{"product_id":"dielectrophoresis-isbn-9781118671450","title":"Dielectrophoresis","description":"\u003cp\u003e\u003cb\u003eComprehensive coverage of the  basic theoretical concepts and applications of dielectrophoresis from a world-renowned expert.\u003c\/b\u003e\u003c\/p\u003e \u003cul\u003e \u003cli\u003eFeatures hot application topics including: Diagnostics, Cell-based Drug Discovery, Sensors for Biomedical Applications, Characterisation and Sorting of Stem Cells, Separation of Cancer Cells from Blood and Environmental Monitoring\u003c\/li\u003e \u003cli\u003eFocuses on those aspects of the theory and practice of dielectrophoresis concerned with characterizing and manipulating cells and other bioparticles such as bacteria, viruses, proteins and nucleic acids.\u003c\/li\u003e \u003cli\u003eFeatures the relevant chemical and biological concepts for those working in physics and engineering\u003c\/li\u003e \u003c\/ul\u003e \u003cp\u003eIndex of Worked Examples xi\u003c\/p\u003e \u003cp\u003ePreface xiii\u003c\/p\u003e \u003cp\u003eNomenclature xvii\u003c\/p\u003e \u003cp\u003e\u003cb\u003e1 Placing Dielectrophoresis into Context as a Particle Manipulator 1\u003c\/b\u003e\u003c\/p\u003e \u003cp\u003e1.1 Introduction 1\u003c\/p\u003e \u003cp\u003e1.2 Characteristics of Micro-Scale Physics 2\u003c\/p\u003e \u003cp\u003e1.3 Microfluidic Manipulation and Separation of Particles 3\u003c\/p\u003e \u003cp\u003e1.4 Candidate Forces for Microfluidic Applications 4\u003c\/p\u003e \u003cp\u003e1.5 Combining Dielectrophoresis with other Forces 25\u003c\/p\u003e \u003cp\u003e1.6 Summary 26\u003c\/p\u003e \u003cp\u003e1.7 References 27\u003c\/p\u003e \u003cp\u003e\u003cb\u003e2 How does Dielectrophoresis Differ from Electrophoresis? 31\u003c\/b\u003e\u003c\/p\u003e \u003cp\u003e2.1 Introduction 31\u003c\/p\u003e \u003cp\u003e2.2 Electric Field 32\u003c\/p\u003e \u003cp\u003e2.3 Electrophoresis 33\u003c\/p\u003e \u003cp\u003e2.4 Induced Surface Charge and Dipole Moment 38\u003c\/p\u003e \u003cp\u003e2.5 Dielectrophoresis 40\u003c\/p\u003e \u003cp\u003e2.6 Summary 46\u003c\/p\u003e \u003cp\u003e2.7 References 47\u003c\/p\u003e \u003cp\u003e\u003cb\u003e3 Electric Charges, Fields, Fluxes and Induced Polarization 49\u003c\/b\u003e\u003c\/p\u003e \u003cp\u003e3.1 Introduction 49\u003c\/p\u003e \u003cp\u003e3.2 Charges and Fields 50\u003c\/p\u003e \u003cp\u003e3.3 Gauss’s Law 61\u003c\/p\u003e \u003cp\u003e3.4 Induced Dielectric Polarization 71\u003c\/p\u003e \u003cp\u003e3.5 Capacitance 73\u003c\/p\u003e \u003cp\u003e3.6 DivergenceTheorem and Charge Density Relaxation Time 74\u003c\/p\u003e \u003cp\u003e3.7 Summary 75\u003c\/p\u003e \u003cp\u003e3.8 References 76\u003c\/p\u003e \u003cp\u003e\u003cb\u003e4 Electrical Potential Energy and Electric Potential 77\u003c\/b\u003e\u003c\/p\u003e \u003cp\u003e4.1 Introduction 77\u003c\/p\u003e \u003cp\u003e4.2 Electrical Potential Energy 77\u003c\/p\u003e \u003cp\u003e4.3 Electrical Potential 81\u003c\/p\u003e \u003cp\u003e4.4 Electrostatic Field Energy 87\u003c\/p\u003e \u003cp\u003e4.5 Summary 89\u003c\/p\u003e \u003cp\u003e4.6 References 91\u003c\/p\u003e \u003cp\u003e\u003cb\u003e5 Potential Gradient, Field and Field Gradient; Image Charges and Boundaries 93\u003c\/b\u003e\u003c\/p\u003e \u003cp\u003e5.1 Introduction 93\u003c\/p\u003e \u003cp\u003e5.2 Potential Gradient and Electrical Field 93\u003c\/p\u003e \u003cp\u003e5.3 Applying Laplace’s Equation 96\u003c\/p\u003e \u003cp\u003e5.4 Method of Image Charges 110\u003c\/p\u003e \u003cp\u003e5.5 Electric Field Gradient 112\u003c\/p\u003e \u003cp\u003e5.6 Electrical Conditions at Dielectric Boundaries 114\u003c\/p\u003e \u003cp\u003e5.7 Summary 116\u003c\/p\u003e \u003cp\u003e5.8 References 117\u003c\/p\u003e \u003cp\u003e\u003cb\u003e6 The Clausius–Mossotti Factor 119\u003c\/b\u003e\u003c\/p\u003e \u003cp\u003e6.1 Introduction 119\u003c\/p\u003e \u003cp\u003e6.2 Development of the Clausius–Mossotti–Lorentz Relation 121\u003c\/p\u003e \u003cp\u003e6.3 Refinements of the Clausius–Mossotti–Lorentz Relation 131\u003c\/p\u003e \u003cp\u003e6.4 The Complex Clausius–Mossotti Factor 134\u003c\/p\u003e \u003cp\u003e6.5 Summary 141\u003c\/p\u003e \u003cp\u003e6.6 References 143\u003c\/p\u003e \u003cp\u003e\u003cb\u003e7 Dielectric Polarization 145\u003c\/b\u003e\u003c\/p\u003e \u003cp\u003e7.1 Introduction 145\u003c\/p\u003e \u003cp\u003e7.2 Electrical Polarization at the Atomic and Molecular Levels 145\u003c\/p\u003e \u003cp\u003e7.3 Dipole Relaxation and Energy Loss 153\u003c\/p\u003e \u003cp\u003e7.4 Interfacial Polarization 159\u003c\/p\u003e \u003cp\u003e7.5 Summary 164\u003c\/p\u003e \u003cp\u003e7.6 References 165\u003c\/p\u003e \u003cp\u003e\u003cb\u003e8 Dielectric Properties ofWater, Electrolytes, Sugars, Amino Acids, Proteins and Nucleic Acids 167\u003c\/b\u003e\u003c\/p\u003e \u003cp\u003e8.1 Introduction 167\u003c\/p\u003e \u003cp\u003e8.2 Water 167\u003c\/p\u003e \u003cp\u003e8.3 Electrolyte Solutions 172\u003c\/p\u003e \u003cp\u003e8.4 Amino Acids and Proteins in Solution 179\u003c\/p\u003e \u003cp\u003e8.5 Nucleic Acids 194\u003c\/p\u003e \u003cp\u003e8.6 Summary 204\u003c\/p\u003e \u003cp\u003e8.7 References 206\u003c\/p\u003e \u003cp\u003e\u003cb\u003e9 Dielectric Properties of Cells 213\u003c\/b\u003e\u003c\/p\u003e \u003cp\u003e9.1 Introduction 213\u003c\/p\u003e \u003cp\u003e9.2 Cells: A Basic Description 213\u003c\/p\u003e \u003cp\u003e9.3 Electrical Properties of Cells 214\u003c\/p\u003e \u003cp\u003e9.4 Modelling the Dielectric Properties of Cells 222\u003c\/p\u003e \u003cp\u003e9.5 Effect of Cell Surface Charge on Maxwell–Wagner Relaxation 233\u003c\/p\u003e \u003cp\u003e9.6 Dielectric Properties of Bacteria 236\u003c\/p\u003e \u003cp\u003e9.7 Summary 239\u003c\/p\u003e \u003cp\u003e9.8 References 241\u003c\/p\u003e \u003cp\u003e\u003cb\u003e10 Dielectrophoresis: Theoretical and Practical Considerations 245\u003c\/b\u003e\u003c\/p\u003e \u003cp\u003e10.1 Introduction 245\u003c\/p\u003e \u003cp\u003e10.2 Inherent Approximations in the DEP Force Equation 245\u003c\/p\u003e \u003cp\u003e10.3 Refinements of the DEP Force Equation 249\u003c\/p\u003e \u003cp\u003e10.4 Electrodes: Fabrication, Materials and Modelling 281\u003c\/p\u003e \u003cp\u003e10.5 The Second (High-Frequency) DEP Crossover Frequency (fxo2) 296\u003c\/p\u003e \u003cp\u003e10.6 Summary 298\u003c\/p\u003e \u003cp\u003e10.7 References 300\u003c\/p\u003e \u003cp\u003e\u003cb\u003e11 Dielectrophoretic Studies of Bioparticles 309\u003c\/b\u003e\u003c\/p\u003e \u003cp\u003e11.1 Introduction 309\u003c\/p\u003e \u003cp\u003e11.2 DEP Characterization and Separation of Live and Dead Cells 309\u003c\/p\u003e \u003cp\u003e11.3 Mammalian Cells 332\u003c\/p\u003e \u003cp\u003e11.4 Bacteria 345\u003c\/p\u003e \u003cp\u003e11.5 Other Cell Types (Plant, Algae, Oocytes, Oocysts) andWorms 347\u003c\/p\u003e \u003cp\u003e11.6 Virions 351\u003c\/p\u003e \u003cp\u003e11.7 Nucleic Acids and Proteins 356\u003c\/p\u003e \u003cp\u003e11.8 Summary 369\u003c\/p\u003e \u003cp\u003e11.9 References 370\u003c\/p\u003e \u003cp\u003e\u003cb\u003e12 Microfluidic Concepts of Relevance to Dielectrophoresis 381\u003c\/b\u003e\u003c\/p\u003e \u003cp\u003e12.1 Introduction 381\u003c\/p\u003e \u003cp\u003e12.2 Gases and Liquids 381\u003c\/p\u003e \u003cp\u003e12.3 Fluids Treated as a Continuum 384\u003c\/p\u003e \u003cp\u003e12.4 Basic Fluid Statics and Fluid Dynamics 385\u003c\/p\u003e \u003cp\u003e12.5 Navier–Stokes Equations 392\u003c\/p\u003e \u003cp\u003e12.6 Diffusion 394\u003c\/p\u003e \u003cp\u003e12.7 Ionic (Electrical) Double Layer 397\u003c\/p\u003e \u003cp\u003e12.8 Electro-osmosis 400\u003c\/p\u003e \u003cp\u003e12.9 Summary 403\u003c\/p\u003e \u003cp\u003e12.10 References 404\u003c\/p\u003e \u003cp\u003eAppendices 405\u003c\/p\u003e \u003cp\u003eA Values of Fundamental Physical Constants 405\u003c\/p\u003e \u003cp\u003eB SIPrefixes 405\u003c\/p\u003e \u003cp\u003eC The Base Quantities in the SI System of Units 405\u003c\/p\u003e \u003cp\u003eD Derived Physical Quantities, their Defining Equation or Law and Dimensions 405\u003c\/p\u003e \u003cp\u003eE Diffusion Coefficients for Molecules and Ions inWater at 298 K 406\u003c\/p\u003e \u003cp\u003eF Diffusion Coefficients for Bio-Particles inWater at 293 K 406\u003c\/p\u003e \u003cp\u003eG Viscosity and Surface Tension Values for Liquids at 293 K 406\u003c\/p\u003e \u003cp\u003eH Activity Coefficients for Common Compounds that Dissociate into Ions in Solution 406\u003c\/p\u003e \u003cp\u003eI Electrical Mobility of Ions at 25 ◦C in Dilute Aqueous Solution 406\u003c\/p\u003e \u003cp\u003eJ Buffering Systems and their pH Buffering Range 406\u003c\/p\u003e \u003cp\u003eK Composition of 1 μL of Human Blood 407\u003c\/p\u003e \u003cp\u003eL Blood Cells, Platelets and Some Pathogenic Bioparticles 407\u003c\/p\u003e \u003cp\u003eAuthor Index 411\u003c\/p\u003e \u003cp\u003eSubject Index 423\u003c\/p\u003e   \u003cp\u003e\u003cb\u003e Ronald Pethig\u003c\/b\u003e\u003cbr\u003e Emeritus Professor of Bioelectronics, The University of Edinburgh, UK    \u003c\/p\u003e\u003cp\u003e\u003ci\u003eDielectrophoresis: Theory, Methodology and Biological Applications\u003c\/i\u003e describes the significant advances in the theory, technology and biomedical applications of dielectrophoresis since Herbert Pohl's seminal monograph of 1978. Taking an interdisciplinary approach, it covers aspects of the theory and practice of dielectrophoresis concerned with characterizing and manipulating cells and other bioparticles such as bacteria, viruses, proteins and nucleic acids. An introductory chapter places dielectrophoresis in context as a particle manipulator, and chapters are included to describe the dielectric properties of bioparticles and microfluidic concepts of relevance.\u003c\/p\u003e \u003cp\u003eApplications described include:\u003c\/p\u003e \u003cul\u003e \u003cli\u003eCharacterisation and Sorting of Stem Cells\u003c\/li\u003e \u003cli\u003eSeparation of Cancer Cells from Blood\u003c\/li\u003e \u003cli\u003eCell-based Drug Discovery\u003c\/li\u003e \u003cli\u003eDiagnostics\u003c\/li\u003e \u003cli\u003eSensors for Biomedical Applications\u003c\/li\u003e \u003cli\u003eEnvironmental Monitoring\u003c\/li\u003e \u003c\/ul\u003e \u003cp\u003eThis is a valuable resource for those studying bioelectronics, BIOMEMS, biophysics, biosensors, lab-on-chip technologies, microfluidics, particle analysis and separation, as well as for researchers working on the fundamentals of dielectrophoresis across a wide range of applications, both biological and non-biological. More formal and quantitative material is shown in text boxes for easy identification, while worked examples throughout the text assist student engagement with theory and practical modelling.\u003c\/p\u003e","brand":"Wiley","offers":[{"title":"Default Title","offer_id":47989061452005,"sku":"NP9781118671450","price":156.95,"currency_code":"USD","in_stock":false}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/1842\/7735\/files\/9781118671450.jpg?v=1761782634","url":"https:\/\/k12savings.com\/es\/products\/dielectrophoresis-isbn-9781118671450","provider":"K12savings","version":"1.0","type":"link"}