Haematology

The definitive overview of haematology and its recent developments

Haematology has advanced considerably in recent decades. As new developments emerge, there is a continuous need for an accessible and up-to-date survey for medical students, discussing the major haematological disorders, their clinical presentations, their treatments, and more.

Written by specialists with an interest in medical education, Lecture Notes: Haematology is a succinct, highly illustrated student guide to the essentials of this important field. It integrates the physiological, pathological, and clinical dimensions of haematology in a single comprehensive guide, and provides medical students and early-career clinicians with the core knowledge required to succeed in the subject. The 11th edition of this guide includes updated sections and expanded chapters detailing the newest advances in the field.

In this 11th edition of Lecture Notes: Haematology, readers will also find:

• Discussion of both pathogenesis and management of all major haematological disorders
• Online clinical cases with >150 multiple choice questions to allow you to test and apply your knowledge

Lecture Notes: Haematology, 11th edition isa valuable resource for medical students and junior doctors looking to increase their expertise in this medical specialty.

Preface vii

About the companion website ix

1 An introduction to haematopoiesis 1

2 The blood count in health and disease 15

3 Anaemia: general principles 23

4 Haemolytic anaemias 39

5 Disorders of globin synthesis 55

6 An introduction to haematological malignancies 71

7 Cellular and molecular investigations in haematology 79

8 Neoplastic disorders of myeloid cells 91

9 Neoplastic disorders of lymphoid cells 105

10 Plasma cell myeloma and other paraproteinaemias 121

11 Aplastic anaemia and pure red cell aplasia 131

12 Stem cell transplantation and cellular therapy 137

13 Haemostasis and bleeding disorders 147

14 Thrombosis and anticoagulant therapy 163

15 Blood groups and blood transfusion 173

Index 187

DEBORAH HAY, DPhil, MRCP, FRCPath, Clinical Tutor for Laboratory Medicine, Nuffield Department of Clinical Laboratory Science and Radcliffe Department of Medicine, University of Oxford, Oxford; Honorary Consultant Haematologist, Cambridge University Hospitals NHS Foundation Trust, Cambridge, UK.

ANDREW KING, DPhil, MRCP, FRCPath, Consultant Haematologist, Cambridge University Hospitals NHS Foundation Trust, Cambridge, UK.

MICHAEL DESBOROUGH, DPhil, MRCP, FRCPath, Consultant Haematologist, Oxford University Hospitals NHS Foundation Trust, Oxford; Radcliffe Department of Medicine, University of Oxford, Oxford, UK.

HAEMATOLOGY
Lecture Notes 11th Edition

The Lecture Notes series provide concise, yet thorough, introductions to core areas of the undergraduate curriculum, covering both the basic science and the clinical approaches that all medical students and junior doctors need to know.

For more information on all titles in the Lecture Notes series, please visit: www.wiley.com/en-gb/Lecture+Notes-c-2593

Lecture Notes: Haematology provides the basic subject knowledge required for understanding the pathogenesis and management of haematological disorders. This succinct, fully illustrated guide integrates all essential physiological, pathological, and clinical aspects of haematology in one easy-to-use volume.

Now in its eleventh edition, Lecture Notes: Haematology includes new material on molecular and cellular diagnostics, new self-assessment questions in every chapter, and expanded coverage of haemostasis, anticoagulation, stem cell transplantation, and innovative cellular therapies for haematological malignancies.

Featuring an updated companion website with over 150 multiple-choice questions across a series of evolving clinical cases, Lecture Notes: Haematology, 11th Edition is a must-have resource for medical students and junior doctors looking to increase their expertise in this important medical specialty.

Haematology Lecture Notes, Eleventh Edition is a must-have guide for medical students and junior doctors in Haematology placements and preparing for clinical examinations.

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