{"product_id":"karps-cell-and-molecular-biology-isbn-9781119598244","title":"Karp's Cell and Molecular Biology","description":"\u003cp\u003e\u003cb\u003eKarp’s Cell and Molecular Biology\u003c\/b\u003e delivers a concise and illustrative narrative that helps students connect key concepts and experimentation, so they better understand how we know what we know in the world of cell biology.\u003c\/p\u003e \u003cp\u003eThis classic text explores core concepts in considerable depth, often adding experimental detail. It is written in an inviting style and at mid-length, to assist students in managing the plethora of details encountered in the Cell Biology course.\u003c\/p\u003e \u003cp\u003eThe 9th Edition includes two new sections and associated assessment in each chapter that show the relevance of key cell biology concepts to plant cell biology and bioengineering.\u003c\/p\u003e \u003cp\u003e\u003cb\u003e1 \u003c\/b\u003e\u003cb\u003eIntroduction to the Study of Cell and Molecular Biology 1\u003c\/b\u003e\u003c\/p\u003e \u003cp\u003e1.1 The Discovery of Cells 2\u003c\/p\u003e \u003cp\u003e1.2 Basic Properties of Cells 3\u003c\/p\u003e \u003cp\u003e1.3 Two Fundamentally Different Classes of Cells 8\u003c\/p\u003e \u003cp\u003e1.4 Viruses and Viroids 26\u003c\/p\u003e \u003cp\u003e1.5 Green Cells: \u003ci\u003eVolvox\u003c\/i\u003e, an Experiment in Multicellularity 35\u003c\/p\u003e \u003cp\u003e1.6 Engineering Linkage: Tissue Engineering 36\u003c\/p\u003e \u003cp\u003e\u003cb\u003e2 \u003c\/b\u003e\u003cb\u003eThe Chemical Basis of Life 39\u003c\/b\u003e\u003c\/p\u003e \u003cp\u003e2.1 Covalent Bonds 40\u003c\/p\u003e \u003cp\u003e2.2 Engineering Linkage: Radionuclides for Imaging and Treatment 43\u003c\/p\u003e \u003cp\u003e2.3 Noncovalent Bonds 44\u003c\/p\u003e \u003cp\u003e2.4 Acids, Bases, and Buffers 48\u003c\/p\u003e \u003cp\u003e2.5 The Nature of Biological Molecules 49\u003c\/p\u003e \u003cp\u003e2.6 Green Cells: Chemical Fertilizers 52\u003c\/p\u003e \u003cp\u003e2.7 Four Types of Biological Molecules 53\u003c\/p\u003e \u003cp\u003e2.8 The Formation of Complex Macromolecular Structures 95\u003c\/p\u003e \u003cp\u003e\u003cb\u003e3 \u003c\/b\u003e\u003cb\u003eBioenergetics, Enzymes, and Metabolism 99\u003c\/b\u003e\u003c\/p\u003e \u003cp\u003e3.1 Bioenergetics 100\u003c\/p\u003e \u003cp\u003e3.2 Enzymes as Biological Catalysts 108\u003c\/p\u003e \u003cp\u003e3.3 Metabolism 123\u003c\/p\u003e \u003cp\u003e3.4 Green Cells: Regulation of Metabolism by the Light\/Dark Cycle 134\u003c\/p\u003e \u003cp\u003e3.5 Engineering Linkage: Using Metabolism to Image Tumors 135\u003c\/p\u003e \u003cp\u003e\u003cb\u003e4 \u003c\/b\u003e\u003cb\u003eThe Structure and Function of the Plasma Membrane 137\u003c\/b\u003e\u003c\/p\u003e \u003cp\u003e4.1 Introduction to the Plasma Membrane 138\u003c\/p\u003e \u003cp\u003e4.2 The Chemical Composition of Membranes 142\u003c\/p\u003e \u003cp\u003e4.3 Membrane Proteins 148\u003c\/p\u003e \u003cp\u003e4.4 Membrane Lipids and Membrane Fluidity 156\u003c\/p\u003e \u003cp\u003e4.5 The Dynamic Nature of the Plasma Membrane 159\u003c\/p\u003e \u003cp\u003e4.6 The Movement of Substances across Cell Membranes 166\u003c\/p\u003e \u003cp\u003e4.7 Membrane Potentials and Nerve Impulses 189\u003c\/p\u003e \u003cp\u003e4.8 Green Cells: Electrical Signaling in Plants 198\u003c\/p\u003e \u003cp\u003e4.9 Engineering Linkage: Neurotechnology 199\u003c\/p\u003e \u003cp\u003e\u003cb\u003e5 \u003c\/b\u003e\u003cb\u003eAerobic Respiration and the Mitochondrion 203\u003c\/b\u003e\u003c\/p\u003e \u003cp\u003e5.1 Mitochondrial Structure and Function 204\u003c\/p\u003e \u003cp\u003e5.2 Aerobic Metabolism in the Mitochondrion 209\u003c\/p\u003e \u003cp\u003e5.3 The Role of Mitochondria in the Formation of ATP 215\u003c\/p\u003e \u003cp\u003e5.4 Engineering Linkage: Measuring Blood Oxygen 224\u003c\/p\u003e \u003cp\u003e5.5 Establishment of a Proton-Motive Force 225\u003c\/p\u003e \u003cp\u003e5.6 The Machinery for ATP Formation 226\u003c\/p\u003e \u003cp\u003e5.7 Peroxisomes 233\u003c\/p\u003e \u003cp\u003e5.8 Green Cells: Glyoxysomes 237\u003c\/p\u003e \u003cp\u003e\u003cb\u003e6 \u003c\/b\u003e\u003cb\u003ePhotosynthesis and the Chloroplast 239\u003c\/b\u003e\u003c\/p\u003e \u003cp\u003e6.1 The Origin of Photosynthesis 240\u003c\/p\u003e \u003cp\u003e6.2 Chloroplast Structure 241\u003c\/p\u003e \u003cp\u003e6.3 An Overview of Photosynthetic Metabolism 243\u003c\/p\u003e \u003cp\u003e6.4 The Absorption of Light 244\u003c\/p\u003e \u003cp\u003e6.5 Green Cells: Chromoplasts 246\u003c\/p\u003e \u003cp\u003e6.6 Photosynthetic Units and Reaction Centers 247\u003c\/p\u003e \u003cp\u003e6.7 Photophosphorylation 255\u003c\/p\u003e \u003cp\u003e6.8 Carbon Dioxide Fixation and the Synthesis of Carbohydrate 256\u003c\/p\u003e \u003cp\u003e6.9 Engineering Linkage: Photodynamic Therapy 264\u003c\/p\u003e \u003cp\u003e\u003cb\u003e7 \u003c\/b\u003e\u003cb\u003eInteractions Between Cells and Their Environment 267\u003c\/b\u003e\u003c\/p\u003e \u003cp\u003e7.1 Extracellular Interactions 268\u003c\/p\u003e \u003cp\u003e7.2 Engineering Linkage: Organoids 277\u003c\/p\u003e \u003cp\u003e7.3 Interactions of Cells with Extracellular Materials 278\u003c\/p\u003e \u003cp\u003e7.4 Interactions of Cells with Other Cells 284\u003c\/p\u003e \u003cp\u003e7.5 Tight Junctions: Sealing the Extracellular Space 294\u003c\/p\u003e \u003cp\u003e7.6 Intercellular Communication 296\u003c\/p\u003e \u003cp\u003e7.7 Cell Walls 303\u003c\/p\u003e \u003cp\u003e7.8 Green Cells: Cell Walls and Plant Terrestrialization 306\u003c\/p\u003e \u003cp\u003e\u003cb\u003e8 \u003c\/b\u003e\u003cb\u003eCytoplasmic Membrane Systems: Structure, Function, and Membrane Trafficking 307\u003c\/b\u003e\u003c\/p\u003e \u003cp\u003e8.1 An Overview of the Endomembrane System 308\u003c\/p\u003e \u003cp\u003e8.2 A Few Approaches to the Study of Endomembranes 311\u003c\/p\u003e \u003cp\u003e8.3 The Endoplasmic Reticulum 317\u003c\/p\u003e \u003cp\u003e8.4 The Golgi Complex 330\u003c\/p\u003e \u003cp\u003e8.5 Types of Vesicle Transport 335\u003c\/p\u003e \u003cp\u003e8.6 Engineering Linkage: Extracellular Vesicles for Drug Delivery 347\u003c\/p\u003e \u003cp\u003e8.7 Lysosomes 348\u003c\/p\u003e \u003cp\u003e8.8 Green Cells: Plant Cell Vacuoles 350\u003c\/p\u003e \u003cp\u003e8.9 The Endocytic Pathway: Moving Membrane and Materials into the Cell Interior 351\u003c\/p\u003e \u003cp\u003e8.10 Posttranslational Uptake of Proteins by Peroxisomes, Mitochondria, and Chloroplasts 363\u003c\/p\u003e \u003cp\u003e\u003cb\u003e9 \u003c\/b\u003e\u003cb\u003eThe Cytoskeleton and Cell Motility 369\u003c\/b\u003e\u003c\/p\u003e \u003cp\u003e9.1 Overview of the Major Functions of the Cytoskeleton 370\u003c\/p\u003e \u003cp\u003e9.2 Structure and Function of Microtubules 372\u003c\/p\u003e \u003cp\u003e9.3 Green Cells: Why the Woodbine Twineth 376\u003c\/p\u003e \u003cp\u003e9.4 Motor Proteins: Kinesins and Dyneins 377\u003c\/p\u003e \u003cp\u003e9.5 Microtubule-Organizing Centers (MTOCs) 383\u003c\/p\u003e \u003cp\u003e9.6 Structure and Function of Cilia and Flagella 390\u003c\/p\u003e \u003cp\u003e9.7 Intermediate Filaments 398\u003c\/p\u003e \u003cp\u003e9.8 Actin and Myosin 402\u003c\/p\u003e \u003cp\u003e9.9 Muscle Organization and Contraction 410\u003c\/p\u003e \u003cp\u003e9.10 Engineering Linkage: Muscle Biomechanics 416\u003c\/p\u003e \u003cp\u003e9.11 Actin-Binding Proteins 417\u003c\/p\u003e \u003cp\u003e9.12 Cellular Motility 420\u003c\/p\u003e \u003cp\u003e9.13 The Bacterial Cytoskeleton 430\u003c\/p\u003e \u003cp\u003e\u003cb\u003e10 \u003c\/b\u003e\u003cb\u003eThe Nature of the Gene and the Genome 433\u003c\/b\u003e\u003c\/p\u003e \u003cp\u003e10.1 The Concept of a Gene as a Unit of Inheritance 434\u003c\/p\u003e \u003cp\u003e10.2 The Discovery of Chromosomes 435\u003c\/p\u003e \u003cp\u003e10.3 Chromosomes as the Carriers of Genetic Information 436\u003c\/p\u003e \u003cp\u003e10.4 The Chemical Nature of the Gene 441\u003c\/p\u003e \u003cp\u003e10.5 The Complexity of the Genome 452\u003c\/p\u003e \u003cp\u003e10.6 The Stability of the Genome 458\u003c\/p\u003e \u003cp\u003e10.7 Sequencing Genomes: The Footprints of Biological Evolution 464\u003c\/p\u003e \u003cp\u003e10.8 Engineering Linkage: Engineering Genomes 467\u003c\/p\u003e \u003cp\u003e10.9 The Genetic Basis of “Being Human” 468\u003c\/p\u003e \u003cp\u003e10.10 Green Cells: Gene Transfer by \u003ci\u003eAgrobacterium tumefaciens \u003c\/i\u003e475\u003c\/p\u003e \u003cp\u003e\u003cb\u003e11 \u003c\/b\u003e\u003cb\u003eThe Central Dogma: DNA to RNA to Protein 477\u003c\/b\u003e\u003c\/p\u003e \u003cp\u003e11.1 The Relationships among Genes, Proteins, and RNAs 478\u003c\/p\u003e \u003cp\u003e11.2 An Overview of Transcription in Both Prokaryotic and Eukaryotic Cells 483\u003c\/p\u003e \u003cp\u003e11.3 Synthesis and Processing of Eukaryotic Ribosomal and Transfer RNAs 487\u003c\/p\u003e \u003cp\u003e11.4 Synthesis and Structure of Eukaryotic Messenger RNAs 491\u003c\/p\u003e \u003cp\u003e11.5 Small Regulatory RNAs and RNA Silencing Pathways 507\u003c\/p\u003e \u003cp\u003e11.6 Green Cells: Long-Range siRNA Movement 512\u003c\/p\u003e \u003cp\u003e11.7 CRISPR and Other Noncoding RNAs 513\u003c\/p\u003e \u003cp\u003e11.8 Encoding Genetic Information 514\u003c\/p\u003e \u003cp\u003e11.9 Decoding the Codons: The Role of Transfer RNAs 517\u003c\/p\u003e \u003cp\u003e11.10 Translating Genetic Information 520\u003c\/p\u003e \u003cp\u003e11.11 Engineering Linkage: DNA Origami 534\u003c\/p\u003e \u003cp\u003e\u003cb\u003e12 \u003c\/b\u003e\u003cb\u003eControl of Gene Expression 537\u003c\/b\u003e\u003c\/p\u003e \u003cp\u003e12.1 Control of Gene Expression in Bacteria 538\u003c\/p\u003e \u003cp\u003e12.2 Engineering Linkage: Building Digital Logic with Genes 542\u003c\/p\u003e \u003cp\u003e12.3 Structure of the Nuclear Envelope 543\u003c\/p\u003e \u003cp\u003e12.4 Chromosomes and Chromatin 550\u003c\/p\u003e \u003cp\u003e12.5 The Nucleus as an Organized Organelle 567\u003c\/p\u003e \u003cp\u003e12.6 An Overview of Gene Regulation in Eukaryotes 570\u003c\/p\u003e \u003cp\u003e12.7 Transcriptional Control 571\u003c\/p\u003e \u003cp\u003e12.8 Green Cells: The ABC Model and MADS Domain Transcription Factors 592\u003c\/p\u003e \u003cp\u003e12.9 RNA Processing Control 593\u003c\/p\u003e \u003cp\u003e12.10 Translational Control 594\u003c\/p\u003e \u003cp\u003e12.11 Posttranslational Control: Determining Protein Stability 601\u003c\/p\u003e \u003cp\u003e\u003cb\u003e13 \u003c\/b\u003e\u003cb\u003eDNA Replication and Repair 605\u003c\/b\u003e\u003c\/p\u003e \u003cp\u003e13.1 DNA Replication 606\u003c\/p\u003e \u003cp\u003e13.2 DNA Replication in Bacterial Cells 610\u003c\/p\u003e \u003cp\u003e13.3 The Structure and Functions of DNA Polymerases 617\u003c\/p\u003e \u003cp\u003e13.4 Replication in Viruses 621\u003c\/p\u003e \u003cp\u003e13.5 Engineering Linkage: Storing Data in DNA 621\u003c\/p\u003e \u003cp\u003e13.6 DNA Replication in Eukaryotic Cells 622\u003c\/p\u003e \u003cp\u003e13.7 DNA Repair 628\u003c\/p\u003e \u003cp\u003e13.8 Green Cells: Gamma Gardens 632\u003c\/p\u003e \u003cp\u003e13.9 Between Replication and Repair 633\u003c\/p\u003e \u003cp\u003e\u003cb\u003e14 \u003c\/b\u003e\u003cb\u003eCell Division 637\u003c\/b\u003e\u003c\/p\u003e \u003cp\u003e14.1 The Cell Cycle 638\u003c\/p\u003e \u003cp\u003e14.2 M Phase: Mitosis and Cytokinesis 651\u003c\/p\u003e \u003cp\u003e14.3 Engineering Linkage: The Role of Membrane Tension in Cell Division 672\u003c\/p\u003e \u003cp\u003e14.4 Green Cells: Unique Aspects of Plant Cell Division 673\u003c\/p\u003e \u003cp\u003e14.5 Meiosis 673\u003c\/p\u003e \u003cp\u003e\u003cb\u003e15 \u003c\/b\u003e\u003cb\u003eCell Signaling and Signal Transduction: Communication between Cells 685\u003c\/b\u003e\u003c\/p\u003e \u003cp\u003e15.1 The Basic Elements of Cell Signaling Systems 686\u003c\/p\u003e \u003cp\u003e15.2 A Survey of Extracellular Messengers and Their Receptors 689\u003c\/p\u003e \u003cp\u003e15.3 G Protein-Coupled Receptors and Their Second Messengers 690\u003c\/p\u003e \u003cp\u003e15.4 Engineering Linkage: Biosensors in Medicine and Biology 709\u003c\/p\u003e \u003cp\u003e15.5 Protein-Tyrosine Phosphorylation as a Mechanism for Signal Transduction 710\u003c\/p\u003e \u003cp\u003e15.6 Green Cells: Auxin Signaling 721\u003c\/p\u003e \u003cp\u003e15.7 The Role of Calcium as an Intracellular Messenger 721\u003c\/p\u003e \u003cp\u003e15.8 Convergence, Divergence, and Cross-Talk among Different Signaling Pathways 726\u003c\/p\u003e \u003cp\u003e15.9 The Role of NO as an Intracellular Messenger 729\u003c\/p\u003e \u003cp\u003e15.10 Apoptosis (Programmed Cell Death) 731\u003c\/p\u003e \u003cp\u003e\u003cb\u003e16 \u003c\/b\u003e\u003cb\u003eCancer 737\u003c\/b\u003e\u003c\/p\u003e \u003cp\u003e16.1 Basic Properties of a Cancer Cell 738\u003c\/p\u003e \u003cp\u003e16.2 The Causes of Cancer 741\u003c\/p\u003e \u003cp\u003e16.3 Cancer: A Genetic Disorder 747\u003c\/p\u003e \u003cp\u003e16.4 Engineering Linkage: Therapeutic Radiation 767\u003c\/p\u003e \u003cp\u003e16.5 Green Cells: Plant-Based Chemotherapies 767\u003c\/p\u003e \u003cp\u003e16.6 Strategies for Combating Cancer 768\u003c\/p\u003e \u003cp\u003e\u003cb\u003e17 \u003c\/b\u003e\u003cb\u003eThe Immune Response 775\u003c\/b\u003e\u003c\/p\u003e \u003cp\u003e17.1 An Overview of the Immune Response 776\u003c\/p\u003e \u003cp\u003e17.2 Green Cells: The Plant Immune System 780\u003c\/p\u003e \u003cp\u003e17.3 The Clonal Selection Theory as It Applies to B Cells 781\u003c\/p\u003e \u003cp\u003e17.4 T Lymphocytes: Activation and Mechanism of Action 787\u003c\/p\u003e \u003cp\u003e17.5 Selected Topics on the Cellular and Molecular Basis of Immunity 790\u003c\/p\u003e \u003cp\u003e17.6 Engineering Linkage: Adoptive T-cell Therapy 808\u003c\/p\u003e \u003cp\u003e17.7 Signal Transduction Pathways in Lymphocyte Activation 809\u003c\/p\u003e \u003cp\u003e\u003cb\u003e18 \u003c\/b\u003e\u003cb\u003eTechniques in Cell and Molecular Biology 811\u003c\/b\u003e\u003c\/p\u003e \u003cp\u003e18.1 The Light Microscope 812\u003c\/p\u003e \u003cp\u003e18.2 Transmission Electron Microscopy 822\u003c\/p\u003e \u003cp\u003e18.3 Scanning Electron and Atomic Force Microscopy 828\u003c\/p\u003e \u003cp\u003e18.4 The Use of Radioisotopes 830\u003c\/p\u003e \u003cp\u003e18.5 Cell Culture 831\u003c\/p\u003e \u003cp\u003e18.6 The Fractionation of a Cell’s Contents by Differential Centrifugation 833\u003c\/p\u003e \u003cp\u003e18.7 Isolation, Purification, and Fractionation of Proteins 834\u003c\/p\u003e \u003cp\u003e18.8 Determining the Structure of Proteins and Multisubunit Complexes 840\u003c\/p\u003e \u003cp\u003e18.9 Fractionation of Nucleic Acids 842\u003c\/p\u003e \u003cp\u003e18.10 Nucleic Acid Hybridization 845\u003c\/p\u003e \u003cp\u003e18.11 Chemical Synthesis of DNA 846\u003c\/p\u003e \u003cp\u003e18.12 Recombinant DNA Technology 847\u003c\/p\u003e \u003cp\u003e18.13 Enzymatic Amplification of DNA by PCR 851\u003c\/p\u003e \u003cp\u003e18.14 DNA Sequencing 853\u003c\/p\u003e \u003cp\u003e18.15 DNA Libraries 855\u003c\/p\u003e \u003cp\u003e18.16 DNA Transfer into Eukaryotic Cells and Mammalian Embryos 857\u003c\/p\u003e \u003cp\u003e18.17 Gene Editing and Silencing 860\u003c\/p\u003e \u003cp\u003e18.18 The Use of Antibodies 864\u003c\/p\u003e \u003cp\u003eAdditional Readings A-1\u003c\/p\u003e \u003cp\u003eGlossary G-1\u003c\/p\u003e \u003cp\u003eIndex I-1\u003c\/p\u003e","brand":"Wiley","offers":[{"title":"Default Title","offer_id":47989495857381,"sku":"NP9781119598244","price":111.0,"currency_code":"USD","in_stock":false}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/1842\/7735\/files\/9781119598244.jpg?v=1761784335","url":"https:\/\/k12savings.com\/es\/products\/karps-cell-and-molecular-biology-isbn-9781119598244","provider":"K12savings","version":"1.0","type":"link"}