Water in Biomaterials Surface Science

Presents the latest ideas and research on molecular hydration and hydration forces, and how they determine the interaction between water molecules and biomaterials surfaces. Consisting of three sections; theoretical aspects, analytical aspects and practical applications, it begins by placing the properties of water in a proper molecular perspective.

The analytical aspects and practical applications offer a complete overview with new insights into the biomaterials/water interface by:

- Discussing the latest approaches to the characterisation of water at interfaces and surface modification of biomaterials

- Examining the problems related to the understanding and characterisation of interfacial water

- Providing new perspectives of the interfacial interactions between materials and the physiological aqueous environment

An invaluable resource for researchers in biomaterials surface science and the biotechnology industry.Theorie, Analytik, Praxis: Dieser Band behandelt alle wesentlichen Aspekte eines relativ jungen Forschungsgebietes, das sich mit Wechselwirkungen an Grenzflächen zwischen biologischen Materialien (u.a. Polysacchariden, Polyethylenoxid, Proteinen, Kohlenhydraten) und Wasser beschäftigt. Diskutiert werden Konsequenzen für Biotechnologie, Medizin und für die Herstellung von Beschichtungen.

Contributors vii

Introduction ix
M. Morra

Theoretical Aspects 1

1 Biological Properties of Water 3
E. A. Vogler

2 Theoretical and Computational Methods of Biomolecular Hydration 25
A. E. Garcia

3 Molecular Dynamics Simulations of Carbohydrate – Water Interactions 53
S. B. Engelsen

4 Statistical Thermodynamics of Fluids with Orientation-Dependent Properties and its Application to Water at Interfaces 91
N.A.M. Besseling

5 Solvation Interactions for Protein Adsorption to Biomaterial Surfaces 127
J. H. Lee, T. Li and K. Park

Analytical Aspects 147

6 On the Origin of Water Wetting Terminology 149
E. A. Volger

7 The Evaluation of Electron-Donor and Electron-Acceptor Properties and their Role in the Interaction of Solid Surfaces with Water 183
C Della Volpe and S. Siboni

8 Vibrational Spectroscopy for Water at Interfaces 215
Y. R. Shen

9 Atomic Force Microscope Analysis of Water-Mediated Interfacial Interactions 245
H. J. Butt and V. Franz

Practical Applications 267

10 How Water Wets Biomaterial Surfaces 269
E. A. Vogler

11 Super-Hydrophilic Surfaces for Biomedical Applications 291
Y. Ikada

12 Poly(ethylene oxide) Coated Surfaces 307
M. Morra

13 The Role of Water in the Surface Properties of Phospholipid Polymers 333
K. Ishihara

14 Hydrophilic Polysaccharides Coatings 353
M. Morra and C. Cassinelli

Index 389

"This would be a valuable book. UK reviewer", , , #"This is novel subject for a book.......there is certainly nothing like it out there. Dr Morra is an outstanding thinker. US reviewer", , , #"I think the title is a very timely one. Scandinavian reviewer", , , #

M. Morra is the author of Water in Biomaterials Surface Science, published by Wiley. Water in Biomaterials Surface Science presents the latest ideas and research on molecular hydration and hydration forces, and how they determine the interaction between water molecules and biomaterials surfaces. Split into three sections, theoretical, analytical and practical applications, it begins by discussing the relationship between the molecules of life and the molecular structure of water and how the latter determines forces at the solid/aqueous interface.

Sections two, analytical techniques, and three, practical applications, offer a complete overview and new insights into the biomaterials/water interface by:
* discussing the latest approaches to the characterisation of water at interfaces and surface modification of biomaterials

* examining the problems related to the understanding and characterisation of interfacial water

* providing new perspectives of the interfacial interactions between materials and the physiological aqueous environment
Written by an international team of scientists Water in Biomaterials Surface Science will be essential reading for researchers in biomaterials surface science, biomedical appliances and biotechnologists involved in the development of hydrophilic materials for biotechnological devices.