Advances Against Aspergillosis II

Aspergillosis, the leading fungal cause of mortality in immunocompromised patients, presents a serious worldwide challenge—particularly in the face of increasing antifungal resistance. Bringing together the world’s leaders in the Aspergillus and aspergillosis fields to promote cross-disciplinary collaboration among clinicians, industry, and scientific experts, the “Advances Against Aspergillosis” conference was held January 26–28, 2012 in Istanbul, Turkey.

This second of two Annals volumes contains short reviews encapsulating recent findings in the basic science of aspergillosis. Among the topics included are the evolution of modular conidiophore development in the aspergilli; diverse applications of RNA-seq for functional genomics studies in Aspergillus fumigatus; protein targets for broad-spectrum mycosis vaccines: quantitative proteomic analysis of Aspergillus and Coccidioides; activation of the neutrophil NADPH oxidase by A. fumigatus; and cell biology of the innate immune response to A. fumigatus.

NOTE: Annals volumes are available for sale as individual books or as a journal. For information on institutional journal subscriptions, please visit: http://ordering.onlinelibrary.wiley.com/subs.asp?ref=1749-6632&doi=10.111/(ISSN)1749-6632.

ACADEMY MEMBERS: Please contact the New York Academy of Sciences directly to place your order (www.nyas.org). Members of the New York Academy of Science receive full-text access to Annals online and discounts on print volumes. Please visit http://www.nyas.org/MemberCenter/Join.aspx for more information on becoming a member.

Preface for Advances against aspergillosis / Karl V. Clemons, David S. Perlin, and Malcolm Richardson

Evolution of modular conidiophore development in the aspergilli / Steven D. Harris

Aspergillus flavus diversity on crops and in the environment can be exploited to reduce aflatoxin exposure and improve health / Hillary L. Mehl [and others]

Current section and species complex concepts in Aspergillus : recommendations for routine daily practice / Ana Alastruey-Izquierdo, Emilia Mellado, and Manuel Cuenca-Estrella

The diverse applications of RNA-seq for functional genomic studies in Aspergillus fumigatus / Antonis Rokas [and others]

Conservation in Aspergillus fumigatus of pH-signaling seven transmembrane domain and arrestin proteins, and implications for drug discovery / Elaine M. Bignell

Protein targets for broad-spectrum mycosis vaccines : quantitative proteomic analysis of Aspergillus and Coccidioides and comparisons with other fungal pathogens / Jackson Champer [and others]

Inflammation in aspergillosis : the good, the bad, and the therapeutic / Agostinho Carvalho [and others]

Pattern recognition receptors and their role in invasive aspergillosis / Mark S. Gresnigt, Mihai G. Netea, and Frank L. van de Veerdonk

Activation of the neutrophil NADPH oxidase by Aspergillus fumigatus / Keith B. Boyle, Len R. Stephens, and Phillip T. Hawkins

The top three areas of basic research on Aspergillus fumigatus in 2011 / Nir Osherov

The cell biology of the innate immune response to Aspergillus fumigatus / Michael K. Mansour, Jenny M. Tam, and Jatin M. Vyas

Karl V Clemons, Stanford University, Stanford, California.

Malcolm Richardson, University of Manchester, Manchester, United Kingdom.

David S Perlin, UMDNJ-New Jersey Medical School, Newark, New Jersey.