{"product_id":"biostatistical-genetics-and-genetic-epidemiology-isbn-9780471486312","title":"Biostatistical Genetics and Genetic Epidemiology","description":"Human Genetics concerns the study of genetic forces in man. By studying our genetic make-up we are able to understand more about our heritage and evolution. Some of the original, and most significant research in genetics centred around the study of the genetics of complex diseases - genetic epidemiology.\u003cbr\u003e \u003cbr\u003e This is the third in a highly successful series of books based on articles from the Encyclopedia of Biostatistics. This volume will be a timely and comprehensive reference, for a subject that has seen a recent explosion of interest following the completion of the first draft of the Human Genome Mapping Project. The editors have updated the articles from the Human Genetics section of the EoB, have adpated other articles to give them a genetic feel, and have included a number of newly commissioned articles to ensure the work is comprehensive and provides a self-contained reference.\"Human Genetics and Genetic Epidemiology\" ist der 3. Band aus der sehr erfolgreichen Reihe 'Wiley Biostatistics Reference Series', die auf Artikeln der \"Encyclopedia of Biostatistics\" basiert. Dieser Band gibt einen topaktuellen und umfassenden Überblick über ein Forschungsgebiet, das insbesondere im Zuge des Human-Genomprojekts eine regelrechte Explosion an Forschungsaktivitäten erlebt hat. Enthalten sind komplett aktualisierte Artikel aus der \"Encyclopedia of Biostatistics\" sowie über 25% neue Artikel. Mit einem komplexen System an Querverweisen, die das Auffinden der gewünschten Information erheblich erleichtern. Eine interessante Lektüre für Genetiker, Epidemiologen, Biostatistiker und Forscher in diesen Bereichen. Admixture in Human Populations\u003cbr\u003e Admixture Mapping\u003cbr\u003e Adoption Studies\u003cbr\u003e Age-of-Onset Estimation\u003cbr\u003e Akaike's Criteria\u003cbr\u003e Alternative Hypothesis\u003cbr\u003e Anticipation\u003cbr\u003e Ascertainment\u003cbr\u003e Association\u003cbr\u003e Association, Measures of\u003cbr\u003e Assortative Mating\u003cbr\u003e Attributable Risk\u003cbr\u003e Bayes' Theorem\u003cbr\u003e Bias\u003cbr\u003e Bias in Case- Control Studies\u003cbr\u003e Bioinformatics\u003cbr\u003e Blood Groups\u003cbr\u003e Bonferroni Inequalities and Intervals\u003cbr\u003e Bootstrap Method\u003cbr\u003e Candidate Gene\u003cbr\u003e Carcinogenesis Models\u003cbr\u003e Case-Cohort\u003cbr\u003e Case-Control Study\u003cbr\u003e Case-Only Gene Mapping\u003cbr\u003e Causation\u003cbr\u003e Cladistic Analysis\u003cbr\u003e Cohort Studies\u003cbr\u003e Collinearity\u003cbr\u003e Commingling Analysis\u003cbr\u003e Comparative Genomic Hybridization\u003cbr\u003e Complex Diseases\u003cbr\u003e Confidence Intervals and Sets\u003cbr\u003e Confounder\u003cbr\u003e Confounding\u003cbr\u003e Consistent Estimator\u003cbr\u003e Controls\u003cbr\u003e Correlated Binary Data\u003cbr\u003e Correlation\u003cbr\u003e Covariate\u003cbr\u003e Cox Regression Model\u003cbr\u003e Cumulative Incidence\u003cbr\u003e Diagnostics\u003cbr\u003e Discriminant Analysis, Linear\u003cbr\u003e Disease-Marker Association\u003cbr\u003e DNA Sequences\u003cbr\u003e Dummy Variables\u003cbr\u003e Elston-Stewart Algorithm\u003cbr\u003e EM Algorithm\u003cbr\u003e Eugenics\u003cbr\u003e Exclusion Mapping\u003cbr\u003e Expectation\u003cbr\u003e Experiment-Wise Error Rate\u003cbr\u003e Familial Correlations\u003cbr\u003e Family History Validation\u003cbr\u003e Family-Based Association for Quantitative\u003cbr\u003e Traits\u003cbr\u003e Family-Based Case-Control Studies\u003cbr\u003e Fixed Effects\u003cbr\u003e Founder Effect\u003cbr\u003e Frailty\u003cbr\u003e Frequency Matching\u003cbr\u003e Gene\u003cbr\u003e Gene Conversion\u003cbr\u003e Gene Expression Analysis\u003cbr\u003e Gene Frequency Estimation\u003cbr\u003e Gene-Environment Interaction\u003cbr\u003e General Linear Model\u003cbr\u003e Generalized Estimating Equations\u003cbr\u003e Generalized Linear Model\u003cbr\u003e Generalized Maximum Likelihood\u003cbr\u003e Genetic Correlations and Covariances\u003cbr\u003e Genetic Counseling\u003cbr\u003e Genetic Distance\u003cbr\u003e Genetic Epidemiology\u003cbr\u003e Genetic Heterogeneity\u003cbr\u003e Genome-Wide Significance\u003cbr\u003e Genotype\u003cbr\u003e Genotyping and Error-Checking\u003cbr\u003e Goodness of Fit\u003cbr\u003e Haplotype Analysis\u003cbr\u003e Hardy-Weinberg Equilibrium\u003cbr\u003e Heritability\u003cbr\u003e Heterozygosity\u003cbr\u003e Hidden Markov Models\u003cbr\u003e Hierarchical Models\u003cbr\u003e HLA System\u003cbr\u003e Human Genetics, Overview\u003cbr\u003e Human Genome Project\u003cbr\u003e Identity Coefficients\u003cbr\u003e Importance Sampling\u003cbr\u003e Inbreeding\u003cbr\u003e Incidence Rate\u003cbr\u003e Incidence-Prevalence Relationships\u003cbr\u003e Incident Case\u003cbr\u003e Information\u003cbr\u003e Information Matrix\u003cbr\u003e Interaction\u003cbr\u003e Isolated Populations\u003cbr\u003e Kin-Cohort Studies\u003cbr\u003e Kurtosis\u003cbr\u003e Lambda Criterion, Wilks'\u003cbr\u003e Level of a Test \u003cbr\u003e Liability Model\u003cbr\u003e Likelihood\u003cbr\u003e Likelihood Ratio\u003cbr\u003e Likelihood Ratio Tests\u003cbr\u003e Linear Regression, Simple\u003cbr\u003e Linkage Analysis, Model-Based \u003cbr\u003e Linkage Analysis, Model-Free\u003cbr\u003e Linkage Disequilibrium\u003cbr\u003e Linkage Information Content\u003cbr\u003e Logistic Regression, Conditional\u003cbr\u003e Loss of Heterozygosity\u003cbr\u003e Map Functions\u003cbr\u003e Marginal Likelihood\u003cbr\u003e Marginal Models\u003cbr\u003e Markers\u003cbr\u003e Markov Chain Monte Carlo\u003cbr\u003e Markov Chains\u003cbr\u003e Matched Analysis\u003cbr\u003e Matching\u003cbr\u003e Maximum Likelihood\u003cbr\u003e McNemar Test\u003cbr\u003e Mendel's Laws\u003cbr\u003e Meta-analysis\u003cbr\u003e Mixed Model in Segregation Analysis\u003cbr\u003e Molecular Epidemiology\u003cbr\u003e Monte Carlo Methods\u003cbr\u003e Multilocus (Gene �Gene) Interaction\u003cbr\u003e Multiple Comparisons\u003cbr\u003e Multiplicative Model\u003cbr\u003e Multipoint Linkage Analysis\u003cbr\u003e Multivariate Linkage Analysis\u003cbr\u003e Multivariate Normal Distribution\u003cbr\u003e Multivariate Normality, Tests of\u003cbr\u003e Mutation\u003cbr\u003e Neural Networks\u003cbr\u003e Null Hypothesis\u003cbr\u003e Odds Ratio\u003cbr\u003e Ornstein-Uhlenbeck Process\u003cbr\u003e Overmatching\u003cbr\u003e P Value\u003cbr\u003e Parental Effects\u003cbr\u003e Parsimony\u003cbr\u003e Partial Likelihood\u003cbr\u003e Paternity Testing\u003cbr\u003e Path Analysis\u003cbr\u003e Pedigrees, Sequential Sampling\u003cbr\u003e Penetrance\u003cbr\u003e Pharmacogenetics\u003cbr\u003e Polygenic Inheritance\u003cbr\u003e Polymorphism\u003cbr\u003e Polymorphism Information Content\u003cbr\u003e Population Genetics\u003cbr\u003e Population-Based Study\u003cbr\u003e Power Transformations\u003cbr\u003e Prediction\u003cbr\u003e Prevalence\u003cbr\u003e Principal Components Analysis\u003cbr\u003e Profile Likelihood\u003cbr\u003e Protecting Privacy in Genetic Studies\u003cbr\u003e Pseudo-Likelihood\u003cbr\u003e Radiation Hybrid Mapping\u003cbr\u003e Random Effects\u003cbr\u003e Regression\u003cbr\u003e Regressive Models\u003cbr\u003e Relationship Testing\u003cbr\u003e Relative Odds\u003cbr\u003e Relative Risk\u003cbr\u003e Residuals\u003cbr\u003e Response Variable\u003cbr\u003e Risk Ratios\u003cbr\u003e Segregation Analysis, Classical\u003cbr\u003e Segregation Analysis, Complex\u003cbr\u003e Segregation Ratios\u003cbr\u003e Selection Bias\u003cbr\u003e Sensitivity\u003cbr\u003e Sequence Analysis\u003cbr\u003e Sequential Linkage Analysis\u003cbr\u003e Sex Ratio at Birth\u003cbr\u003e Simulated Annealing\u003cbr\u003e Simulation\u003cbr\u003e Skewness\u003cbr\u003e Software for Genetic Epidemiology\u003cbr\u003e Specificity\u003cbr\u003e Statistical Forensics\u003cbr\u003e Stratification\u003cbr\u003e Transformations\u003cbr\u003e Transition Probabilities\u003cbr\u003e Twin Analysis\u003cbr\u003e Twin Concordance\u003cbr\u003e Twin Registers\u003cbr\u003e Two-Phase Sampling\u003cbr\u003e Unbiasedness\u003cbr\u003e Univariate Response\u003cbr\u003e Validity and Generalizability in Epidemiologic Studies\u003cbr\u003e Variance\u003cbr\u003e Variance Component Analysis\u003cbr\u003e X-linkage\u003cbr\u003e Zygosity Determination \"...a highly useful tool for those already engaged in research in biostatistical genetics and genetic epidemiology.\" (American Journal of Physical Anthropology, August 2005)\u003cbr\u003e \u003cbr\u003e \"...an excellent reference guide, especially useful as an introduction to topics where the researcher is not an expert...\" (Statistical Methods in Medical Research, Vol.14, No.1, 2005)\u003cbr\u003e \u003cbr\u003e \"...a very useful addition to the genetic epidemiologist's bookshelf.\" (Journal of the American Statistical Association, June 2004)\u003cbr\u003e \u003cbr\u003e \"...articles were commendably brief and informative...I expect to use this book frequently in the future...\" (Short Book Reviews, 2004)\u003cbr\u003e \u003cbr\u003e \"This wonderfully compiled book will be a great reference book for the genetic statisticians and epidemiologists.\" (Journal of Statistical Computation and Simulation, July 2003)\u003cbr\u003e \u003cbr\u003e \"...the third extraction...from the comprehensive Encyclopedia of Biostatistics...a good value for statisticians with an interest in genetics.\" (Technometrics, Vol. 44, No. 4, November 2002)  \u003cp\u003eDr. Robert C. Elston is a statistical geneticist and distinguished professor emeritus at Case Western Reserve University. He was born in London, England. He is one of the eponyms of the Elston-Stewart algorithm. Jane M. Olson is the editor of Biostatistical Genetics and Genetic Epidemiology, published by Wiley.\u003c\/p\u003e","brand":"Wiley","offers":[{"title":"Default Title","offer_id":47988842234085,"sku":"NP9780471486312","price":766.95,"currency_code":"USD","in_stock":false}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/1842\/7735\/files\/9780471486312.jpg?v=1761781736","url":"https:\/\/k12savings.com\/es\/products\/biostatistical-genetics-and-genetic-epidemiology-isbn-9780471486312","provider":"K12savings","version":"1.0","type":"link"}