{"product_id":"integrative-organismal-biology-isbn-9781118398784","title":"Integrative Organismal Biology","description":"\u003cp\u003e\u003ci\u003eIntegrative Organismal Biology\u003c\/i\u003e synthesizes current understandings of the causes and consequences of individual variation at the physiological, behavioral and organismal levels. Emphasizing key topics such as phenotypic plasticity and flexibility, and summarizing emerging areas such as ecological immunology, oxidative stress biology and others, \u003ci\u003eIntegrative Organismal Biology\u003c\/i\u003e pulls together information from diverse disciplines to provide a synthetic view of the role of the individual in evolution. \u003cbr\u003e \u003cbr\u003e Beginning with the role of the individual in evolutionary and ecological processes, the book covers theory and mechanism from both classic and modern perspectives. Chapters explore concepts such as phenotypic plasticity, genetic and epigenetic variation, physiological and phenotypic variation, homeostasis, and gene and physiological regulatory networks. A concluding section interweaves these concepts through a series of case studies of life processes such as aging, reproduction, and immune defense.\u003c\/p\u003e Written and edited by leaders in the field, \u003ci\u003eIntegrative Organismal Biology\u003c\/i\u003e will be an important advanced textbook for students and researchers across a variety of subdisciplines of integrative biology. \u003cp\u003eAcknowledgments xiii\u003c\/p\u003e \u003cp\u003eNotes on Contributors xv\u003c\/p\u003e \u003cp\u003e\u003cb\u003e1 Plasticity, Complexity, and the Individual 1\u003cbr\u003e \u003c\/b\u003e\u003ci\u003eCameron K. Ghalambor, Lynn B. Martin, and H. Arthur Woods\u003c\/i\u003e\u003c\/p\u003e \u003cp\u003eIntroduction 1\u003c\/p\u003e \u003cp\u003eBridging the Conceptual Divide 3\u003c\/p\u003e \u003cp\u003eIntegrative Organismal Biology: Progress to Date 4\u003c\/p\u003e \u003cp\u003ePhenotypic Plasticity: The Link between Individuals, Environments, and Evolution 6\u003c\/p\u003e \u003cp\u003eThe Problem of Complexity 9\u003c\/p\u003e \u003cp\u003eEmbracing the Individual and the Union of Functional and Evolutionary Biology 11\u003c\/p\u003e \u003cp\u003eConclusion 14\u003c\/p\u003e \u003cp\u003eReferences 15\u003c\/p\u003e \u003cp\u003e\u003cb\u003e2 The Ecological and Evolutionary Importance of Variation in Life History Reaction Norms 23\u003cbr\u003e \u003c\/b\u003e\u003ci\u003eDaniel H. Nussey\u003c\/i\u003e\u003c\/p\u003e \u003cp\u003eIntroduction 23\u003c\/p\u003e \u003cp\u003eThe Reaction Norm Approach and Individual by Environment Interactions (I × E) 25\u003c\/p\u003e \u003cp\u003eWhy Do Reaction Norms Vary? 27\u003c\/p\u003e \u003cp\u003eCauses and Consequences of Variation in Avian Phenological Plasticity 29\u003c\/p\u003e \u003cp\u003eIntegrating Field and Laboratory Studies of Life History Plasticity 32\u003c\/p\u003e \u003cp\u003eThe Challenges Ahead 34\u003c\/p\u003e \u003cp\u003eReferences 35\u003c\/p\u003e \u003cp\u003e\u003cb\u003e3 Curve-thinking: Understanding Reaction Norms and Developmental Trajectories as Traits 39\u003cbr\u003e \u003c\/b\u003e\u003ci\u003eJoel Kingsolver, Sarah Diamond, and Richard Gomulkiewicz\u003c\/i\u003e\u003c\/p\u003e \u003cp\u003eIntroduction 39\u003c\/p\u003e \u003cp\u003eCharacterizing Curves 41\u003c\/p\u003e \u003cp\u003eVariation among Curves 42\u003c\/p\u003e \u003cp\u003eSimplicity and Biological Hypotheses 48\u003c\/p\u003e \u003cp\u003eSummary and Future Directions 51\u003c\/p\u003e \u003cp\u003eAcknowledgments 52\u003c\/p\u003e \u003cp\u003eReferences 52\u003c\/p\u003e \u003cp\u003e\u003cb\u003e4 Plasticity and Personality 55\u003cbr\u003e \u003c\/b\u003e\u003ci\u003eKimberley J. Mathot and Niels J. Dingemanse\u003c\/i\u003e\u003c\/p\u003e \u003cp\u003eAnimal Personality: Moving beyond Optimality and Embracing Individual Differences 55\u003c\/p\u003e \u003cp\u003eIndividual Differences in Behavioral Plasticity 58\u003c\/p\u003e \u003cp\u003ePersonality-Related Differences in Plasticity 60\u003c\/p\u003e \u003cp\u003eAdaptive Explanations for Personality-Related Differences in Plasticity 61\u003c\/p\u003e \u003cp\u003eEcological and Evolutionary Implications of Personality and Plasticity 63\u003c\/p\u003e \u003cp\u003eGenetic and Environmental Underpinnings 64\u003c\/p\u003e \u003cp\u003eDesigns to Study Personality-Related Differences in Plasticity 65\u003c\/p\u003e \u003cp\u003eConclusions and Future Directions 66\u003c\/p\u003e \u003cp\u003eReferences 66\u003c\/p\u003e \u003cp\u003e\u003cb\u003e5 Induction and Function of Polyphenic Morphs: Proximate Regulatory Mechanisms and Evolutionary Implications 71\u003cbr\u003e \u003c\/b\u003e\u003ci\u003eAnthony J. Zera and Jennifer A. Brisson\u003c\/i\u003e\u003c\/p\u003e \u003cp\u003eIntroduction 71\u003c\/p\u003e \u003cp\u003eBackground on Endocrinology and Gene Regulation 74\u003c\/p\u003e \u003cp\u003eCase Studies 77\u003c\/p\u003e \u003cp\u003eSummary and Future Directions 83\u003c\/p\u003e \u003cp\u003eAcknowledgments 85\u003c\/p\u003e \u003cp\u003eReferences 85\u003c\/p\u003e \u003cp\u003e\u003cb\u003e6 Evolutionary Systems Biology: Shifting Focus to the Context-dependency of Genetic Effects 91\u003cbr\u003e \u003c\/b\u003e\u003ci\u003eMihaela Pavličev and Günter P. Wagner\u003c\/i\u003e\u003c\/p\u003e \u003cp\u003eIntroduction 91\u003c\/p\u003e \u003cp\u003eTwo Ends of the Spectrum in Evolutionary Biology 92\u003c\/p\u003e \u003cp\u003eContext-Dependency in Population Genetics: Epistasis 94\u003c\/p\u003e \u003cp\u003eGenetic Effects Structured by Development: Pleiotropy 95\u003c\/p\u003e \u003cp\u003eWhat Are the Consequences of Context-Dependency? 95\u003c\/p\u003e \u003cp\u003eGeneralizing SPC Model: Interaction of Gene Effects, or Effects of Interactions? 100\u003c\/p\u003e \u003cp\u003eConclusion 103\u003c\/p\u003e \u003cp\u003eReferences 104\u003c\/p\u003e \u003cp\u003e\u003cb\u003e7 The Role of Ecological Epigenetics in Integrative Biology 109\u003cbr\u003e \u003c\/b\u003e\u003ci\u003eAaron W. Schrey, Joshua Banta, Holly J. Kilvitis, and Christina L. Richards\u003c\/i\u003e\u003c\/p\u003e \u003cp\u003eIntroduction 109\u003c\/p\u003e \u003cp\u003eEcological Epigenetics 112\u003c\/p\u003e \u003cp\u003eCase Study: \u003ci\u003eArabidopsis Thaliana\u003c\/i\u003e 114\u003c\/p\u003e \u003cp\u003eConclusion 115\u003c\/p\u003e \u003cp\u003eReferences 115\u003c\/p\u003e \u003cp\u003e\u003cb\u003e8 An Elephant in the Fog: Unifying Concepts of Physiological Stasis and Change 119\u003cbr\u003e \u003c\/b\u003e\u003ci\u003eH. Arthur Woods and J. Keaton Wilson\u003c\/i\u003e\u003c\/p\u003e \u003cp\u003eIntroduction 119\u003c\/p\u003e \u003cp\u003eElaborations of Stasis and Change 120\u003c\/p\u003e \u003cp\u003eAxes of (Dis)similarity 124\u003c\/p\u003e \u003cp\u003eConstructing a Conceptual Elephant 126\u003c\/p\u003e \u003cp\u003eUnification Diffuses Concepts and Tools 127\u003c\/p\u003e \u003cp\u003eCosts and Constraints 130\u003c\/p\u003e \u003cp\u003eConclusion 131\u003c\/p\u003e \u003cp\u003eAcknowledgments 132\u003c\/p\u003e \u003cp\u003eReferences 132\u003c\/p\u003e \u003cp\u003e\u003cb\u003e9 Physiological Regulatory Networks: The Orchestra of Life? 137\u003cbr\u003e \u003c\/b\u003e\u003ci\u003eLynn B. Martin and Alan A. Cohen\u003c\/i\u003e\u003c\/p\u003e \u003cp\u003eIntroduction 137\u003c\/p\u003e \u003cp\u003eWhat is a Physiological Regulatory Network (PRN)? 138\u003c\/p\u003e \u003cp\u003eKnown and Expected Characteristics of PRNs 140\u003c\/p\u003e \u003cp\u003eOrganismal Implications of PRNs: Stability and Resiliency 142\u003c\/p\u003e \u003cp\u003eEcological and Evolutionary Implications of PRNs: Constraints and Evolvability 146\u003c\/p\u003e \u003cp\u003eOpen Issues 147\u003c\/p\u003e \u003cp\u003eConclusion 148\u003c\/p\u003e \u003cp\u003eGlossary 148\u003c\/p\u003e \u003cp\u003eReferences 149\u003c\/p\u003e \u003cp\u003e\u003cb\u003e10 Integrating Costs of Reproduction Between the Sexes 153\u003cbr\u003e \u003c\/b\u003e\u003ci\u003eRobert M. Cox\u003c\/i\u003e\u003c\/p\u003e \u003cp\u003eIntroduction 153\u003c\/p\u003e \u003cp\u003eIntegrating Costs of Reproduction through Common Currencies 154\u003c\/p\u003e \u003cp\u003eIntralocus Sexual Conflict and Life-History Evolution 156\u003c\/p\u003e \u003cp\u003eImmunocompetence Handicaps and Sex-Specific Costs 158\u003c\/p\u003e \u003cp\u003eIntegrating Sex-Specific Processes through Shared Regulatory Axes 159\u003c\/p\u003e \u003cp\u003eSummary 163\u003c\/p\u003e \u003cp\u003eAcknowledgments 164\u003c\/p\u003e \u003cp\u003eReferences 164\u003c\/p\u003e \u003cp\u003e\u003cb\u003e11 Immune Systems: Linking Organisms, Populations, and Evolution Through Disease 169\u003cbr\u003e \u003c\/b\u003e\u003ci\u003eJames S. Adelman\u003c\/i\u003e\u003c\/p\u003e \u003cp\u003eIntroduction 169\u003c\/p\u003e \u003cp\u003eImmune Systems: A Brief Overview 170\u003c\/p\u003e \u003cp\u003eProposed Divers of Immune Heterogeneity 172\u003c\/p\u003e \u003cp\u003eConsequences of Immune Heterogeneity: Theoretical Studies 173\u003c\/p\u003e \u003cp\u003eConsequences of Immune Heterogeneity: Empirical Studies 178\u003c\/p\u003e \u003cp\u003eBridging the Divide between Theory and Experiment 180\u003c\/p\u003e \u003cp\u003eAcknowledgments 181\u003c\/p\u003e \u003cp\u003eReferences 181\u003c\/p\u003e \u003cp\u003e\u003cb\u003e12 Developmental Plasticity of Individual Variation in Stress Responses 187\u003cbr\u003e \u003c\/b\u003e\u003ci\u003eHaruka Wada\u003c\/i\u003e\u003c\/p\u003e \u003cp\u003eIntroduction 187\u003c\/p\u003e \u003cp\u003eWhen is a Change in Environment a Stressor? 188\u003c\/p\u003e \u003cp\u003eOrganismal Responses to Stressors 189\u003c\/p\u003e \u003cp\u003eIntegrating Developmental Plasticity 191\u003c\/p\u003e \u003cp\u003eFuture Directions 196\u003c\/p\u003e \u003cp\u003eConclusion 200\u003c\/p\u003e \u003cp\u003eReferences 200\u003c\/p\u003e \u003cp\u003e\u003cb\u003e13 A Common Framework for the Regulation of Growth And Size: Stepping Away From the Trees to See the Forest 207\u003cbr\u003e \u003c\/b\u003e\u003ci\u003eGoggy Davidowitz and Bryan R. Helm\u003c\/i\u003e\u003c\/p\u003e \u003cp\u003eIntroduction 207\u003c\/p\u003e \u003cp\u003eA General Framework for the Regulation of Growth and Body Size 208\u003c\/p\u003e \u003cp\u003eCommonalities in the Regulation of Body Size Across Taxa 209\u003c\/p\u003e \u003cp\u003eUsing the Framework to Address the Ecology and Evolution of Growth and Size 213\u003c\/p\u003e \u003cp\u003eAcknowledgments 214\u003c\/p\u003e \u003cp\u003eReferences 214\u003c\/p\u003e \u003cp\u003e\u003cb\u003e14 Adding Fuel to the “Fire of Life”: Energy Budgets Across Levels of Variation in Ectotherms and Endotherms 219\u003cbr\u003e \u003c\/b\u003e\u003ci\u003eVincent Careau, Shaun S. Killen, and Neil B. Metcalfe\u003c\/i\u003e\u003c\/p\u003e \u003cp\u003eIntroduction 219\u003c\/p\u003e \u003cp\u003eIntrinsic Factors that Explain Variation in MR 221\u003c\/p\u003e \u003cp\u003eExtrinsic Factors that Explain Variation in MR 222\u003c\/p\u003e \u003cp\u003eEnergy Budgets 223\u003c\/p\u003e \u003cp\u003eMetabolic Scopes: A Different Kind of Energetic Budgeting 226\u003c\/p\u003e \u003cp\u003eEnergetic Constraints on Individual Behavior 227\u003c\/p\u003e \u003cp\u003eConclusions and Future Perspectives 229\u003c\/p\u003e \u003cp\u003eReferences 229\u003c\/p\u003e \u003cp\u003e\u003cb\u003e15 Biological Timekeeping: Individual Variation, Performance, and Fitness 235\u003cbr\u003e \u003c\/b\u003e\u003ci\u003eScott A. MacDougall-Shackleton, Heather E. Watts, and Thomas P. Hahn\u003c\/i\u003e\u003c\/p\u003e \u003cp\u003eIntroduction 235\u003c\/p\u003e \u003cp\u003eEndogenous versus Environmental Drivers 235\u003c\/p\u003e \u003cp\u003eResponses to Entrainment by Endogenous Clocks Varies over Their Cycle 236\u003c\/p\u003e \u003cp\u003eGeneral Properties of Biological Rhythms 238\u003c\/p\u003e \u003cp\u003eCircadian Rhythms 238\u003c\/p\u003e \u003cp\u003eCircannual Cycles and Seasonality 244\u003c\/p\u003e \u003cp\u003eConclusion 250\u003c\/p\u003e \u003cp\u003eAcknowledgments 250\u003c\/p\u003e \u003cp\u003eReferences 250\u003c\/p\u003e \u003cp\u003e\u003cb\u003e16 Senescence: Integrating Biology From Cradle To the Grave 257\u003cbr\u003e \u003c\/b\u003e\u003ci\u003eMark F. Haussmann and Lisa A. Treidel\u003c\/i\u003e\u003c\/p\u003e \u003cp\u003eIntroduction 257\u003c\/p\u003e \u003cp\u003eUltimate Theories of Aging 258\u003c\/p\u003e \u003cp\u003eProximate Theories of Aging 259\u003c\/p\u003e \u003cp\u003eFuture Directions 265\u003c\/p\u003e \u003cp\u003eReferences 269\u003c\/p\u003e \u003cp\u003e\u003cb\u003e17 Linking Physiology, Climate, and Species Distributional Ranges 277\u003cbr\u003e \u003c\/b\u003e\u003ci\u003eFrancisco Bozinovic and Daniel E. Naya\u003c\/i\u003e\u003c\/p\u003e \u003cp\u003eIntroduction 277\u003c\/p\u003e \u003cp\u003eLimits to Geographic Ranges: Examples Involving Capacities and Tolerances 278\u003c\/p\u003e \u003cp\u003eLimits to Geographic Ranges: Examples Involving Tolerances and Plasticity 281\u003c\/p\u003e \u003cp\u003eProximate Causes behind Macrophysiological Patterns 283\u003c\/p\u003e \u003cp\u003eConclusions and Future Directions 286\u003c\/p\u003e \u003cp\u003eAcknowledgments 287\u003c\/p\u003e \u003cp\u003eReferences 287\u003c\/p\u003e \u003cp\u003e\u003cb\u003e18 Trade-offs and Biological Diversity: Integrative Answers to Ecological Questions 291\u003cbr\u003e \u003c\/b\u003e\u003ci\u003ePaul R. Martin\u003c\/i\u003e\u003c\/p\u003e \u003cp\u003eIntroduction 291\u003c\/p\u003e \u003cp\u003eEvolutionary Trade-Offs and the Distributions of Species 298\u003c\/p\u003e \u003cp\u003eAre Trade-Offs Universal? 299\u003c\/p\u003e \u003cp\u003eTrade-Offs, Integrative Biology, and Moving Forward 300\u003c\/p\u003e \u003cp\u003eAcknowledgments 303\u003c\/p\u003e \u003cp\u003eReferences 303\u003c\/p\u003e \u003cp\u003e\u003cb\u003e19 Conclusions: The Central Role of the Organism in Biology 309\u003cbr\u003e \u003c\/b\u003e\u003ci\u003eH. Arthur Woods, Lynn B. Martin, and Cameron K. Ghalambor\u003c\/i\u003e\u003c\/p\u003e \u003cp\u003eIntroduction 309\u003c\/p\u003e \u003cp\u003eHow Do Complex Traits Interact with Complex Environments? 311\u003c\/p\u003e \u003cp\u003eWhere Does Organismal Diversity Come From and How Does It Evolve? 312\u003c\/p\u003e \u003cp\u003eHow Useful is Reductionism? 313\u003c\/p\u003e \u003cp\u003eWhat are the Consequences of Emergence for Organismal Biology? 314\u003c\/p\u003e \u003cp\u003eConclusions to the Conclusions 315\u003c\/p\u003e \u003cp\u003eAcknowledgments 315\u003c\/p\u003e \u003cp\u003eReferences 315\u003c\/p\u003e \u003cp\u003eIndex 319\u003c\/p\u003e \u003cp\u003e“The organism was once the major driving focus of research questions, and this book should usher in a new era of technologically advanced organismcentered research.”  (\u003ci\u003eThe Quarterly Review of Biology\u003c\/i\u003e, 1 December 2015)\u003c\/p\u003e \u003cb\u003eLynn B. Martin\u003c\/b\u003e is Assistant Professor in the Department of Integrative Biology at the University of South Florida. Dr. Martin is on the editorial boards for Functional Ecology and Proceedings of the Royal Society of London B, and serves as an ad hoc reviewer for numerous journals including \u003ci\u003eAmerican Naturalist\u003c\/i\u003e, \u003ci\u003eGeneral and Comparative Endocrinology\u003c\/i\u003e, \u003ci\u003eEvolutionary Ecology\u003c\/i\u003e, and \u003ci\u003eScience\u003c\/i\u003e. \u003cp\u003e\u003cb\u003eCameron K. Ghalambor\u003c\/b\u003e is Associate Professor in the Department of Biology at Colorado State University. The author of numerous peer-reviewed publications, Dr. Ghalambor also provides reviews for a number of journals including \u003ci\u003eEvolution\u003c\/i\u003e and \u003ci\u003eNature\u003c\/i\u003e, and has served as a grant reviewer for the National Science Foundation, Murdoch Trust, and Natural Environment Research Council, UK.\u003c\/p\u003e \u003cp\u003e\u003cb\u003eArt Woods\u003c\/b\u003e is Associate Professor in the Division of Biological Sciences at the University of Montana, Missoula. Dr. Woods serves as a reviewer for numerous journals including \u003ci\u003eJournal of Experimental Biology\u003c\/i\u003e, \u003ci\u003ePhysiological and Biochemical Zoology\u003c\/i\u003e, \u003ci\u003eProceedings of the Royal Society of London B\u003c\/i\u003e, \u003ci\u003eFunctional Ecology\u003c\/i\u003e, and \u003ci\u003eAmerican Naturalist\u003c\/i\u003e. In 2009 Dr. Woods received one of the National Science Foundation's prestigious CAREER awards in support of his research on leaf microclimates and plant-insect interactions.\u003c\/p\u003e","brand":"Wiley-Blackwell","offers":[{"title":"Default Title","offer_id":47989438775525,"sku":"NP9781118398784","price":121.5,"currency_code":"USD","in_stock":false}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/1842\/7735\/files\/9781118398784.jpg?v=1761784103","url":"https:\/\/k12savings.com\/es\/products\/integrative-organismal-biology-isbn-9781118398784","provider":"K12savings","version":"1.0","type":"link"}