{"product_id":"catalytic-oxidation-reagents-isbn-9781119953272","title":"Catalytic Oxidation Reagents","description":"\u003cp\u003eThe Handbook is part of the Handbook of Reagents for Organic Chemistry series, aiming at collecting articles on a particular theme that individual researchers in academia or industry can use on a daily basis. \u003c\/p\u003e \u003cp\u003eThe Handbook starts with a section discussing the most important aspects of heteroarene functionalization. The introduction is followed by the alphabetical listing of the most relevant reagents drawn from the EROS database. The Editor, André Charette from the University of Montreal, has selected 120 reagent descriptions, many of them updated with heteroarene-specific reactions for this Handbook. Following the standard format for EROS, each article contains an overview of the synthesis and physical properties of the reagents or catalyst, conditions for its storage, and purification methods.\u003c\/p\u003e \u003cp\u003eGiven the importance of heteroarenes in biology and especially in medicinal chemistry, a Handbook that focuses exclusively on heteroarene functionalization has been long overdue. This Handbook will have a broad appeal to many individuals engaged in the area of medicinal chemistry, fine chemical synthesis and industrial-scale chemistry.\u003c\/p\u003e \u003cp\u003e\u003cb\u003eKey features:\u003c\/b\u003e\u003c\/p\u003e \u003cul\u003e \u003cli\u003eBuilds on the success of the previously published Handbooks of Reagents for Organic Synthesis\u003c\/li\u003e \u003cli\u003eCompares the numerous new C-H functionalization reactions that have been developed in the past decade\u003c\/li\u003e \u003cli\u003eHeteroarene functionalization is widely used in the development of pharmaceuticals and other bioactive compounds\u003c\/li\u003e \u003cli\u003eContains listings of secondary reagents for which more information is available in the online edition\u003c\/li\u003e \u003c\/ul\u003e  \u003cp\u003ePreface xi\u003cbr\u003e \u003cbr\u003e Introduction xiii\u003cbr\u003e \u003cbr\u003e Terminal Oxidants Finder xv\u003cbr\u003e \u003cbr\u003e Oxidation Catalyst Finder xix\u003cbr\u003e \u003cbr\u003e Recent Review Articles and Monographs xxv\u003cbr\u003e \u003cbr\u003e Short Note on InChIs and InChIKeys xxvii\u003cbr\u003e \u003cbr\u003e 4-Acetamido-2,2,6,6-tetramethyl-1-piperidinyloxyl 1\u003cbr\u003e \u003cbr\u003e 4-Acetylamino-2,2,6,6-tetramethylpiperidine-1-oxoammonium Tetrafluoroborate 2\u003cbr\u003e \u003cbr\u003e Bathocuproine 15\u003cbr\u003e \u003cbr\u003e Bathophenanthroline 17\u003cbr\u003e \u003cbr\u003e Benzenecarboperoxoic acid, 1, 1-dimethylethyl Ester 20\u003cbr\u003e \u003cbr\u003e 1,2-Benziodoxol-3(1H)-one, 1-Hydroxy, 1-Oxide, IBX 32\u003cbr\u003e \u003cbr\u003e 1,2-Benziodoxol-3(1H)-one, 1-Hydroxy, 1-Oxide, stabilized (stabilized IBX) 44 1,4-Benzoquinone 49\u003cbr\u003e \u003cbr\u003e cis-4-Benzyloxy-α,α-bis-(3,5-dimethylphenyl)-Lprolinol (2S,4R)- 52\u003cbr\u003e \u003cbr\u003e 2,2_-Bipyrrolidines, (2S,2_S) and (2R,2_R) 54\u003cbr\u003e \u003cbr\u003e 2-[Bis-[3,5-bis(trifluoromethyl)Phenyl] [(trimethylsilyl)oxy]Methyl]Pyrrolidine 57\u003cbr\u003e \u003cbr\u003e 2,2-Bis[2-[4(S)-tert-butyl-1,3-oxazolinyl]]propane 59\u003cbr\u003e \u003cbr\u003e Bis[[(1R,1__R)-3,3__-[(1R,2R)-1,2-cyclohexanediylbis [(nitrilo-κN)methylidyne]]bis[2_-phenyl[1,1_-\u003cbr\u003e binaphthalen]-2-olato-κO]](2-)]di-μ-oxodi-titanium and Bis[[(1S,1__S)-3,3__-[(1S,2S)-1,2- cyclohexanediylbis[(nitrilo-κN)methylidyne]]bis [2_-phenyl[1,1_-binaphthalen]-2-olato-κO]](2-)]di- μ-oxodi-titanium 66\u003cbr\u003e \u003cbr\u003e Bis(2,2-dimethylpropanoato - κ-O)phenyl-iodine 69\u003cbr\u003e \u003cbr\u003e Bis(1-methyl-1-phenylethyl) Peroxide 77\u003cbr\u003e \u003cbr\u003e 1,2-Bis(phenylsulfinyl)ethane 79\u003cbr\u003e \u003cbr\u003e N,N_-Bis(2,4,6-trimethylphenyl)imidazol-2-ylidene Palladium(I) Allyl Chloride 82\u003cbr\u003e \u003cbr\u003e Bis(trimethylsilyl) Peroxide 87\u003cbr\u003e \u003cbr\u003e Bromamine-T 91\u003cbr\u003e \u003cbr\u003e N-tert-Butyl-N-chlorocyanamide 94\u003cbr\u003e \u003cbr\u003e tert-Butyl Hydroperoxide 96\u003cbr\u003e \u003cbr\u003e tert-Butyl Hypochlorite 126\u003cbr\u003e \u003cbr\u003e tert-Butyl Peracetate 132\u003cbr\u003e \u003cbr\u003e Calcium Hypochlorite 137\u003cbr\u003e \u003cbr\u003e Chloramine-T 142\u003cbr\u003e \u003cbr\u003e Chlorobenzene 150\u003cbr\u003e \u003cbr\u003e Chloro[N,N_-ethylenebis(salicylideneaminato)] manganese 152\u003cbr\u003e \u003cbr\u003e Chromium(VI) Oxide 157\u003cbr\u003e \u003cbr\u003e Chromyl Acetate 163\u003cbr\u003e \u003cbr\u003e Cobalt, [5,10,15,20-tetraphenyl-21H,23Hporphinato( 2−)-κN 21,κN 22,κN 23,κN 24]- 167\u003cbr\u003e \u003cbr\u003e Cumyl Hydroperoxide 171\u003cbr\u003e \u003cbr\u003e N,N_-(1R,2R)-1,2-Cyclohexanediylbis- [N-hydroxy-α-phenybenzeneacetamide] 179\u003cbr\u003e \u003cbr\u003e 1,5-Diaza-cis-decalin 183\u003cbr\u003e \u003cbr\u003e N,N-Dibromobenzenesulfonamide and N,N-Dibromo-p-toluenesulfonamide 188\u003cbr\u003e \u003cbr\u003e Di-μ-chlorobis(1,5-cyclooctadiene)diiridium(I) 195\u003cbr\u003e \u003cbr\u003e Di-μ-chlorodichlorobis[(1,2,3,4,5-η)-1,2,-3,4,5- pentamethyl-2,4-cyclopentadien-1-yl]diiridium 202\u003cbr\u003e \u003cbr\u003e (R)-2,10-Dichloro-5H-dinaphtho[2,1-g: 1,2-i][1,5]dioxacycloundecin-3,6,9(7h)-trione 210\u003cbr\u003e \u003cbr\u003e Dichloro(ethoxy)oxovanadium(V) 213\u003cbr\u003e \u003cbr\u003e 1,1_-Difluoro-2,2_-bipyridinium Bis-(tetrafluoroborate) 217\u003cbr\u003e \u003cbr\u003e 1,2:4,5-Di-O-isopropylidene-β-d-erythro-hexo-2,3- diulo-2,6-pyranose 221\u003cbr\u003e \u003cbr\u003e Di-μ-methoxobis(1,5-cyclooctadiene)diiridium(I) 224\u003cbr\u003e \u003cbr\u003e Dimethyldioxirane 228\u003cbr\u003e \u003cbr\u003e (S,S)-2,2_-(Dimethylmethylene)bis(4-tert-butyl-2- oxazoline) and (R,R)-2,2_-(Dimethylmethylene)bis- (4-tert-butyl- 2-oxazoline) 234\u003cbr\u003e \u003cbr\u003e Dispiro[2H-pyran-2,4_-[4H-5,6,8b]triazaacenaphthylene- 7_(5_H),2__-[2H]pyran], 1_,2_,2_a,3,3_,3__,4,4__,5,5__,\u003cbr\u003e 6,6__,8_,8_a-tetradecahydro-1_,2_-dimethoxy-6,6__- dimethyl-, monohydrochloride, (1_S,2R,2_S,2__R, 2_aS,6S,6__S,8_aS)- 257\u003cbr\u003e \u003cbr\u003e N-fluoro-N-(phenylsulfonyl)-benzenesulfonamide 259\u003cbr\u003e \u003cbr\u003e N-Fluoropyridinium Tetrafluoroborate 270\u003cbr\u003e \u003cbr\u003e N-Fluoropyridinium Triflate 272\u003cbr\u003e \u003cbr\u003e 1-Fluoro-2,4,6-trimethylpyridinium Tetrafluoroborate 274\u003cbr\u003e \u003cbr\u003e 1-Fluoro-2,4,6-trimethylpyridinium Trifluoromethanesulfonate 278\u003cbr\u003e \u003cbr\u003e Hydrogen Peroxide 281\u003cbr\u003e \u003cbr\u003e Hydrogen Peroxide–Urea 295\u003cbr\u003e \u003cbr\u003e N-Hydroxyphthalimide 307\u003cbr\u003e \u003cbr\u003e Iodine 317\u003cbr\u003e \u003cbr\u003e 2-Iodobenzenesulfonic Acid 332\u003cbr\u003e \u003cbr\u003e Iodosylbenzene 338\u003cbr\u003e \u003cbr\u003e Iridium, [N-[(1R,2R)-2-(amino-κN)-cyclohexyl]-4- methylbenzenesulfonamidato-κN]chloro[(1,2,3,4,5-η)-\u003cbr\u003e 1,2,3,4,5-pentamethyl-2,4,- cyclopentadien-1-yl]-; Iridium, [N-[(1R,2R)-2-(amino-κN)- cyclohexyl]-4-\u003cbr\u003e methylbenzenesulfonamidato-κN]chloro[(1,2,3,4,5-η)- 1,2,3,4,5-pentamethyl-2,4,-cyclopentadien-1-yl]-; Iridium, [N-[(1S,2S)-2-(amino-κN)cyclohexyl]-4- methylbenzenesulfonamidato-κN]-chloro [(1,2,3,4,5-η)-1,2,3,4,5-pentamethyl-2,4,-\u003cbr\u003e cyclopentadien-1-yl]- 354\u003cbr\u003e \u003cbr\u003e Iridium, Dichlorodi-μ-hydrobis[(1,2,3,4,5-η)- 1,2,3,4,5-pentamethyl-2,4-cyclopentadien-1-yl]di- 357\u003cbr\u003e \u003cbr\u003e Iron, Bis(pyridine)bis(2-pyridinecarboxylato-N1,O2) 359\u003cbr\u003e \u003cbr\u003e Lithium Hydroperoxide 363\u003cbr\u003e \u003cbr\u003e Manganese(III) Acetate 367\u003cbr\u003e \u003cbr\u003e Manganese(II), bis(octahydro-1,4,7-trimethyl-1H-1,4,7- triazonine-κN1,κN4,κN7)tri-μ-oxodi-, hexafluorophosphate 375\u003cbr\u003e \u003cbr\u003e Manganese(II) tetraphenylporphyrin 378\u003cbr\u003e \u003cbr\u003e 9-Mesityl-10-methylacridinium Perchlorate 381\u003cbr\u003e \u003cbr\u003e N-Methylmorpholine N-Oxide 384\u003cbr\u003e \u003cbr\u003e (S)-(−)-4-(2-Methylpropyl)-2-(2-pyridyl)-2-oxazoline 388\u003cbr\u003e \u003cbr\u003e Methyl(trifluoromethyl)dioxirane 390\u003cbr\u003e \u003cbr\u003e Methyltrioxorhenium 396\u003cbr\u003e \u003cbr\u003e Molybdenum Chloride Oxide 407\u003cbr\u003e \u003cbr\u003e Noyori Oxidation (Sodium Tungstate Dihydrate, Hydrogen Peroxide, Methyltri-n-octylammonium Hydrogen Sulfate, Phosphonic Acid) 411\u003cbr\u003e \u003cbr\u003e 3,3_,3α,3α _,4,4_,5,5_-Octahydro-3,3,3_,3_-tetraisopropyl- 6,6_-spirobi-[6H-cyclopent[c]isoxazole] 415\u003cbr\u003e \u003cbr\u003e 4,4,4_,4_,5,5,5_,5_-Octamethyl-2,2_-bi-1,3,2-dioxaborolane 421\u003cbr\u003e \u003cbr\u003e Osmium Tetroxide 433\u003cbr\u003e \u003cbr\u003e μ-Oxo-bis[tetrakis(t-butyl)-phthalocyaninatoiron(III)] 452\u003cbr\u003e \u003cbr\u003e Oxygen 454\u003cbr\u003e \u003cbr\u003e Palladium (II) Sparteine Dichloride 467\u003cbr\u003e \u003cbr\u003e Peracetic Acid 470\u003cbr\u003e \u003cbr\u003e (8α,9R)-(8__ α,9__R)-1,1__-[1,3-Phenylene-bis(methylene)] bis[9-hydroxy-cinchonanium] Dibromide and (9S)-(9__S)-1,1__-[1,3-Phenylene-bis(methylene)] bis[9-hydroxy-cinchonanium]Dibromide 478\u003cbr\u003e \u003cbr\u003e (−)(1S)-1-Phenylethyl Hydroperoxide and (+)(1R)-1-Phenylethyl Hydroperoxide 480\u003cbr\u003e \u003cbr\u003e (8α,9R)-(8__ α,9__R)-9,9__-[1,4-Phthalazinediylbis(oxy)] bis[10,11-dihydro-6_-methoxycinchonan] \u0026amp; (9S)-(9__S)-9,9__-[1,4-Phthalazinediylbis(oxy)] bis[10,11-dihydro-6_-methoxycinchonan] 483\u003cbr\u003e \u003cbr\u003e Picolinic Acid 495\u003cbr\u003e \u003cbr\u003e Polyaniline 498\u003cbr\u003e \u003cbr\u003e Potassium Bromate 502\u003cbr\u003e \u003cbr\u003e Potassium Monoperoxysulfate 506\u003cbr\u003e \u003cbr\u003e 2-Pyrazinecarboxylic Acid 524\u003cbr\u003e \u003cbr\u003e 2,3-Pyrazinedicarboxylic Acid 530\u003cbr\u003e \u003cbr\u003e Pyrrolidine, 3,4-bis(diphenylphosphino)-1- (phenylmethyl)-,(3R,4R) and Pyrrolidine, 3,4-bis(diphenylphosphino)-1-(phenylmethyl)-, (3S,4S) 532\u003cbr\u003e \u003cbr\u003e 2-Pyrrolidinemethanol-α,α-bis(3,5-dimethylphenyl)- (2S); and 2-Pyrrolidine-methanol-α,α-bis(3,5- dimethylphenyl)-(2R) 535\u003cbr\u003e \u003cbr\u003e Rhenium(VII) Oxide 541\u003cbr\u003e \u003cbr\u003e [RuCl2(p-cymene)2]2 546\u003cbr\u003e \u003cbr\u003e Ruthenium(III) Chloride 549\u003cbr\u003e \u003cbr\u003e Ruthenium Complex of N,N_,N_-Trimethyl-1,4,7-triazacyclononane and Ruthenium Complex of cis-Diaquabis\u003cbr\u003e (6,6_-Dichloro-2,2_-bipyridine) 561\u003cbr\u003e \u003cbr\u003e Ruthenium Dodecacarbonyltri Triangulo 565\u003cbr\u003e \u003cbr\u003e Ruthenium Hydroxide 568\u003cbr\u003e \u003cbr\u003e Selenium(IV) Oxide 575\u003cbr\u003e \u003cbr\u003e Sodium Bromate 583\u003cbr\u003e \u003cbr\u003e Sodium Hypochlorite 587\u003cbr\u003e \u003cbr\u003e Sodium Hypochlorite–N,N_-Bis(3,5-di-tertbutylsalicylidene)- 1,2-cyclohexanediaminomanganese( III) Chloride 600\u003cbr\u003e \u003cbr\u003e Spiro[6H-1,3-dioxolo[4,5-c]pyran-6,5_-oxazolidine]-3_- carboxylic acid, tetrahydro-2,2-dimethyl-2_,7- dioxo-,2-methyl-2-propyl ester, (3aR, 5_S, 7aR)- 604\u003cbr\u003e \u003cbr\u003e Tetrabutylammonium Bis(pyrazinecarboxylato)- dioxo-vanadium(V) 609\u003cbr\u003e \u003cbr\u003e Tetrabutylammonium Dodecatungstophosphate 611\u003cbr\u003e \u003cbr\u003e Tetrabutylammonium Peroxydisulfate 615\u003cbr\u003e \u003cbr\u003e 5,6,7,8-Tetrafluoro-1-hydroxy-1-oxobenziodoxol- 3(1H)one (Tetrafluoro-IBX) 618\u003cbr\u003e \u003cbr\u003e 2,2,6,6-Tetramethylpiperidin-1-oxyl 620\u003cbr\u003e \u003cbr\u003e Tetra-n-propylammonium Perruthenate 626\u003cbr\u003e \u003cbr\u003e 3,3_,5,5_-Tetra-tert-butyldiphenoquinone 630\u003cbr\u003e \u003cbr\u003e (S)-2-(5-1H-Tetrazolyl)pyrrolidine and (R)-2-(5-1H-Tetrazolyl)pyrrolidine 633\u003cbr\u003e \u003cbr\u003e 4,4_,4__-tri-tert-butyl-2,2_:6_,2__-terpyridine 639\u003cbr\u003e \u003cbr\u003e Trichloroisocyanuric Acid 642\u003cbr\u003e \u003cbr\u003e Trifluoroperacetic Acid 649\u003cbr\u003e \u003cbr\u003e Trimethylamine N-Oxide 659\u003cbr\u003e \u003cbr\u003e Triphenylmethyl Hydroperoxide 667\u003cbr\u003e \u003cbr\u003e Tris(2-pyridylmethyl)amine 670\u003cbr\u003e \u003cbr\u003e Tris[4-(trifluoromethyl)phenyl]phosphine 677\u003cbr\u003e \u003cbr\u003e Vanadium,bis[N-[(1S)-1-(carboxy-κO)ethyl]-N- (hydroxy-κO)-l-alaninato(2-)-κN,κO]- 681\u003cbr\u003e \u003cbr\u003e Vanadyl Bis(acetylacetonate) 684\u003cbr\u003e \u003cbr\u003e List of Contributors 693\u003cbr\u003e \u003cbr\u003e Reagent Formula Index 707\u003cbr\u003e \u003cbr\u003e Subject Index 711\u003c\/p\u003e \u003cp\u003e\u003cb\u003eProfessor Philip L. Fuchs, Department of Chemistry, Purdue University\u003c\/b\u003e\u003cbr\u003ePhilip Fuchs began his career at Purdue in 1973. Since that time, he has graduated an extended family of 55 Ph.D.s. His awards and honors include an Eli Lilly young faculty fellowship (1975), an Alfred P. Sloan fellowship (1977), a Pioneer in Laboratory Robotics award (1986), a Martin teaching award (1991), and being voted by the students as one of Top 10 Teachers in School of Science at Purdue (1991, 1993, 1995, 1996).\u003cbr\u003eFuchs has consulted for Pfizer, and Eli Lilly, served on the editorial board of The Journal of Organic Chemistry, and is currently an executive editor for the \u003ci\u003eElectronic Encyclopedia of Organic Reagents (e-EROS)\u003c\/i\u003e, an online dynamic encyclopedia published by John Wiley \u0026amp; Sons.\u003c\/p\u003e","brand":"Wiley","offers":[{"title":"Default Title","offer_id":47988892860645,"sku":"NP9781119953272","price":197.95,"currency_code":"USD","in_stock":false}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/1842\/7735\/files\/9781119953272.jpg?v=1761781948","url":"https:\/\/k12savings.com\/es\/products\/catalytic-oxidation-reagents-isbn-9781119953272","provider":"K12savings","version":"1.0","type":"link"}