Organic Reactions, Volume 77

This new volume in the venerable Organic Reactions series comprises two chapters written in part by the inventors of the unique and important name reactions discussed in these chapters. The first chapter describes a truly remarkable transformation of carboxylic acid derivatives into heteroatom-substituted cyclopropanes, now known as Kulinkovich Cyclopropanation. The second chapter represents an homage to one of the giants of organic chemistry, Sir Derek H. R. Barton. This chapter covers the radical deoxygenation of secondary alcohols that has become known as the Barton-McCombie Reaction.

1. The Kulinkovich Cyclopropanation of Carboxylic Acid Derivatives 1
Jin Kun Cha and Oleg G. Kulinkovich

2. The Barton-Mccombie Reaction 161
Stuart W. McCombie, William B. Motherwell, and Matthew J. Tozer

Cumulative Chapter Titles By Volume 593

Author Index, Volumes 1–77 609

Chapter and Topic Index, Volumes 1–77 615

Scott E. Denmark received his undergraduate degree from the Massachusetts Institute of Technology in 1975 and his graduate degree (D.Sc. Tech.) from the ETH-Zürich in 1980. He joined the faculty at Illinois in the same year. His research interests are in structural, synthetic and mechanistic organic chemistry.