{"product_id":"handbook-of-radiopharmaceuticals-isbn-9781119500544","title":"Handbook of Radiopharmaceuticals","description":"\u003cp\u003e\u003cb\u003eThe thoroughly updated new edition of the authoritative reference in Radiopharmaceutical Sciences\u003c\/b\u003e\u003c\/p\u003e \u003cp\u003eThe second edition of \u003ci\u003eHandbook of Radiopharmaceuticals\u003c\/i\u003e is a comprehensive review of the field, presenting up-to-date coverage of central topics such as radionuclide production, synthetic methodology, radiopharmaceutical development and regulations, and a wide range of practical applications. A valuable reference work for those new to the Radiopharmaceutical Sciences and experienced professionals alike, this volume explores the latest concepts and issues involving both targeted diagnostic and therapeutic radiopharmaceuticals. Contributions from a team of experts from across sub-disciplines provide readers with an immersive examination of radiochemistry, nuclear medicine, molecular imaging, and more.\u003c\/p\u003e \u003cp\u003eSince the first edition of the \u003ci\u003eHandbook\u003c\/i\u003e was published, Nuclear Medicine and Radiopharmaceutical Sciences have undergone major changes. New radiopharmaceuticals for diagnosis and therapy have been approved by the FDA, the number of clinical PET and SPECT scans have increased significantly, and advances in Artificial Intelligence have dramatically improved research techniques. This fully revised edition reflects the current state of the field and features substantially updated and expanded content. New chapters cover topics including current Good Manufacturing Practice (cGMP), regulatory oversight, novel approaches to quality control—ensuring that readers are informed of the exciting developments of recent years. This important resource:\u003c\/p\u003e \u003cul\u003e \u003cli\u003eFeatures extensive new and revised content throughout\u003c\/li\u003e \u003cli\u003eCovers key areas of application for diagnosis and therapy in oncology, neurology, and cardiology\u003c\/li\u003e \u003cli\u003eEmphasizes the multidisciplinary nature of Radiopharmaceutical Sciences\u003c\/li\u003e \u003cli\u003eDiscusses how drug companies are using modern radiopharmaceutical imaging techniques to support drug discovery\u003c\/li\u003e \u003cli\u003eExamines current and emerging applications of Positron Emission Tomography (PET) and Single Photon Emission Computed Tomography (SPECT)\u003c\/li\u003e \u003c\/ul\u003e \u003cp\u003eEdited by recognized experts in radiochemistry and PET imaging, \u003ci\u003eHandbook of Radiopharmaceuticals: Radiochemistry and Applications\u003c\/i\u003e, 2nd Edition is an indispensable reference for post-doctoral fellows, research scientists, and professionals in the pharmaceutical industry, and for academics, graduate students, and newcomers in the field of radiopharmaceuticals.\u003c\/p\u003eSorgfältig aktualisierte Neuauflage dieses wegweisenden Referenzwerk der radiopharmazeutischen Wissenschaften\u003cbr\u003e Die 2. Auflage des Handbook of Radiopharmaceuticals wirft einen umfassenden analytischen Blick auf das Fachgebiet und bietet aktuelle Informationen zu zentralen Themen, u. a. die Herstellung von Radionukliden, synthetische Methoden, Entwicklungen in der Radiopharmazie, Regelwerke, und zu einer Fülle praktischer Anwendungen. Als wertvolles Nachschlagewerk für Einsteiger und erfahrene Praktiker untersucht diese Publikation die neuesten Konzepte und Fragestellungen unter Berücksichtigung des gezielten Einsatzes diagnostischer und therapeutischer Radiopharmazeutika. Die Beiträge stammen von Experten verschiedenster Unterdisziplinen und lassen den Leser eintauchen in die Radiochemie, Nuklearmedizin, molekulare Bildgebung u.v.m.\u003cbr\u003e \u003cbr\u003e Die Nuklearmedizin und radiopharmazeutischen Wissenschaften haben sich seit Veröffentlichung der 1. Auflage stark verändert. Neue Radiopharmazeutika für Diagnostik und Therapie wurden von der FDA zugelassen, klinische PET- und SPECT-Scans haben drastisch zugenommen und Fortschritte im Bereich Künstliche Intelligenz haben zu signifikant verbesserten Forschungsverfahren geführt. Diese vollständig überarbeitete Auflage stellt den derzeitigen Erkenntnisstand des Fachgebiets vor, ergänzt um aktualisierte und neue Inhalte. Neue Kapitel beschäftigen sich mit heutigen Good Manufacturing Practice, regulatorischen Entwicklungen und neuen Ansätzen bei der Qualitätskontrolle. Damit wird sichergestellt, dass die Leserschaft über die aufregenden Entwicklungen der letzten Jahre rundum im Bilde ist. Dieses wichtige Referenzwerk\u003cbr\u003e - bietet durchgängig neue und überarbeitete Inhalte.\u003cbr\u003e - deckt zentrale Anwendungsbereiche in der Diagnostik und Therapie ab, für die Onkologie, Neurologie und Kardiologie.\u003cbr\u003e - unterstreicht die multidisziplinäre Ausrichtung der radiopharmazeutischen Wissenschaften.\u003cbr\u003e - zeigt, wie Pharmaunternehmen mit modernen Bildgebungsverfahren der Radiopharmazie neue Medikamente entwickeln.\u003cbr\u003e - untersucht heutige und neue Anwendungen der Positronen-Emissions-Tomographie (PET) und Single-Photonen-Emissions-Computertomographie (SPECT).\u003cbr\u003e \u003cbr\u003e \u003cbr\u003e Die Herausgeber sind anerkannte Experten der Fachrichtungen Radiochemie und PET-Bildgebung. Die 2. Auflage des Handbook of Radiopharmaceuticals: Radiochemistry and Applications ist ein Muss für Postdoktoranden, Forscher und Fachexperten in der Pharmazeutischen Industrie und richtet sich ebenso an die akademische Forschung und Lehre, an Graduierte und Einsteiger in das Fachgebiet der Radiopharmazeutika.\u003cbr\u003e \u003cp\u003eForeword\u003c\/p\u003e \u003cp\u003ePreface\u003c\/p\u003e \u003cp\u003eList of Contributors\u003c\/p\u003e \u003cp\u003eAbout the Editors\u003c\/p\u003e \u003cp\u003eAbbreviations\u003c\/p\u003e \u003cp\u003ePART I: INTRODUCTION TO RADIOPHARMACEUTICALS\u003c\/p\u003e \u003cp\u003e1. Targeted Diagnostic Radiopharmaceuticals: Design Options for Small Molecule Radiotracers\u003c\/p\u003e \u003cp\u003eMichael R. Kilbourn\u003c\/p\u003e \u003cp\u003e2. Concepts and Issues for Therapeutic Radiopharmaceuticals\u003c\/p\u003e \u003cp\u003eAlexandra R. Sowa Dumond and Peter J. H. Scott\u003c\/p\u003e \u003cp\u003ePART II: PRODUCTION OF RADIONUCLIDES\u003c\/p\u003e \u003cp\u003e3. Production of Short Half-life PET Radionuclides\u003c\/p\u003e \u003cp\u003eMichael R. Kilbourn, Melissa E. Rodnick and Mara Clark\u003c\/p\u003e \u003cp\u003e4. Production of Radionuclides used in SPECT\u003c\/p\u003e \u003cp\u003eSalma Jivan and Thomas J. Ruth\u003c\/p\u003e \u003cp\u003e5. Production of Therapeutic Radionuclides\u003c\/p\u003e \u003cp\u003eC. Shaun Loveless and Suzanne E. Lapi\u003c\/p\u003e \u003cp\u003ePART III: SYNTHETIC METHODS FOR RADIOPHARMACEUTICALS\u003c\/p\u003e \u003cp\u003e6. Synthesis of 13N- and 15O-labeled Radiopharmaceuticals\u003c\/p\u003e \u003cp\u003eKrishna R. Pulagam, Vanessa Gómez-Vallejo, Fernando López-Gallego, Luka Rejc and Jordi Llop\u003c\/p\u003e \u003cp\u003e7. Radiochemistry with Carbon-11\u003c\/p\u003e \u003cp\u003eStephen Thompson, Steven Kealey, Selena M. Sephton and Franklin I. Aigbirhio\u003c\/p\u003e \u003cp\u003e8. Fluorine-18 Radiochemistry\u003c\/p\u003e \u003cp\u003eAllen F. Brooks, Katarina J. Makaravage, Jay Wright, Melanie S. Sanford and Peter J. H. Scott\u003c\/p\u003e \u003cp\u003e9. Synthesis of 68Ga-labeled Radiopharmaceuticals\u003c\/p\u003e \u003cp\u003eBenjamin P. Burke and Stephen J. Archibald \u003c\/p\u003e \u003cp\u003e10. Cu-Mediated Radiohalogenation of Organoboranes\u003c\/p\u003e \u003cp\u003eSean W. Reilly and Robert H. Mach\u003c\/p\u003e \u003cp\u003e11. The radiochemistry of zirconium\u003c\/p\u003e \u003cp\u003eJason P. Holland\u003c\/p\u003e \u003cp\u003e12. 99mTc Radiopharmaceutical Chemistry\u003c\/p\u003e \u003cp\u003eDionysia Papagiannopoulou\u003c\/p\u003e \u003cp\u003ePART IV: PRACTICAL ASPECTS OF RADIOPHARMACEUTICAL PRODUCTION AND USE\u003c\/p\u003e \u003cp\u003e13. Automated Synthesis Modules for PET Radiochemistry\u003c\/p\u003e \u003cp\u003eLaura Bruton and Peter J. H. Scott\u003c\/p\u003e \u003cp\u003e14. Automation of PET Radiopharmaceutical Quality Control\u003c\/p\u003e \u003cp\u003eArkadij Elizarov\u003c\/p\u003e \u003cp\u003e15. Moving PET Drugs from the Lab to the Patient in USA\u003c\/p\u003e \u003cp\u003eDavid W. Dick\u003c\/p\u003e \u003cp\u003e16. Moving from the Lab to the Patient in Asia\u003c\/p\u003e \u003cp\u003eDae Yoon Chi\u003c\/p\u003e \u003cp\u003e17.      Moving a radiotracer form bench to bedside in Europe\u003c\/p\u003e \u003cp\u003eKoen Vermeulen, Alfons Verbruggen, Guy Bormans and Frederik Cleeren\u003c\/p\u003e \u003cp\u003ePART V: MAJOR APPLICATIONS OF RADIOPHARMACEUTICALS\u003c\/p\u003e \u003cp\u003e18. Radiopharmaceuticals in Oncology\u003c\/p\u003e \u003cp\u003eJeroen A.C.M. Goos, Outi Keinänen, Brian M. Zeglis and Jason S. Lewis\u003c\/p\u003e \u003cp\u003e19. Neurological applications of Radiopharmaceuticals\u003c\/p\u003e \u003cp\u003eMehdi Djekidel and Nicolaas I. Bohnen\u003c\/p\u003e \u003cp\u003e20. Cardiac Applications of Radiopharmaceuticals\u003c\/p\u003e \u003cp\u003eJohn P. Bois and Robert J. Gropler\u003c\/p\u003e \u003cp\u003e21. Radiopharmaceuticals in Pediatric Nuclear Medicine\u003c\/p\u003e \u003cp\u003eScott E. Snyder, Elizabeth R. Butch and Barry L. Shulkin\u003c\/p\u003e \u003cp\u003e22. PET Imaging in Drug Discovery and Development\u003c\/p\u003e \u003cp\u003eDavid J. Donnelly\u003c\/p\u003e \u003cp\u003eINDEX\u003c\/p\u003e  \u003cp\u003e\u003cb\u003eEdited by\u003c\/b\u003e \u003c\/p\u003e\u003cp\u003e\u003cb\u003eMichael R. Kilbourn, PhD,\u003c\/b\u003e is Professor Emeritus, Radiology, at the University of Michigan. He retired after 25 years of directing and expanding the University's PET Cyclotron and Radiochemistry program. Professor Kilbourn is the author of over 200 peer-reviewed scientific papers and 31 book chapters, and is the 2009 recipient of the Paul C. Aebersold Award for Outstanding Achievements in Basic Science Applied to Nuclear Medicine. \u003c\/p\u003e\u003cp\u003e\u003cb\u003ePeter J. H. Scott, PhD,\u003c\/b\u003e is Associate Professor, Radiology, and Director of the PET Center at the University of Michigan. His research focuses on developing new methods for radiolabeling bioactive molecules and the design and synthesis of new radiotracers for PET imaging. Professor Scott has published over 100 papers, 170 abstracts, and 30 book chapters, edited 4 books, and is listed as an inventor on multiple patents. In 2019 he received a Distinguished Investigator Award from the Academy for Radiology \u0026amp; Biomedical Imaging Research.  \u003c\/p\u003e\u003cp\u003e\u003cb\u003eThe thoroughly updated new edition of the authoritative reference in Radiopharmaceutical Sciences\u003c\/b\u003e\u003c\/p\u003e \u003cp\u003eThe second edition of \u003ci\u003eHandbook of Radiopharmaceuticals\u003c\/i\u003e is a comprehensive review of the field, presenting up-to-date coverage of central topics such as radionuclide production, synthetic methodology, radiopharmaceutical development and regulations, and a wide range of practical applications. A valuable reference work for those new to the Radiopharmaceutical Sciences and experienced professionals alike, this volume explores the latest concepts and issues involving both targeted diagnostic and therapeutic radiopharmaceuticals. Contributions from a team of experts from across sub-disciplines provide readers with an immersive examination of radiochemistry, nuclear medicine, molecular imaging, and more.\u003c\/p\u003e \u003cp\u003eSince the first edition of the \u003ci\u003eHandbook\u003c\/i\u003e was published, Nuclear Medicine and Radiopharmaceutical Sciences have undergone major changes. New radiopharmaceuticals for diagnosis and therapy have been approved by the FDA, the number of clinical PET and SPECT scans have increased significantly, and advances in Artificial Intelligence have dramatically improved research techniques. This fully revised edition reflects the current state of the field and features substantially updated and expanded content. New chapters cover topics including current Good Manufacturing Practice (cGMP), regulatory oversight, novel approaches to quality control—ensuring that readers are informed of the exciting developments of recent years. This important resource:\u003c\/p\u003e \u003cul\u003e \u003cli\u003eFeatures extensive new and revised content throughout\u003c\/li\u003e \u003cli\u003eCovers key areas of application for diagnosis and therapy in oncology, neurology, and cardiology\u003c\/li\u003e \u003cli\u003eEmphasizes the multidisciplinary nature of Radiopharmaceutical Sciences\u003c\/li\u003e \u003cli\u003eDiscusses how drug companies are using modern radiopharmaceutical imaging techniques to support drug discovery\u003c\/li\u003e \u003cli\u003eExamines current and emerging applications of Positron Emission Tomography (PET) and Single Photon Emission Computed Tomography (SPECT)\u003c\/li\u003e \u003c\/ul\u003e \u003cp\u003eEdited by recognized experts in radiochemistry and PET imaging, \u003ci\u003eHandbook of Radiopharmaceuticals: Radiochemistry and Applications, 2nd Edition\u003c\/i\u003e is an indispensable reference for post-doctoral fellows, research scientists, and professionals in the pharmaceutical industry, and for academics, graduate students, and newcomers in the field of radiopharmaceuticals.\u003c\/p\u003e","brand":"Wiley","offers":[{"title":"Default Title","offer_id":47989340864741,"sku":"NP9781119500544","price":355.95,"currency_code":"USD","in_stock":false}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/1842\/7735\/files\/9781119500544.jpg?v=1761783734","url":"https:\/\/k12savings.com\/es\/products\/handbook-of-radiopharmaceuticals-isbn-9781119500544","provider":"K12savings","version":"1.0","type":"link"}