{"product_id":"copper-oxygen-chemistry-isbn-9780470528358","title":"Copper-Oxygen Chemistry","description":"\u003cb\u003eCovers the vastly expanding subject of oxidative processes mediated by copper ions within biological systems\u003c\/b\u003e  \u003cp\u003eCopper-mediated biological oxidations offer a broad range of fundamentally important and potentially practical chemical processes that cross many chemical and pharmaceutical disciplines. This newest volume in the \u003ci\u003eWiley Series\u003c\/i\u003e on Reactive Intermediates in Chemistry and Biology is divided into three logical areas within the topic of copper\/oxygen chemistry— biological systems, theory, and bioinorganic models and applications—to explore the biosphere for its highly evolved and thus efficient oxidative transformations in the discovery of new types of interactions between molecular oxygen and copper ion. Featuring a diverse collection of subject matter unified in one complete and comprehensive resource, Copper-Oxygen Chemistry probes the fundamental aspects of copper coordination chemistry, synthetic organic chemistry, and biological chemistry to reveal both the biological and chemical aspects driving the current exciting research efforts behind copper-oxygen chemistry. In addition, Copper-Oxygen Chemistry:\u003c\/p\u003e \u003cul\u003e \u003cli\u003e \u003cp\u003eAddresses the significantly increasing literature on oxygen-atom insertion and carbon-carbon bond-forming reactions as well as enantioselective oxidation chemistries\u003c\/p\u003e \u003c\/li\u003e \u003cli\u003e \u003cp\u003eProgresses from biological systems to spectroscopy and theory, and onward to bioinorganic models and applications\u003c\/p\u003e \u003c\/li\u003e \u003cli\u003e \u003cp\u003eCovers a wide array of reaction types such as insertion and dehydrogenation reactions that utilize the cheap, abundant, and energy-containing O2 molecule\u003c\/p\u003e \u003c\/li\u003e \u003c\/ul\u003e \u003cp\u003eWith thorough coverage by prominent authors and researchers shaping innovations in this growing field, this valuable reference is essential reading for bioinorganic chemists, as well as organic, synthetic, and pharmaceutical chemists in academia and industry.\u003c\/p\u003e  Preface to Series vii  \u003cp\u003eIntroduction ix\u003c\/p\u003e \u003cp\u003eContributors xi\u003c\/p\u003e \u003cp\u003e1 Insights into the Proposed Copper–Oxygen Intermediates that Regulate the Mechanism of Reactions Catalyzed by Dopamine b-Monooxygenase, Peptidylglycine a-Hydroxylating Monooxygenase, and Tyramine b-Monooxygenase 1\u003cbr\u003e \u003ci\u003eRobert L. Osborne and Judith P. Klinman\u003c\/i\u003e\u003c\/p\u003e \u003cp\u003e2 Copper Dioxygenases 23\u003cbr\u003e \u003ci\u003eJozsef Kaizer, Jozsef Sandor Pap, and Gabor Speier\u003c\/i\u003e\u003c\/p\u003e \u003cp\u003e3 Amine Oxidase and Galactose Oxidase 53\u003cbr\u003e \u003ci\u003eDalia Rokhsana, Eric M. Shepard, Doreen E. Brown, and David M. Dooley\u003c\/i\u003e\u003c\/p\u003e \u003cp\u003e4 Energy Conversion and Conservation by Cytochrome Oxidases 107\u003cbr\u003e \u003ci\u003eAngela Paulus and Simon de Vries\u003c\/i\u003e\u003c\/p\u003e \u003cp\u003e5 Multicopper Proteins 131\u003cbr\u003e \u003ci\u003eTakeshi Sakurai and Kunishige Kataoka\u003c\/i\u003e\u003c\/p\u003e \u003cp\u003e6 Structure and Reactivity of Copper–Oxygen Species Revealed by Competitive Oxygen-18 Isotope Effects 169\u003cbr\u003e \u003ci\u003eJustine P. Roth\u003c\/i\u003e\u003c\/p\u003e \u003cp\u003e7 Theoretical Aspects of Dioxygen Activation in Dicopper Enzymes 197\u003cbr\u003e \u003ci\u003eKazunari Yoshizawa\u003c\/i\u003e\u003c\/p\u003e \u003cp\u003e8 Chemical Reactivity of Copper Active-Oxygen Complexes 225\u003cbr\u003e \u003ci\u003eShinobu Itoh\u003c\/i\u003e\u003c\/p\u003e \u003cp\u003e9 Cytochrome c Oxidase and Models 283\u003cbr\u003e \u003ci\u003eZakaria Halime and Kenneth D. Karlin\u003c\/i\u003e\u003c\/p\u003e \u003cp\u003e10 Supramolecular Copper Dioxygen Chemistry 321\u003cbr\u003e \u003ci\u003eJean-Noel Rebilly and Olivia Reinaud\u003c\/i\u003e\u003c\/p\u003e \u003cp\u003e11 Organic Synthetic Methods Using Copper Oxygen Chemistry 361\u003cbr\u003e \u003ci\u003eMarisa C. Kozlowski\u003c\/i\u003e\u003c\/p\u003e \u003cp\u003eIndex 445\u003c\/p\u003e  \u003cb\u003eKenneth D. Karlin\u003c\/b\u003e is Ira Remsen Professor of Chemistry at Johns Hopkins University. His bioinorganic research focuses on coordination chemistry relevant to biological and environmental processes, involving copper or heme (porphyrin-iron) complexes. Dr. Karlin's main approach involves synthetic modeling, i.e., biomimetic chemistry. He is the winner of the prestigious F. Albert Cotton Award in Synthetic Inorganic Chemistry and the Sierra Nevada Distinguished Chemist Award, both awarded in 2009.  \u003cp\u003e\u003cb\u003eShinobu Itoh\u003c\/b\u003e focuses his current research on chemical modeling and application of novel active sites in biological systems. He was formerly an assistant professor at Osaka University, where he worked on the chemistry of coenzyme PQQ and cofactor TTQ as well as model compounds of galactose oxidase. In 1994, he was promoted to associate professor at Osaka University, where he collaborated with Professor Shunichi Fukuzumi in copper-dioxygen chemistry research. In 1999, he moved to Osaka City University as a full professor and started biological studies of dinuclear copper proteins, such as hemocyanin and tyrosinase. He returned to Osaka University in 2008 and further expanded his research interests to the design of artificial non-heme metalloenzymes using genetic engineering.\u003c\/p\u003e  \u003cb\u003eCovers the vastly expanding subject of oxidative processes mediated by copper ions within biological systems\u003c\/b\u003e  \u003cp\u003eCopper-mediated biological oxidations offer a broad range of fundamentally important and potentially practical chemical processes that cross many chemical and pharmaceutical disciplines. This newest volume in the \u003ci\u003eWiley Series\u003c\/i\u003e on Reactive Intermediates in Chemistry and Biology is divided into three logical areas within the topic of copper\/oxygen chemistry— biological systems, theory, and bioinorganic models and applications—to explore the biosphere for its highly evolved and thus efficient oxidative transformations in the discovery of new types of interactions between molecular oxygen and copper ion. Featuring a diverse collection of subject matter unified in one complete and comprehensive resource, Copper-Oxygen Chemistry probes the fundamental aspects of copper coordination chemistry, synthetic organic chemistry, and biological chemistry to reveal both the biological and chemical aspects driving the current exciting research efforts behind copper-oxygen chemistry. In addition, Copper-Oxygen Chemistry:\u003c\/p\u003e \u003cul\u003e \u003cli\u003e \u003cp\u003eAddresses the significantly increasing literature on oxygen-atom insertion and carbon-carbon bond-forming reactions as well as enantioselective oxidation chemistries\u003c\/p\u003e \u003c\/li\u003e \u003cli\u003e \u003cp\u003eProgresses from biological systems to spectroscopy and theory, and onward to bioinorganic models and applications\u003c\/p\u003e \u003c\/li\u003e \u003cli\u003e \u003cp\u003eCovers a wide array of reaction types such as insertion and dehydrogenation reactions that utilize the cheap, abundant, and energy-containing O2 molecule\u003c\/p\u003e \u003c\/li\u003e \u003c\/ul\u003e \u003cp\u003eWith thorough coverage by prominent authors and researchers shaping innovations in this growing field, this valuable reference is essential reading for bioinorganic chemists, as well as organic, synthetic, and pharmaceutical chemists in academia and industry.\u003c\/p\u003e","brand":"Wiley","offers":[{"title":"Default Title","offer_id":47988991820005,"sku":"NP9780470528358","price":174.95,"currency_code":"USD","in_stock":false}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/1842\/7735\/files\/9780470528358.jpg?v=1761782343","url":"https:\/\/k12savings.com\/es\/products\/copper-oxygen-chemistry-isbn-9780470528358","provider":"K12savings","version":"1.0","type":"link"}