{"product_id":"genomic-and-epigenomic-biomarkers-of-toxicology-and-disease-isbn-9781119807674","title":"Genomic and Epigenomic Biomarkers of Toxicology and Disease","description":"\u003cb\u003eGenomic and Epigenomic Biomarkers of Toxicology and Disease\u003c\/b\u003e \u003cp\u003e\u003cb\u003eThe latest developments in biomarker research applicable to toxicology and medicine\u003c\/b\u003e \u003c\/p\u003e\u003cp\u003eResearch on genomic and epigenomic biomarkers is developing rapidly with cutting-edge studies scattered throughout the academic literature, making the status of ongoing scientific activity in this area difficult to ascertain.  \u003c\/p\u003e\u003cp\u003e\u003ci\u003eGenomic and Epigenomic Biomarkers of Toxicology and Disease: Clinical and Therapeutic Actions\u003c\/i\u003e delivers a comprehensive and authoritative compilation of up-to-date developments in the application of genomic and epigenomic biomarkers to toxicology, disease prevention, cancer detection, therapeutics, gene therapy, and other areas. With contributions from a collection of internationally recognized investigators, this edited volume offers unique insights into current trends and future directions of research in the discussed areas.  \u003c\/p\u003e\u003cp\u003e Combining state-of-the-art information on genomic and epigenomic biomarkers from a range of specialists from around the world, this monograph includes:  \u003c\/p\u003e\u003cul\u003e\n\u003cli\u003eA thorough introduction to microRNAs as non-invasive biomarkers of toxicity and chemical hazard\u003c\/li\u003e \u003cli\u003eComprehensive explorations of extracellular vesicle-associated miRNAs as toxic biomarkers, as well as transcriptomic applications in toxicology and medicine\u003c\/li\u003e \u003cli\u003ePractical discussions of circulating miRNAs as biomarkers of metal exposure, as well as microRNAs biomarkers of malignant mesothelioma\u003c\/li\u003e \u003cli\u003eIn-depth examinations of the role of noncoding RNAs in innate immune responses perturbed by environmental arsenic with a focus on microRNAs\u003c\/li\u003e\n\u003c\/ul\u003e \u003cp\u003ePerfect for researchers, toxicologists, risk assessors, and regulators, \u003ci\u003eGenomic and Epigenomic Biomarkers of Toxicology and Disease: Clinical and Therapeutic Actions\u003c\/i\u003e will also earn a place in the libraries of graduate students with an interest in biomarkers, toxicology, agriculture, or the environment. \u003c\/p\u003e\u003cp\u003eDedication ix\u003c\/p\u003e \u003cp\u003ePreface xi\u003c\/p\u003e \u003cp\u003eAcknowledgements xiii\u003c\/p\u003e \u003cp\u003eList of Contributors xv\u003c\/p\u003e \u003cp\u003e1 Genomic and Epigenomic Biomarkers for Predictive Toxicity and Disease 1\u003cbr\u003e \u003ci\u003eSaura C. Sahu\u003c\/i\u003e\u003c\/p\u003e \u003cp\u003e2 MicroRNAs as Non-invasive Biomarkers of Toxicity and Chemical Hazard: Genomic and Epigenomic Biomarkers of Toxicology and Disease 7\u003cbr\u003e \u003ci\u003eGail M. Nelson and Brian N. Chorley\u003c\/i\u003e\u003c\/p\u003e \u003cp\u003e3 EV (Extracellular Vesicle)-associated miRNAs as Biomarkers of Toxicity 37\u003cbr\u003e \u003ci\u003eRyuichi Ono, Yusuke Yoshioka, Yusuke Furukawa, Mie Naruse, Makiko Kuwagata, Takahiro Ochiya, Satoshi Kitajima, and Yoko Hirabayashi\u003c\/i\u003e\u003c\/p\u003e \u003cp\u003e4 Circulating miRNAs as Biomarkers of Toxic Heavy Metal Exposure 63\u003cbr\u003e \u003ci\u003eAlexandra N. Nail, Ana P. Ferragut Cardoso, Mayukh Banerjee, and J. Christopher States\u003c\/i\u003e\u003c\/p\u003e \u003cp\u003e5 MicroRNA Biomarkers of Malignant Mesothelioma 89\u003cbr\u003e \u003ci\u003eLijin Zhu, Fangfang Zhang, Min Zhang, Hailing Xia, Xiuyuan Yuan, and Yanan Gao\u003c\/i\u003e\u003c\/p\u003e \u003cp\u003e6 Role of Non-coding RNAs in Innate Immune Responses Perturbed by Environmental Arsenic Exposure 101\u003cbr\u003e \u003ci\u003eLiz Saavedra Perez and Benjamin L. King\u003c\/i\u003e\u003c\/p\u003e \u003cp\u003e7 Transcriptomics: Applications in Toxicology and Medicine 133\u003cbr\u003e \u003ci\u003ePius Joseph Copyrighted Material\u003c\/i\u003e\u003c\/p\u003e \u003cp\u003e8 Network Biology for Biomarker Discovery and Therapy in Cancer 163\u003cbr\u003e \u003ci\u003eAsim Bikas Das\u003c\/i\u003e\u003c\/p\u003e \u003cp\u003e9 Epigenetic Biomarkers: Link to Maternal Exposure and Offspring Health Outcomes 185\u003cbr\u003e \u003ci\u003eJairus Pulczinski, Moira Mccormick, Yuchen Sun, Musa Watfa, Robert YS Cheng, and Wan-Yee Tang\u003c\/i\u003e\u003c\/p\u003e \u003cp\u003e10 The Role of Dynamic Epigenetic Changes in Modulating Homeostasis after Exposure to Low-dose Environmental Chemicals 213\u003cbr\u003e \u003ci\u003eChongli Yuan, Jennifer L. Freeman, Junkai Xie, and Han Zhao\u003c\/i\u003e\u003c\/p\u003e \u003cp\u003e11 Emerging Non-invasive Molecular Biomarkers for Early Cancer Detection 229\u003cbr\u003e \u003ci\u003eJacob Sobota, Yingxue Zhang, Eid Alshammari,and Zhe Yang\u003c\/i\u003e\u003c\/p\u003e \u003cp\u003e12 Aberrant DNA Methylation of Tumor Suppressor Genes and Oncogenes as Cancer Biomarkers 251\u003cbr\u003e \u003ci\u003eEid Alshammari, Yingxue Zhang, Jacob Sobota, and Zhe Yang\u003c\/i\u003e\u003c\/p\u003e \u003cp\u003e13 SMYD Protein Family as Promising Biomarkers for Cancer Diagnosis and Prognosis 273\u003cbr\u003e \u003ci\u003eYingxue Zhang, Eid Alshammari, Jacob Sobota, and Zhe Yang\u003c\/i\u003e\u003c\/p\u003e \u003cp\u003e14 Toward Precision Medicine: Epigenetic Alterations in Human Melanoma 309\u003cbr\u003e \u003ci\u003eCarmen Elena Condrat, Elena Codruta Dobrica, Sanda Maria Cretoiu, and Dragos Cretoiu\u003c\/i\u003e\u003c\/p\u003e \u003cp\u003e15 Currents Trends and Future Perspectives in Our Epigenetic Signatures: What a Diet Can Trigger 333\u003cbr\u003e \u003ci\u003eElena-Codruța Dobrică, Mihnea-Alexandru Găman, Matei-Alexandru Cozma, and Sanda Maria Cretoiu\u003c\/i\u003e\u003c\/p\u003e \u003cp\u003e16 Genetic and Epigenetic Biomarkers of Organophosphate Compounds, Dialkyl Phosphate Exposure, and Their Relation to Biological Effects 363\u003cbr\u003e \u003ci\u003eDavid S. Hernández-Toledano and Libia Vega\u003c\/i\u003e\u003c\/p\u003e \u003cp\u003e17 Genetic, Epigenetic, and Anatomical Factors in Agenesis and Development of Female Reproductive Tract 383\u003cbr\u003e \u003ci\u003eTadaaki Nakajima, Tomomi Sato, and Taisen Iguchi\u003c\/i\u003e\u003c\/p\u003e \u003cp\u003e18 Cause or Consequence: Epigenomic DNA Methylation Changes in Arsenic- Mediated in Vitro Transformation of Human Prostate Cells 395\u003cbr\u003e \u003ci\u003eB. Alex Merrick, Dhiral P. Phadke, Ruchir R. Shah, Deepak Mav, and Erik J. Tokar\u003c\/i\u003e\u003c\/p\u003e \u003cp\u003e19 Epigenetic Regulation of Sex Determination and Toxicity in Nonmammalian Vertebrates 415\u003cbr\u003e \u003ci\u003eGenki Yamagishi, Taisen Iguchi, and Shinichi Miyagawa\u003c\/i\u003e\u003c\/p\u003e \u003cp\u003e20 Characterization of Genomic and Epigenomic Biomarkers of Nanoparticle Toxicity Using the Zebrafish Model System 449\u003cbr\u003e \u003ci\u003eAthira Sairanthry Suku, Parayanthala Valappil Mohanan, and Jennifer L. Freeman\u003c\/i\u003e\u003c\/p\u003e \u003cp\u003eIndex 477\u003c\/p\u003e \u003cp\u003e\u003cb\u003eSaura C. Sahu, PhD,\u003c\/b\u003e is a former Research Chemist with the Division of Toxicology at the Office of Applied Research and Safety Assessment, Center for Food Safety and Applied Nutrition at the United States Food and Drug Administration. \u003c\/p\u003e  \u003cp\u003e\u003cb\u003eThe latest developments in biomarker research applicable to toxicology and medicine\u003c\/b\u003e\u003c\/p\u003e \u003cp\u003eResearch on genomic and epigenomic biomarkers is developing rapidly with cutting-edge studies scattered throughout the academic literature, making the status of ongoing scientific activity in this area difficult to ascertain.  \u003c\/p\u003e\u003cp\u003e\u003ci\u003eGenomic and Epigenomic Biomarkers of Toxicology and Disease: Clinical and Therapeutic Actions\u003c\/i\u003e delivers a comprehensive and authoritative compilation of up-to-date developments in the application of genomic and epigenomic biomarkers to toxicology, disease prevention, cancer detection, therapeutics, gene therapy, and other areas. With contributions from a collection of internationally recognized investigators, this edited volume offers unique insights into current trends and future directions of research in the discussed areas.  \u003c\/p\u003e\u003cp\u003e Combining state-of-the-art information on genomic and epigenomic biomarkers from a range of specialists from around the world, this monograph includes:  \u003c\/p\u003e\u003cul\u003e\n\u003cli\u003eA thorough introduction to microRNAs as non-invasive biomarkers of toxicity and chemical hazard\u003c\/li\u003e \u003cli\u003eComprehensive explorations of extracellular vesicle-associated miRNAs as toxic biomarkers, as well as transcriptomic applications in toxicology and medicine\u003c\/li\u003e \u003cli\u003ePractical discussions of circulating miRNAs as biomarkers of metal exposure, as well as microRNAs biomarkers of malignant mesothelioma\u003c\/li\u003e \u003cli\u003eIn-depth examinations of the role of noncoding RNAs in innate immune responses perturbed by environmental arsenic with a focus on microRNAs\u003c\/li\u003e\n\u003c\/ul\u003e \u003cp\u003ePerfect for researchers, toxicologists, risk assessors, and regulators, \u003ci\u003eGenomic and Epigenomic Biomarkers of Toxicology and Disease: Clinical and Therapeutic Actions\u003c\/i\u003e will also earn a place in the libraries of graduate students with an interest in biomarkers, toxicology, agriculture, or the environment.\u003c\/p\u003e","brand":"Wiley","offers":[{"title":"Default Title","offer_id":47989279424741,"sku":"NP9781119807674","price":230.0,"currency_code":"USD","in_stock":false}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/1842\/7735\/files\/9781119807674.jpg?v=1761783494","url":"https:\/\/k12savings.com\/es\/products\/genomic-and-epigenomic-biomarkers-of-toxicology-and-disease-isbn-9781119807674","provider":"K12savings","version":"1.0","type":"link"}