{"product_id":"aminophosphonic-and-aminophosphinic-acids-isbn-9780471891499","title":"Aminophosphonic and Aminophosphinic Acids","description":"Aminophosphinic and aminoposphonic acids, synthetic analogs to natural amino acids, have attained a position of prominence in research--particularly in research involving the modification of physiological processes in living organisms.Die erste umfassende Abhandlung über Chemie und biologische Aktivität der Aminophosphin- und -phosphonsäuren einschließlich ihrer Derivate (Ester und Peptide)! Der Schwerpunkt liegt auf der anwendungsorientierten agrochemischen und biomedizinischen Forschung, beispielsweise im Hinblick auf die Inhibition von Proteasen. Ausführlich diskutiert wird die enantioselektive Synthese der Verbindungen. Mit vielen spektroskopischen und Strukturdaten. (02\/00)  Naturally Occurring Aminophosphonic and Aminophosphinic Acids (P. Mastalerz \u0026amp; P. Kafarski).\u003cbr\u003e \u003cbr\u003e Synthesis of -Aminoalkanephosphonic and -Aminoalkanephosphinic Acids (P. Kafarski \u0026amp; J. Zo).\u003cbr\u003e \u003cbr\u003e Synthesis of Aminoalkanephosphonic and Aminoalkanephosphinic Acids with the Amino Substituent in Other than the -Position (V. Kukhar).\u003cbr\u003e \u003cbr\u003e -Amino Acid Analogues Bearing Side-Chain C-P Linkages (S. Lall and R. Engel).\u003cbr\u003e \u003cbr\u003e Asymmetric Synthesis of Aminophosphonic and Aminophosphinic Acids (V. Kukhar).\u003cbr\u003e \u003cbr\u003e Synthesis of Phosphono- and Phosphinopeptides (P. Kafarski \u0026amp; B. Lejczak).\u003cbr\u003e \u003cbr\u003e Column Chromatography of Aminophosphonic Acids and Phosphonopeptides (S. Galushko).\u003cbr\u003e \u003cbr\u003e Physical Properties and NMR-Spectroscopic Characterization of Aminophosphonates and Aminophosphinates (G. Hägele).\u003cbr\u003e \u003cbr\u003e Structure and Stability Constants of Metal Complexes in Solution (T. Kiss \u0026amp; I. Lázár).\u003cbr\u003e \u003cbr\u003e X-Ray Crystallographic Studies (N. Choi \u0026amp; M. McPartlin).\u003cbr\u003e \u003cbr\u003e Mass Spectrometry and Gas Chromatography-Mass Spectrometry of Aminoalkanephosphonic Acids (Z. Kudzin \u0026amp; M. Sochaki).\u003cbr\u003e \u003cbr\u003e The Biological Activity of Phosphono- and Phosphinopeptides (P. Kafarski \u0026amp; B. Lejezak).\u003cbr\u003e \u003cbr\u003e Aminophosphonic and Aminophosphinic Acids and their Derivatives as Agrochemicals (H. Hudson).\u003cbr\u003e \u003cbr\u003e Neuroactive Aminophosphonic and Aminophosphinic Acid Derivatives (D. Jane).\u003cbr\u003e \u003cbr\u003e Aminophosphonic and Aminophosphinic Acid Derivatives in the Design of Transition State Analogue Inhibitors: Biomedical Opportunities and Limitations (J. Oleksyszyn).\u003cbr\u003e \u003cbr\u003e Aminophosphonic and Aminophosphinic Acids in the Design and Synthesis of HIV Protease Inhibitors (A. Peyman).\u003cbr\u003e \u003cbr\u003e Aminophosphonic Acid Derivatives as Antithrombotic Agents (D. Green, et al.).\u003cbr\u003e \u003cbr\u003e Aminophosphonic and Aminophosphinic Acid Derivatives as Inhibitors of Human Collagenase (R. Markwell).\u003cbr\u003e \u003cbr\u003e Index.  \u003cp\u003e\"...will be useful for introducing new workers to these fields, as well as occupying an important place on many reference bookshelves.\" (\u003cem\u003eApplied Organometallic Chemistry,\u003c\/em\u003e Vol 14, 2000)   \u003c\/p\u003e\u003cp\u003eValery P. Kukhar is the author of Aminophosphonic and Aminophosphinic Acids: Chemistry and Biological Activity, published by Wiley. Harry R. Hudson is the author of Aminophosphonic and Aminophosphinic Acids: Chemistry and Biological Activity, published by Wiley.  The key role of naturally-occurring amino acids in the chemistry of life and as structural units in peptides, proteins and enzymes has led to intense interest in the chemistry and biological activity of synthetic analogues. The phosphorus analogues of the amino acids have attracted a particular interest in the fields of research directed at the discovery, understanding and modification of physiological processes. Aminophosphonic and Aminophosphinic Acids provides a comprehensive insight into the chemistry and biological activity of these compounds. Separate chapters are devoted to naturally-occurring derivatives, synthetic procedures, structural, spectroscopic and analytical aspects, metal complexes, agrochemicals, neuroactive compounds and biomedical applications and transition-state analogue enzyme inhibitors, with particular emphasis on inhibitors of HIV protease, thrombin and human collagenase. Aminophosphonic and Aminophosphinic Acids is a valuable source of information for researchers working with these types of compounds in biomedical and agrochemical industries and all others working with synthetic analogues of biologically important molecules.\u003c\/p\u003e","brand":"Wiley","offers":[{"title":"Default Title","offer_id":47988721058021,"sku":"NP9780471891499","price":907.95,"currency_code":"USD","in_stock":false}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/1842\/7735\/files\/9780471891499.jpg?v=1761781328","url":"https:\/\/k12savings.com\/es\/products\/aminophosphonic-and-aminophosphinic-acids-isbn-9780471891499","provider":"K12savings","version":"1.0","type":"link"}