Electroanalytical Techniques in Clinical Chemistry and Laboratory Medicine

This practical introduction to all the elextroanalytical techniques that are used in clinical chemistry and laboratory medicine is the only in-depth treatment of the subject available. The author presents the relevant theory and uses numerous examples to illustrate the scope and possibilities of electroanalysis in the clinical laboratory.

The material covered includes the principles and bioanalytical applications of voltammetry and potentiometry, electrochemical biosensors, detectors to flowing steams, and in vivo electrochemistry. The book should be useful to those considering the use of electroanalysis in their laboratories and to clinical chemists experienced in electroanalysisDieser praxisbezogene Überblick über alle in der klinischen Chemie und Labormedizin eingesetzten elektroanalytischen Verfahren ist derzeit das einzige umfassende Werk zu diesem Thema auf dem Markt.

Der Autor stellt die theoretischen Grundlagen vor und verdeutlicht an zahlreichen Beispielen Umfang und Möglichkeiten des Einsatzes elektroanalytischer Verfahren. Einige Stichworte zum Inhalt sind: Prinzipien und bioanalytische Anwendung von Voltametrie und Potentiometrie, elektrochemische Biosensoren sowie in-vivo Elektrochemie.

Das Buch eignet sich gut als Einstieg in das Gebiet, bietet aber auch dem erfahrenen 'Elektroanalytiker' viele Hilfestellungen und Ratschläge. 1. Voltammetry and Other Controlled-Potential Techniques

Introduction

Instrumentation

Sample Consideration

Polarography

AC Voltammetry

Chromoamperometry

Stripping Analysis

Cyclic Voltammetry

Spectroelectrochemistry

Coulometry

2. Ion-Selective Electrodes in Clinical Medicine

Principles of Potentiometric Measurements

Ion-Selective Electrodes in Clinical Analysis

3. Electrochemical Biosensors

Introduction

Enzyme Electrodes

Sensors Based on Other Biocatalytic Layers

Electrochemical Immunosensors

Other Promising Concepts

Conclusion

4. Electrochemical Detection for Liquid Chromatography and Automated Flow Systems

Liquid Chromatography with Electrochemical Detection

Electrochemical Detection for Automated Flow Systems_Clinical Aspects

5. 'In-vivo' Electrochemistry

Introduction

'In-vivo' Voltammetry

Miniature Ion-Selective Electrodes for 'In vivo' Monitoring and Assays of Microliter Samples

Continuous Monitoring Using Non-Invasive Electrochemical Sensors

Conclusion

Subject Index.

JOSEPH WANG, PHD, is Director of the Center for Bioelectronics and Biosensors at the Biodesign Institute and Professor in the Departments of Chemical & Materials Engineering and Chemistry & Biochemistry at Arizona State University. Dr. Wang has authored six books and more than 680 research papers. He holds fifteen patents and is the recipient of the American Chemical Society's Award in Chemical Instrumentation and the Heyrovsky Medal. He was ranked the "Most Cited Electrochemist in the World" in 1995, and was ranked number five on the ISI list of "Most Cited Researchers in Chemistry" for the period 1995 to 2005.