers and their actions, and considers the various physiological and pharmacological processes which may be involved in hormonal regulation. Interspecies' differences in hormonal structure, metabolism and interactions with drugs and other chemicals are particularly important to toxicologists and in drug safety evaluation. Laboratory Animal Endocrinology also explores these areas of research and provides much-needed support for the interpolation of endocrine data from one test species to another and to humans. The book is not intended exclusively for toxicologists however, but will prove indispensable for all those working with laboratory animals.","brand":"Wiley","offers":[{"title":"Default Title","offer_id":47989504508133,"sku":"NP9780471972624","price":537.95,"currency_code":"USD","in_stock":false}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/1842\/7735\/files\/9780471972624.jpg?v=1761784371","url":"https:\/\/k12savings.com\/es\/products\/laboratory-animal-endocrinology-isbn-9780471972624","provider":"K12savings","version":"1.0","type":"link"}