{"product_id":"biomineralization-isbn-9780470092095","title":"Biomineralization","description":"This title takes an interdisciplinary approach to the central role of solubility in pathological biomineralisation, ranging from traditional thermodynamics and kinetics to unusual concepts such as the PILP process. The scientific background and expertise of the contributors, ranges accordingly from solubility modelling and database development, renal stone and bone implant research, Mössbauer spectroscopy and structural chemistry to biochemistry and crystallisation. The chapters all have a quantitative, physico-chemical component rather than giving purely phenomenological descriptions. The contributors deal with aspects and concepts that have not previously been common in the study of pathological biomineralisation processes.  \u003cb\u003eList of Contributors.\u003c\/b\u003e  \u003cp\u003e\u003cb\u003eForeword.\u003c\/b\u003e\u003c\/p\u003e \u003cp\u003e\u003cb\u003ePreface.\u003c\/b\u003e\u003c\/p\u003e \u003cp\u003e\u003cb\u003eAcknowledgements.\u003c\/b\u003e\u003c\/p\u003e \u003cp\u003e\u003cb\u003e1 Solubility Phenomena Related to Normal and Pathological Biomineralization Processes\u003c\/b\u003e (\u003ci\u003eErich Königsberger and LanChi Königsberger\u003c\/i\u003e).\u003c\/p\u003e \u003cp\u003e1.1 Introduction.\u003c\/p\u003e \u003cp\u003e1.2 Experimental Methods.\u003c\/p\u003e \u003cp\u003e1.2.1 Solubility Measurements.\u003c\/p\u003e \u003cp\u003e1.2.2 Solution Calorimetry.\u003c\/p\u003e \u003cp\u003e1.2.3 Kinetic Measurements.\u003c\/p\u003e \u003cp\u003e1.3 Thermodynamic Modeling of Biological Systems.\u003c\/p\u003e \u003cp\u003e1.3.1 Introduction.\u003c\/p\u003e \u003cp\u003e1.3.2 Chemical Speciation, Blood Plasma Models and Chelation Therapy.\u003c\/p\u003e \u003cp\u003e1.3.3 Metal Solubility and Toxicity.\u003c\/p\u003e \u003cp\u003e1.3.4 Urine Models.\u003c\/p\u003e \u003cp\u003e1.3.5 Modeling Pancreatic and Biliary Stone Formation.\u003c\/p\u003e \u003cp\u003e1.4 New Insights in Solubility Phenomena Relevant to Biomineralization.\u003c\/p\u003e \u003cp\u003e1.4.1 Solubility of Nanomaterials and Biological Demineralization.\u003c\/p\u003e \u003cp\u003e1.4.2 New Mechanisms of Biomineralization.\u003c\/p\u003e \u003cp\u003eReferences.\u003c\/p\u003e \u003cp\u003e\u003cb\u003e2 Mechanisms of Renal and Salivary Calculi Formation and Development\u003c\/b\u003e (\u003ci\u003eFélix Grases and Antonia Costa-Bauzá\u003c\/i\u003e).\u003c\/p\u003e \u003cp\u003e2.1 Introduction.\u003c\/p\u003e \u003cp\u003e2.1.1 Renal Lithiasis.\u003c\/p\u003e \u003cp\u003e2.1.2 Sialolithiasis.\u003c\/p\u003e \u003cp\u003e2.2 Classification of Renal Calculi and Formation Mechanisms.\u003c\/p\u003e \u003cp\u003e2.2.1 Calcium Oxalate Renal Calculi.\u003c\/p\u003e \u003cp\u003e2.2.2 Phosphate Renal Calculi.\u003c\/p\u003e \u003cp\u003e2.2.3 Calcium Oxalate Dihydrate\/Hydroxyapatite Mixed Calculi.\u003c\/p\u003e \u003cp\u003e2.2.4 Uric Acid Renal Calculi.\u003c\/p\u003e \u003cp\u003e2.2.5 Cystine Renal Calculi.\u003c\/p\u003e \u003cp\u003e2.2.6 Infrequent Renal Calculi.\u003c\/p\u003e \u003cp\u003e2.2.7 General Considerations About Renal Calculi.\u003c\/p\u003e \u003cp\u003e2.3 Mechanisms of Formation of Sialoliths.\u003c\/p\u003e \u003cp\u003eReferences.\u003c\/p\u003e \u003cp\u003e\u003cb\u003e3 Calcium and Magnesium Phosphates: Normal and Pathological Mineralization\u003c\/b\u003e (\u003ci\u003eM. Clara F. Magalhães, Paula A. A. P. Marques and Rui N. Correia\u003c\/i\u003e).\u003c\/p\u003e \u003cp\u003e3.1 Introduction.\u003c\/p\u003e \u003cp\u003e3.2 Stability of Magnesium and Calcium Phosphates.\u003c\/p\u003e \u003cp\u003e3.2.1 Magnesium Phosphates.\u003c\/p\u003e \u003cp\u003e3.2.2 Whitlockite (TCMP).\u003c\/p\u003e \u003cp\u003e3.2.3 Calcium Phosphates.\u003c\/p\u003e \u003cp\u003e3.3 Calcium Diphosphate Dihydrate.\u003c\/p\u003e \u003cp\u003e3.4 Biological and \u003ci\u003ein Vitro\u003c\/i\u003e Occurrences of Calcium and Magnesium Phosphates.\u003c\/p\u003e \u003cp\u003e3.4.1 Normal Calcifications – Bones and Teeth.\u003c\/p\u003e \u003cp\u003e3.4.2 Pathological Calcifications.\u003c\/p\u003e \u003cp\u003e3.4.3 Calcium Phosphate Biomaterials.\u003c\/p\u003e \u003cp\u003eAcknowledgements.\u003c\/p\u003e \u003cp\u003eReferences.\u003c\/p\u003e \u003cp\u003e\u003cb\u003e4 Relevance of a Polymer-Induced Liquid-Precursor (PILP) Mineralization Process to Normal and Pathological Biomineralization\u003c\/b\u003e (\u003ci\u003eFairland F. Amos, Matthew J. Olszta, Saeed R. Khan and Laurie B. Gower\u003c\/i\u003e).\u003c\/p\u003e \u003cp\u003e4.1 Introduction.\u003c\/p\u003e \u003cp\u003e4.1.1 Crystallization Mechanisms.\u003c\/p\u003e \u003cp\u003e4.1.2 \u003ci\u003eIn Vitro\u003c\/i\u003e Models of Biomineralization.\u003c\/p\u003e \u003cp\u003e4.1.3 Influence of Additives on Crystal Nucleation.\u003c\/p\u003e \u003cp\u003e4.1.4 Influence of Additives on Crystal Growth.\u003c\/p\u003e \u003cp\u003e4.2 Bone.\u003c\/p\u003e \u003cp\u003e4.2.1 The Structure of Bone.\u003c\/p\u003e \u003cp\u003e4.2.2 The Properties of Bone.\u003c\/p\u003e \u003cp\u003e4.2.3 The Organic Matrix of Bone.\u003c\/p\u003e \u003cp\u003e4.2.4 The Mineral Phase of Bone.\u003c\/p\u003e \u003cp\u003e4.2.5 Formation of Bone.\u003c\/p\u003e \u003cp\u003e4.2.6 Biomimetic Methods for Mineralizing Collagen.\u003c\/p\u003e \u003cp\u003e4.2.7 Mineral Precursor Phases.\u003c\/p\u003e \u003cp\u003e4.2.8 Concluding Remarks on Bone Formation.\u003c\/p\u003e \u003cp\u003e4.3 Kidney Stones.\u003c\/p\u003e \u003cp\u003e4.3.1 Free vs Fixed Particle Mechanisms.\u003c\/p\u003e \u003cp\u003e4.3.2 The Complex Urinary Environment.\u003c\/p\u003e \u003cp\u003e4.3.3 Mixed Composite Stones with CaP Core.\u003c\/p\u003e \u003cp\u003e4.3.4 Morphological Clues of Crystallization Mechanism.\u003c\/p\u003e \u003cp\u003e4.3.5 Concluding Remarks on Stone Formation.\u003c\/p\u003e \u003cp\u003eReferences.\u003c\/p\u003e \u003cp\u003e\u003cb\u003e5 Pathological Biomineralization of Iron\u003c\/b\u003e (\u003ci\u003eWanida Chua-anusorn and Timothy G. St Pierre\u003c\/i\u003e).\u003c\/p\u003e \u003cp\u003e5.1 Introduction.\u003c\/p\u003e \u003cp\u003e5.1.1 Biogenic Iron Oxides.\u003c\/p\u003e \u003cp\u003e5.1.2 Iron Metabolism.\u003c\/p\u003e \u003cp\u003e5.1.3 Iron Overload.\u003c\/p\u003e \u003cp\u003e5.1.4 Iron Oxide Deposits in Tissues.\u003c\/p\u003e \u003cp\u003e5.1.5 Disease Specific Chemical Speciation of Hemosiderin Iron.\u003c\/p\u003e \u003cp\u003e5.1.6 Transformation of Ferrihydrite to Goethite.\u003c\/p\u003e \u003cp\u003e5.2 Reactivity of Pathological Iron Oxide Deposits.\u003c\/p\u003e \u003cp\u003e5.2.1 Iron Oxide Isolation and Characterization.\u003c\/p\u003e \u003cp\u003e5.2.2 Materials.\u003c\/p\u003e \u003cp\u003e5.2.3 Isolation of the Iron Storage Components from Tissues.\u003c\/p\u003e \u003cp\u003e5.2.4 Methods.\u003c\/p\u003e \u003cp\u003e5.2.5 Results.\u003c\/p\u003e \u003cp\u003e5.2.6 Discussion.\u003c\/p\u003e \u003cp\u003e5.3 Accessibility of Hemosiderin Iron to an Iron Chelator.\u003c\/p\u003e \u003cp\u003e5.3.1 Materials and Methods.\u003c\/p\u003e \u003cp\u003e5.3.2 Results.\u003c\/p\u003e \u003cp\u003e5.3.3 Discussion.\u003c\/p\u003e \u003cp\u003e5.4 Concluding Remarks.\u003c\/p\u003e \u003cp\u003eReferences.\u003c\/p\u003e \u003cp\u003e\u003cb\u003eIndex.\u003c\/b\u003e\u003c\/p\u003e \u003cb\u003eDr E. Königsberger\u003c\/b\u003e and \u003cb\u003eDr L. Königsberger\u003c\/b\u003e (Editors), Department of Chemistry, Division of Science and Engineering, Murdoch University, South Street, Murdoch, WA 6150, Australia  Solubility phenomena are fundamental to living organisms and range from gas solubilities (\u003ci\u003ee.g.\u003c\/i\u003e oxygen in blood) to biomineral formation in body fluids. This book comprises five chapters on various perspectives of normal and pathological biomineralization in humans.  \u003cp\u003eChapter 1 gives an overview of experimental and modeling methods, recommends solubility data for selected stone-forming substances and describes recently discovered, unusual dissolution and crystallization phenomena involving nano-sized biomaterials.\u003c\/p\u003e \u003cp\u003eChapter 2 presents a general classification of renal and salivary calculi based on their formation mechanism.\u003c\/p\u003e \u003cp\u003eChapter 3 reviews the solubilities of calcium and magnesium phosphates and discusses their relevance to normal and pathological mineralization in terms of stability field diagrams.\u003c\/p\u003e \u003cp\u003eChapter 4 proposes a new paradigm for biomineralization - liquid phase precursors - and their possible roles in the formation of bone and kidney stones.\u003c\/p\u003e \u003cp\u003eIn Chapter 5, various aspects of the biomineralization of iron and its relation to iron overload diseases are discussed.\u003c\/p\u003e \u003cp\u003eAimed at chemists interested in solution chemistry, thermodynamics, kinetics, crystallisation, biochemistry, biomineralisation, medicinal chemistry and industrial chemistry, this book is also relevant to doctors and biologists interested in research in urology, nephrology, clinical chemistry and chelation therapy.\u003c\/p\u003e","brand":"Wiley","offers":[{"title":"Default Title","offer_id":47988839842021,"sku":"NP9780470092095","price":287.95,"currency_code":"USD","in_stock":false}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/1842\/7735\/files\/9780470092095.jpg?v=1761781726","url":"https:\/\/k12savings.com\/es\/products\/biomineralization-isbn-9780470092095","provider":"K12savings","version":"1.0","type":"link"}