{"product_id":"drug-disposition-and-pharmacokinetics-isbn-9781119588436","title":"Drug Disposition and Pharmacokinetics","description":"\u003cb\u003eDrug Disposition and Pharmacokinetics\u003c\/b\u003e \u003cp\u003e\u003cb\u003eThe most up-to-date edition of a leading reference in drug disposition and pharmacokinetics\u003c\/b\u003e \u003c\/p\u003e\u003cp\u003eIn this new, fully-revised edition of \u003ci\u003eDrug Disposition and Pharmacokinetics: Principles and Applications for Medicine, Toxicology and Biotechnology\u003c\/i\u003e the authors deliver an authoritative and comprehensive discussion of the fate of drug molecules in the body, as well as its implications for pharmacological and clinical effects. The text offers a unique and balanced approach that combines discussion of the specific physical and biological factors affecting the absorption, distribution, metabolism, and excretion of drugs, with mathematical assessments of plasma and body fluid concentrations. The book assumes little prior knowledge and is an ideal reference for practicing professionals in industry as well as researchers and academics. \u003c\/p\u003e\u003cp\u003eThis latest edition provides readers with a new introductory chapter, as well as new chapters covering monoclonal antibodies, the role of stereochemistry in drug disposition and pharmacokinetics, DMPK in non-human species, and the recent use of AI in drug development. Readers will also find: \u003c\/p\u003e\u003cul\u003e\n\u003cli\u003e Thorough introductions to drug disposition, pharmacokinetics, and pharmacokinetic modeling\u003c\/li\u003e \u003cli\u003e In-depth treatments of the kinetics of drug elimination and the relationship between concentration and effect, including PK–PD modeling\u003c\/li\u003e \u003cli\u003e Comprehensive discussions of predictive pharmacokinetics and the disposition of biological molecules, including peptides and monoclonal antibodies\u003c\/li\u003e \u003cli\u003e Detailed examinations of the effects of sex, pregnancy, age, and disease, as well as drug monitoring in therapeutics and the use of AI in drug development and treatment\u003c\/li\u003e\n\u003c\/ul\u003e \u003cp\u003ePerfect for professionals and researchers working with the scientific aspects of drug disposition in human and veterinary medicine, toxicology, and pharmacology. \u003ci\u003eDrug Disposition and Pharmacokinetics\u003c\/i\u003e will earn a place in the libraries of students of senior-level courses in pharmacy. \u003c\/p\u003e\u003cp\u003ePreface\u003c\/p\u003e \u003cp\u003e1 Setting the Scene: Concepts, Nature of Drugs and Quality of Results\u003c\/p\u003e \u003cp\u003e2 Drug Disposition and Fate\u003c\/p\u003e \u003cp\u003e3 Pharmacokinetic Modelling\u003c\/p\u003e \u003cp\u003e4 Pharmacokinetics of Metabolism and Excretion\u003c\/p\u003e \u003cp\u003e5 Quantitative Pharmacological Relationships\u003c\/p\u003e \u003cp\u003e6 Predictive Pharmacokinetics\u003c\/p\u003e \u003cp\u003e7 Disposition of Peptides and Other Biological Molecules\u003c\/p\u003e \u003cp\u003e8 Monoclonal Antibodies\u003c\/p\u003e \u003cp\u003e9 Drug Metabolism and Pharmacokinetics in Veterinary Sciences\u003c\/p\u003e \u003cp\u003e10 Factors Affecting Plasma Concentrations. Consideration of Special Populations.\u003c\/p\u003e \u003cp\u003e11 Pharmacogenetics, Pharmacogenomics and Precision Medicine\u003c\/p\u003e \u003cp\u003e12 Effects of Sex and Pregnancy on Drug Disposition and Pharmacokinetics\u003c\/p\u003e \u003cp\u003e13 Developmental Pharmacology and Age-related Phenomena\u003c\/p\u003e \u003cp\u003e14 Effects of Disease on Drug Disposition and Pharmacokinetics\u003c\/p\u003e \u003cp\u003e15 Role of Stereochemistry in Drug Disposition and Pharmacokinetics\u003c\/p\u003e \u003cp\u003e16 Drug Metabolism and Pharmacokinetics in Drug Interactions and Toxicity\u003c\/p\u003e \u003cp\u003e17 Drug Monitoring in Therapeutics\u003c\/p\u003e \u003cp\u003e18 From Antiquity to the Age of Artificial Intelligence: Reflections on the Past, Present and Future of Drug Disposition and Pharmacokinetics\u003c\/p\u003e \u003cp\u003eIndex\u003c\/p\u003e  \u003cp\u003e\u003cb\u003eStephen H. Curry, PhD, D.Sc. (Med.),\u003c\/b\u003e has held professorial positions in Pharmacology, Physiology and Pharmaceutical Sciences at the Universities of London, Florida, and Rochester, as well as posts in the pharmaceutical industry. He is a Fellow of the Royal Pharmaceutical Society, and currently works in the field of technology transfer and translational science with a primary interest in aiding university scientists with commercialization of patented medically-significant discoveries. He is based in Rochester, New York. \u003c\/p\u003e\u003cp\u003e\u003cb\u003eRobin Whelpton, PhD,\u003c\/b\u003e has taught undergraduate and postgraduate students of medicine, dentistry, pharmacology, analytical toxicology, pharmaceutical chemistry, and biomedical sciences at Queen Mary, University of London.   \u003c\/p\u003e\u003cp\u003e\u003cb\u003eThe most up-to-date edition of a leading reference in drug disposition and pharmacokinetics\u003c\/b\u003e \u003c\/p\u003e\u003cp\u003eIn this new, fully-revised edition of \u003ci\u003eDrug Disposition and Pharmacokinetics: Principles and Applications for Medicine, Toxicology and Biotechnology\u003c\/i\u003e the authors deliver an authoritative and comprehensive discussion of the fate of drug molecules in the body, as well as its implications for pharmacological and clinical effects. The text offers a unique and balanced approach that combines discussion of the specific physical and biological factors affecting the absorption, distribution, metabolism, and excretion of drugs, with mathematical assessments of plasma and body fluid concentrations. The book assumes little prior knowledge and is an ideal reference for practicing professionals in industry as well as researchers and academics. \u003c\/p\u003e\u003cp\u003eThis latest edition provides readers with a new introductory chapter, as well as new chapters covering monoclonal antibodies, the role of stereochemistry in drug disposition and pharmacokinetics, DMPK in non-human species, and the recent use of AI in drug development. Readers will also find: \u003c\/p\u003e\u003cul\u003e\n\u003cli\u003e Thorough introductions to drug disposition, pharmacokinetics, and pharmacokinetic modeling\u003c\/li\u003e \u003cli\u003e In-depth treatments of the kinetics of drug elimination and the relationship between concentration and effect, including PK–PD modeling\u003c\/li\u003e \u003cli\u003e Comprehensive discussions of predictive pharmacokinetics and the disposition of biological molecules, including peptides and monoclonal antibodies\u003c\/li\u003e \u003cli\u003e Detailed examinations of the effects of sex, pregnancy, age, and disease, as well as drug monitoring in therapeutics and the use of AI in drug development and treatment\u003c\/li\u003e\n\u003c\/ul\u003e \u003cp\u003ePerfect for professionals and researchers working with the scientific aspects of drug disposition in human and veterinary medicine, toxicology, and pharmacology. \u003ci\u003eDrug Disposition and Pharmacokinetics\u003c\/i\u003e will earn a place in the libraries of students of senior-level courses in pharmacy.\u003c\/p\u003e","brand":"Wiley","offers":[{"title":"Default Title","offer_id":47989088092389,"sku":"NP9781119588436","price":190.0,"currency_code":"USD","in_stock":false}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/1842\/7735\/files\/9781119588436.jpg?v=1761782745","url":"https:\/\/k12savings.com\/es\/products\/drug-disposition-and-pharmacokinetics-isbn-9781119588436","provider":"K12savings","version":"1.0","type":"link"}