{"product_id":"inflammatory-bowel-diseases-isbn-9781119077602","title":"Inflammatory Bowel Diseases","description":"\u003cp\u003e\u003cb\u003eInflammatory Bowel Diseases: A Clinician’s Guide \u003c\/b\u003eprovides practical guidance for the diagnosis and management of those suspected or known to have one of the forms of these complex diseases. It is perfect both for gastroenterology trainees learning to care for these patients and the experienced physician as a concise and practical resource for day to day use.\u003c\/p\u003e Written by the experts, \u003cb\u003eInflammatory Bowel Diseases: A Clinician’s Guide\u003c\/b\u003e is an essential tool for all gastroenterologists managing patients with inflammatory bowel disease. \u003cp\u003ePreface ix\u003c\/p\u003e \u003cp\u003e\u003cb\u003eSection I Pathogenesis and Clinical Features 1\u003c\/b\u003e\u003c\/p\u003e \u003cp\u003e\u003cb\u003e1 Epidemiology and Pathogenesis 3\u003c\/b\u003e\u003c\/p\u003e \u003cp\u003eClinical Take Home Messages 3\u003c\/p\u003e \u003cp\u003eEpidemiology 3\u003c\/p\u003e \u003cp\u003ePathogenesis 6\u003c\/p\u003e \u003cp\u003eGenetics 6\u003c\/p\u003e \u003cp\u003eMicrobiome 8\u003c\/p\u003e \u003cp\u003eEnvironmental Triggers 9\u003c\/p\u003e \u003cp\u003eCase Studies and Multiple Choice Questions 12\u003c\/p\u003e \u003cp\u003eReferences 13\u003c\/p\u003e \u003cp\u003eAnswers to Questions 15\u003c\/p\u003e \u003cp\u003e\u003cb\u003e2 Clinical Features and Diagnosis of Crohn’s Disease 17\u003c\/b\u003e\u003c\/p\u003e \u003cp\u003eClinical Take Home Messages 17\u003c\/p\u003e \u003cp\u003eClinical Features 19\u003c\/p\u003e \u003cp\u003eDisease Course and Natural History 20\u003c\/p\u003e \u003cp\u003eDiagnosis 21\u003c\/p\u003e \u003cp\u003eHistory and Physical Examination 21\u003c\/p\u003e \u003cp\u003eLaboratory Investigations 22\u003c\/p\u003e \u003cp\u003eSerologic Markers 23\u003c\/p\u003e \u003cp\u003eEndoscopy 23\u003c\/p\u003e \u003cp\u003eHistology 25\u003c\/p\u003e \u003cp\u003eImaging Studies 25\u003c\/p\u003e \u003cp\u003eCase Studies and Multiple Choice Questions 27\u003c\/p\u003e \u003cp\u003eReferences 28\u003c\/p\u003e \u003cp\u003eAnswers to Questions 31\u003c\/p\u003e \u003cp\u003e\u003cb\u003e3 Clinical Features and Diagnosis of Ulcerative Colitis 33\u003c\/b\u003e\u003c\/p\u003e \u003cp\u003eClinical Take Home Messages 33\u003c\/p\u003e \u003cp\u003eClinical Features 34\u003c\/p\u003e \u003cp\u003eDisease Course and Natural History 35\u003c\/p\u003e \u003cp\u003eDiagnosis 35\u003c\/p\u003e \u003cp\u003eHistory and Physical Examination 36\u003c\/p\u003e \u003cp\u003eLaboratory Investigations 36\u003c\/p\u003e \u003cp\u003eSerologic Markers 37\u003c\/p\u003e \u003cp\u003eEndoscopy 37\u003c\/p\u003e \u003cp\u003eHistology 39\u003c\/p\u003e \u003cp\u003eImaging Studies 40\u003c\/p\u003e \u003cp\u003eDifferential Diagnosis (UC and CD) 40\u003c\/p\u003e \u003cp\u003eCase Studies and Multiple Choice Questions 44\u003c\/p\u003e \u003cp\u003eReferences 45\u003c\/p\u003e \u003cp\u003eAnswers to Questions 47\u003c\/p\u003e \u003cp\u003e\u003cb\u003e4 Extraintestinal Manifestations of Inflammatory Bowel Diseases 49\u003c\/b\u003e\u003c\/p\u003e \u003cp\u003eClinical Take Home Messages 49\u003c\/p\u003e \u003cp\u003eArthritis and Arthropathy 50\u003c\/p\u003e \u003cp\u003eMetabolic Bone Disease 51\u003c\/p\u003e \u003cp\u003eCutaneous Manifestations 52\u003c\/p\u003e \u003cp\u003eHepatobiliary Manifestations 53\u003c\/p\u003e \u003cp\u003eOphthalmologic Manifestations 55\u003c\/p\u003e \u003cp\u003eRenal Complications 55\u003c\/p\u003e \u003cp\u003eThromboembolic and Cardiovascular Complications 56\u003c\/p\u003e \u003cp\u003eCase Studies and Multiple Choice Questions 57\u003c\/p\u003e \u003cp\u003eReferences 58\u003c\/p\u003e \u003cp\u003eAnswers to Questions 61\u003c\/p\u003e \u003cp\u003e\u003cb\u003eSection II Therapeutic Agents 63\u003c\/b\u003e\u003c\/p\u003e \u003cp\u003e\u003cb\u003e5 Aminosalicylates 65\u003c\/b\u003e\u003c\/p\u003e \u003cp\u003eClinical Take Home Messages 65\u003c\/p\u003e \u003cp\u003eEfficacy in Ulcerative Colitis 66\u003c\/p\u003e \u003cp\u003eEfficacy in Crohn’s Disease 68\u003c\/p\u003e \u003cp\u003eSafety 68\u003c\/p\u003e \u003cp\u003eMultiple Choice Questions 70\u003c\/p\u003e \u003cp\u003eReferences 71\u003c\/p\u003e \u003cp\u003eAnswers to Questions 73\u003c\/p\u003e \u003cp\u003e\u003cb\u003e6 Corticosteroids 75\u003c\/b\u003e\u003c\/p\u003e \u003cp\u003eClinical Take Home Messages 75\u003c\/p\u003e \u003cp\u003eEfficacy in Ulcerative Colitis 76\u003c\/p\u003e \u003cp\u003eEfficacy in Crohn’s Disease 77\u003c\/p\u003e \u003cp\u003eSafety 78\u003c\/p\u003e \u003cp\u003eCase Studies and Multiple Choice Questions 80\u003c\/p\u003e \u003cp\u003eReferences 81\u003c\/p\u003e \u003cp\u003eAnswers to Questions 83\u003c\/p\u003e \u003cp\u003e\u003cb\u003e7 Immunomodulators 85\u003c\/b\u003e\u003c\/p\u003e \u003cp\u003eClinical Take Home Messages 85\u003c\/p\u003e \u003cp\u003eThiopurines 85\u003c\/p\u003e \u003cp\u003eEfficacy in Ulcerative Colitis 87\u003c\/p\u003e \u003cp\u003eEfficacy in Crohn’s Disease 88\u003c\/p\u003e \u003cp\u003eSafety 89\u003c\/p\u003e \u003cp\u003eMethotrexate 90\u003c\/p\u003e \u003cp\u003eEfficacy in Ulcerative Colitis 90\u003c\/p\u003e \u003cp\u003eEfficacy in Crohn’s Disease 91\u003c\/p\u003e \u003cp\u003eSafety 91\u003c\/p\u003e \u003cp\u003eCalcineurin Inhibitors 91\u003c\/p\u003e \u003cp\u003eEfficacy in Ulcerative Colitis 91\u003c\/p\u003e \u003cp\u003eEfficacy in Crohn’s Disease 93\u003c\/p\u003e \u003cp\u003eCase Studies and Multiple Choice Questions 94\u003c\/p\u003e \u003cp\u003eReferences 95\u003c\/p\u003e \u003cp\u003eAnswers to Questions 99\u003c\/p\u003e \u003cp\u003e\u003cb\u003e8 Biologic Therapies 101\u003c\/b\u003e\u003c\/p\u003e \u003cp\u003eClinical Take Home Messages 101\u003c\/p\u003e \u003cp\u003eInfliximab 102\u003c\/p\u003e \u003cp\u003eEfficacy in Ulcerative Colitis 102\u003c\/p\u003e \u003cp\u003eEfficacy in Crohn’s Disease 105\u003c\/p\u003e \u003cp\u003eSafety 108\u003c\/p\u003e \u003cp\u003eAdalimumab 110\u003c\/p\u003e \u003cp\u003eEfficacy in Ulcerative Colitis 110\u003c\/p\u003e \u003cp\u003eEfficacy in Crohn’s Disease 111\u003c\/p\u003e \u003cp\u003eCertolizumab Pegol 112\u003c\/p\u003e \u003cp\u003eEfficacy in Crohn’s Disease 113\u003c\/p\u003e \u003cp\u003eNewer Therapies 115\u003c\/p\u003e \u003cp\u003eCase Studies and Multiple Choice Questions 116\u003c\/p\u003e \u003cp\u003eReferences 117\u003c\/p\u003e \u003cp\u003eAnswers to Questions 121\u003c\/p\u003e \u003cp\u003e\u003cb\u003e9 Antibiotics 123\u003c\/b\u003e\u003c\/p\u003e \u003cp\u003eClinical Take Home Messages 123\u003c\/p\u003e \u003cp\u003eEfficacy in Ulcerative Colitis 123\u003c\/p\u003e \u003cp\u003eEfficacy in Crohn’s Disease 124\u003c\/p\u003e \u003cp\u003eOther Microbial Modification Methods – Probiotics and Fecal Microbiota Transplantation 125\u003c\/p\u003e \u003cp\u003eMultiple Choice Questions 126\u003c\/p\u003e \u003cp\u003eReferences 127\u003c\/p\u003e \u003cp\u003eAnswers to Questions 129\u003c\/p\u003e \u003cp\u003e\u003cb\u003eSection III Management 131\u003c\/b\u003e\u003c\/p\u003e \u003cp\u003e\u003cb\u003e10 Medical Management of Ulcerative Colitis 133\u003c\/b\u003e\u003c\/p\u003e \u003cp\u003eClinical Take Home Messages 133\u003c\/p\u003e \u003cp\u003eAssessment of Extent, Activity, and Severity 133\u003c\/p\u003e \u003cp\u003eLimited Colitis – Proctitis, Proctosigmoiditis, and Left‐sided Colitis 135\u003c\/p\u003e \u003cp\u003ePancolitis 136\u003c\/p\u003e \u003cp\u003eMild to Moderate Disease 137\u003c\/p\u003e \u003cp\u003eModerate to Severe Disease 138\u003c\/p\u003e \u003cp\u003eSevere Disease 140\u003c\/p\u003e \u003cp\u003eCase Studies and Multiple Choice Questions 142\u003c\/p\u003e \u003cp\u003eReferences 144\u003c\/p\u003e \u003cp\u003eAnswers to Questions 146\u003c\/p\u003e \u003cp\u003e\u003cb\u003e11 Medical Management of Crohn’s Disease 149\u003c\/b\u003e\u003c\/p\u003e \u003cp\u003eClinical Take Home Messages 149\u003c\/p\u003e \u003cp\u003eMild to Moderate Disease 150\u003c\/p\u003e \u003cp\u003eModerate to Severe Disease 151\u003c\/p\u003e \u003cp\u003eCase Studies and Multiple Choice Questions 154\u003c\/p\u003e \u003cp\u003eReferences 156\u003c\/p\u003e \u003cp\u003eAnswers to Questions 157\u003c\/p\u003e \u003cp\u003e\u003cb\u003e12 Surgical Management of Inflammatory Bowel Diseases 159\u003c\/b\u003e\u003c\/p\u003e \u003cp\u003eClinical Take Home Messages 159\u003c\/p\u003e \u003cp\u003eSurgery for Ulcerative Colitis 159\u003c\/p\u003e \u003cp\u003ePouch‐related Complications in Ulcerative Colitis 161\u003c\/p\u003e \u003cp\u003eSurgery for Crohn’s Disease 163\u003c\/p\u003e \u003cp\u003eProphylaxis for Prevention of Postoperative Recurrence in Crohn’s Disease 164\u003c\/p\u003e \u003cp\u003eCase Studies and Multiple Choice Questions 167\u003c\/p\u003e \u003cp\u003eReferences 168\u003c\/p\u003e \u003cp\u003eRecommended Reading 169\u003c\/p\u003e \u003cp\u003eAnswers to Questions 170\u003c\/p\u003e \u003cp\u003e\u003cb\u003e13 Complications of Inflammatory Bowel Diseases 171\u003c\/b\u003e\u003c\/p\u003e \u003cp\u003eClinical Take Home Messages 171\u003c\/p\u003e \u003cp\u003eComplications of Ulcerative Colitis 172\u003c\/p\u003e \u003cp\u003eToxic Megacolon and Perforation 172\u003c\/p\u003e \u003cp\u003eColonic Strictures 173\u003c\/p\u003e \u003cp\u003eClostridium difficile and Cytomegalovirus Colitis 173\u003c\/p\u003e \u003cp\u003eColorectal Dysplasia and Cancer 174\u003c\/p\u003e \u003cp\u003eMagnitude and Risk Factors 174\u003c\/p\u003e \u003cp\u003eSurveillance for Dysplasia and Cancer 175\u003c\/p\u003e \u003cp\u003eManagement of Dysplasia 175\u003c\/p\u003e \u003cp\u003eChemoprevention 176\u003c\/p\u003e \u003cp\u003eComplications of Crohn’s Disease 176\u003c\/p\u003e \u003cp\u003eFibrostenosis and Strictures 176\u003c\/p\u003e \u003cp\u003eAbscesses 177\u003c\/p\u003e \u003cp\u003eFistulizing Crohn’s Disease 178\u003c\/p\u003e \u003cp\u003eSmall‐bowel Cancer 181\u003c\/p\u003e \u003cp\u003eCase Studies and Multiple Choice Questions 182\u003c\/p\u003e \u003cp\u003eReferences 184\u003c\/p\u003e \u003cp\u003eAnswers to Questions 187\u003c\/p\u003e \u003cp\u003e\u003cb\u003eSection IV Special Considerations 189\u003c\/b\u003e\u003c\/p\u003e \u003cp\u003e\u003cb\u003e14 Nutrition in Inflammatory Bowel Diseases 191\u003c\/b\u003e\u003c\/p\u003e \u003cp\u003eClinical Take Home Messages 191\u003c\/p\u003e \u003cp\u003eMalnutrition and Micronutrient Deficiencies 191\u003c\/p\u003e \u003cp\u003eDietary Therapies for Inflammatory Bowel Diseases 193\u003c\/p\u003e \u003cp\u003eCase Studies and Multiple Choice Questions 194\u003c\/p\u003e \u003cp\u003eReferences 195\u003c\/p\u003e \u003cp\u003eAnswers to Questions 197\u003c\/p\u003e \u003cp\u003e\u003cb\u003e15 Pregnancy, Conception, and Childbirth 199 \u003c\/b\u003e\u003c\/p\u003e \u003cp\u003eClinical Take Home Messages 199\u003c\/p\u003e \u003cp\u003eFertility 199\u003c\/p\u003e \u003cp\u003eEffect of Pregnancy on Disease 200\u003c\/p\u003e \u003cp\u003eEffect of Disease on Pregnancy 200\u003c\/p\u003e \u003cp\u003eMaternal Medication Use During Pregnancy 201\u003c\/p\u003e \u003cp\u003ePaternal Medication Use 203\u003c\/p\u003e \u003cp\u003eInheritance 203\u003c\/p\u003e \u003cp\u003eCase Studies and Multiple Choice Questions 204\u003c\/p\u003e \u003cp\u003eReferences 205\u003c\/p\u003e \u003cp\u003eAnswers to Questions 207\u003c\/p\u003e \u003cp\u003e\u003cb\u003e16 Inflammatory Bowel Disease During Childhood and Adolescence 209\u003c\/b\u003e\u003c\/p\u003e \u003cp\u003eClinical Take Home Messages 209\u003c\/p\u003e \u003cp\u003eEpidemiology and Clinical Features 209\u003c\/p\u003e \u003cp\u003eTreatment of Pediatric Inflammatory Bowel Disease 210\u003c\/p\u003e \u003cp\u003eVery Early‐onset Inflammatory Bowel Disease 211\u003c\/p\u003e \u003cp\u003eTransition of Care in Pediatric Crohn’s Disease 211\u003c\/p\u003e \u003cp\u003eCase Studies and Multiple Choice Questions 213\u003c\/p\u003e \u003cp\u003eReferences 214\u003c\/p\u003e \u003cp\u003eAnswers to Questions 216\u003c\/p\u003e \u003cp\u003eIndex 217\u003c\/p\u003e \u003cp\u003e“This is a valuable book that everybody taking care of IBD patients should have. It is very concise but at the same time very complete” \u003cb\u003eHenrique Fernandez, MD, FACP, Parkview Medical Center on behalf of Doody’s\u003c\/b\u003e\u003c\/p\u003e \u003cp\u003e\u003cb\u003eAshwin N. Ananthakrishnan\u003c\/b\u003e \u003cb\u003eMD, MPH\u003c\/b\u003e, Assistant Professor of Medicine, Harvard Medical School; Director, Crohn’s and Colitis Center, Massachusetts General Hospital, Boston, MA, USA.\u003c\/p\u003e \u003cp\u003e\u003cb\u003eRamnik J. Xavier MD\u003c\/b\u003e, Kurt Isselbacher Professor of Medicine, Harvard Medical School; Chief of Gastroenterology, Massachusetts General Hospital; Institute Member, Broad Institute of MIT and Harvard, Boston, MA, USA.\u003c\/p\u003e \u003cp\u003e\u003cb\u003eDaniel K. Podolsky MD\u003c\/b\u003e, President, University of Texas Southwestern Medical Center; Professor of Internal Medicine, University of Texas Southwestern Medical School, Dallas, TX, USA.\u003c\/p\u003e \u003cp\u003e\u003ci\u003eInflammatory Bowel Diseases: A Clinician’s Guide\u003c\/i\u003e provides practical guidance for the diagnosis and management of those suspected or known to have one of the forms of these complex diseases. It is perfect both for gastroenterology trainees learning to care for these patients and the experienced physician, as a concise and practical resource for day-to-day use.\u003c\/p\u003e \u003cp\u003e• Focuses primarily on the clinical management of inflammatory bowel diseases\u003cbr\u003e• Key points and clear step-by-step diagnosis and management flowcharts throughout\u003cbr\u003e• Written by a trio of leading IBD specialists, including the Editor-in-Chief of Yamada’s Textbook of Gastroenterology\u003cbr\u003e• Real-life case studies in all relevant chapters – perfect for GI trainees to learn from\u003cbr\u003e• Self-assessment MCQs related to the case studies, all written to the level of GI Board exams\u003c\/p\u003e \u003cp\u003eWritten by the experts, Inflammatory Bowel Diseases: A Clinician’s Guide is an essential tool for all gastroenterologists managing patients with inflammatory bowel diseases.\u003c\/p\u003e \u003cp\u003ewww.wiley.com\/go\/gastroenterology\u003c\/p\u003e","brand":"Wiley-Blackwell","offers":[{"title":"Default Title","offer_id":47989420359909,"sku":"NP9781119077602","price":166.95,"currency_code":"USD","in_stock":false}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/1842\/7735\/files\/9781119077602.jpg?v=1761784034","url":"https:\/\/k12savings.com\/es\/products\/inflammatory-bowel-diseases-isbn-9781119077602","provider":"K12savings","version":"1.0","type":"link"}