{"product_id":"gram-positive-pathogens-isbn-9781683670124","title":"Gram-Positive Pathogens","description":"\u003cp\u003eGram-positive bacteria, lacking an outer membrane and related secretory systems and having a thick peptidoglycan, have developed novel approaches to pathogenesis by acquiring (among others) a unique family of surface proteins, toxins, enzymes, and prophages. For the new edition, the editors have enhanced this fully researched compendium of Gram-positive bacterial pathogens by including new data generated using genomic sequencing as well as the latest knowledge on Gram-positive structure and mechanisms of antibiotic resistance and theories on the mechanisms of Gram-positive bacterial pathogenicity. This edition emphasizes streptococci, staphylococci, listeria, and spore-forming pathogens, with chapters written by many of the leading researchers in these areas. The chapters systematically dissect these organisms biologically, genetically, and immunologically, in an attempt to understand the strategies used by these bacteria to cause human disease.\u003cbr\u003e\u003cbr\u003e\u003c\/p\u003e \u003cp\u003e“This textbook comprises a superb collection of scientific knowledge making it a must-read for any graduate student, medical doctor, or investigator studying these gram-positive bacteria and inspiring future imaginations of biological knowledge.” - William R. Jacobs, Jr., PhD, Professor Microbiology \u0026amp; Immunology, Albert Einstein College of Medicine\u003c\/p\u003e \u003cp\u003e \u003c\/p\u003e \u003cp\u003eDedication\u003c\/p\u003e \u003cp\u003eContributors\u003c\/p\u003e \u003cp\u003ePreface\u003c\/p\u003e About the Editors \u003cp\u003e\u003cb\u003eSection 1: The Gram-Positive Cell Wall\u003cbr\u003e\u003c\/b\u003e\u003ci\u003eVincent A. Fischetti\u003c\/i\u003e\u003c\/p\u003e \u003cp\u003e1 The Gram-Positive Cell Wall\u003cbr\u003e \u003ci\u003eManfred Rohde\u003cbr\u003e \u003c\/i\u003e\u003cbr\u003e 2 Surface Proteins on Gram-Positive Bacteria\u003cbr\u003e \u003ci\u003eVincent A. Fischetti\u003cbr\u003e \u003c\/i\u003e\u003cbr\u003e \u003cb\u003eSection 2: The Streptococcus\u003cbr\u003e\u003c\/b\u003e\u003ci\u003eVincent A. Fischetti and Joseph J. Ferretti \u003c\/i\u003e\u003c\/p\u003e \u003cp\u003e\u003cb\u003eGroup A Streptococci\u003cbr\u003e \u003cbr\u003e \u003c\/b\u003e3 Intracellular Invasion by Streptococcus pyogenes: Invasins, Host Receptors, and Relevance to Human Disease\u003cbr\u003e \u003ci\u003eBeinan Wang and P. Patrick Cleary\u003cbr\u003e \u003c\/i\u003e\u003cbr\u003e 4 Capsular Polysaccharide of Group A Streptococci \u003cbr\u003e \u003ci\u003eMichael Wessels\u003cbr\u003e \u003c\/i\u003e\u003cbr\u003e 5 Toxins and Superantigens of Group A Streptococci\u003cbr\u003e \u003ci\u003eBlake A. Shannon, John K. McCormick, and Patrick M. Schlievert\u003cbr\u003e \u003c\/i\u003e\u003cbr\u003e 6 Genetics of Group A Streptococci\u003cbr\u003e \u003ci\u003eKyu Hong Cho, Gary Port, and Michael Caparon\u003cbr\u003e \u003c\/i\u003e\u003cbr\u003e 7 Molecular Mimicry, Autoimmunity, and Infection: The Cross-Reactive Antigens of Group A Streptococci and Their Sequelae\u003cbr\u003e \u003ci\u003eMadeline W. Cunningham\u003cbr\u003e \u003cbr\u003e \u003c\/i\u003e8 Extracellular Matrix Interactions with Gram-Positive Pathogens\u003cbr\u003e \u003ci\u003eSven Hammerschmidt, Manfred Rohde, and Klaus T. Preissner\u003cbr\u003e \u003c\/i\u003e\u003cbr\u003e 9 Streptococcus-Mediated Host Cell Signaling\u003cbr\u003e \u003ci\u003eVijay Pancholi\u003cbr\u003e \u003c\/i\u003e\u003cbr\u003e 10 Vaccine Approaches to Protect Against Group A Streptococcal Pharyngitis\u003cbr\u003e \u003ci\u003eVincent Fischetti\u003cbr\u003e \u003c\/i\u003e\u003cbr\u003e 11 The Bacteriophages of Group A Streptococci\u003cbr\u003e \u003ci\u003eW. Michael McShan\u003cbr\u003e \u003cbr\u003e \u003c\/i\u003e12 Molecular Epidemiology, Ecology, and Evolution of Group A Streptococci\u003cbr\u003e \u003ci\u003eDebra E. Bessen, Pierre R. Smeesters, and Bernard W. Beall\u003cbr\u003e \u003c\/i\u003e\u003cbr\u003e \u003cb\u003eGroup B Streptococci\u003cbr\u003e \u003c\/b\u003e\u003cbr\u003e 13 Surface Structures of Group B Streptococci Important to Human Immunity\u003cbr\u003e \u003ci\u003eLawrence Paoletti and Dennis Kasper\u003cbr\u003e \u003c\/i\u003e\u003cbr\u003e 14 Epidemiology of Group B Streptococcal Infections\u003cbr\u003e \u003ci\u003eVanessa N. Raabe and Andi L. Shane\u003cbr\u003e \u003c\/i\u003e\u003cbr\u003e \u003cb\u003eGroup C and G Streptococci\u003cbr\u003e \u003c\/b\u003e\u003cbr\u003e 15 Genetics and Pathogenicity Factors of Group C and G Streptococci\u003cbr\u003e \u003ci\u003eHorst Malke\u003cbr\u003e \u003c\/i\u003e\u003cbr\u003e 16 Pathogenicity Factors in Group C and G Streptococci\u003cbr\u003e \u003ci\u003eClaire E. Turner, Laura Bubba, and Androulla Efstratiou\u003cbr\u003e \u003c\/i\u003e\u003cbr\u003e 17 Infections Caused by Group C and G Streptococcus (Streptococcus dysgalactiae subsp. equisimilis and Others): Epidemiological and Clinical Aspects\u003cbr\u003e\u003ci\u003eGio Baracco\u003c\/i\u003e\u003c\/p\u003e \u003cp\u003e\u003cb\u003eStreptococcus pneumoniae\u003cbr\u003e \u003c\/b\u003e\u003cbr\u003e 18 The Cell Wall of Streptococcus pneumoniae\u003cbr\u003e \u003ci\u003eWaldemar Vollmer, Orietta Massidda, and Alexander Tomasz\u003cbr\u003e \u003c\/i\u003e\u003cbr\u003e 19 Streptococcus pneumoniae Capsular Polysaccharide\u003cbr\u003e \u003ci\u003eJames Paton and Judy Morona\u003cbr\u003e \u003c\/i\u003e\u003cbr\u003e 20  Streptococcus pneumoniae: Invasion and Inflammation\u003cbr\u003e \u003ci\u003eAllister J. Loughran, Carlos J. Orihuela, and Elaine I. Tuomanen\u003cbr\u003e \u003c\/i\u003e\u003cbr\u003e 21 Phase Variation of Streptococcus pneumoniae\u003cbr\u003e \u003ci\u003eJing Li and Jing-Ren Zhang \u003cbr\u003e \u003c\/i\u003e\u003cbr\u003e 22 Genetics of Streptococcus pneumoniae\u003cbr\u003e \u003ci\u003eFrancesco Santoro, Francesco Iannelli, and Gianni Pozzi\u003cbr\u003e \u003c\/i\u003e\u003cbr\u003e 23 Pneumococcal Vaccines\u003cbr\u003e \u003ci\u003eDavid E. Briles, James C. Paton, Reshmi Mukerji, Edward Swiatlo, and Marilyn J. Crain\u003cbr\u003e \u003c\/i\u003e\u003cbr\u003e \u003cb\u003eEnterococci\u003cbr\u003e \u003c\/b\u003e\u003cbr\u003e 24 Pathogenicity of Enterococci\u003cbr\u003e \u003ci\u003eElizabeth M. Selleck, Daria Van Tyne, and Michael S. Gilmore\u003cbr\u003e \u003c\/i\u003e\u003cbr\u003e 25 Enterococcal Genetics\u003cbr\u003e \u003ci\u003eKeith E. Weaver\u003cbr\u003e \u003c\/i\u003e\u003cbr\u003e \u003cb\u003eOral Streptococci\u003cbr\u003e \u003c\/b\u003e\u003cbr\u003e 26 Biology of Oral Streptococci\u003cbr\u003e \u003ci\u003eJ. Abranches, L. Zeng, J. K. Kajfasz, S. R. Palmer, B. Chakraborty, Z. T. Wen, V. P. Richards, L. J. Brady, and J. A. Lemos\u003cbr\u003e \u003c\/i\u003e\u003cbr\u003e 27 The Biology of Streptococcus mutans\u003cbr\u003e\u003ci\u003eJ. A. Lemos\u003c\/i\u003e\u003c\/p\u003e \u003cp\u003e28 Genetics of Sanguinis-Group Streptococci in Health and Disease\u003cbr\u003e \u003ci\u003eAngela Nobbs and Jens Kreth\u003cbr\u003e \u003c\/i\u003e\u003cbr\u003e \u003cb\u003eLactococci\u003cbr\u003e \u003c\/b\u003e\u003cbr\u003e 29 Genetics of Lactococci\u003cbr\u003e \u003ci\u003ePhilippe Gaudu, Yuji Yamamoto, Peter Ruhdal Jensen, Karin Hammer, Delphine Lechardeur, and Alexandra Gruss\u003cbr\u003e \u003c\/i\u003e\u003cbr\u003e \u003cb\u003eSection 3: The Staphylococcus\u003cbr\u003e\u003c\/b\u003e\u003ci\u003eRichard P. Novick\u003cbr\u003e\u003cbr\u003e\u003c\/i\u003e30 The Evolving Genome\u003cbr\u003e\u003ci\u003eJodi Lindsay\u003c\/i\u003e\u003c\/p\u003e \u003cp\u003e31 Plasmids and Transposable and Integrative Elements\u003cbr\u003e \u003ci\u003eNeville Firth, Slade O. Jensen, Stephen M. Kwong, Ronald A. Skurray, and Joshua P. Ramsay\u003cbr\u003e \u003c\/i\u003e\u003cbr\u003e 32 Temperate Phages of Staphylococcus aureus\u003cbr\u003e \u003ci\u003eHanne Ingmer, David Gerlach, and Christine Wolz\u003cbr\u003e \u003c\/i\u003e\u003cbr\u003e 33 Pathogenicity Islands and Their Role in Staphylococcal Biology\u003cbr\u003e \u003ci\u003eRichard Novick\u003cbr\u003e \u003c\/i\u003e\u003cbr\u003e 34 Respiration and Small Colony Variants of Staphylococcus aureus\u003cbr\u003e \u003ci\u003eRichard Proctor\u003cbr\u003e \u003c\/i\u003e\u003cbr\u003e 35 Noncoding RNA\u003cbr\u003e \u003ci\u003eEmma Desgranges, Stefano Marzi, Karen Moreau, Pascale Romby, and Isabelle Caldelari\u003cbr\u003e \u003c\/i\u003e\u003cbr\u003e 36 The Staphylococcal Cell Wall\u003cbr\u003e \u003ci\u003eRita Sobral and Alexander Tomasz\u003cbr\u003e \u003c\/i\u003e\u003cbr\u003e 37 Staphylococcal Protein Secretion and Envelope Assembly\u003cbr\u003e \u003ci\u003eOlaf Schneewind and Dominique M. Missiakas\u003cbr\u003e \u003c\/i\u003e\u003cbr\u003e 38 Surface Proteins Required for Adhesion and Invasion\u003cbr\u003e \u003ci\u003eTimothy J. Foster\u003cbr\u003e \u003c\/i\u003e\u003cbr\u003e 39 Immune Evasion by Staphylococcus aureus\u003cbr\u003e \u003ci\u003eNienke W. M. de Jong, Kok P. M. van Kessel, and Jos A. G. van Strijp\u003cbr\u003e \u003c\/i\u003e\u003cbr\u003e 40 Staphylococcus aureus Secreted Toxins and Extracellular Enzymes\u003cbr\u003e \u003ci\u003eVictor J. Torres\u003cbr\u003e \u003c\/i\u003e\u003cbr\u003e 41 Regulation of Staphylococcus aureus Virulence\u003cbr\u003e \u003ci\u003eChristian Jenul and Alexander R. Horswill\u003cbr\u003e \u003c\/i\u003e\u003cbr\u003e 42 Virulence and Metabolism\u003cbr\u003e \u003ci\u003eAnthony R. Richardson\u003cbr\u003e \u003c\/i\u003e\u003cbr\u003e 43 Staphylococcal Biofilms\u003cbr\u003e \u003ci\u003eMichael Otto\u003cbr\u003e \u003c\/i\u003e\u003cbr\u003e 44 Fulminant Staphylococcal Infections\u003cbr\u003e \u003ci\u003eYves Gillet, Thomas Henry, and Françios Vandenesch\u003cbr\u003e \u003c\/i\u003e\u003cbr\u003e 45 Staphylococcus aureus Colonization of the Human Nose and Interaction with Other Microbiome Members\u003cbr\u003e \u003ci\u003eClaudia Laux, Andreas Peschel, and Bernhard Krismer\u003cbr\u003e \u003cbr\u003e \u003c\/i\u003e46 Staphylococcus aureus in Animals\u003cbr\u003e \u003ci\u003eAndreas F. Haag, J. Ross Fitzgerald, and José R. Penadés\u003cbr\u003e \u003c\/i\u003e\u003cbr\u003e 47 Antibiotic Resistance and the MRSA Problem\u003cbr\u003e \u003ci\u003eMartin Vestergaard, Dorte Frees, and Hanne Ingmer\u003cbr\u003e \u003c\/i\u003e\u003cbr\u003e 48 Immunity to Staphylococcus aureus: Implications for Vaccine Development\u003cbr\u003e \u003ci\u003eRichard A. Proctor\u003cbr\u003e \u003c\/i\u003e\u003cbr\u003e 49 Nonconventional Therapeutics Against Staphylococcus aureus\u003cbr\u003e \u003ci\u003eEric Skaar\u003cbr\u003e \u003cbr\u003e \u003c\/i\u003e\u003cb\u003eSection 4: The Listeriae\u003cbr\u003e\u003c\/b\u003e\u003ci\u003eDaniel A. Portnoy\u003c\/i\u003e\u003c\/p\u003e \u003cp\u003e50 Epidemiology and Clinical Manifestations of Listeria monocytogenes Infection\u003cbr\u003e \u003ci\u003eWalter F. Schlech III\u003cbr\u003e \u003c\/i\u003e\u003cbr\u003e 51 Innate and Adaptive Immune Responses during Listeria monocytogenes Infection\u003cbr\u003e \u003ci\u003eSarah E.F. D'Orazio\u003cbr\u003e \u003c\/i\u003e\u003cbr\u003e 52 Regulation of Listeria monocytogenes Virulence\u003cbr\u003e \u003ci\u003eJörgen Johannson and Nancy E. Freitag\u003cbr\u003e \u003c\/i\u003e\u003cbr\u003e 53 The Cell Biology of Invasion and Intracellular Growth by Listeria monocytogenes\u003cbr\u003e \u003ci\u003eJavier Pizarro-Cerdá and Pascale Cossart\u003cbr\u003e \u003c\/i\u003e\u003cbr\u003e 54 Metabolism of the Gram-Positive Bacterial Pathogen Listeria monocytogenes\u003cbr\u003e \u003ci\u003eJohn-Demian Sauer, Anat A. Herskovits, and Mary X. D. O’Riordan\u003cbr\u003e \u003c\/i\u003e\u003cbr\u003e \u003cb\u003eSection 5: Spore-Forming Pathogens\u003cbr\u003e\u003c\/b\u003e\u003ci\u003eJulian I. Rood\u003c\/i\u003e\u003c\/p\u003e \u003cp\u003e55 The Bacillus cereus Group: Bacillus Species with Pathogenic Potential\u003cbr\u003e \u003ci\u003eMonika Ehling-Sculz, Theresa M. Koehler, and Didier Lereclus\u003cbr\u003e \u003c\/i\u003e\u003cbr\u003e 56 Sporulation and Germination in Clostridial Pathogens\u003cbr\u003e \u003ci\u003eAimee Shen, Adrianne N. Edwards, Mahfuzur R. Sarker, and Daniel Paredes-Sabja\u003cbr\u003e \u003c\/i\u003e\u003cbr\u003e 57 Clostridial Genetics: Genetic Manipulation of the Pathogenic Clostridia\u003cbr\u003e \u003ci\u003eSarah A. Kuehne, Julian I. Rood, and Dena Lyras\u003cbr\u003e \u003c\/i\u003e\u003cbr\u003e 58 Genomics of the Pathogenic Clostridia\u003cbr\u003e \u003ci\u003eRobert J. Moore and Jake A. Lacey\u003cbr\u003e \u003c\/i\u003e\u003cbr\u003e 59 Virulence Plasmids of the Pathogenic Clostridia\u003cbr\u003e \u003ci\u003eSarah A. Revitt-Mills, Callum J. Vidor, Thomas D. Watts, Dena Lyras, Julian I. Rood, and Vicki Adams\u003cbr\u003e \u003c\/i\u003e\u003cbr\u003e 60 Enterotoxic Clostridia: Clostridium perfringens Enteric Diseases\u003cbr\u003e \u003ci\u003eArchana Shrestha, Francisco A. Uzal, and Bruce A. McClane\u003cbr\u003e \u003c\/i\u003e\u003cbr\u003e 61 Enterotoxic Clostridia: Clostridioides difficile Infections\u003cbr\u003e \u003ci\u003eS. Mileto, A. Das, and Dena Lyras\u003cbr\u003e \u003c\/i\u003e\u003cbr\u003e 62 Histotoxic Clostridial Infections\u003cbr\u003e \u003ci\u003eMashahiro Nagahama, Masaya Takehara, and Julian I. Rood\u003cbr\u003e \u003c\/i\u003e\u003cbr\u003e 63 Neurotoxigenic Clostridia\u003cbr\u003e \u003ci\u003eEric A. Johnson\u003cbr\u003e\u003c\/i\u003e\u003cb\u003e\u003cbr\u003eSection 6: Mycobacteria and Corynebacteria\u003cbr\u003e\u003c\/b\u003e\u003ci\u003eMiriam Braunstein\u003c\/i\u003e\u003c\/p\u003e \u003cp\u003e64 Mycobacteriophages\u003cbr\u003e \u003ci\u003eGraham F. Hatfull\u003cbr\u003e \u003c\/i\u003e\u003cbr\u003e 65 Immunology of Mycobacterium tuberculosis Infections\u003cbr\u003e \u003ci\u003eJonathan Kevin Sia and Jyothi Rengarajan\u003cbr\u003e \u003c\/i\u003e\u003cbr\u003e 66 Unraveling the Structure of the Mycobacterial Envelope\u003cbr\u003e\u003ci\u003eMamadou Daffé and Hedia Marrakchi\u003c\/i\u003e\u003c\/p\u003e \u003cp\u003e67 The Dream of a Mycobacterium\u003cbr\u003e \u003ci\u003eCatherine Baranowski, E. Hesper Rego, and Eric J. Rubin\u003cbr\u003e \u003cbr\u003e \u003c\/i\u003e68 Mycobacterium tuberculosis Metabolism\u003cbr\u003e\u003ci\u003eGabriel T. Mashabela1, Timothy J. de Wet, and Digby F. Warner \u003c\/i\u003e\u003c\/p\u003e \u003cp\u003e69 Protein Export Into and Across the Atypical Diderm Cell Envelope of Mycobacteria\u003cbr\u003e \u003ci\u003eVincent J.C. van Winden, Edith N.G. Houben, and Miriam Braunstein\u003cbr\u003e \u003c\/i\u003e\u003cbr\u003e 70 Corynebacterium diphtheriae: Iron-Mediated Activation of dtxR and Regulation of Diphtheria Toxin Expression\u003cbr\u003e \u003ci\u003eSadiya Parveen, William R. Bishai, and John R. Murphy\u003cbr\u003e \u003c\/i\u003e\u003cbr\u003e Index\u003c\/p\u003e \u003cp\u003e“This textbook comprises a superb collection of scientific knowledge making it a must-read for any graduate student, medical doctor, or investigator studying these gram-positive bacteria and inspiring future imaginations of biological knowledge.”\u003cbr\u003e\u003cbr\u003e-  William R. Jacobs, Jr., PhD\u003cbr\u003eProfessor Microbiology \u0026amp; Immunology, Albert Einstein College of Medicine\u003c\/p\u003e \u003cp\u003e \u003c\/p\u003e  \u003cp\u003e\u003cb\u003eGram-Positive Pathogens\u003c\/b\u003e \u003c\/p\u003e\u003cp\u003eThird Edition  \u003c\/p\u003e\u003cp\u003eGram-positive bacteria, lacking an outer membrane and related secretory systems and having a thick peptidoglycan, have developed novel approaches to pathogenesis by acquiring (among others) a unique family of surface proteins, toxins, enzymes, and prophages. For the new edition, the editors have enhanced this fully researched compendium of Gram-positive bacterial pathogens by including new data generated using genomic sequencing as well as the latest knowledge on Gram-positive structure and mechanisms of antibiotic resistance and theories on the mechanisms of Gram-positive bacterial pathogenicity. This edition emphasizes streptococci, staphylococci, listeria, and spore-forming pathogens, with chapters written by many of the leading researchers in these areas. The chapters systematically dissect these organisms biologically, genetically, and immunologically, in an attempt to understand the strategies used by these bacteria to cause human disease.\u003c\/p\u003e","brand":"ASM Press","offers":[{"title":"Default Title","offer_id":47989306523877,"sku":"NP9781683670124","price":185.95,"currency_code":"USD","in_stock":false}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/1842\/7735\/files\/9781683670124.jpg?v=1761783602","url":"https:\/\/k12savings.com\/es\/products\/gram-positive-pathogens-isbn-9781683670124","provider":"K12savings","version":"1.0","type":"link"}