A Beginner's Guide to Mass Spectral Interpretation

This book is a logical, step-by-step guide to identification of organic compounds by mass spectrometry. The book is organized into chapters covering the major types of organic compounds, including alcohols, acids and esters, aldehydes and ketones, ethers, hydrocarbons, halogenated compounds, amines and amides, and sulfur-containing compounds. In each chapter, the mechanisms of the major fragmentation pathways are discussed, with reference to several simple sample compounds. By teaching the user to recognize typical fragmentations, the book removes the need to search databases, often limited, of electronic spectra. Key features of the book include:
* 200 representative spectra of common organic compounds
* Functional group approach to mass spectra interpretation
* Appendix of 'unknown' spectra with step-by-step guide to identification
This book is a must for anyone who needs to identify organic molecules by mass spectrometry but does not need to know the detailed workings of a mass spectrometer.Die Massenspektrometrie ist eine der wenigen Techniken, mit denen man organische Verbindungen eindeutig identifizieren kann. Dieses Buch behandelt die Interpretation von Massenspektren organischer Verbindungen, und zwar auf einem für Studienanfänger und Fortgeschrittene geeigneten Niveau. Die verschiedenen organischen Verbindungen werden in einzelnen Kapiteln besprochen, wobei der Schwerpunkt auf einem verbindungsspezifischen Ansatz zur Interpretation von Massenspektren liegt. Einfach und verständlich geschrieben mit mehr als 120 repräsentativen Spektren, ist dieses Werk speziell für Studierende im 2. und 3. Studienjahr sowie für Neulinge auf diesem Gebiet gedacht. (01/98)

Acknowledgements ix

Introduction xi

Chapter 1 Isotope Abundances and How We Use Them 1

Chapter 2 Identification of the Molecular Ion 5

Chapter 3 General Interpretation Procedures 9

Chapter 4 Hydrocarbons 22

Chapter 5 Halogenated Hydrocarbons 47

Chapter 6 Alcohols 60

Chapter 7 Ethers and Phenols 72

Chapter 8 Aldehydes and Ketones 79

Chapter 9 Esters and Acids 91

Chapter 10 Nitrogen-Containing Compounds 106

Chapter 11 Thiols and Thioethers 117

Chapter 12 Heterocyclic Compounds 126

Chapter 13 Unknowns 133

Appendix Detailed Solutions to Unknowns 153

Bibliography 180

Topic Index 183

Index of Compounds and Spectra 184

"... an ideal introduction to the topic of spectral interpretation." (Chromatographia, July 2000)

Terrence A. Lee is the author of A Beginner's Guide to Mass Spectral Interpretation, published by Wiley. This book is a logical, step-by-step guide to identification of organic compounds by mass spectrometry. The book is organized into chapters covering the major types of organic compounds, including alcohols, acids and esters, aldehydes and ketones, ethers, hydrocarbons, halogenated compounds, amines and amides, and sulfur-containing compounds. In each chapter, the mechanisms of the major fragmentation pathways are discussed, with reference to several simple sample compounds. By teaching the user to recognize typical fragmentations, the book removes the need to search databases, often limited, of electronic spectra. Key features of the book include:
* 200 representative spectra of common organic compounds
* Functional group approach to mass spectra interpretation
* Appendix of 'unknown' spectra with step-by-step guide to identification
This book is a must for anyone who needs to identify organic molecules by mass spectrometry but does not need to know the detailed workings of a mass spectrometer.