Aza-Crown Macrocycles, Volume 51

The Chemistry of Heterocyclic Compounds, since its inception, has been recognized as a cornerstone of heterocyclic chemistry. Each volume attempts to discuss all aspects – properties, synthesis, reactions, physiological and industrial significance – of a specific ring system. To keep the series up-to-date, supplementary volumes covering the recent literature on each individual ring system have been published. Many ring systems (such as pyridines and oxazoles) are treated in distinct books, each consisting of separate volumes or parts dealing with different individual topics. With all authors are recognized authorities, the Chemistry of Heterocyclic Chemistry is considered worldwide as the indispensable resource for organic, bioorganic, and medicinal chemists.

I. Aza-Crown Macrocycles: An Overview 1

II. Preparation of Starting Materials 31

III. General Synthetic Methods for the Polyaza-Crown Macrocycles 73

IV. Common Methods for the Formation of Polyaza Macrocyclic Rings 123

V. Monoaza-Crown Macrocycles 173

VI. Diaza-Crown Macrocycles 245

VII. Polyaza-Crown Macrocycles 349

VIII. Benzoaza-Crown Macrocycles 401

IX. Aza-Crown Macrocycles Containing Other Heteroatoms in the Macroring 471

X. Aliphatic Peraza-Crown Macrocycles (Cyclams) 539

XI. Peraza-Cyclophanes 693

XII. Aza- And Peraza-Crown Macrocycles as Part of Macromolecular Compounds 755

XII. Some Practical Approaches to the Aza-Crown Macrocycles 795

Author Index 805

Subject Index 873

Jerald S. Bradshaw is the editor of Aza-Crown Macrocycles, Volume 51, published by Wiley.

Krzysztof E. Krakowiak is the editor of Aza-Crown Macrocycles, Volume 51, published by Wiley.

Reed M. Izatt is the editor of Aza-Crown Macrocycles, Volume 51, published by Wiley.