Practical Manual of Clinical Obesity

Practical Manual of Clinical Obesity provides practical, accessible and expert advice on the clinical diagnosis and management of obesity and will be your perfect go-to tool in the management of your patients.

Information is clear, didactic and attractively presented, with every chapter containing plenty of engaging text features such as key points, pitfall boxes, management flowcharts and case studies to enable a rapid
understanding of obesity diagnosis and management. Key clinical trials and major international society guidelines are referred to throughout.

Topics covered include:
• Assessment of the patient, including patient history, examination and investigations
• Patterns, risks and benefits of weight loss
• Evaluation of management options: diet, exercise, drugs, psychological treatments, and surgery
• Management of obesity related co-morbidities

Practical Manual of Clinical Obesity is ideal reading for endocrinologists of all levels, as well as all other health professionals who manage obese patients such as specialist nurses, dieticians, and GP’s with an interest in obesity management.

Preface vii

Part 1 The Biology of Obesity—Why It Occurs 1
Victor Lawrence, Section Editor

1 Energy Balance and Body Weight Homeostasis 3

2 The Genetic Basis of Obesity 13

3 Adipocyte Biology 25

4 Fetal and Infant Origins of Obesity 33

5 Metabolic Fuels and Obesity 41

Part 2 Clinical Management of the Obese Individual 51
Robert Kushner, Section Editor

6 Practical Guide to Clinical Assessment and Treatment Planning 53

7 Stages of Obesity and Weight Maintenanc 63

8 Dietary Management 71

9 Physical Activity and Exercise 81

10 Behavior Therapy 91

11 Pharmacotherapy 99

12 Surgery 109

Part 3 Clinical Management of Obesity-Related Co-morbidities 121
Sudhesh Kumar and Milan K. Piya, Section Editors

13 Diabetes and Metabolic Diseases 123

14 Obesity and Reproductive Health 133

15 Gastro-intestinal and Hepatobiliary Disease 141

16 Respiratory Disease 149

17 Obesity and Cardiovascular Disease 157

18 Obesity: Mental Health and Social Consequences 167

19 Obesity and Musculo-skeletal Disease 175

20 The Obese Patient in Hospital 181

Conversion Table 187

Index 189

"Written by experts in the field of obesity, this book covers an extremely important topic and all clinicians would benefit from reading it. Many health conditions can be linked to obesity, and many diseases are worsened by obesity. Teaching medical students, residents, and clinicians to treat and manage obesity is essential to the health of the world.” (Doody’s, 25 April 2014)

Robert Kushner, Professor of Medicine, Northwestern University Feinberg
School of Medicine, Chicago, USA

Victor Lawrence, Consultant Physician, Endocrinology and Diabetes,
St Mary’s Hospital, Newport, Isle of Wight, UK

Sudhesh Kumar, Professor of Medicine, Warwick Medical School,
University of Warwick, UK

Practical Manual of Clinical Obesity provides practical, accessible and expert advice on the clinical diagnosis and management of obesity and will be your perfect go-to tool in the management of your patients.

Information is clear, didactic and attractively presented, with every chapter containing plenty of engaging text features such as key points, pitfall boxes, management flowcharts and case studies to enable a rapid
understanding of obesity diagnosis and management. Key clinical trials and major international society guidelines are referred to throughout.

Topics covered include:
• Assessment of the patient, including patient history, examination and investigations
• Patterns, risks and benefits of weight loss
• Evaluation of management options: diet, exercise, drugs, psychological treatments, and surgery
• Management of obesity related co-morbidities

Practical Manual of Clinical Obesity is ideal reading for endocrinologists of all levels, as well as all other health professionals who manage obese patients such as specialist nurses, dieticians, and GP’s with an interest in obesity management.