{"product_id":"chronic-obstructive-pulmonary-disease-isbn-9780471494379","title":"Chronic Obstructive Pulmonary Disease","description":"Chronic obstructive pulmonary disease (COPD) is the most common respiratory disorder of adults in the developed world and is the fourth main cause of death in the USA. It is also associated with high morbidity, and poses an enormous burden of suffering and expense. Despite this, the disease has received little attention compared with other respiratory conditions such as asthma and lung cancer.\u003cbr\u003e \u003cbr\u003e Current treatment can offer some marginal symptomatic relief but does not address the underlying disease process. Indeed, smoking cessation is the only intervention known to alter the rate of disease progression. There is clearly great need, and potential, for the development of superior therapies for symptomatic relief and disease modification. This book brings together leading researchers and physicians to discuss the most recent advances in our understanding of COPD, and draws together basic and clinical aspects relevant to the topic. Coverage includes the basic pathology, current and potential therapies, and detailed consideration of the major theories for the pathogenesis of COPD.Bei chronisch-obstruktiven Lungenerkrankungen, auch COPD genannt, handelt es sich um eine fortschreitende Strömungsbehinderung in den Luftwegen. COPD deckt ein ganzes Spektrum von häufig vorkommenden Atemwegserkrankungen ab, die unbehandelt tödlich verlaufen. Im Vergleich zu anderen Atemwegserkrankungen wie z.B. Asthma und Lungenkrebs, wurde der COPD bislang nur wenig Aufmerksamkeit geschenkt. Die gegenwärtigen Behandlungsmöglichkeiten bieten zwar eine gewisse symptomatische Erleichterung, aber zielen nicht auf die Ursachen der Erkrankung. Deshalb steht die Entwicklung von besseren Therapien zur symptomatischen Erleichterung und zur Veränderung des Krankheitsbildes an oberster Stelle. Dieser Band analysiert und diskutiert die jüngsten Fortschritte bei der Erforschung der COPD und erläutert grundlegende und klinische Aspekte. Darüber hinaus gibt er einen Überblick über vielversprechende neue Forschungsansätze und bietet damit eine unverzichtbare Lektüre für jeden Fachmann auf diesem Gebiet. Overview of the pathology\/pathogenesis\u003cbr\u003e Overview of current therapies\u003cbr\u003e Genetics\u003cbr\u003e Mucus hypersecretion in COPD\u003cbr\u003e Mechanisms of exacerbation\u003cbr\u003e Epithelial and mesenchymal cells\u003cbr\u003e Macrophage control of inflammation: negative pathways of regulation of inflammatory cytokines\u003cbr\u003e Neutrophils\u003cbr\u003e Lymphocytes\u003cbr\u003e Oxidants\/antioxidants\u003cbr\u003e Proteases and anti-proteases -\u003cbr\u003e I\u003cbr\u003e Proteases and anti-proteases -\u003cbr\u003e II\u003cbr\u003e Alveolus formation: critical period, plasticity and retinoid regulation\u003cbr\u003e Systemic effects of COPD\u003cbr\u003e Potential novel therapies for COPD  \u003cp\u003e\"The panel of speakers included some of the most distinguished scientists and physicians working in the field of COPD.\" (\u003cem\u003eBiochemie,\u003c\/em\u003e No. 83, 2001)  \u003c\/p\u003e\u003cp\u003e\u003cb\u003eDerek J. Chadwick\u003c\/b\u003e and \u003cb\u003eJamie A. Goode\u003c\/b\u003e are editors for \u003ci\u003eChronic Obstructive Pulmonary Disease: Pathogenesis to Treatment\u003c\/i\u003e and other scientific titles.\u003c\/p\u003e Chronic obstructive pulmonary disease (COPD) is the most common respiratory disorder of adults in the developed world and is the fourth main cause of death in the USA. It is also associated with high morbidity, and poses an enormous burden of suffering and expense. Despite this, the disease has received little attention compared with other respiratory conditions such as asthma and lung cancer.\u003cbr\u003e \u003cbr\u003e Current treatment can offer some marginal symptomatic relief but does not address the underlying disease process. Indeed, smoking cessation is the only intervention known to alter the rate of disease progression. There is clearly great need, and potential, for the development of superior therapies for symptomatic relief and disease modification. This book brings together leading researchers and physicians to discuss the most recent advances in our understanding of COPD, and draws together basic and clinical aspects relevant to the topic. Coverage includes the basic pathology, current and potential therapies, and detailed consideration of the major theories for the pathogenesis of COPD.","brand":"Wiley","offers":[{"title":"Default Title","offer_id":47988920746213,"sku":"NP9780471494379","price":203.95,"currency_code":"USD","in_stock":false}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/1842\/7735\/files\/9780471494379.jpg?v=1761782056","url":"https:\/\/k12savings.com\/es\/products\/chronic-obstructive-pulmonary-disease-isbn-9780471494379","provider":"K12savings","version":"1.0","type":"link"}