{"product_id":"experimental-organic-chemistry-isbn-9781119952381","title":"Experimental Organic Chemistry","description":"\u003cp\u003e\u003cb\u003eThe definitive guide to the principles and practice of experimental organic chemistry — fully updated and now featuring more than 100 experiments\u003c\/b\u003e\u003c\/p\u003e \u003cp\u003eThe latest edition of this popular guide to experimental organic chemistry takes students from their first day in the laboratory right through to complex research procedures. All sections have been updated to reflect new techniques, equipment and technologies, and the text has been revised with an even sharper focus on practical skills and procedures.\u003c\/p\u003e \u003cp\u003eThe first half of the book is devoted to safe laboratory practice as well as purification and analytical techniques; particularly spectroscopic analysis. The second half contains step-by-step experimental procedures, each one illustrating a basic principle, or important reaction type. Tried and tested over almost three decades, over 100 validated experiments are graded according to their complexity and all are chosen to highlight important chemical transformations and to teach key experimental skills.\u003c\/p\u003e \u003cp\u003eNew sections cover updated health and safety guidelines, additional spectroscopic techniques, electronic notebooks and record keeping, and techniques, such as semi-automated chromatography and enabling technologies such as the use of microwave and flow chemistry. New experiments include transition metal-catalysed cross-coupling, organocatalysis, asymmetric synthesis, flow chemistry, and microwave-assisted synthesis. Key aspects of this third edition include:\u003c\/p\u003e \u003cul\u003e \u003cli\u003eDetailed descriptions of the correct use of common apparatus used in the organic laboratory\u003c\/li\u003e \u003cli\u003eOutlines of practical skills that all chemistry students must learn\u003c\/li\u003e \u003cli\u003eHighlights of aspects of health and safety in the laboratory, both in the first section and throughout the experimental procedures\u003c\/li\u003e \u003cli\u003eFour new sections reflecting advances in techniques and technologies, from electronic databases and information retrieval to semi-automated chromatography\u003c\/li\u003e \u003cli\u003eMore than 100 validated experiments of graded complexity from introductory to research level\u003c\/li\u003e \u003cli\u003eA user-friendly experiment directory\u003c\/li\u003e \u003cli\u003eAn instructor manual and PowerPoint slides of the figures in the book available on a companion website\u003c\/li\u003e \u003c\/ul\u003e \u003cp\u003eA comprehensive guide to contemporary organic chemistry laboratory principles, procedures, protocols, tools and techniques, \u003ci\u003eExperimental Organic Chemistry, Third Edition \u003c\/i\u003eis both an essential laboratory textbook for students of chemistry at all levels, and a handy bench reference for experienced chemists.\u003c\/p\u003eDieses renommierte Fachbuch steht für einen genauen Überblick über die Prinzipien und Verfahren der experimentellen organischen Chemie und begleitet Studenten von ihrem ersten Labortag bis in die Forschung. Im gesamten Buch findet man Ansätze aus dem Mikrobereich, neben herkömmlichen Verfahren und in Einklang mit aktuellen Laborpraktiken.\u003cbr\u003e \u003cbr\u003e Die erste Hälfte des Buchs beschäftigt sich mit sämtlichen Aspekten sicherer Laborverfahren, dem Einsatz einer Vielzahl von Reinigungs- und Analysetechniken, vor allem der spektroskopischen Analyse. In der zweiten Hälfte werden einfach nachvollziehbare experimentelle Verfahren beschrieben, die jeweils einen wichtigen Reaktionstyp oder ein grundlegendes Prinzip der organischen Chemie beleuchten. Diese in den vergangenen zwei Jahrzehnten bewährten Experimente werden nach ihrer Komplexität eingestuft und zu vielen gibt es Entsprechungen im Mikrobereich. Besonders wichtig: Im dem Buch werden Aspekte des Arbeitsschutzes hervorgehoben.\u003cbr\u003e \u003cbr\u003e In der 3. Auflage von Experimental Organic Chemistry wurden sämtliche Kapitel gründlich überarbeitet und enthalten Informationen zu neuen Verfahren und neuer Ausrüstung. Der Schwerpunkt liegt verstärkt auf praktischen Fertigkeiten, Verfahren und Tipps. Die Anzahl der Experimente wurde auf über 100 bewährte Verfahren erhöht. Zu den neuen Experimenten gehören übergangsmetallkatalysierte metallorganische Reaktionen, Festkörper-Peptidkupplung, asymmetrische Synthese, Epoxidierung und mikrowellengestützte Chromatographie. Neue Kapitel zu Datenbanken und Datenabruf, elektronischen Notebooks und Datenaufbewahrung, Modellierung\/Simulation als hilfreiche Laborwerkzeuge sowie zu modernen Verfahren wie halbautomatische Chromatographie. \u003cbr\u003e Experimental Organic Chemistry ist ein wichtiges Laborhandbuch für alle Studenten der Chemie und ein praktisches Nachschlagewerk für erfahrene Chemiker.\u003cbr\u003e \u003cp\u003eAbout the authors ix\u003c\/p\u003e \u003cp\u003e Preface to the third edition xi\u003c\/p\u003e \u003cp\u003eAbout the companion website xv\u003c\/p\u003e \u003cp\u003e\u003cb\u003ePart 1: Laboratory Practice 1\u003c\/b\u003e\u003c\/p\u003e \u003cp\u003e\u003cb\u003e1 Safety in the chemical laboratory 3\u003c\/b\u003e\u003c\/p\u003e \u003cp\u003e1.1 Essential rules for laboratory safety 4\u003c\/p\u003e \u003cp\u003e1.2 Hazardous chemicals 7\u003c\/p\u003e \u003cp\u003e1.3 Disposal of hazardous waste 11\u003c\/p\u003e \u003cp\u003e1.4 Accident procedures 12\u003c\/p\u003e \u003cp\u003e\u003cb\u003e2 Glassware and equipment in the laboratory 15\u003c\/b\u003e\u003c\/p\u003e \u003cp\u003e2.1 Glass equipment 16\u003c\/p\u003e \u003cp\u003e2.2 Hardware 21\u003c\/p\u003e \u003cp\u003e2.3 Heating 24\u003c\/p\u003e \u003cp\u003e2.4 Stirring 30\u003c\/p\u003e \u003cp\u003e2.5 Vacuum pumps 32\u003c\/p\u003e \u003cp\u003e2.6 The rotary evaporator 42\u003c\/p\u003e \u003cp\u003e2.7 Catalytic hydrogenation 46\u003c\/p\u003e \u003cp\u003e2.8 Ozonolysis 48\u003c\/p\u003e \u003cp\u003e2.9 Irradiation 50\u003c\/p\u003e \u003cp\u003e2.10 Compressed gases 54\u003c\/p\u003e \u003cp\u003e\u003cb\u003e3 Organic reactions: From starting materials to pure organic product 61\u003c\/b\u003e\u003c\/p\u003e \u003cp\u003e3.1 Handling chemicals 62\u003c\/p\u003e \u003cp\u003e3.2 The reaction 81\u003c\/p\u003e \u003cp\u003e3.3 Purification of organic compounds 105\u003c\/p\u003e \u003cp\u003e\u003cb\u003e4 Qualitative analysis of organic compounds 185\u003c\/b\u003e\u003c\/p\u003e \u003cp\u003e4.1 Purity 185\u003c\/p\u003e \u003cp\u003e4.2 Determination of structure using chemical methods 202\u003c\/p\u003e \u003cp\u003e\u003cb\u003e5 Spectroscopic analysis of organic compounds 207\u003c\/b\u003e\u003c\/p\u003e \u003cp\u003e5.1 Absorption spectroscopy 207\u003c\/p\u003e \u003cp\u003e5.2 Infrared spectroscopy 209\u003c\/p\u003e \u003cp\u003e5.3 Nuclear magnetic resonance spectroscopy 227\u003c\/p\u003e \u003cp\u003e5.4 Ultraviolet spectroscopy 279\u003c\/p\u003e \u003cp\u003e5.5 Mass spectrometry 295\u003c\/p\u003e \u003cp\u003e\u003cb\u003e6 Keeping records: The laboratory notebook and chemical literature 311\u003c\/b\u003e\u003c\/p\u003e \u003cp\u003e6.1 The laboratory notebook 312\u003c\/p\u003e \u003cp\u003e6.2 The research report 322\u003c\/p\u003e \u003cp\u003e6.3 The chemical literature 327\u003c\/p\u003e \u003cp\u003e\u003cb\u003ePart 2: Experimental Procedures 329\u003c\/b\u003e\u003c\/p\u003e \u003cp\u003eIntroduction 331\u003c\/p\u003e \u003cp\u003eList of experiments 333\u003c\/p\u003e \u003cp\u003eExperiments that can be taken in sequence 353\u003c\/p\u003e \u003cp\u003eExperiments that can be used to compare directly different techniques for undertaking a reaction 354\u003c\/p\u003e \u003cp\u003eExperiments that illustrate particular techniques 354\u003c\/p\u003e \u003cp\u003e\u003cb\u003e7 Functional group interconversions 355\u003c\/b\u003e\u003c\/p\u003e \u003cp\u003e7.1 Simple transformations 355\u003c\/p\u003e \u003cp\u003e7.2 Reactions of alkenes 366\u003c\/p\u003e \u003cp\u003e7.3 Substitution 386\u003c\/p\u003e \u003cp\u003e7.4 Reduction 390\u003c\/p\u003e \u003cp\u003e7.5 Oxidation 424\u003c\/p\u003e \u003cp\u003e7.6 Rearrangements 436\u003c\/p\u003e \u003cp\u003e\u003cb\u003e8 Carbon–carbon bond‐forming reactions 443\u003c\/b\u003e\u003c\/p\u003e \u003cp\u003e8.1 Grignard and organolithium reagents 444\u003c\/p\u003e \u003cp\u003e8.2 Enolate anions 456\u003c\/p\u003e \u003cp\u003e8.3 Heteroatom‐stabilized carbanions 484\u003c\/p\u003e \u003cp\u003e8.4 Aromatic electrophilic substitution 504\u003c\/p\u003e \u003cp\u003e8.5 Pericyclic reactions 514\u003c\/p\u003e \u003cp\u003e8.6 Metal‐mediated coupling reactions 534\u003c\/p\u003e \u003cp\u003e\u003cb\u003e9 Experiments using enabling technologies 545\u003c\/b\u003e\u003c\/p\u003e \u003cp\u003e9.1 Microwave chemistry 545\u003c\/p\u003e \u003cp\u003e9.2 Flow chemistry 554\u003c\/p\u003e \u003cp\u003e\u003cb\u003e10 Projects 569\u003c\/b\u003e\u003c\/p\u003e \u003cp\u003e10.1 Natural product isolation and identification 569\u003c\/p\u003e \u003cp\u003e10.2 Project in organic synthesis 578\u003c\/p\u003e \u003cp\u003e10.3 Aspects of physical organic chemistry 608\u003c\/p\u003e \u003cp\u003eAppendices 627\u003c\/p\u003e \u003cp\u003eOrganic solvents 629\u003c\/p\u003e \u003cp\u003eSpectroscopic correlation tables 635\u003c\/p\u003e \u003cp\u003eIndex of chemicals 649\u003c\/p\u003e \u003cp\u003eGeneral index 657\u003c\/p\u003e \u003cp\u003e \u003c\/p\u003e   \u003cp\u003e\u003cb\u003e Philippa B. Cranwell, PhD\u003c\/b\u003e is a Lecturer in the Department of Chemistry, University of Reading, UK.   \u003c\/p\u003e\u003cp\u003e\u003cb\u003e Laurence M. Harwood, PhD\u003c\/b\u003e is Professor of Organic Chemistry in the Department of Chemistry and Director of the Chemical Analysis Facility, University of Reading, UK.   \u003c\/p\u003e\u003cp\u003e\u003cb\u003e Christopher J. Moody, PhD\u003c\/b\u003e is Sir Jesse Boot Professor in the School of Chemistry, University of Nottingham, UK.    \u003c\/p\u003e\u003cp\u003e\u003cb\u003eThe definitive guide to the principles and practice of experimental organic chemistry – fully updated and now featuring more than 100 experiments\u003c\/b\u003e\u003c\/p\u003e \u003cp\u003eThe latest edition of this popular guide to experimental organic chemistry takes students from their first day in the laboratory right through to complex research procedures. All sections have been updated to reflect new techniques, equipment and technologies, and the text has been revised with an even sharper focus on practical skills and procedures.\u003c\/p\u003e \u003cp\u003eThe first half of the book is devoted to safe laboratory practice as well as purification and analytical techniques; particularly spectroscopic analysis. The second half contains step-by-step experimental procedures, each one illustrating a basic principle, or important reaction type. Tried and tested over almost three decades, over 100 validated experiments are graded according to their complexity and all are chosen to highlight important chemical transformations and to teach key experimental skills.\u003c\/p\u003e \u003cp\u003eNew sections cover updated health and safety guidelines, additional spectroscopic techniques, electronic notebooks and record keeping, and techniques, such as semi-automated chromatography and enabling technologies such as the use of microwave and flow chemistry. New experiments include transition metal-catalysed cross-coupling, organocatalysis, asymmetric synthesis, flow chemistry, and microwave-assisted synthesis. Key aspects of this third edition include:\u003c\/p\u003e \u003cp\u003e• Detailed descriptions of the correct use of common apparatus used in the organic laboratory\u003cbr\u003e• Outlines of practical skills that all chemistry students must learn\u003cbr\u003e• Highlights of aspects of health and safety in the laboratory, both in the first section and throughout the experimental procedures \u003cbr\u003e• Four new sections reflecting advances in techniques and technologies, from electronic databases and information retrieval to semi-automated chromatography\u003cbr\u003e• More than 100 validated experiments of graded complexity from introductory to research level \u003cbr\u003e• A user-friendly experiment directory\u003cbr\u003e• An instructor manual and PowerPoint slides of the figures in the book available on a companion website\u003c\/p\u003e \u003cp\u003eA comprehensive guide to contemporary organic chemistry laboratory principles, procedures, protocols, tools and techniques, \u003ci\u003eExperimental Organic Chemistry, Third Edition\u003c\/i\u003e is both an essential laboratory textbook for students of chemistry at all levels, and a handy bench reference for experienced chemists.\u003c\/p\u003e","brand":"Wiley","offers":[{"title":"Default Title","offer_id":47989186003173,"sku":"NP9781119952381","price":57.0,"currency_code":"USD","in_stock":false}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/1842\/7735\/files\/9781119952381.jpg?v=1761783132","url":"https:\/\/k12savings.com\/es\/products\/experimental-organic-chemistry-isbn-9781119952381","provider":"K12savings","version":"1.0","type":"link"}