Fundamentals of Biochemistry, Student Companion

This is the Student Companion to accompany Fundamentals of Biochemistry, 5th Edition.

Voet, Voet and Pratt’s Fundamentals of Biochemistry, 5th Edition addresses the enormous advances in biochemistry, particularly in the areas of structural biology and Bioinformatics, by providing a solid biochemical foundation that is rooted in chemistry to prepare students for the scientific challenges of the future. While continuing in its tradition of presenting complete and balanced coverage that is clearly written and relevant to human health and disease, Fundamentals of Biochemistry, 5e includes new pedagogy and enhanced visuals that provide a pathway for student learning.

2 Water 9

3 Nucleotides, Nucleic Acids, and Genetic Information 21

4 Amino Acids 29

5 Proteins: Primary Structure 40

6 Proteins: Three-Dimensional Structure 49

7 Protein Function: Myoglobin and Hemoglobin, Muscle Contraction, and Antibodies 60

8 Carbohydrates 72

9 Lipids and Biological Membranes 80

10 Membrane Transport 90

11 Enzymatic Catalysis 96

12 Enzyme Kinetics, Inhibition, and Control 108

13 Biochemical Signaling 121

14 Introduction to Metabolism 128

15 Glucose Catabolism 137

16 Glycogen Metabolism and Gluconeogenesis 146

17 Citric Acid Cycle 154

18 Electron Transport and Oxidative Phosphorylation 160

19 Photosynthesis 169

20 Lipid Metabolism 176

21 Amino Acid Metabolism 188

22 Mammalian Fuel Metabolism: Integration and Regulation 197

23 Nucleotide Metabolism 203

24 Nucleic Acid Structure 210

25 DNA Replication, Repair, and Recombination 219

26 Transcription and RNA Processing 230

27 Protein Synthesis 238

28 Regulation of Gene Expression 247

Answers to Questions AQ-1

Solutions to Problems SP-1

Donald Voet received a Ph.D. in chemistry from Harvard University and did postdoctoral research in the Biology Department at MIT. Don took up a faculty position in the department of chemistry at the University of Pennsylvania, upon completing his postdoctoral work. He has been a visiting scholar at Oxford University, the University of California San Diego, and the Weismann Institute of Science in Israel.

Judith Voet received her Ph.D. from Brandeis University and did postdoctoral research at the University of Pennsylvania, Haverford College and the Fox Chase Cancer Center. She taught at the University of Delaware before moving to Swarthmore College. Together with Don Voet, she is Co-Editor-in-Chief of the journal Biochemistry and Molecular Biology Education.