{"product_id":"immunotherapy-in-transplantation-isbn-9781405182713","title":"Immunotherapy in Transplantation","description":"This comprehensive reference source will benefit all transplant specialists working with pharmacologic and biologic agents that modulate the immune system. Compiled by a team of world-renowned editors and contributors covering the fields of transplantation, nephrology, pharmacology, and immunology, the book covers all anti-rejection drugs according to a set template and includes the efficacy of each for specific diseases.  List of Contributors.  \u003cp\u003ePreface.\u003c\/p\u003e \u003cp\u003e\u003cb\u003eSection 1: Transplantation Immunobiology.\u003c\/b\u003e\u003c\/p\u003e \u003cp\u003e1 The Immune Response to a Transplanted Organ: An Overview (\u003ci\u003eFadi G. Lakkis\u003c\/i\u003e).\u003c\/p\u003e \u003cp\u003e2 Antigen Presentation in Transplantation (\u003ci\u003eMartin H. Oberbarnscheidt and Fadi G. Lakkis\u003c\/i\u003e).\u003c\/p\u003e \u003cp\u003e3 The T Cell Response to Transplantation Antigens (\u003ci\u003eDidier A. Mandelbrot, Bryna Burrell, Mohamed H. Sayegh and Peter S. Heeger\u003c\/i\u003e).\u003c\/p\u003e \u003cp\u003e4 The B Cell Response to Transplantation Antigens (\u003ci\u003eRoger Sciammas, Anita S. Chong, Robert B. Colvin\u003c\/i\u003e).\u003c\/p\u003e \u003cp\u003e5  The Innate Response to a Transplanted Organ (\u003ci\u003eDaniel R. Goldstein and Laurence A. Turka\u003c\/i\u003e).\u003c\/p\u003e \u003cp\u003e6 Regulation of the Alloimmune Response (\u003ci\u003eKathryn J Wood and Terry B Strom\u003c\/i\u003e).\u003c\/p\u003e \u003cp\u003e\u003cb\u003eSection 2: Transplantation Clinical Pharmacology.\u003c\/b\u003e\u003c\/p\u003e \u003cp\u003e7 Pharmacokinetics (\u003ci\u003eRaman Venkataramanan\u003c\/i\u003e).\u003c\/p\u003e \u003cp\u003e8 Therapeutic Drug Monitoring for Immunosuppressive Agents (\u003ci\u003eMichael C. Milone and Leslie M. J. Shaw\u003c\/i\u003e).\u003c\/p\u003e \u003cp\u003e9 Pharmacometrics: Concepts and Applications to Drug Development (\u003ci\u003eMallika Lala and Jogarao V. S. Gobburu\u003c\/i\u003e).\u003c\/p\u003e \u003cp\u003e10 Pharmacogenomics and Organ Transplantation (\u003ci\u003eGilbert J. Burckart and Richard M. Watanabe\u003c\/i\u003e).\u003c\/p\u003e \u003cp\u003e11 Study Design\/process of development: Clinical studies (\u003ci\u003eRichard D. Mamelok\u003c\/i\u003e).\u003c\/p\u003e \u003cp\u003e\u003cb\u003eSection 3: Agents.\u003c\/b\u003e\u003c\/p\u003e \u003cp\u003e12 Corticosteroids (\u003ci\u003eOlivia Blume, Sarah E. Yost and Bruce Kaplan\u003c\/i\u003e).\u003c\/p\u003e \u003cp\u003e13 Azathioprine (\u003ci\u003eBarry J. Browne\u003c\/i\u003e).\u003c\/p\u003e \u003cp\u003e14 Pharmacokinetic and Pharmacodynamic Properties of Mycophenolate (\u003ci\u003eDavid Hager, Arjang Djamali, Bruce Kaplan\u003c\/i\u003e).\u003c\/p\u003e \u003cp\u003e15 Cyclosporine: Molecular Action to Clinical Therapeutics (\u003ci\u003eBradford Strijack and Paul A. Keown\u003c\/i\u003e).\u003c\/p\u003e \u003cp\u003e16 Tacrolimus (\u003ci\u003eWilliam E. Fitzsimmons\u003c\/i\u003e).\u003c\/p\u003e \u003cp\u003e17 Inhibitors of Mammalian Target of Rapamycin (\u003ci\u003eBarry D. Kahan\u003c\/i\u003e).\u003c\/p\u003e \u003cp\u003e18 Inhibitors Targeting JAK3 (\u003ci\u003eGary Chan, Paul S. Changelian\u003c\/i\u003e).\u003c\/p\u003e \u003cp\u003e19 Cyclophosphamide (\u003ci\u003eJohn J. Curtis\u003c\/i\u003e).\u003c\/p\u003e \u003cp\u003e20 Application of antisense technology in medicine (\u003ci\u003eStanislaw M. Stepkowski, Beata Mierzejewska, Frank C. Bennett\u003c\/i\u003e).\u003c\/p\u003e \u003cp\u003e21 The role of ganciclovir in transplantation (\u003ci\u003eLyndsey J. Bowman and Daniel C. Brennan\u003c\/i\u003e).\u003c\/p\u003e \u003cp\u003e22 Transplantation Immunotherapy with Anti-Thymocyte Globulin (ATG) (\u003ci\u003eJohn L. Dzuris, Christian Bloy, Melanie Ruzek, John M. Williams\u003c\/i\u003e).\u003c\/p\u003e \u003cp\u003e23 The Role of Alemtuzumab in Solid Organ Transplantation (\u003ci\u003eAvinash Agarwal, David  Bruno and Stuart J. Knechtle\u003c\/i\u003e).\u003c\/p\u003e \u003cp\u003e24 Rituximab, an anti-CD20 monoclonal antibody (\u003ci\u003eMark D. Pescovitz\u003c\/i\u003e).\u003c\/p\u003e \u003cp\u003e25 The Anti-Interleukin 2 Receptor Antibodies (\u003ci\u003eMuna Alnimri and Flavio Vincenti\u003c\/i\u003e).\u003c\/p\u003e \u003cp\u003e26 Infliximab\/ Anti-TNF (\u003ci\u003eMarina Vardanyan, Edward C. Parkin, Horacio L. Rodriguez Rilo\u003c\/i\u003e).\u003c\/p\u003e \u003cp\u003e27 CTLA4-Ig (\u003ci\u003eSarah E. Yost and Bruce Kaplan\u003c\/i\u003e).\u003c\/p\u003e \u003cp\u003e28 Combination and Adjuvant Therapies to Facilitate the Efficacy of Costimulatory Blockade (\u003ci\u003eSwetha K. Srinivasan, Helen L. Triemer, Allan D. Kirk\u003c\/i\u003e).\u003c\/p\u003e \u003cp\u003e29 Intravenous Immunoglobulin (IVIG) a Modulator of Immunity and Inflammation with Applications in Solid Organ Transplantation (\u003ci\u003eStanley C. Jordan, Mieko Toyoda, Joseph Kahwaji, Alice Peng and Ashley A. Vo\u003c\/i\u003e).\u003c\/p\u003e \u003cp\u003eIndex.\u003c\/p\u003e  \u003cp\u003e“Overall, the text is highly structured, well presented and applicable to transplant clinicians and pharmacologists in particular. . . . Those wishing to advance their understanding of transplant immunology, the technologies and techniques used for drug monitoring, the drug development pipeline and the basis for use of current agents in transplantation will find their interests more than satisfied.”  (\u003ci\u003eAmerican Journal of Transplantation\u003c\/i\u003e, 5 September 2013)\u003c\/p\u003e \u003cp\u003e“It will serve a clinician well as a focused reference for immunology and pharmacotherapy relevant to the transplant arena. It would be a welcome and useful addition to the medical or pharmaceutical library of a transplant professional or institution, albeit on the expensive side for a focused textbook.”  (\u003ci\u003eThe Annals of Pharmacotherapy\u003c\/i\u003e, 1 March 2013)\u003c\/p\u003e \u003cp\u003e“This comprehensive reference source will benefit all transplant specialists working with pharmacologic and biologic agents that modulate the immune system.”  (\u003ci\u003eEuropean Journal of Immunology\u003c\/i\u003e, 1 December 2012)\u003c\/p\u003e \u003cp\u003e“This is a decent review of transplant immunology that is helpful for the training practitioner. Given its systematic approach, it is easier to follow than other books on the subject.”  (\u003ci\u003eDoody’s\u003c\/i\u003e, 17 August 2012)\u003c\/p\u003e \u003cp\u003e \u003c\/p\u003e \u003cp\u003e \u003c\/p\u003e  \u003cp\u003e\u003cstrong\u003eBruce Kaplan\u003c\/strong\u003e, MD, Professor of Medicine, Surgery and Pharmacology, Co-Director UIC Transplant Center, University of Illinois at Chicago, USA and Adjunct Professor of Medicine, Applied Genomics Center, University of Alberta, Canada. \u003c\/p\u003e\u003cp\u003e\u003cstrong\u003eGilbert Burkhart\u003c\/strong\u003e, Pharm D, Department of Medicine, University of Southern California (USC), San Francisco, USA. \u003c\/p\u003e\u003cp\u003e\u003cstrong\u003ePhil Halloran\u003c\/strong\u003e, MD, PhD, Professor of Medicine, Director of Nephrology and Immunology, University of Alberta, Edmonton, Canada.\u003c\/p\u003e","brand":"Wiley-Blackwell","offers":[{"title":"Default Title","offer_id":47989403877605,"sku":"NP9781405182713","price":314.95,"currency_code":"USD","in_stock":false}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/1842\/7735\/files\/9781405182713.jpg?v=1761783977","url":"https:\/\/k12savings.com\/es\/products\/immunotherapy-in-transplantation-isbn-9781405182713","provider":"K12savings","version":"1.0","type":"link"}