Catalyst Components for Coupling Reactions

• The long awaited Handbook for all synthetic chemists working on coupling reactions, compiling all major catalyst components in use in the area.
• Consists of a compilation of articles taken from the EROS database, with the inclusion of about 20 newly commissioned catalysts/pre-catalysts/ligands that have made an impact in this area of synthetic organic chemistry.
• Includes catalyst systems used in Heck, Kumada-Tamao-Corriu, Suzuki-Miyaura, Hiyama-Hatanaka, Negishi, Migita-Kosugi-Stille, Buchwald-Hartwig, and Tsuji-Trost coupling reactions.

Eine Zusammenstellung von Beiträgen aus der EROS-Datenbank, einschließlich der Betrachtung von 20 neu erforschten Prä-Katalysatoren, Katalysatoren oder Liganden mit besonderer Bedeutung in dem Fachgebiet. Preface.

Introduction.

Recent Review Articles and Monographs.

1-Adamantyl-di-tert-butylphosphine.

Benzylchlorobis(triphenylphosphine)palladium (II).

[1,1′-Biphenyl]-2-yldicyclohexylphosphine.

Carbonyl(chloro)bis(triphenylphosphine)rhodium(I).

Diacetatobis(tri=o-tolylphophine)palladium(II)

Encapsulated Palladium Catalysts.

Hydrotetrakis(triphenylphosphine)rhodium.

Ido(phenyl)bis(triphenylphosphine)palladium(II).

Lithium Trichloropalladate.

(Maleic anhydride)bis(triphenylphosphine)palladium,

Nickel.

Palladium(II) Acetate.

Silver(I) Oxide.

Tetrakis(acetonitrille)copper(I) Perchlorate.

Zinc/Nickel Couple.

List of Contributors.

Reagent Formula Index.

Subject Index.

"While a number of books and review articles describe the importance and application of different aspects of coupling reactions, this Handbook will be a compilation of all major catalyst components in use in the area, and is intended to guide the experimentalist and facilitate choice among the numerous reagents available for any one purpose." (Live-PR (EN), 16 March 2011)

Gary A. Molander is a Professor with the Department of Chemistry at the University of Pennsylvania in Philiadelphia, Pennsylvania. Among the myriad new methodological strategies developed over the past 50 years, none have impacted the construction of organic molecules as much as those transformations categorized as cross-coupling reactions. Most of these reactions rapidly assumed their current status as "name reactions", including the Suzuki-Miyaura, Negishi, Kumada-Tamao/Corriu, Stille/Migita-Kosugi, Tamao-Kumada/Hiyama-Hatanaka and Sonogashira cross-couplings, as well as the Mizoroki-Heck, Tsuji-Trost and Buchwald-Hartwig reactions. All cross-couplings are inextricably linked by one common theme: they employ catalyst systems comprised of various metal complexes and ligands that promote the reactions through catalytic cycles in which many of the individual steps are analogous. For this reason this Handbook focuses on the individual components of catalyst systems. Many of these may be organized into "super-families" of compounds that are constituted from similar molecular platforms. An attempt has been made to group these under a single parent compound.

All the information compiled in this volume is also available in electronic format on Wiley InterScience. The electronic Encyclopedia of Reagents for Organic Synthesis (e-EROS) includes all the reagents described in this volume plus many more reagents of other types and for other uses. e-EROS allows for both text and structure searches and has many new and updated entries added every year. For more information visit:

http://www.mrw.interscience.wiley.com/eros/