{"product_id":"heterocyclic-chemistry-at-a-glance-isbn-9780470971215","title":"Heterocyclic Chemistry At A Glance","description":"This expanded second edition provides a concise overview of the main principles and reactions of heterocyclic chemistry for undergraduate students studying chemistry and related courses. Using a successful and student-friendly \"at a glance\" approach, this book helps the student grasp the essence of heterocyclic chemistry, ensuring that they can confidently use that knowledge when required. The chapters are thoroughly revised and updated with references to books and reviews; extra examples and student exercises with answers online; and color diagrams that emphasize exactly what is happening in the reaction chemistry depicted. \u003cp\u003eBiography v\u003c\/p\u003e \u003cp\u003eAbbreviations xii\u003c\/p\u003e \u003cp\u003eIntroduction to Second Edition xiv\u003c\/p\u003e \u003cp\u003e\u003cb\u003e1. Heterocyclic Nomenclature 1\u003c\/b\u003e\u003c\/p\u003e \u003cp\u003eSix-membered aromatic heterocycles 2\u003c\/p\u003e \u003cp\u003eFive-membered aromatic heterocycles 2\u003c\/p\u003e \u003cp\u003eNon-aromatic heterocycles 3\u003c\/p\u003e \u003cp\u003eSmall-ring heterocycles 3\u003c\/p\u003e \u003cp\u003e\u003cb\u003e2. Structures of Heteroaromatic Compounds 4\u003c\/b\u003e\u003c\/p\u003e \u003cp\u003eStructures of benzene and naphthalene 4\u003c\/p\u003e \u003cp\u003eStructures of pyridines and pyridiniums 5\u003c\/p\u003e \u003cp\u003eStructures of quinolines and isoquinolines 6\u003c\/p\u003e \u003cp\u003eStructures of diazines (illustrated using pyrimidine) 6\u003c\/p\u003e \u003cp\u003eStructures of pyrroles, thiophenes and furans 6\u003c\/p\u003e \u003cp\u003eStructure of indoles 8\u003c\/p\u003e \u003cp\u003eStructures of azoles (illustrated using imidazole) 8\u003c\/p\u003e \u003cp\u003e\u003cb\u003e3. Common Reaction Types in Heterocyclic Chemistry 9\u003c\/b\u003e\u003c\/p\u003e \u003cp\u003eIntroduction 9\u003c\/p\u003e \u003cp\u003eAcidity and basicity 9\u003c\/p\u003e \u003cp\u003eElectrophilic substitution of aromatic molecules 10\u003c\/p\u003e \u003cp\u003eNucleophilic substitution of aromatic molecules 13\u003c\/p\u003e \u003cp\u003eRadical substitution of heterocycles 14\u003c\/p\u003e \u003cp\u003e\u003ci\u003eC\u003c\/i\u003e-Metallated heterocycles as nucleophiles 15\u003c\/p\u003e \u003cp\u003eGeneration of \u003ci\u003eC\u003c\/i\u003e-metallated heterocycles 16\u003c\/p\u003e \u003cp\u003eDimethylformamide dimethyl acetal (DMFDMA) 17\u003c\/p\u003e \u003cp\u003eFormation and hydrolysis of imine\/enamine 18\u003c\/p\u003e \u003cp\u003eCommon synthetic equivalents of carbonyl compounds in ring synthesis 19\u003c\/p\u003e \u003cp\u003eCycloaddition reactions 19\u003c\/p\u003e \u003cp\u003e\u003cb\u003e4. Palladium in Heterocyclic Chemistry 21\u003c\/b\u003e\u003c\/p\u003e \u003cp\u003ePalladium(0)-catalysed (and related) reactions 21\u003c\/p\u003e \u003cp\u003eAddition to alkenes: the Heck reaction 26\u003c\/p\u003e \u003cp\u003eCarbonylation reactions 26\u003c\/p\u003e \u003cp\u003eCross-coupling reactions between heteroatom nucleophiles and halides – making carbon–heteroatom bonds 27\u003c\/p\u003e \u003cp\u003eTriflates as substrates for palladium-catalysed reactions 27\u003c\/p\u003e \u003cp\u003eMechanisms of palladium(0)-catalysed processes 28\u003c\/p\u003e \u003cp\u003eReactions involving electrophilic palladation 29\u003c\/p\u003e \u003cp\u003eCopper-catalysed amination 30\u003c\/p\u003e \u003cp\u003eSelectivity 31\u003c\/p\u003e \u003cp\u003e\u003cb\u003e5. Pyridines 33\u003c\/b\u003e\u003c\/p\u003e \u003cp\u003eElectrophilic addition to nitrogen 33\u003c\/p\u003e \u003cp\u003eElectrophilic substitution at carbon 34\u003c\/p\u003e \u003cp\u003eNucleophilic substitution 35\u003c\/p\u003e \u003cp\u003eNucleophilic addition to pyridinium salts 36\u003c\/p\u003e \u003cp\u003e\u003ci\u003eC\u003c\/i\u003e-metallated pyridines 37\u003c\/p\u003e \u003cp\u003ePalladium(0)-catalysed reactions 39\u003c\/p\u003e \u003cp\u003eOxidation and reduction 39\u003c\/p\u003e \u003cp\u003ePericyclic reactions 40\u003c\/p\u003e \u003cp\u003eAlkyl and carboxylic acid substituents 40\u003c\/p\u003e \u003cp\u003eOxygen substituents 41\u003c\/p\u003e \u003cp\u003e\u003ci\u003eN\u003c\/i\u003e-Oxides 42\u003c\/p\u003e \u003cp\u003eAmine substituents 43\u003c\/p\u003e \u003cp\u003eRing synthesis – disconnections 43\u003c\/p\u003e \u003cp\u003eSynthesis of pyridines from 1,5-dicarbonyl compounds 44\u003c\/p\u003e \u003cp\u003eSynthesis of pyridines from an aldehyde, two equivalents of a 1,3-dicarbonyl compound and ammonia 45\u003c\/p\u003e \u003cp\u003eSynthesis of pyridines from 1,3-dicarbonyl compounds and a C\u003csub\u003e2\u003c\/sub\u003eN unit 45\u003c\/p\u003e \u003cp\u003eExercises 47\u003c\/p\u003e \u003cp\u003e\u003cb\u003e6. Diazines 48\u003c\/b\u003e\u003c\/p\u003e \u003cp\u003eElectrophilic addition to nitrogen 49\u003c\/p\u003e \u003cp\u003eElectrophilic substitution at carbon 49\u003c\/p\u003e \u003cp\u003eNucleophilic substitution 50\u003c\/p\u003e \u003cp\u003eRadical substitution 52\u003c\/p\u003e \u003cp\u003e\u003ci\u003eC\u003c\/i\u003e-Metallated diazines 52\u003c\/p\u003e \u003cp\u003ePalladium(0)-catalysed reactions 53\u003c\/p\u003e \u003cp\u003ePericyclic reactions 54\u003c\/p\u003e \u003cp\u003eOxygen substituents 55\u003c\/p\u003e \u003cp\u003e\u003ci\u003eN\u003c\/i\u003e-Oxides 57\u003c\/p\u003e \u003cp\u003eAmine substituents 57\u003c\/p\u003e \u003cp\u003eRing synthesis – disconnections 58\u003c\/p\u003e \u003cp\u003eSynthesis of pyridazines from 1,4-dicarbonyl compounds 58\u003c\/p\u003e \u003cp\u003eSynthesis of pyrimidines from 1,3-dicarbonyl compounds 58\u003c\/p\u003e \u003cp\u003eSynthesis of pyrazines from 1,2-dicarbonyl compounds 59\u003c\/p\u003e \u003cp\u003eSynthesis of pyrazines from α-amino-carbonyl compounds 60\u003c\/p\u003e \u003cp\u003eBenzodiazines 60\u003c\/p\u003e \u003cp\u003eExercises 61\u003c\/p\u003e \u003cp\u003e\u003cb\u003e7. Quinolines and Isoquinolines 62\u003c\/b\u003e\u003c\/p\u003e \u003cp\u003eElectrophilic addition to nitrogen 62\u003c\/p\u003e \u003cp\u003eElectrophilic substitution at carbon 62\u003c\/p\u003e \u003cp\u003eNucleophilic substitution 63\u003c\/p\u003e \u003cp\u003eNucleophilic addition to quinolinium\/isoquinolinium salts 64\u003c\/p\u003e \u003cp\u003e\u003ci\u003eC\u003c\/i\u003e-Metallated quinolines and isoquinolines 65\u003c\/p\u003e \u003cp\u003ePalladium(0)-catalysed reactions 65\u003c\/p\u003e \u003cp\u003eOxidation and reduction 66\u003c\/p\u003e \u003cp\u003eAlkyl substituents 66\u003c\/p\u003e \u003cp\u003eOxygen substituents 67\u003c\/p\u003e \u003cp\u003e\u003ci\u003eN\u003c\/i\u003e-Oxides 67\u003c\/p\u003e \u003cp\u003eRing synthesis – disconnections 67\u003c\/p\u003e \u003cp\u003eSynthesis of quinolines from anilines 67\u003c\/p\u003e \u003cp\u003eSynthesis of quinolines from ortho-aminoaryl ketones or aldehydes 68\u003c\/p\u003e \u003cp\u003eSynthesis of isoquinolines from 2-arylethamines 69\u003c\/p\u003e \u003cp\u003eSynthesis of isoquinolines from aryl-aldehydes and an aminoacetaldehyde acetal 69\u003c\/p\u003e \u003cp\u003eSynthesis of isoquinolines from ortho-alkynyl aryl-aldehydes or corresponding imines 70\u003c\/p\u003e \u003cp\u003eExercises 70\u003c\/p\u003e \u003cp\u003e\u003cb\u003e8. Pyryliums, Benzopyryliums, Pyrones and Benzopyrones 71\u003c\/b\u003e\u003c\/p\u003e \u003cp\u003ePyrylium salts 71\u003c\/p\u003e \u003cp\u003eElectrophiles 71\u003c\/p\u003e \u003cp\u003eNucleophilic addition 71\u003c\/p\u003e \u003cp\u003eRing-opening reactions of 2\u003ci\u003eH\u003c\/i\u003e-pyrans 71\u003c\/p\u003e \u003cp\u003eOxygen substituents – pyrones and benzopyrones 73\u003c\/p\u003e \u003cp\u003eRing synthesis of pyryliums from 1,5-diketones 74\u003c\/p\u003e \u003cp\u003eRing synthesis of 4-pyrones from 1,3,5-triketones 75\u003c\/p\u003e \u003cp\u003eRing synthesis of 2-pyrones from 1,3-keto-aldehydes 75\u003c\/p\u003e \u003cp\u003eRing synthesis of 1-benzopyryliums, coumarins and chromones 76\u003c\/p\u003e \u003cp\u003eExercises 77\u003c\/p\u003e \u003cp\u003e\u003cb\u003e9. Pyrroles 78\u003c\/b\u003e\u003c\/p\u003e \u003cp\u003eElectrophilic substitution at carbon 78\u003c\/p\u003e \u003cp\u003e\u003ci\u003eN\u003c\/i\u003e-Deprotonation and \u003ci\u003eN\u003c\/i\u003e-metallated pyrroles 80\u003c\/p\u003e \u003cp\u003e\u003ci\u003eC\u003c\/i\u003e-Metallated pyrroles 80\u003c\/p\u003e \u003cp\u003ePalladium(0)-catalysed reactions 81\u003c\/p\u003e \u003cp\u003eOxidation and reduction 81\u003c\/p\u003e \u003cp\u003ePericyclic reactions 82\u003c\/p\u003e \u003cp\u003eReactivity of side-chain substituents 82\u003c\/p\u003e \u003cp\u003eThe ‘pigments of life’ 82\u003c\/p\u003e \u003cp\u003eRing synthesis – disconnections 83\u003c\/p\u003e \u003cp\u003eSynthesis of pyrroles from 1,4-dicarbonyl compounds 83\u003c\/p\u003e \u003cp\u003eSynthesis of pyrroles from α-amino-ketones 83\u003c\/p\u003e \u003cp\u003eSynthesis of pyrroles using isocyanides 84\u003c\/p\u003e \u003cp\u003eExercises 85\u003c\/p\u003e \u003cp\u003e10. Indoles 86\u003c\/p\u003e \u003cp\u003eElectrophilic substitution at carbon 86\u003c\/p\u003e \u003cp\u003e\u003ci\u003eN\u003c\/i\u003e-Deprotonation and \u003ci\u003eN\u003c\/i\u003e-metallated indoles 89\u003c\/p\u003e \u003cp\u003e\u003ci\u003eC\u003c\/i\u003e-Metallated indoles 90\u003c\/p\u003e \u003cp\u003ePalladium(0)-catalysed reactions 91\u003c\/p\u003e \u003cp\u003eOxidation and reduction 92\u003c\/p\u003e \u003cp\u003ePericyclic reactions 92\u003c\/p\u003e \u003cp\u003eReactivity of side-chain substituents 93\u003c\/p\u003e \u003cp\u003eOxygen substituents 94\u003c\/p\u003e \u003cp\u003eRing synthesis – disconnections 94\u003c\/p\u003e \u003cp\u003eSynthesis of indoles from arylhydrazones 94\u003c\/p\u003e \u003cp\u003eSynthesis of indoles from ortho-nitrotoluenes 95\u003c\/p\u003e \u003cp\u003eSynthesis of indoles from ortho-aminoaryl alkynes 96\u003c\/p\u003e \u003cp\u003eSynthesis of indoles from ortho-alkylaryl isocyanides 96\u003c\/p\u003e \u003cp\u003eSynthesis of indoles from ortho-acyl anilides 96\u003c\/p\u003e \u003cp\u003eSynthesis of isatins from anilines 97\u003c\/p\u003e \u003cp\u003eSynthesis of oxindoles from anilines 97\u003c\/p\u003e \u003cp\u003eSynthesis of indoxyls from anthranilic acids 97\u003c\/p\u003e \u003cp\u003eAzaindoles 97\u003c\/p\u003e \u003cp\u003eExercises 98\u003c\/p\u003e \u003cp\u003e\u003cb\u003e11. Furans and Thiophenes 99\u003c\/b\u003e\u003c\/p\u003e \u003cp\u003eElectrophilic substitution at carbon 99\u003c\/p\u003e \u003cp\u003e\u003ci\u003eC\u003c\/i\u003e-Metallated thiophenes and furans 101\u003c\/p\u003e \u003cp\u003ePalladium(0)-catalysed reactions 102\u003c\/p\u003e \u003cp\u003eOxidation and reduction 102\u003c\/p\u003e \u003cp\u003ePericyclic reactions 103\u003c\/p\u003e \u003cp\u003eOxygen substituents 104\u003c\/p\u003e \u003cp\u003eRing synthesis – disconnections 105\u003c\/p\u003e \u003cp\u003eSynthesis of furans and thiophenes from 1,4-dicarbonyl compounds 105\u003c\/p\u003e \u003cp\u003eExercises 106\u003c\/p\u003e \u003cp\u003e\u003cb\u003e12. 1,2-Azoles and 1,3-Azoles 107\u003c\/b\u003e\u003c\/p\u003e \u003cp\u003eIntroduction 107\u003c\/p\u003e \u003cp\u003eElectrophilic addition to N 107\u003c\/p\u003e \u003cp\u003eElectrophilic substitution at C 109\u003c\/p\u003e \u003cp\u003eNucleophilic substitution of halogen 110\u003c\/p\u003e \u003cp\u003e\u003ci\u003eN\u003c\/i\u003e-Deprotonation and \u003ci\u003eN\u003c\/i\u003e-metallated imidazoles and pyrazoles 110\u003c\/p\u003e \u003cp\u003e\u003ci\u003eC\u003c\/i\u003e-Metallated \u003ci\u003eN\u003c\/i\u003e-substituted imidazoles and pyrazoles, and \u003ci\u003eC\u003c\/i\u003e-metallated thiazoles and isothiazoles 111\u003c\/p\u003e \u003cp\u003e\u003ci\u003eC\u003c\/i\u003e-Deprotonation of oxazoles and isoxazoles 112\u003c\/p\u003e \u003cp\u003ePalladium(0)-catalysed reactions 113\u003c\/p\u003e \u003cp\u003e1,3-Azolium ylides 113\u003c\/p\u003e \u003cp\u003eReductions 114\u003c\/p\u003e \u003cp\u003ePericyclic reactions 114\u003c\/p\u003e \u003cp\u003eOxygen and amine substituents 115\u003c\/p\u003e \u003cp\u003e1,3-Azoles ring synthesis – disconnections 116\u003c\/p\u003e \u003cp\u003eSynthesis of thiazoles and imidazoles from α-halo-ketones 116\u003c\/p\u003e \u003cp\u003eSynthesis of 1,3-azoles from 1,4-dicarbonyl compounds 117\u003c\/p\u003e \u003cp\u003eSynthesis of 1,3-azoles using tosylmethyl isocyanide 118\u003c\/p\u003e \u003cp\u003eSynthesis of 1,3-azoles via dehydrogenation 118\u003c\/p\u003e \u003cp\u003e1,2-Azoles ring synthesis – disconnections 119\u003c\/p\u003e \u003cp\u003eSynthesis of pyrazoles and isoxazoles from 1,3-dicarbonyl compounds 119\u003c\/p\u003e \u003cp\u003eSynthesis of isoxazoles and pyrazoles from alkynes 120\u003c\/p\u003e \u003cp\u003eSynthesis of isothiazoles from α-amino α,β-unsaturated carbonyl compounds 121\u003c\/p\u003e \u003cp\u003eExercises 121\u003c\/p\u003e \u003cp\u003e\u003cb\u003e13. Purines 122\u003c\/b\u003e\u003c\/p\u003e \u003cp\u003eElectrophilic addition to nitrogen 124\u003c\/p\u003e \u003cp\u003eElectrophilic substitution at carbon 125\u003c\/p\u003e \u003cp\u003e\u003ci\u003eN\u003c\/i\u003e-Deprotonation and \u003ci\u003eN\u003c\/i\u003e-metallated purines 125\u003c\/p\u003e \u003cp\u003eOxidation 126\u003c\/p\u003e \u003cp\u003eNucleophilic substitution 126\u003c\/p\u003e \u003cp\u003e\u003ci\u003eC\u003c\/i\u003e-Metallated purines by direct deprotonation or halogen–metal exchange 128\u003c\/p\u003e \u003cp\u003ePalladium(0)-catalysed reactions 128\u003c\/p\u003e \u003cp\u003ePurines with oxygen and amine substituents 128\u003c\/p\u003e \u003cp\u003eRing synthesis – disconnections 130\u003c\/p\u003e \u003cp\u003eSynthesis of purines from 4,5-diaminopyrimidines 130\u003c\/p\u003e \u003cp\u003eSynthesis of purines from 5-aminoimidazole-4-carboxamide 131\u003c\/p\u003e \u003cp\u003e‘One-step syntheses’ 131\u003c\/p\u003e \u003cp\u003eExercises 131\u003c\/p\u003e \u003cp\u003e\u003cb\u003e14. Heterocycles with More than Two Heteroatoms: Higher Azoles (5-Membered) and Higher Azines (6-Membered) 132\u003c\/b\u003e\u003c\/p\u003e \u003cp\u003eHigher Azoles 132\u003c\/p\u003e \u003cp\u003eIntroduction 132\u003c\/p\u003e \u003cp\u003eHigher azoles containing nitrogen as the only ring heteroatom: triazoles, tetrazole and pentazole 132\u003c\/p\u003e \u003cp\u003eBenzotriazole 136\u003c\/p\u003e \u003cp\u003eHigher azoles also containing ring sulfur or oxygen: oxa- and thiadiazoles 137\u003c\/p\u003e \u003cp\u003eHigher azines 139\u003c\/p\u003e \u003cp\u003eExercises 142\u003c\/p\u003e \u003cp\u003e\u003cb\u003e15. Heterocycles with Ring-Junction Nitrogen (Bridgehead Nitrogen) 143\u003c\/b\u003e\u003c\/p\u003e \u003cp\u003eIntroduction 143\u003c\/p\u003e \u003cp\u003eIndolizine 144\u003c\/p\u003e \u003cp\u003eAzaindolizines 144\u003c\/p\u003e \u003cp\u003eSynthesis of indolizines and azaindolizines 146\u003c\/p\u003e \u003cp\u003eQuinoliziniums and quinolizinones 147\u003c\/p\u003e \u003cp\u003eHeteropyrrolizines (pyrrolizines containing additional heteroatoms) 148\u003c\/p\u003e \u003cp\u003eCyclazines 148\u003c\/p\u003e \u003cp\u003eExercises 149\u003c\/p\u003e \u003cp\u003e\u003cb\u003e16. Non-Aromatic Heterocycles 150\u003c\/b\u003e\u003c\/p\u003e \u003cp\u003eIntroduction 150\u003c\/p\u003e \u003cp\u003eThree-membered rings 150\u003c\/p\u003e \u003cp\u003eFour-membered rings 153\u003c\/p\u003e \u003cp\u003eFive- and six-membered rings 153\u003c\/p\u003e \u003cp\u003eRing synthesis 155\u003c\/p\u003e \u003cp\u003e\u003cb\u003e17. Heterocycles in Nature 158\u003c\/b\u003e\u003c\/p\u003e \u003cp\u003eHeterocyclic α-amino acids and related substances 158\u003c\/p\u003e \u003cp\u003eHeterocyclic vitamins – co-enzymes 159\u003c\/p\u003e \u003cp\u003ePorphobilinogen and the ‘Pigments of Life’ 162\u003c\/p\u003e \u003cp\u003eDeoxyribonucleic acid (DNA), the store of genetic information, and ribonucleic acid (RNA), its deliverer 163\u003c\/p\u003e \u003cp\u003eHeterocyclic secondary metabolites 165\u003c\/p\u003e \u003cp\u003e\u003cb\u003e18. Heterocycles in Medicine 167\u003c\/b\u003e\u003c\/p\u003e \u003cp\u003eMedicinal chemistry – how drugs function 167\u003c\/p\u003e \u003cp\u003eDrug discovery 168\u003c\/p\u003e \u003cp\u003eDrug development 169\u003c\/p\u003e \u003cp\u003eThe neurotransmitters 169\u003c\/p\u003e \u003cp\u003eHistamine 170\u003c\/p\u003e \u003cp\u003eAcetylcholine (ACh) 171\u003c\/p\u003e \u003cp\u003eAnticholinesterase agents 172\u003c\/p\u003e \u003cp\u003e5-Hydroxytryptamine (5-HT) (serotonin) 172\u003c\/p\u003e \u003cp\u003eAdrenaline and noradrenaline 173\u003c\/p\u003e \u003cp\u003eOther significant cardiovascular drugs 173\u003c\/p\u003e \u003cp\u003eDrugs acting specifically on the CNS 173\u003c\/p\u003e \u003cp\u003eOther enzyme inhibitors 174\u003c\/p\u003e \u003cp\u003eAnti-infective agents 175\u003c\/p\u003e \u003cp\u003eAntiparasitic drugs 175\u003c\/p\u003e \u003cp\u003eAntibacterial drugs 176\u003c\/p\u003e \u003cp\u003eAntiviral drugs 177\u003c\/p\u003e \u003cp\u003eAnticancer drugs 177\u003c\/p\u003e \u003cp\u003ePhotochemotherapy 178\u003c\/p\u003e \u003cp\u003e\u003cb\u003e19. Applications and Occurrences of Heterocycles in Everyday Life 180\u003c\/b\u003e\u003c\/p\u003e \u003cp\u003eIntroduction 180\u003c\/p\u003e \u003cp\u003eDyes and pigments 180\u003c\/p\u003e \u003cp\u003ePolymers 181\u003c\/p\u003e \u003cp\u003ePesticides 182\u003c\/p\u003e \u003cp\u003eExplosives 184\u003c\/p\u003e \u003cp\u003eFood and drink 186\u003c\/p\u003e \u003cp\u003eHeterocyclic chemistry of cooking 187\u003c\/p\u003e \u003cp\u003eNatural and synthetic food colours 190\u003c\/p\u003e \u003cp\u003eFlavours and fragrances (F\u0026amp;F) 190\u003c\/p\u003e \u003cp\u003eToxins 192\u003c\/p\u003e \u003cp\u003eElectrical and electronic 193\u003c\/p\u003e \u003cp\u003eIndex 195\u003c\/p\u003e \"Joule and Mills have succeeded here in condensing the essence of introductory undergraduate heterocyclic chemistry into a slim volume, presented (as is the way in this series) in an A4 page format and in a very easy-to-grasp style with many structures and reactions. All of the key areas are covered. ...the price and the concise nature of the text make it a feasible purchase and easy read for all those working in the area. I shall certainly be recommending it to my own classes.\" Chemistry World, June 2007  \u003cp\u003e \"The book delivers on its stated purpose to present the key concepts of heterocyclic chemistry to the nonspecialist and will likely find good application in the hands of molecular modelers, pharmacologists and undergraduates.\" Journal of Medicinal Chemistry, 2007, Vol.50, No.4, p6289\u003c\/p\u003e \u003cp\u003e\u003cb\u003eProfessor Emeritus John Joule, Chemistry Department, The University of Manchester, UK\u003c\/b\u003e\u003cbr\u003eProfessor Joule worked for 41 years at the University of Manchester before being appointed Professor Emeritus in 2004. Sabbatical periods were spent at the University of Ibadan, Nigeria, Johns Hopkins Medical School, Department of Pharmacology and Experimental Therapeutics, and the University of Maryland, Baltimore County. He was William Evans Visiting Fellow at Otago University, New Zealand. He has taught many courses on heterocyclic chemistry to industry and academe in the UK and elsewhere. He is currently Associate Editor for \u003ci\u003eTetrahedron Letters\u003c\/i\u003e, Scientific Editor for \u003ci\u003eArkivoc\u003c\/i\u003e, and Co-Editor of the annual \u003ci\u003eProgress in Heterocyclic Chemistry\u003c\/i\u003e. He is co-author with Keith Mills of the leading textbook in the field, \u003ci\u003eHeterocyclic Chemistry\u003c\/i\u003e (Wiley, 5th Edition 2010).\u003c\/p\u003e \u003cp\u003e\u003cb\u003eDr Keith Mills, Independent Consultant, UK\u003c\/b\u003e\u003cbr\u003eDr Mills worked in Medicinal Chemistry and Development Chemistry departments of GlaxoSmithKline for a total of 25 years. Since leaving GSK he has been an independent consultant to small pharmaceutical companies. Dr. Mills has worked in several areas of medicine and many areas of organic chemistry, but with particular emphasis on heterocyclic chemistry and the applications of transition metal-catalysed reactions. With John Joule he is co-author of the leading textbook in the field, \u003ci\u003eHeterocyclic Chemistry\u003c\/i\u003e (Wiley, 5th Edition 2010).\u003c\/p\u003e \u003cp\u003eHeterocyclic chemistry is a central part of organic chemistry and biochemistry, dealing with a particular set of chemical structures; organic compounds with a ring structure containing at least one heteroatom (commonly nitrogen, oxygen or sulfur).\u003c\/p\u003e \u003cp\u003e\u003ci\u003eHeterocyclic Chemistry at a Glance, Second Edition\u003c\/i\u003e provides both an introduction and summary of the main principles and reactions of heterocyclic chemistry, for students studying chemistry and related courses at undergraduate level.\u003c\/p\u003e \u003cp\u003eThis second edition has been much expanded, allowing for a more thorough treatment of key principles and the inclusion of extra examples and illustrations, including heterocycles used in electronics, explosives, polymers, dyestuffs, pigments and that occur in food. All chapters have been revised and updated, including references to books and reviews, and student exercises, with answers on line at \u003ci\u003ehttp:\/\/booksupport.wiley.com\u003c\/i\u003e. New to this edition is the use of colour in schemes and diagrams highlighting parts of products (or intermediates) where a change in structure or bonding has taken place.\u003c\/p\u003e \u003cp\u003eBased on the highly successful and student-friendly \"at a glance\" approach, the material developed in this book has been chosen to help the student grasp the essence of heterocyclic chemistry, ensuring that they can confidently use that knowledge when required. The structure of the book allows for quick assimilation, understanding and recall of key concepts, facts and definitions, providing an invaluable aid to revision for students preparing for examinations.\u003c\/p\u003e \u003cp\u003e\u003cb\u003eReviews for the first edition:\u003c\/b\u003e\u003c\/p\u003e \u003cp\u003e\"This book can be recommended to students looking for a textbook on heterocyclic chemistry. The organization of the material is oriented towards the needs of undergraduate students, but nevertheless the book is comprehensive and will also be of value for more advanced readers.\"\u003cbr\u003e\u003ci\u003e\u003cb\u003e—Heterocycles\u003c\/b\u003e\u003c\/i\u003e\u003c\/p\u003e \"Joule and Mills have succeeded here in condensing the essence of introductory undergraduate heterocyclic chemistry into a slim volume, presented (as is the way in this series) in an A4 page format and in a very easy-to-grasp style with many structures and reactions. All of the key areas are covered.\"\u003cbr\u003e\u003cb\u003e\u003ci\u003e—Chemistry World\u003c\/i\u003e\u003c\/b\u003e","brand":"Wiley","offers":[{"title":"Default Title","offer_id":47989359116517,"sku":"NP9780470971215","price":50.0,"currency_code":"USD","in_stock":false}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/1842\/7735\/files\/9780470971215.jpg?v=1761783806","url":"https:\/\/k12savings.com\/es\/products\/heterocyclic-chemistry-at-a-glance-isbn-9780470971215","provider":"K12savings","version":"1.0","type":"link"}