Inorganic Biochemistry

The text will provide a set of problems covering mechanistic, structural and spectroscopic issues in inorganic chemistry. Specific areas to be covered include coordination chemistry, physiochemical aspects of solution chemistry, inorganic chemistry of biological systems (both natural biomolecules and bioinorganic models). Illustrative worked examples will be included. The problems will be categorized by topic chapters for ease of reference and use in courses. They will provide a valuable resource for instructors, providing a means of testing and developing the many principles covered in texts and advanced courses. Often students find it difficult to find practical problems to test the principles they have learned in class. This text will provide a series of questions to test understanding and worked examples as a pedagogical aid.Das erfolgreiche Werk des jungen, kreativen Autors jetzt in aktualisierter und korrigierter Auflage! Der Text wurde um Fragenkomplexe und Übungsbeispiele, teils mit Lösungen, erweitert;
dies empfiehlt ihn besonders zur Ergänzung einer Vorlesung. Fundamentals of Inorganic Biochemistry.

Experimental Methods.

Transport and Storage.

Metalloproteins and Metalloenzymes: (I) Oxygen Carriers and Hydrolases.

Metalloproteins and Metalloenzymes: (II) Redox Chemistry.

Alkali and Alkaline Earth Metals.

Metals in the Regulation of Biochemical Events.

Cell Toxicity and Chemotherapeutics.

Metal Complexes as Probes of Structure and Reactivity.

Case Studies.

Appendices.

Index. Aus dem Inhalt:

Introduction to Physicochemical and Spectroscopic Measurements/
Determining Molecular Structure in Solution/
Introduction to Kinetics and Mechanisms/
Investigating Mechanisms in Biological and Biocoordination Chemistry/
Regulation of Structure and Function -
Triggers, Switches, and Potential Gradients/
The Chemistry of Proteins and Nucleic Acids/
Special Topics at the Interface of Chemistry and Biology

J. A. Cowan is the author of Inorganic Biochemistry: An Introduction, 2nd Edition, published by Wiley. Inorganic Biochemistry An Introduction Second Edition J.A. Cowan Developments in the expanding field of inorganic biochemistry have led to major additions to this important teaching text. Like the earlier edition, the second edition does not aim to be comprehensive, but to illustrate the use of basic principles to tackle important problems in inorganic biochemistry. New features of the second edition include a section on basic kinetic and thermodynamic principles in the first chapter; coverage of iron response proteins, ribozymes, and radiopharmaceuticals; a new case study of bleomycin; a comprehensive set of problems and study questions; complete literature citations; and review questions after most of the summary sections. Inorganic Biochemistry: An Introduction, Second Edition will be of great value to senior-level undergraduates and beginning graduate students in inorganic chemistry and biochemistry. It also will be a valuable reference for biological, inorganic and organic chemists; chemical and environmental engineers; researchers in molecular biology and medical sciences; and biophysicists.