Chemistry of Organo-hybrids

This book provides readers with a one-stop entry into the chemistry of varied hybrids and applications, from a molecular synthetic standpoint

• Describes introduction and effect of organic structures on specific support components (carbon-based materials, proteins, metals, and polymers).
• Chapters cover hot topics including nanodiamonds, nanocrystals, metal-organic frameworks, peptide bioconjugates, and chemoselective protein modification
• Describes analytical techniques, with pros and cons, to validate synthetic strategies
• Edited by internationally-recognized chemists from different backgrounds (synthetic polymer chemistry, inorganic surfaces and particles, and synthetic organic chemistry) to pull together diverse perspectives and approaches

Preface vii

Contributors ix

1 COVALENT ORGANIC FUNCTIONALIZATION AND CHARACTERIZATION OF CARBON NANOTUBES 1
Cécilia Ménard-Moyon

2 FUNCTIONALIZED GRAPHENES 36
Iban Azcarate, David Lachkar, Emmanuel Lacôte, Jennifer Lesage de la Haye, and Anne-Laure Vallet

3 NANODIAMONDS: EMERGENCE OF FUNCTIONALIZED DIAMONDOIDS AND THEIR UNIQUE APPLICATIONS 69
Maria A. Gunawan, Paul Kahl, Didier Poinsot, Bruno Domenichini, Peter R. Schreiner, Andrey A. Fokin, and Jean-Cyrille Hierso

4 TITANIA-BASED HYBRID MATERIALS: FROM MOLECULAR PRECURSORS TO THE CONTROLLED DESIGN OF HIERARCHICAL HYBRID MATERIALS 114
Laurence Rozes, Loïc D’Arras, Chloé Hoffman, François Potier, Niki Halttunen, and Lionel Nicole

5 FUNCTIONALIZATION OF ZIRCONIUM OXIDE SURFACES 168
Marc Petit and Julien Monot

6 FUNCTIONAL METAL–ORGANIC FRAMEWORKS: SYNTHESIS AND REACTIVITY 200
Flavien L. Morel, Xiaoying Xu, Marco Ranocchiari, and Jeroen A. van Bokhoven

7 SURFACE CHEMISTRY OF COLLOIDAL SEMICONDUCTOR NANOCRYSTALS: ORGANIC, INORGANIC, AND HYBRID 233
Richard Brutchey, Zeger Hens, and Maksym V. Kovalenko

8 COVALENT ORGANIC FUNCTIONALIZATION OF NUCLEIC ACIDS 272
Michel Arthur and Mélanie Etheve-Quelquejeu

9 CHEMOSELECTIVE PROTEIN MODIFICATIONS: METHODS AND APPLICATIONS FOR THE FUNCTIONALIZATION OF VIRAL CAPSIDS 299
Divya Agrawal and Christian P. R. Hackenberger

10 CYCLODEXTRINS–METAL HYBRIDS 349
Maxime Guitet, Mickaël Ménand, and Matthieu Sollogoub

11 POST-FUNCTIONALIZATION OF POLYMERS VIA ORTHOGONAL LIGATION CHEMISTRY 395
Anja S. Goldmann, M. Glassner, Andrew J. Inglis, and Christopher Barner-Kowollik

12 POLYMER–PROTEIN/PEPTIDE BIOCONJUGATES 466
Paul Wilson, Julien Nicolas, and David M. Haddleton

13 HYBRID MATERIALS BUILT FROM (PHOSPHORUS) DENDRIMERS 503
Anne-Marie Caminade, Beatrice Delavaux-Nicot, and Jean-Pierre Majoral

Index

Bernadette Charleux is a Professor at the Claude Bernard Lyon 1 University, and a Senior Member of the Institut Universitaire de France.

Christophe Copéret (CCH) is a Professor in the Department of Chemistry (Institute of Inorganic chemistry) at ETH Zürich.

Emmanuel Lacôte is CNRS Research Director at CPE Lyon. A One-Stop Entry into Hybrid Chemistry and Applications

Hybrid materials are made by linking molecules to supports in order to create optimal combinations and enhanced functionality. Successful synthesis requires a deep understanding of molecular-level events and the ability to control them through design. This book acts a step-by-step guide for designing organo-hybrid materials. Focusing on a molecular synthetic approach, chapters provide:

• Up-to-date strategies and methods of controlling functions of attachments
• Information about common classes of supports, including polymers and biopolymers, carbons, oxides, and nanostructures
• Details of specific supports, their synthesis, installation of organic substituents, effects on properties.
• Analytical techniques, with pros and cons, to validate synthetic strategies
• Hot topics: nanodiamonds, metal-organic frameworks, and chemoselective postsynthetic protein modification.

Combining the perspectives of internationally-recognized chemists from synthetic, polymer, organic, and inorganic research backgrounds, this book pulls together diverse approaches to provide a well-rounded, interdisciplinary knowledge base about organo-hybrid materials.