{"product_id":"infections-causing-human-cancer-isbn-9783527329779","title":"Infections Causing Human Cancer","description":"Infections must be thought as one of the most important, if not the most important, risk factors for cancer development in humans. Approximately 15-20% of all cases of cancer around the world are caused by viruses. The\u003cbr\u003e establishment of a causal relationship between the presence of specific infective agents and certain types of human cancer represents a key step in the development of novel therapeutic and preventive strategies.\u003cbr\u003e \u003cbr\u003e In this book, Professor zur Hausen (Nobel Prize in Physiology\/Medicine 2008) provides a thorough and comprehensive overview on carcinogenic infective agents -- viruses, bacteria, parasites and protozoons -- as well as their corresponding transforming capacities and mechanisms. The result is an invaluable and instructive reference for all oncologists, microbiologists and molecular biologists working in the area of infections and cancer.\u003cbr\u003e \u003cbr\u003e The author was among the first scientists to reveal the cervical cancer-inducing mechanisms of human papilloma viruses and isolated HPV16 and HPV18, and, as early as 1976, published the hypothesis that wart viruses\u003cbr\u003e play a role in the development of this type of cancer. HISTORICAL REVIEW\u003cbr\u003e The Early Period (1898-1911)\u003cbr\u003e Frustration and Successes (1912-1950)\u003cbr\u003e The Period from 1950 to 1965\u003cbr\u003e A First Human Tumor Virus?\u003cbr\u003e The Difficult 1970s\u003cbr\u003e The Re-emergence of a Concept\u003cbr\u003e THE QUEST FOR CAUSALITY\u003cbr\u003e Infectious Agents as Direct Carcinogens\u003cbr\u003e Infectious Agents as Indirect Carcinogens\u003cbr\u003e TUMORS LINKED TO INFECTIONS -\u003cbr\u003e SOME GENERAL ASPECTS\u003cbr\u003e Tumor Types Linked to Infections\u003cbr\u003e Global Contributions of Infections to Human Cancer\u003cbr\u003e Host Interactions with Potentially Carcinogenic Infections\u003cbr\u003e HERPESVIRUSES AND ONCOGENESIS\u003cbr\u003e Alphaherpesviridae\u003cbr\u003e Betaherpesviridae\u003cbr\u003e Gammaherpesviridae\u003cbr\u003e PAPILLOMAVIRUSES -\u003cbr\u003e A MAJOR CAUSE OF HUMAN CANCERS\u003cbr\u003e Introduction\u003cbr\u003e Concept of Viral Interfering Cascades\u003cbr\u003e Cancers Linked to HPV Infections\u003cbr\u003e Role of Co-factors\u003cbr\u003e Preventive Vaccination\u003cbr\u003e Therapeutic Vaccination\u003cbr\u003e Therapy\u003cbr\u003e HEPADNAVIRUS FAMILY\u003cbr\u003e Hepatitis B Virus\u003cbr\u003e Animal Hepadnaviruses\u003cbr\u003e FLAVIVIRUS FAMILY\u003cbr\u003e Hepatitis C Virus\u003cbr\u003e RETROVIRUS FAMILY\u003cbr\u003e Human T-lymphotropic Retroviruses 1 (HTLV-1)\u003cbr\u003e Human T-lymphotropic Retroviruses 2 (HTLV-2)\u003cbr\u003e Human Endogenous Retroviruses\u003cbr\u003e Gibbon Ape Leukaemia Virus and Simian Sarcoma Virus\u003cbr\u003e OTHER VIRUS INFECTIONS POSSIBLY INVOLVED IN HUMAN CANCERS\u003cbr\u003e Polyomaviruses (JC, BK and SV40)\u003cbr\u003e HELICOBACTER, CHRONIC INFLAMMATION AND CANCER\u003cbr\u003e Discovery, Taxonomy and Genomics\u003cbr\u003e Life Cycle, Specificity, and Virulence Determinants in Cancer Development\u003cbr\u003e Prevention of H. Pylori Induced Cancer\u003cbr\u003e Animal Models\u003cbr\u003e Virulence Determinants of Enterohepatic Helicobacter Spp\u003cbr\u003e Enterohepatic Helicobacter Spp. -\u003cbr\u003e Are they Cocarcinogens?\u003cbr\u003e PARASITES AND HUMAN CANCER\u003cbr\u003e Schistosomiasis\u003cbr\u003e Infection with Liver Flukes (Opisthorchis Viverrini, O. Felineus, Clonorchis Sinensis)\u003cbr\u003e CANCERS WITH A POSSIBLE INFECTIOUS ETIOLOGY\u003cbr\u003e Leukemias and Lymphomas\u003cbr\u003e Human Breast Cancer\u003cbr\u003e Other Human Cancers Possibly Linked to Infectious Events \"You should consider purchasing it.\" Lab Times\u003cbr\u003e \"Fachleute wie Harald zur Hausen und Experten der Weltgesundheitsorganisation (WHO) schätzen übereinstimmend, dass 20 Prozent aller Krebserkrankungen durch Infektionen entstehen. Der Tumorvirologe zur Hausen leitete 20 Jahre lang das Deutsche Krebsforschungszentrum in Heidelberg. Der 70-jährige, noch immer hoch aktive Forscher wurde wiederholt für den Nobelpreis nominiert. Nun fasst er in einem 500-seitigen Buch ... den Wissensstand zusammen.\" Die Zeit\u003cbr\u003e \u003cbr\u003e \"...einen umfassenden Statusbericht über den Zusammenhang zwischen Krebs und Infektionskrankheiten...bietet allen Mikrobiologen, Onkologen sowie Ärzten und Naturwissenschaftlern, welche auf dem Gebiet Infektionen arbeiten, ein wertvolles Nachschlagewerk. Der didaktisch geschickte, übersichtlich gegliederte  Aufbau ermöglicht einen leichten Einstieg. Von dem wissenschaftlichen, auf eigener Erfahrung begründeten Tiefgang können sogar die anspruchsvollsten Leser profitieren.\" Ärzte privat\u003cbr\u003e \u003cbr\u003e \"Insgesamt liefert dieses Buch einen hervorragenden Überblick über den aktuellen Kenntnisstand zu tumorauslösenden Infektionen. Der Autor hat sehr viel Wissen zusammengetragen und es verstanden, dieses sehr klar zu präsentieren.\" Pharmazie in unserer Zeit\u003cbr\u003e \u003cbr\u003e \"Nimmt man das Buch in die Hand, wundert man sich zunächst, dass dies offensichtlich kein \"Gemeinschaftswerk\" zahlreicher Wissenschaftler unter der Federführung eines oder mehrerer Herausgeber ist, sondern dass tatsächlich Prof. zur Hausen, der frühere wissenschaftliche Direktor des Deutschen Krebsforschungszentrums, seinen Ruhestand dazu genutzt aht, eine Gesamtschau des derzeitigen Wissens zusammenzustellen. Nur eines der insgesamt 12 Kapitel, nämlich das zur Rolle von Heliocobacter-Arten bei chronischen Entzündungen und Krebs, wurde von Wossenschaftlern von der Havard University beigetragen.\" Pharmazie in unserer Zeit\u003cbr\u003e From 1983 until his retirement in 2003, Harald zur Hausen acted as chairman of the management board and scientific director of the German Cancer Research Center in Heidelberg until his retirement in. Previously he worked at a number of different universities in the USA and Germany. Professor zur Hausen has served on a large number of different scientific and policy bodies in many different countries including the European Board of Directors of HUGO, the International Scientific Advisory Committee of the French National Cancer Institute and Vice-Chairman of the German American Academic Council. \u003cbr\u003e \u003cbr\u003e In 2008 Professor zur Hausen was awarded the Nobel Prize in Physiology\/Medicine for his research on the relationship between infections and cancer. Among his many other awards, he has held the Robert Koch Award, the Charles S. Mott Prize of the General Motors Cancer Research Foundation, the Paul Ehrlich and Ludwig Darmstaedter Award, the German Cancer Award, and the Federal Order of Merit, as well as six honorary degrees and seven visiting professorships. \u003cbr\u003e During the past 35 years, the author of this work and his co-workers initially found Epstein-Barr virus DNA in Burkitt's lymphomas and nasopharyngeal cancer and made the connection between HPV infection and cervical cancer. It was also during this period and subsequently that scientists all over the world discovered tumor-inducing bacteria, viruses, parasites, and protozoa, opening up entirely new prospects for the prevention and treatment of infection-induced cancer by vaccination.\u003cbr\u003e Adopting a unifying concept and a consistent structure for the individual chapters, Professor zur Hausen provides a thorough and comprehensive overview on cancer-inducing infective agents - viruses, bacteria and parasites - and their corresponding transforming capacities and mechanisms. He does not cover the structure and molecular biology of the agents presented in great detail, but rather concentrates on those aspects that link the respective agents to human oncogenesis. As such, an extensive bibliography after each chapter permits further studies on the subject. \u003cbr\u003e \u003cbr\u003e With a chapter on Helicobacter written by James Fox and his colleagues at Harvard University, this is an invaluable and instructive reference for all oncologists, microbiologists and molecular biologists working in the area of infections and cancer.\u003cbr\u003e \u003cbr\u003e \u003cbr\u003e Harald zur Hausen studied medicine at the Universities of Bonn, Hamburg and Dusseldorf, gaining his MD in 1960. He was a research fellow at the University of Dusseldorf and the Children's Hospital of Philadelphia, before being appointed assistant professor at the University of Pennsylvania in 1968. He joined the University of Wurzburg one year later, initially as a senior scientist and then as a private lecturer. From 1972 to 1977 he was Professor of Virology at the University of Erlangen-Nurnberg, and then at the University of Freiburg until 1983. Thereafter, he was appointed Scientific Director of the German Cancer Research Center in Heidelberg until his retirement in 2003.\u003cbr\u003e Professor zur Hausen has been a member of various research organizations, academies of science, and scientific boards. He was President of OECI, Vice-Chairman of the German American Academic Council and Vice-President of the Helmholtz Society of German National Research Centers. Among others, he received the Robert Koch Award, the Charles S. Mott Prize of the General Motors Cancer Research Foundation, the Paul Ehrlich and Ludwig Darmstaedter Award, the German Cancer Award, the Prince Mahidol Award of Thailand and the Federal Order of Merit, as well as six honorary degrees in six different countries. He is Editor-in-Chief of the International Journal of Cancer and on the editorial board of several scientific journals and has organized or co-organized a number of international meetings.","brand":"Wiley-Blackwell","offers":[{"title":"Default Title","offer_id":47989419409637,"sku":"NP9783527329779","price":77.95,"currency_code":"USD","in_stock":false}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/1842\/7735\/files\/9783527329779.jpg?v=1761784032","url":"https:\/\/k12savings.com\/es\/products\/infections-causing-human-cancer-isbn-9783527329779","provider":"K12savings","version":"1.0","type":"link"}