{"product_id":"evolution-after-gene-duplication-isbn-9780470593820","title":"Evolution after Gene Duplication","description":"Gene duplication has long been believed to have played a major role in the rise of biological novelty through evolution of new function and gene expression patterns. The first book to examine gene duplication across all levels of biological organization, \u003ci\u003eEvolution after Gene Duplication\u003c\/i\u003e presents a comprehensive picture of the mechanistic process by which gene duplication may have played a role in generating biodiversity.  \u003cp\u003eKey Features:\u003c\/p\u003e \u003cul type=\"disc\"\u003e \u003cli\u003eExplores comparative genomics, genome evolution studies and analysis of multi-gene families such as \u003ci\u003eHox\u003c\/i\u003e, globins, olfactory receptors and MHC (immune system)\u003c\/li\u003e \u003cli\u003eA complete post-genome treatment of the topic originally covered by Ohno's 1970 classic, this volume extends coverage to include the fate of associated regulatory pathways\u003c\/li\u003e \u003cli\u003eTaps the significant increase in multi-gene family data that has resulted from comparative genomics\u003c\/li\u003e \u003cli\u003eComprehensive coverage that includes opposing theoretical viewpoints, comparative genomics data, theoretical and empirical evidence and the role of bioinformatics in the study of gene duplication\u003c\/li\u003e \u003c\/ul\u003e \u003cp\u003eThis up-to-date overview of theory and mathematical models along with practical examples is suitable for scientists across various levels of biology as well as instructors and graduate students.\u003c\/p\u003e \u003cp\u003eContributors vii\u003c\/p\u003e \u003cp\u003ePreface xi\u003c\/p\u003e \u003cp\u003e1 Understanding Gene Duplication Through Biochemistry and Population Genetics 1\u003cbr\u003e\u003ci\u003eDavid A. Liberles, Grigory Kolesov, and Katharina Dittmar\u003c\/i\u003e\u003c\/p\u003e \u003cp\u003e2 Functional Divergence of Duplicated Genes 23\u003cbr\u003e\u003ci\u003eTakashi Makino, David G. Knowles, and Aoife McLysaght\u003c\/i\u003e\u003c\/p\u003e \u003cp\u003e3 Duplicate Retention After Small- and Large-Scale Duplications 31\u003cbr\u003e\u003ci\u003eSteven Maere and Yves Van de Peer\u003c\/i\u003e\u003c\/p\u003e \u003cp\u003e4 Gene Dosage and Duplication 57\u003cbr\u003e\u003ci\u003eFyodor A. Kondrashov\u003c\/i\u003e\u003c\/p\u003e \u003cp\u003e5 Myths and Realities of Gene Duplication 77\u003cbr\u003e\u003ci\u003eAustin L. Hughes and Robert Friedman\u003c\/i\u003e\u003c\/p\u003e \u003cp\u003e6 Evolution After \u003ci\u003eand \u003c\/i\u003eBefore Gene Duplication? 105\u003cbr\u003e\u003ci\u003eTobias Sikosek and Erich Bornberg-Bauer\u003c\/i\u003e\u003c\/p\u003e \u003cp\u003e7 Protein Products of Tandem Gene Duplication: A Structural View 133\u003cbr\u003e\u003ci\u003eWilliam R. Taylor and Michael I. Sadowski\u003c\/i\u003e\u003c\/p\u003e \u003cp\u003e8 Statistical Methods for Detecting Functional Divergence of Gene Families 163\u003cbr\u003e\u003ci\u003eXun Gu\u003c\/i\u003e\u003c\/p\u003e \u003cp\u003e9 Mapping Gene Gains and Losses Among Metazoan Full Genomes Using an Integrated Phylogenetic Framework 173\u003cbr\u003e\u003ci\u003eAthanasia C. Tzika, Rapha¨el Helaers, and Michel C. Milinkovitch\u003c\/i\u003e\u003c\/p\u003e \u003cp\u003e10 Reconciling Phylogenetic Trees 185\u003cbr\u003e\u003ci\u003eOliver Eulenstein, Snehalata Huzurbazar, and David A. Liberles\u003c\/i\u003e\u003c\/p\u003e \u003cp\u003e11 On the Energy and Material Cost of Gene Duplication 207\u003cbr\u003e\u003ci\u003eAndreas Wagner\u003c\/i\u003e\u003c\/p\u003e \u003cp\u003e12 Fate of a Duplicate in a Network Context 215\u003cbr\u003e\u003ci\u003eOrkun S. Soyer\u003c\/i\u003e\u003c\/p\u003e \u003cp\u003e13 Evolutionary and Functional Aspects of Genetic Redundancy 229\u003cbr\u003e\u003ci\u003eRan Kafri and Tzachi Pilpel\u003c\/i\u003e\u003c\/p\u003e \u003cp\u003e14 Phylogenomic Approach to the Evolutionary Dynamics of Gene Duplication in Birds 253\u003cbr\u003e\u003ci\u003eChris L. Organ, Matthew D. Rasmussen, Maude W. Baldwin, Manolis Kellis, and Scott V. Edwards\u003c\/i\u003e\u003c\/p\u003e \u003cp\u003e15 Gene and Genome Duplications in Plants 269\u003cbr\u003e\u003ci\u003ePamela S. Soltis, J. Gordon Burleigh, Andre S. Chanderbali, Mi-Jeong Yoo, and Douglas E. Soltis\u003c\/i\u003e\u003c\/p\u003e \u003cp\u003e16 Whole Genome Duplications and the Radiation of Vertebrates 299\u003cbr\u003e\u003ci\u003eShigehiro Kuraku and Axel Meyer\u003c\/i\u003e\u003c\/p\u003e \u003cp\u003eIndex 313\u003c\/p\u003e \"This up-to-date overview of theory and mathematical models along with practical examples is suitable for scientists across various levels of biology as well as instructors and graduate students.\" (Forbes.com, 27 October 2010) \u003cp\u003e\u003cb\u003eKatharina Dittmar de la Cruz\u003c\/b\u003e holds both a Ph.D. in Molecular Parisitology and Entomology and a doctorate in Veterinary Medicine, both from the University of Leipzig, Germany. An expert in phylogenetics, molecular evolution, and bioinformatics, she has recently turned her attention toward examining the implications of evolutionary forces on drug design. Dr. Dittmar is an Assistant Professor at the SUNY University at Buffalo.\u003c\/p\u003e \u003cp\u003e\u003cb\u003eDavid Liberles\u003c\/b\u003e earned his Ph.D. in Chemistry at the California Institute of Technology working on the biochemsitry of nucleic acids. Subsequently, he has developed significant expertise in bioinformatics, computational biology and functional genomics. His broad experience includes a professorship at the Stockholm Bioinformatics Center and consultancies with Novo Nordisk and other private research and diagnostic companies. Currently he is Vice-Director of the University of Wyoming Bioinformatics Center and Assistant Professor of Molecular Biology.\u003c\/p\u003e  \u003cp\u003e\u003cb\u003eThe first book to examine gene duplication across all levels of biological organization\u003c\/b\u003e \u003c\/p\u003e\u003cp\u003eThe duplication of genes and genomes has long been postulated to have played a major role in the rise of biological novelty through evolution of new function and gene expression patterns. This biological novelty is represented on multiple levels, ranging from new genes, proteins, network interactions, and expression patterns to new species. \u003ci\u003eEvolution after Gene Duplication\u003c\/i\u003e is the first venue in which gene duplication is examined across all levels of biological organization in order to present a comprehensive picture of the mechanistic process by which gene duplication may have played a part in generating biodiversity. \u003c\/p\u003e\u003cp\u003eBringing together experts from various disciplines, the book: \u003c\/p\u003e\u003cul\u003e \u003cli\u003eLinks the evolutionary process associated with gene duplication through structure to function\u003c\/li\u003e \u003cli\u003eDescribes the link between the process of gene duplication and protein structure\u003c\/li\u003e \u003cli\u003ePresents a procedure for linking changes in gene copy number through evolution to functional and gene expression evolution\u003c\/li\u003e \u003cli\u003eOffers an overview of model and parsimony-based approaches for gene tree\/species tree reconciliation\u003c\/li\u003e \u003cli\u003eExplains the energetic costs of gene duplication, the interplay between systems- level constraints and duplicate gene retention, and the complementary interplay between duplication and the structure of biological networks\u003c\/li\u003e \u003cli\u003eExplores comparative genomics, genome evolution studies, and analysis of multi-gene families such as \u003ci\u003eHox\u003c\/i\u003e, globins, olfactory receptors, and MHC (immune system)\u003c\/li\u003e \u003cli\u003eTaps the significant increase in multi-gene family data that has resulted from comparative genomics\u003c\/li\u003e \u003cli\u003eFeatures opposing theoretical viewpoints, comparative genomics data, theoretical and empirical evidence, and the role of bioinformatics in the study of gene duplication\u003c\/li\u003e \u003cli\u003eIncludes the fate of associated regulatory pathways\u003c\/li\u003e \u003c\/ul\u003e \u003cp\u003eOrganized into five sections, the book lays out a hierarchy of chapters extending from evolutionary principles and molecular details to increasingly higher levels of biological organization, a design intended to help the reader appreciate the interconnectedness of these levels. There is also an up-to-date overview of theory, mathematical models, and practical examples spanning research fields such as biophysics, biochemistry, bioinformatics, molecular biology, and systematics. \u003c\/p\u003e\u003cp\u003e\u003ci\u003eEvolution after Gene Duplication\u003c\/i\u003e is suitable for scientists across various levels of biology as well as instructors and graduate students. It is pertinent to anyone involved in comparative genomics, genome evolution studies, or analysis of any of the multi-gene families.\u003c\/p\u003e","brand":"Wiley-Blackwell","offers":[{"title":"Default Title","offer_id":47989178859749,"sku":"NP9780470593820","price":136.95,"currency_code":"USD","in_stock":false}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/1842\/7735\/files\/9780470593820.jpg?v=1761783108","url":"https:\/\/k12savings.com\/es\/products\/evolution-after-gene-duplication-isbn-9780470593820","provider":"K12savings","version":"1.0","type":"link"}