{"product_id":"advanced-drug-delivery-isbn-9781118022665","title":"Advanced Drug Delivery","description":"\u003cp\u003eProvides both fundamentals and new and emerging applications\u003c\/p\u003e \u003cp\u003e\u003ci\u003eAdvanced Drug Delivery\u003c\/i\u003e brings readers fully up to date with the state of the science, presenting the basics, formulation strategies, and therapeutic applications of advanced drug delivery. The book demonstrates how core concepts of pharmaceutical sciences, chemistry, and molecular biology can be combined and applied in order to spark novel ideas to design and develop advanced drug delivery systems for the treatment of a broad range of human diseases.\u003c\/p\u003e \u003cp\u003e\u003ci\u003eAdvanced Drug Delivery\u003c\/i\u003e features contributions from an international team of pharmaceutical scientists. Chapters reflect a thorough review and analysis of the literature as well as the authors' firsthand experience developing drug delivery systems. The book is divided into four parts:\u003c\/p\u003e \u003cul\u003e \u003cli\u003e\n\u003cb\u003ePart I, Introduction and Basics of Advanced Drug Delivery,\u003c\/b\u003e explores physiological barriers, stability, transporters, and biomaterials in drug delivery\u003c\/li\u003e \u003cli\u003e\n\u003cb\u003ePart II, Strategies for Advanced Drug Delivery,\u003c\/b\u003e offers tested and proven strategies for advanced delivery of both small molecules and macromolecules\u003c\/li\u003e \u003cli\u003e\n\u003cb\u003ePart III, Translational Research of Advanced Drug Delivery,\u003c\/b\u003e focuses on regulatory considerations and translational applications of advanced drug delivery systems for the treatment of cardiovascular diseases, cancer, sexually transmitted diseases, ophthalmic diseases, and brain diseases\u003c\/li\u003e \u003cli\u003e\n\u003cb\u003ePart IV, Future Applications of Advanced Drug Delivery in Emerging Research Areas,\u003c\/b\u003e examines stem cell research, cell-based therapeutics, tissue engineering, and molecular imaging\u003c\/li\u003e \u003c\/ul\u003e \u003cp\u003eEach chapter provides objectives and assessment questions to help readers grasp key concepts and assess their knowledge as they progress through the book.\u003c\/p\u003e \u003cp\u003e\u003ci\u003eAdvanced Drug Delivery\u003c\/i\u003e is recommended for graduates and upper-level undergraduates in the pharmaceutical sciences who need a solid foundation in the basics. It is also recommended for pharmaceutical professionals who want to take advantage of new and emerging applications in advanced drug delivery systems.\u003c\/p\u003e  \u003cp\u003e\u003cb\u003ePREFACE xi\u003c\/b\u003e\u003c\/p\u003e \u003cp\u003e\u003cb\u003eABOUT THE AUTHORS xiii\u003c\/b\u003e\u003c\/p\u003e \u003cp\u003e\u003cb\u003eCONTRIBUTORS xv\u003c\/b\u003e\u003c\/p\u003e \u003cp\u003e\u003cb\u003ePART I INTRODUCTION AND BASICS OF ADVANCED DRUG DELIVERY 1\u003c\/b\u003e\u003c\/p\u003e \u003cp\u003e\u003cb\u003e1 Physiological Barriers in Advanced Drug Delivery: Gastrointestinal Barrier 3\u003c\/b\u003e\u003cbr\u003e \u003ci\u003eD. Alexander Oh and Chi H. Lee\u003c\/i\u003e\u003c\/p\u003e \u003cp\u003e\u003cb\u003e2 Solubility and Stability Aspects in Advanced Drug Delivery 21\u003c\/b\u003e\u003cbr\u003e \u003ci\u003eHoo-Kyun Choi, Robhash K. Subedi, and Chi H. Lee\u003c\/i\u003e\u003c\/p\u003e \u003cp\u003e\u003cb\u003e3 The Role of Transporters and the Efflux System in Drug Delivery 47\u003c\/b\u003e\u003cbr\u003e \u003ci\u003eVarun Khurana, Dhananjay Pal, Mukul Minocha, and Ashim K. Mitra\u003c\/i\u003e\u003c\/p\u003e \u003cp\u003e\u003cb\u003e4 Biomaterial in Advanced Drug Delivery 75\u003c\/b\u003e\u003cbr\u003e \u003ci\u003eMegha Barot, Mitesh Patel, Xiaoyan Yang, Wuchen Wang, and Chi H. Lee\u003c\/i\u003e\u003c\/p\u003e \u003cp\u003e\u003cb\u003ePART II STRATEGIES FOR ADVANCED DRUG DELIVERY 103\u003c\/b\u003e\u003c\/p\u003e \u003cp\u003e\u003cb\u003e5 Strategies of Drug Targeting 105\u003c\/b\u003e\u003cbr\u003e \u003ci\u003eRavi S. Shukla, Zhijin Chen, and Kun Cheng\u003c\/i\u003e\u003c\/p\u003e \u003cp\u003e\u003cb\u003e6 Prodrug and Bioconjugation 123\u003c\/b\u003e\u003cbr\u003e \u003ci\u003eRamya Krishna Vadlapatla, Sujay Shah, Aswani Dutt Vadlapudi, and Ashim K. Mitra\u003c\/i\u003e\u003c\/p\u003e \u003cp\u003e\u003cb\u003e7 Nanoscale Drug Delivery Systems 141\u003c\/b\u003e\u003cbr\u003e \u003ci\u003eMitan R. Gokulgandhi, Ashaben Patel, Kishore Cholkar, Megha Barot, and Ashim K. Mitra\u003c\/i\u003e\u003c\/p\u003e \u003cp\u003e\u003cb\u003e8 Stimuli-Responsive Target Strategies 157\u003c\/b\u003e\u003cbr\u003e \u003ci\u003eChi H. Lee\u003c\/i\u003e\u003c\/p\u003e \u003cp\u003e\u003cb\u003e9 Implants 183\u003c\/b\u003e\u003cbr\u003e \u003ci\u003eAswani Dutt Vadlapudi, Ashaben Patel, Ramya Krishna Vadlapatla, Durga Paturi, and Ashim K. Mitra\u003c\/i\u003e\u003c\/p\u003e \u003cp\u003e\u003cb\u003e10 Aptamers in Advanced Drug Delivery 201\u003c\/b\u003e\u003cbr\u003e \u003ci\u003eWeiwei Gao, Omid C. Farokhzad, and Nazila Kamaly\u003c\/i\u003e\u003c\/p\u003e \u003cp\u003e\u003cb\u003e11 Nanofiber 219\u003c\/b\u003e\u003cbr\u003e \u003ci\u003eMegha Barot, Mitan R. Gokulgandhi, Animikh Ray, and Ashim K. Mitra\u003c\/i\u003e\u003c\/p\u003e \u003cp\u003e\u003cb\u003e12 Biomimetic Self-Assembling Nanoparticles 231\u003c\/b\u003e\u003cbr\u003e \u003ci\u003eMaxim G. Ryadnov\u003c\/i\u003e\u003c\/p\u003e \u003cp\u003e\u003cb\u003e13 Protein and Peptide Drug Delivery 241\u003c\/b\u003e\u003cbr\u003e \u003ci\u003eMitesh Patel, Megha Barot, Jwala Renukuntla, and Ashim K. Mitra\u003c\/i\u003e\u003c\/p\u003e \u003cp\u003e\u003cb\u003e14 Delivery of Nucleic Acids 257\u003c\/b\u003e\u003cbr\u003e \u003ci\u003eShaoying Wang, Bin Qin, and Kun Cheng\u003c\/i\u003e\u003c\/p\u003e \u003cp\u003e\u003cb\u003e15 Delivery of Vaccines 275\u003c\/b\u003e\u003cbr\u003e \u003ci\u003eHari R. Desu, Rubi Mahato, and Laura A. Thoma\u003c\/i\u003e\u003c\/p\u003e \u003cp\u003e\u003cb\u003ePART III TRANSLATIONAL RESEARCH OF ADVANCED DRUG DELIVERY 297\u003c\/b\u003e\u003c\/p\u003e \u003cp\u003e\u003cb\u003e16 Regulatory Considerations and Clinical Issues in Advanced Drug Delivery 299\u003c\/b\u003e\u003cbr\u003e \u003ci\u003eMei-Ling Chen\u003c\/i\u003e\u003c\/p\u003e \u003cp\u003e\u003cb\u003e17 Advanced Drug Delivery in Cancer Therapy 323\u003c\/b\u003e\u003cbr\u003e \u003ci\u003eWanyi Tai and Kun Cheng\u003c\/i\u003e\u003c\/p\u003e \u003cp\u003e\u003cb\u003e18 Advanced Delivery in Cardiovascular Diseases 341\u003c\/b\u003e\u003cbr\u003e \u003ci\u003eGayathri Acharya, Wuchen Wang, Divya Teja Vavilala, Mridul Mukherji, and Chi H. Lee\u003c\/i\u003e\u003c\/p\u003e \u003cp\u003e\u003cb\u003e19 Recent Advances in Ocular Drug Delivery 365\u003c\/b\u003e\u003cbr\u003e \u003ci\u003eVarun Khurana, Deep Kwatra, Vibhuti Agrahari, and Ashim K. Mitra\u003c\/i\u003e\u003c\/p\u003e \u003cp\u003e\u003cb\u003e20 Advanced Drug Delivery Against STD 381\u003c\/b\u003e\u003cbr\u003e \u003ci\u003eChi H. Lee\u003c\/i\u003e\u003c\/p\u003e \u003cp\u003e\u003cb\u003e21 Advanced Drug Delivery to the Brain 405\u003c\/b\u003e\u003cbr\u003e \u003ci\u003eNanda K. Mandava, Mitesh Patel, and Ashim K. Mitra\u003c\/i\u003e\u003c\/p\u003e \u003cp\u003e\u003cb\u003ePART IV FUTURE APPLICATIONS OF ADVANCED DRUG DELIVERY IN EMERGING RESEARCH AREAS 423\u003c\/b\u003e\u003c\/p\u003e \u003cp\u003e\u003cb\u003e22 Cell-Based Therapeutics 425\u003c\/b\u003e\u003cbr\u003e \u003ci\u003eZhaoyang Ye, Yan Zhou, Haibo Cai, and Wen-Song Tan\u003c\/i\u003e\u003c\/p\u003e \u003cp\u003e\u003cb\u003e23 Biomedical Applications and Tissue Engineering of Collagen 445\u003c\/b\u003e\u003cbr\u003e \u003ci\u003eChi H. Lee and Yugyung Lee\u003c\/i\u003e\u003c\/p\u003e \u003cp\u003e\u003cb\u003e24 Molecular Imaging of Drug Delivery 469\u003c\/b\u003e\u003cbr\u003e \u003ci\u003eZheng-Rong Lu\u003c\/i\u003e\u003c\/p\u003e \u003cp\u003e\u003cb\u003eANSWERS 489\u003c\/b\u003e\u003c\/p\u003e \u003cp\u003e\u003cb\u003eINDEX 511\u003c\/b\u003e\u003c\/p\u003e \u003cp\u003e\u003cbr\u003e  \u003c\/p\u003e  \u003cp\u003e“This book is a welcome addition to the range of study materials available at this level and can be unreservedly recommended to both aspiring and existing pharmaceutical professionals.”  \u003ci\u003e (\u003c\/i\u003e\u003ci\u003eChemMedChem\u003c\/i\u003e, 1 January 2015)\u003c\/p\u003e \u003cp\u003e“A suitable text for graduate and advanced undergraduate students, the book is logically divided into four sections: fundamentals, delivery approaches, disease applications, and future directions. Discussing design, in vitro studies, clinical evaluation, and regulatory approval, each chapter includes objectives and assessment questions.”  (\u003ci\u003eNewbooks.lib\u003c\/i\u003e, 11 September 2014\u003c\/p\u003e  \u003cp\u003e\u003cb\u003eASHIM K. MITRA, PhD,\u003c\/b\u003e is Chairman of Pharmaceutical Sciences at the University of Missouri-Kansas City. Dr. Mitra is also a University of Missouri Curators' Professor and has more than thirty years of experience in the field of ocular drug delivery and disposition. He has been the recipient of research awards from the NIH, AAPS, AACP, ARVO, and other pharmaceutical organizations.\u003c\/p\u003e \u003cp\u003e\u003cb\u003eCHI H. LEE, PhD,\u003c\/b\u003e is Professor of Pharmaceutical Sciences at the University of Missouri-Kansas City, where he teaches undergraduate and graduate pharmacy courses. His research focuses on elucidation of pathological mechanisms and formulation development of microbicidal and cardiovascular devices.\u003c\/p\u003e \u003cp\u003e\u003cb\u003eKUN CHENG, PhD,\u003c\/b\u003e is Associate Professor of Pharmaceutical Sciences at the University of Missouri-Kansas City. His research seeks to develop novel drug delivery systems for siRNA and small molecule drugs. Dr. Cheng is the recipient of the 2011 American Association of Pharmaceutical Scientists (AAPS) New Investigator Grant Award in Pharmaceutics and Pharmaceutical Technologies.\u003c\/p\u003e  \u003cp\u003eProvides both fundamentals and new and emerging applications\u003c\/p\u003e \u003cp\u003e\u003ci\u003eAdvanced Drug Delivery\u003c\/i\u003e brings readers fully up to date with the state of the science, presenting the basics, formulation strategies, and therapeutic applications of advanced drug delivery. The book demonstrates how core concepts of pharmaceutical sciences, chemistry, and molecular biology can be combined and applied in order to spark novel ideas to design and develop advanced drug delivery systems for the treatment of a broad range of human diseases.\u003c\/p\u003e \u003cp\u003e\u003ci\u003eAdvanced Drug Delivery\u003c\/i\u003e features contributions from an international team of pharmaceutical scientists. Chapters reflect a thorough review and analysis of the literature as well as the authors' firsthand experience developing drug delivery systems. The book is divided into four parts:\u003c\/p\u003e \u003cul\u003e \u003cli\u003e\n\u003cb\u003ePart I, Introduction and Basics of Advanced Drug Delivery,\u003c\/b\u003e explores physiological barriers, stability, transporters, and biomaterials in drug delivery\u003c\/li\u003e \u003cli\u003e\n\u003cb\u003ePart II, Strategies for Advanced Drug Delivery,\u003c\/b\u003e offers tested and proven strategies for advanced delivery of both small molecules and macromolecules\u003c\/li\u003e \u003cli\u003e\n\u003cb\u003ePart III, Translational Research of Advanced Drug Delivery,\u003c\/b\u003e focuses on regulatory considerations and translational applications of advanced drug delivery systems for the treatment of cardiovascular diseases, cancer, sexually transmitted diseases, ophthalmic diseases, and brain diseases\u003c\/li\u003e \u003cli\u003e\n\u003cb\u003ePart IV, Future Applications of Advanced Drug Delivery in Emerging Research Areas,\u003c\/b\u003e examines stem cell research, cell-based therapeutics, tissue engineering, and molecular imaging\u003c\/li\u003e \u003c\/ul\u003e \u003cp\u003eEach chapter provides objectives and assessment questions to help readers grasp key concepts and assess their knowledge as they progress through the book.\u003c\/p\u003e \u003cp\u003e\u003ci\u003eAdvanced Drug Delivery\u003c\/i\u003e is recommended for graduates and upper-level undergraduates in the pharmaceutical sciences who need a solid foundation in the basics. It is also recommended for pharmaceutical professionals who want to take advantage of new and emerging applications in advanced drug delivery systems.\u003c\/p\u003e","brand":"Wiley","offers":[{"title":"Default Title","offer_id":47988666138853,"sku":"NP9781118022665","price":117.0,"currency_code":"USD","in_stock":false}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/1842\/7735\/files\/9781118022665.jpg?v=1761781181","url":"https:\/\/k12savings.com\/es\/products\/advanced-drug-delivery-isbn-9781118022665","provider":"K12savings","version":"1.0","type":"link"}